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astemizole_MCF7_UP

GeneID Mean_1 Mean_2 StDev_1 StDev_2 T-Statistic p-value SymbolDescription
1 8364 12.6 13.0 0.2 0.0 2.537 0.1207 HIST1H4C histone cluster 1, H4c
2 8366 13.3 13.4 0.2 0.1 0.481 0.6618 HIST1H4B histone cluster 1, H4b
3 8359 9.0 9.2 0.1 0.4 0.978 0.4276 HIST1H4A histone cluster 1, H4a
4 5366 8.3 9.1 0.1 0.1 7.879 0.0016 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
5 8361 10.9 11.9 0.2 0.1 7.517 0.0031 HIST1H4F histone cluster 1, H4f
6 8367 14.0 13.8 0.0 0.2 -1.139 0.3720 HIST1H4E histone cluster 1, H4e
7 8360 11.9 12.1 0.1 0.1 2.066 0.1077 HIST1H4D histone cluster 1, H4d
8 8362 12.9 13.7 0.1 0.1 8.034 0.0016 HIST1H4K histone cluster 1, H4k
9 8363 12.4 13.5 0.1 0.1 9.976 0.0006 HIST1H4J histone cluster 1, H4j
10 8294 11.7 12.2 0.2 0.1 4.937 0.0123 HIST1H4I histone cluster 1, H4i
11 8365 11.9 12.3 0.1 0.1 4.373 0.0126 HIST1H4H histone cluster 1, H4h
12 3976 4.9 4.8 1.4 0.3 -0.131 0.9067 LIF leukemia inhibitory factor
13 8368 11.4 11.6 0.2 0.2 1.038 0.3584 HIST1H4L histone cluster 1, H4l
14 7718 10.3 11.5 0.1 0.4 5.116 0.0324 ZNF165 zinc finger protein 165
15 7779 9.9 10.0 1.0 1.1 0.159 0.8812 SLC30A1 solute carrier family 30 (zinc transporter), member 1
16 56672 8.5 9.0 0.1 0.4 1.792 0.1975 AKIP1 A kinase (PRKA) interacting protein 1
17 23764 4.1 5.1 0.8 0.2 2.247 0.1414 MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
18 645745 13.8 15.1 0.8 0.1 2.860 0.1015 MT1HL1 metallothionein 1H-like 1
19 3309 9.7 10.4 0.4 0.1 2.829 0.0971 HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
20 8553 8.8 8.7 0.1 0.8 -0.307 0.7863 BHLHE40 basic helix-loop-helix family, member e40
21 1647 9.0 10.5 0.4 0.9 2.625 0.0821 GADD45A growth arrest and DNA-damage-inducible, alpha
22 4616 10.6 12.8 0.2 0.7 5.320 0.0250 GADD45B growth arrest and DNA-damage-inducible, beta
23 83729 3.8 4.6 1.1 0.8 1.017 0.3722 INHBE inhibin, beta E
24 3422 10.7 11.3 0.5 0.8 1.160 0.3215 IDI1 isopentenyl-diphosphate delta isomerase 1
25 5971 9.1 9.9 1.0 0.5 1.289 0.2869 RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
26 10150 8.2 7.4 0.1 0.5 -2.429 0.1181 MBNL2 muscleblind-like splicing regulator 2
27 57018 11.1 10.7 0.1 0.2 -2.815 0.0836 CCNL1 cyclin L1
28 1649 9.2 11.1 1.2 1.7 1.642 0.1826 DDIT3 DNA-damage-inducible transcript 3
29 54541 13.1 13.8 0.7 1.0 0.998 0.3785 DDIT4 DNA-damage-inducible transcript 4
30 1831 12.8 11.4 0.3 1.5 -1.526 0.2576 TSC22D3 TSC22 domain family, member 3
31 55062 11.8 11.1 0.1 0.1 -6.742 0.0028 WIPI1 WD repeat domain, phosphoinositide interacting 1
32 1185 6.4 6.2 0.1 0.4 -0.924 0.4455 CLCN6 chloride channel, voltage-sensitive 6
33 9871 8.4 10.2 0.4 0.1 8.369 0.0115 SEC24D SEC24 family member D
34 3156 10.8 11.7 0.1 0.4 3.833 0.0421 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
35 4494 12.5 11.8 1.2 0.6 -0.891 0.4407 MT1F metallothionein 1F
36 4495 2.2 2.7 0.0 0.9 0.920 0.4546 MT1G metallothionein 1G
37 7422 8.5 10.7 0.5 1.5 2.370 0.1188 VEGFA vascular endothelial growth factor A
38 11182 11.2 10.2 0.2 0.5 -2.944 0.0732 SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
39 4739 5.1 6.1 0.5 0.4 2.558 0.0645 NEDD9 neural precursor cell expressed, developmentally down-regulated 9
40 2669 4.3 5.3 0.6 1.0 1.452 0.2383 GEM GTP binding protein overexpressed in skeletal muscle
41 79094 5.2 9.4 1.8 1.2 3.408 0.0346 CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
42 10957 12.0 10.4 0.0 0.7 -3.893 0.0598 PNRC1 proline-rich nuclear receptor coactivator 1
43 6352 6.7 8.2 0.5 1.4 1.795 0.1867 CCL5 chemokine (C-C motif) ligand 5
44 81788 10.2 10.0 0.3 0.7 -0.464 0.6769 NUAK2 NUAK family, SNF1-like kinase, 2
45 4792 13.7 13.4 0.5 0.2 -0.924 0.4295 NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
46 10221 12.8 13.0 0.1 0.8 0.455 0.6926 TRIB1 tribbles pseudokinase 1
47 57761 14.1 15.5 0.8 1.2 1.788 0.1601 TRIB3 tribbles pseudokinase 3
48 3437 6.2 9.3 0.3 1.9 2.811 0.1014 IFIT3 interferon-induced protein with tetratricopeptide repeats 3
49 3433 6.4 8.7 0.4 1.3 2.865 0.0825 IFIT2 interferon-induced protein with tetratricopeptide repeats 2
50 3434 8.9 14.1 0.7 1.1 6.761 0.0043 IFIT1 interferon-induced protein with tetratricopeptide repeats 1
51 23586 6.6 8.0 0.2 0.3 6.593 0.0037 DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
52 4501 12.5 13.7 0.9 0.2 2.240 0.1443 MT1X metallothionein 1X
53 83988 3.4 2.8 0.1 0.0 -12.605 0.0025 NCALD neurocalcin delta
54 1959 3.3 3.1 0.6 0.5 -0.366 0.7328 EGR2 early growth response 2
55 1960 4.6 9.7 0.8 0.8 7.719 0.0015 EGR3 early growth response 3
56 1958 8.9 7.9 0.7 0.1 -2.652 0.1148 EGR1 early growth response 1
57 3725 9.2 10.3 0.7 0.3 2.573 0.0962 JUN jun proto-oncogene
58 1961 3.1 2.8 0.6 0.4 -0.837 0.4539 EGR4 early growth response 4
59 6713 12.6 12.2 0.3 0.7 -0.995 0.3970 SQLE squalene epoxidase
60 353189 4.1 5.0 0.2 0.3 4.033 0.0183 SLCO4C1 solute carrier organic anion transporter family, member 4C1
61 4496 2.6 2.5 0.3 0.1 -0.801 0.4879 MT1H metallothionein 1H
62 4783 10.4 11.2 0.1 0.7 1.943 0.1874 NFIL3 nuclear factor, interleukin 3 regulated
63 9518 12.5 13.3 1.1 1.1 0.891 0.4234 GDF15 growth differentiation factor 15
64 81631 10.6 11.4 0.1 0.8 1.634 0.2390 MAP1LC3B microtubule-associated protein 1 light chain 3 beta
65 1746 9.6 9.0 0.3 1.4 -0.770 0.5174 DLX2 distal-less homeobox 2
66 4131 4.7 6.0 0.3 1.4 1.676 0.2277 MAP1B microtubule-associated protein 1B
67 2353 7.0 8.7 0.4 0.7 3.877 0.0281 FOS FBJ murine osteosarcoma viral oncogene homolog
68 26471 14.7 15.2 1.2 1.8 0.347 0.7480 NUPR1 nuclear protein, transcriptional regulator, 1
69 8344 8.8 9.9 0.2 0.3 5.938 0.0085 HIST1H2BE histone cluster 1, H2be
70 8343 8.9 9.8 0.2 0.1 7.649 0.0092 HIST1H2BF histone cluster 1, H2bf
71 8339 10.0 10.4 0.1 0.1 6.734 0.0026 HIST1H2BG histone cluster 1, H2bg
72 51191 2.7 8.5 0.3 0.5 16.795 0.0006 HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
73 8347 9.9 10.3 0.1 0.1 5.381 0.0101 HIST1H2BC histone cluster 1, H2bc
74 8348 12.5 12.8 0.1 0.1 3.462 0.0406 HIST1H2BO histone cluster 1, H2bo
75 8346 11.8 12.1 0.2 0.2 1.530 0.2108 HIST1H2BI histone cluster 1, H2bi
76 3659 5.6 7.4 0.7 0.7 3.171 0.0340 IRF1 interferon regulatory factor 1
77 2119 2.3 2.3 0.0 0.1 -0.797 0.4958 ETV5 ets variant 5
78 7128 2.8 4.6 0.8 0.7 2.943 0.0434 TNFAIP3 tumor necrosis factor, alpha-induced protein 3
79 1195 9.2 9.0 0.4 0.3 -0.771 0.4890 CLK1 CDC-like kinase 1
80 23321 7.4 8.0 0.1 0.2 5.503 0.0193 TRIM2 tripartite motif containing 2
81 6307 5.7 7.2 0.2 0.6 4.371 0.0371 MSMO1 methylsterol monooxygenase 1
82 54800 8.8 7.1 0.3 1.1 -2.543 0.1103 KLHL24 kelch-like family member 24
83 25976 7.1 7.0 0.3 0.1 -0.145 0.8951 TIPARP TCDD-inducible poly(ADP-ribose) polymerase
84 1827 8.3 7.6 0.5 0.1 -2.654 0.0978 RCAN1 regulator of calcineurin 1
85 2354 4.6 4.0 0.6 1.1 -0.740 0.5113 FOSB FBJ murine osteosarcoma viral oncogene homolog B
86 55601 5.1 9.5 1.3 1.3 4.116 0.0147 DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
87 8795 12.2 12.1 0.4 0.8 -0.292 0.7895 TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
88 901 6.3 5.7 0.7 0.3 -1.514 0.2416 CCNG2 cyclin G2
89 10628 15.0 15.3 0.3 1.0 0.531 0.6420 TXNIP thioredoxin interacting protein
90 374 6.2 12.7 0.4 0.9 12.056 0.0017 AREG amphiregulin
91 4189 10.2 12.3 0.2 0.8 4.455 0.0342 DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
92 65986 6.1 7.3 0.5 0.2 3.574 0.0481 ZBTB10 zinc finger and BTB domain containing 10
93 694 10.6 9.8 0.1 0.6 -2.225 0.1537 BTG1 B-cell translocation gene 1, anti-proliferative
94 1839 3.0 4.5 0.7 0.5 2.901 0.0461 HBEGF heparin-binding EGF-like growth factor
95 8061 4.5 4.3 0.5 0.2 -0.643 0.5695 FOSL1 FOS-like antigen 1
96 3383 5.9 5.3 0.9 0.1 -1.060 0.3965 ICAM1 intercellular adhesion molecule 1
97 1847 8.2 6.2 0.5 0.5 -4.662 0.0097 DUSP5 dual specificity phosphatase 5
98 1846 7.6 9.1 0.3 0.5 4.351 0.0192 DUSP4 dual specificity phosphatase 4
99 1843 8.0 8.9 0.2 0.7 2.183 0.1388 DUSP1 dual specificity phosphatase 1
100 3157 9.7 10.2 0.5 0.7 0.956 0.3998 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
101 1942 10.8 10.1 0.5 0.1 -2.581 0.1047 EFNA1 ephrin-A1
102 3949 12.8 13.0 0.5 0.2 0.530 0.6406 LDLR low density lipoprotein receptor
103 4597 8.8 9.6 0.1 0.9 1.471 0.2761 MVD mevalonate (diphospho) decarboxylase
104 1543 7.8 5.2 0.8 0.3 -5.420 0.0168 CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
105 723790 11.0 10.4 0.2 0.2 -3.100 0.0362 HIST2H2AA4 histone cluster 2, H2aa4
106 50615 3.1 3.7 0.2 0.4 2.389 0.0994 IL21R interleukin 21 receptor
107 440 14.0 15.8 1.3 1.4 1.632 0.1783 ASNS asparagine synthetase (glutamine-hydrolyzing)
108 8660 8.8 9.5 0.1 1.0 1.116 0.3784 IRS2 insulin receptor substrate 2
109 23645 6.9 8.0 0.4 0.5 2.901 0.0445 PPP1R15A protein phosphatase 1, regulatory subunit 15A
110 7538 11.2 10.9 0.5 0.6 -0.641 0.5570 ZFP36 ZFP36 ring finger protein
111 3669 9.9 13.5 0.4 0.2 14.181 0.0003 ISG20 interferon stimulated exonuclease gene 20kDa
112 81558 11.4 10.2 0.1 0.8 -2.762 0.1075 FAM117A family with sequence similarity 117, member A
113 6303 7.9 9.2 0.4 0.8 2.437 0.0899 SAT1 spermidine/spermine N1-acetyltransferase 1
114 4502 15.9 17.4 0.8 0.1 3.220 0.0823 MT2A metallothionein 2A
115 1604 10.4 10.5 0.1 0.9 0.209 0.8537 CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
116 3726 7.3 7.5 0.4 0.4 0.470 0.6628 JUNB jun B proto-oncogene
117 330 2.8 5.1 1.1 0.9 2.743 0.0537 BIRC3 baculoviral IAP repeat containing 3
118 3727 9.0 9.7 0.4 0.1 2.708 0.0943 JUND jun D proto-oncogene
119 23657 7.4 12.0 2.5 1.5 2.747 0.0651 SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
120 2309 11.3 10.8 0.1 0.5 -1.829 0.1973 FOXO3 forkhead box O3
121 6662 6.0 4.4 0.1 0.3 -10.166 0.0068 SOX9 SRY (sex determining region Y)-box 9
122 80117 2.1 2.1 0.0 0.0 -2.247 0.1218 ARL14 ADP-ribosylation factor-like 14
123 8349 7.2 6.8 0.1 0.4 -1.286 0.3160 HIST2H2BE histone cluster 2, H2be
124 3012 11.7 11.1 0.2 0.1 -4.699 0.0123 HIST1H2AE histone cluster 1, H2ae
125 3013 13.5 13.1 0.1 0.2 -3.379 0.0561 HIST1H2AD histone cluster 1, H2ad
126 554313 12.3 13.1 0.2 0.1 7.087 0.0042 HIST2H4B histone cluster 2, H4b
127 12 7.2 8.4 1.1 0.9 1.443 0.2242 SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
128 8335 9.8 10.3 0.1 0.3 2.210 0.1208 HIST1H2AB histone cluster 1, H2ab
129 1051 12.8 14.6 1.0 1.3 2.040 0.1159 CEBPB CCAAT/enhancer binding protein (C/EBP), beta
130 9709 13.9 14.9 0.7 1.0 1.496 0.2148 HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
131 121504 5.7 6.1 0.2 0.5 1.193 0.3232 HIST4H4 histone cluster 4, H4
132 23175 7.9 8.7 0.2 0.2 5.303 0.0077 LPIN1 lipin 1
133 22822 4.4 3.3 0.1 0.2 -7.377 0.0059 PHLDA1 pleckstrin homology-like domain, family A, member 1
134 7071 9.3 10.3 0.2 0.9 1.810 0.2046 KLF10 Kruppel-like factor 10
135 2114 5.3 7.1 0.3 0.1 9.516 0.0042 ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
136 1316 5.6 6.0 0.6 0.1 1.110 0.3784 KLF6 Kruppel-like factor 6
137 9314 6.3 8.8 0.1 0.1 25.802 0.0000 KLF4 Kruppel-like factor 4 (gut)
138 56521 6.6 9.6 0.5 0.4 8.036 0.0016 DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
139 10365 6.8 7.3 0.3 0.7 1.172 0.3388 KLF2 Kruppel-like factor 2
140 5997 6.9 5.5 0.2 1.0 -2.284 0.1373 RGS2 regulator of G-protein signaling 2
141 51478 7.5 7.4 0.2 0.5 -0.257 0.8148 HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
142 301 2.7 5.3 0.3 0.4 9.066 0.0012 ANXA1 annexin A1
143 4929 6.0 6.8 0.1 0.0 18.498 0.0001 NR4A2 nuclear receptor subfamily 4, group A, member 2
144 8013 4.3 3.6 0.5 0.4 -1.930 0.1280 NR4A3 nuclear receptor subfamily 4, group A, member 3
145 3164 2.3 2.4 0.0 0.1 1.029 0.4036 NR4A1 nuclear receptor subfamily 4, group A, member 1
146 8638 8.9 10.3 0.1 1.4 1.759 0.2199 OASL 2'-5'-oligoadenylate synthetase-like
147 8358 13.5 13.5 0.1 0.1 0.176 0.8723 HIST1H3B histone cluster 1, H3b
148 8352 14.1 15.1 0.2 0.5 3.104 0.0742 HIST1H3C histone cluster 1, H3c
149 8350 13.6 13.1 0.2 0.2 -3.950 0.0170 HIST1H3A histone cluster 1, H3a
150 8968 12.4 12.7 0.0 0.2 2.693 0.1087 HIST1H3F histone cluster 1, H3f
151 8355 13.1 13.6 0.0 0.2 5.811 0.0203 HIST1H3G histone cluster 1, H3g
152 8351 13.7 13.9 0.0 0.2 1.524 0.2542 HIST1H3D histone cluster 1, H3d
153 8353 12.6 12.4 0.1 0.1 -1.773 0.1511 HIST1H3E histone cluster 1, H3e
154 8356 9.0 9.5 0.5 0.3 1.479 0.2258 HIST1H3J histone cluster 1, H3j
155 8357 9.7 10.0 0.1 0.1 3.279 0.0306 HIST1H3H histone cluster 1, H3h
156 8354 9.1 9.8 0.1 0.1 9.407 0.0010 HIST1H3I histone cluster 1, H3i
157 11221 5.7 5.1 0.7 0.7 -1.093 0.3359 DUSP10 dual specificity phosphatase 10
158 8878 13.2 12.9 0.4 0.1 -1.232 0.3257 SQSTM1 sequestosome 1
159 54676 8.8 9.8 0.5 0.9 1.625 0.1984 GTPBP2 GTP binding protein 2
160 51278 12.9 13.1 0.4 0.1 0.681 0.5612 IER5 immediate early response 5
161 3638 11.2 12.3 0.8 0.7 1.689 0.1670 INSIG1 insulin induced gene 1
162 9592 14.7 14.8 0.3 0.2 0.427 0.6932 IER2 immediate early response 2
163 26959 9.3 8.6 0.1 0.5 -2.532 0.1155 HBP1 HMG-box transcription factor 1
164 27289 4.1 3.5 0.9 1.1 -0.720 0.5124 RND1 Rho family GTPase 1
165 23237 11.3 7.6 0.0 0.5 -13.283 0.0056 ARC activity-regulated cytoskeleton-associated protein
166 7050 8.1 8.7 0.3 0.3 2.374 0.0787 TGIF1 TGFB-induced factor homeobox 1
167 6509 5.1 6.4 0.8 0.3 2.692 0.0910 SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
168 604 10.7 11.2 0.2 0.9 0.780 0.5119 BCL6 B-cell CLL/lymphoma 6
169 467 6.5 7.7 0.2 0.9 2.324 0.1342 ATF3 activating transcription factor 3