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BRCA1_DN.V1_UP

GeneID Mean_1 Mean_3 StDev_1 StDev_3 T-Statistic p-value SymbolDescription
1 1103 4.9 5.0 0.4 0.4 0.570 0.5992 CHAT choline O-acetyltransferase
2 8929 2.2 2.4 0.0 0.2 1.129 0.3748 PHOX2B paired-like homeobox 2b
3 9312 2.2 2.6 0.0 0.4 1.701 0.2310 KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2
4 57333 5.7 5.6 0.3 0.6 -0.412 0.7110 RCN3 reticulocalbin 3, EF-hand calcium binding domain
5 27296 3.1 3.0 0.3 0.4 -0.089 0.9340 TP53TG5 TP53 target 5
6 22829 2.6 2.3 0.5 0.0 -0.923 0.4529 NLGN4Y neuroligin 4, Y-linked
7 3965 3.7 3.7 0.2 0.1 0.213 0.8422 LGALS9 lectin, galactoside-binding, soluble, 9
8 30012 2.4 2.4 0.0 0.0 0.260 0.8132 TLX3 T-cell leukemia homeobox 3
9 79958 2.7 3.1 0.3 0.2 1.989 0.1258 DENND1C DENN/MADD domain containing 1C
10 8808 3.0 2.4 0.6 0.3 -1.332 0.2785 IL1RL2 interleukin 1 receptor-like 2
11 8287 2.6 2.5 0.3 0.1 -0.666 0.5558 USP9Y ubiquitin specific peptidase 9, Y-linked
12 79845 8.1 8.4 0.4 0.1 1.136 0.3604 RNF122 ring finger protein 122
13 8091 4.7 4.8 0.1 0.2 1.055 0.3564 HMGA2 high mobility group AT-hook 2
14 6495 10.8 10.5 0.2 0.1 -2.003 0.1589 SIX1 SIX homeobox 1
15 79781 2.6 3.1 0.1 0.9 0.889 0.4670 IQCA1 IQ motif containing with AAA domain 1
16 10942 2.8 2.6 0.6 0.5 -0.528 0.6262 PRSS21 protease, serine, 21 (testisin)
17 8552 5.7 5.3 0.1 0.8 -0.959 0.4364 INE1 inactivation escape 1 (non-protein coding)
18 9120 9.3 9.0 0.4 0.4 -0.856 0.4415 SLC16A6 solute carrier family 16, member 6
19 6770 2.7 3.1 0.3 0.1 1.998 0.1684 STAR steroidogenic acute regulatory protein
20 26468 7.9 8.3 0.5 0.8 0.783 0.4858 LHX6 LIM homeobox 6
21 79015 6.8 3.8 2.1 0.3 -2.441 0.1314 LINC01260 long intergenic non-protein coding RNA 1260
22 55224 9.7 9.3 0.2 0.1 -3.610 0.0279 ETNK2 ethanolamine kinase 2
23 7079 3.2 2.4 1.3 0.1 -1.003 0.4212 TIMP4 TIMP metallopeptidase inhibitor 4
24 438 2.4 2.3 0.1 0.0 -0.986 0.4140 ASMT acetylserotonin O-methyltransferase
25 54855 6.3 8.3 0.3 0.8 4.235 0.0342 FAM46C family with sequence similarity 46, member C
26 23562 3.4 2.4 1.6 0.1 -1.064 0.3985 CLDN14 claudin 14
27 23090 2.4 2.4 0.0 0.1 0.292 0.7878 ZNF423 zinc finger protein 423
28 390999 3.5 4.7 0.4 2.6 0.844 0.4835 PRAMEF12 PRAME family member 12
29 10536 11.1 11.5 0.3 0.2 2.110 0.1044 LEPREL2 leprecan-like 2
30 9103 2.5 2.6 0.2 0.2 0.247 0.8182 FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
31 8989 2.8 2.6 0.3 0.1 -0.924 0.4372 TRPA1 transient receptor potential cation channel, subfamily A, member 1
32 2830 2.4 3.3 0.1 1.5 1.027 0.4120 GPR6 G protein-coupled receptor 6
33 54913 7.0 7.3 0.2 0.0 2.063 0.1696 RPP25 ribonuclease P/MRP 25kDa subunit
34 1421 3.1 3.1 0.3 0.4 0.114 0.9156 CRYGD crystallin, gamma D
35 887 3.3 2.6 1.3 0.2 -0.945 0.4413 CCKBR cholecystokinin B receptor
36 9447 2.5 3.3 0.3 1.7 0.771 0.5177 AIM2 absent in melanoma 2
37 79739 4.9 4.1 0.4 0.7 -1.872 0.1476 TTLL7 tubulin tyrosine ligase-like family member 7
38 79999 5.7 4.7 0.7 0.5 -1.993 0.1222 LOC79999 uncharacterized LOC79999
39 915 4.4 4.6 0.4 0.7 0.446 0.6850 CD3D CD3d molecule, delta (CD3-TCR complex)
40 79846 4.1 3.4 2.5 1.0 -0.439 0.6945 CFAP69 cilia and flagella associated protein 69
41 8501 7.1 6.2 1.2 0.5 -1.213 0.3259 SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
42 79446 5.6 5.6 0.4 0.2 -0.025 0.9820 WDR25 WD repeat domain 25
43 23498 3.4 4.3 0.4 0.5 2.328 0.0823 HAAO 3-hydroxyanthranilate 3,4-dioxygenase
44 11202 3.6 7.0 1.0 0.1 5.839 0.0265 KLK8 kallikrein-related peptidase 8
45 322 4.7 4.4 0.3 0.2 -1.431 0.2403 APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
46 27255 3.6 3.9 0.2 0.5 0.809 0.4838 CNTN6 contactin 6
47 8353 12.6 12.6 0.1 0.0 -0.599 0.5954 HIST1H3E histone cluster 1, H3e
48 7409 10.2 9.4 0.0 0.3 -4.310 0.0469 VAV1 vav 1 guanine nucleotide exchange factor
49 4056 7.1 7.0 0.3 0.3 -0.132 0.9013 LTC4S leukotriene C4 synthase
50 91120 6.9 6.5 0.2 0.1 -3.618 0.0256 ZNF682 zinc finger protein 682
51 29119 3.1 2.4 0.1 0.1 -8.039 0.0013 CTNNA3 catenin (cadherin-associated protein), alpha 3
52 123872 2.6 3.2 0.1 1.0 0.970 0.4311 DNAAF1 dynein, axonemal, assembly factor 1
53 6981 5.4 3.4 0.4 0.9 -3.549 0.0443 TRGV7 T cell receptor gamma variable 7 (pseudogene)
54 26045 3.0 2.4 0.4 0.3 -2.195 0.1048 LRRTM2 leucine rich repeat transmembrane neuronal 2
55 3371 3.1 3.1 0.1 0.6 0.044 0.9683 TNC tenascin C
56 163131 5.9 5.7 0.3 0.4 -0.792 0.4751 ZNF780B zinc finger protein 780B
57 4133 5.0 4.8 0.6 0.2 -0.607 0.5958 MAP2 microtubule-associated protein 2
58 3653 3.8 2.8 0.3 0.1 -5.931 0.0232 IPW imprinted in Prader-Willi syndrome (non-protein coding)
59 10850 4.2 4.5 0.3 0.5 0.682 0.5427 CCL27 chemokine (C-C motif) ligand 27
60 5802 9.5 9.4 0.1 0.2 -0.469 0.6738 PTPRS protein tyrosine phosphatase, receptor type, S
61 55843 2.2 2.5 0.0 0.4 1.060 0.4002 ARHGAP15 Rho GTPase activating protein 15
62 58158 2.1 2.1 0.0 0.0 0.580 0.5949 NEUROD4 neuronal differentiation 4
63 54766 2.3 2.3 0.0 0.0 0.018 0.9864 BTG4 B-cell translocation gene 4
64 23617 3.4 2.3 1.4 0.0 -1.329 0.3152 TSSK2 testis-specific serine kinase 2
65 6013 6.9 5.2 0.3 0.2 -8.033 0.0034 RLN1 relaxin 1
66 50944 2.5 2.7 0.2 0.3 0.816 0.4711 SHANK1 SH3 and multiple ankyrin repeat domains 1
67 11039 10.2 10.3 0.0 0.2 1.044 0.4037 SMA4 glucuronidase, beta pseudogene
68 6579 2.5 2.7 0.1 0.3 1.041 0.3934 SLCO1A2 solute carrier organic anion transporter family, member 1A2
69 51378 3.5 3.5 0.4 0.9 0.091 0.9335 ANGPT4 angiopoietin 4
70 2134 5.9 4.0 0.2 0.5 -6.541 0.0139 EXTL1 exostosin-like glycosyltransferase 1
71 947 2.6 2.4 0.1 0.1 -2.834 0.0480 CD34 CD34 molecule
72 57711 8.3 8.3 0.1 0.3 0.483 0.6613 ZNF529 zinc finger protein 529
73 3448 2.2 2.4 0.0 0.2 1.130 0.3753 IFNA14 interferon, alpha 14
74 3773 2.6 2.3 0.5 0.0 -0.918 0.4545 KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
75 399 6.0 6.8 0.2 0.6 2.196 0.1379 RHOH ras homolog family member H
76 116828 6.2 5.6 0.3 0.2 -2.522 0.0816 N4BP2L2-IT2 N4BPL2 intronic transcript 2 (non-protein coding)
77 1493 2.6 2.7 0.2 0.6 0.346 0.7563 CTLA4 cytotoxic T-lymphocyte-associated protein 4
78 350 2.8 2.7 0.8 0.8 -0.034 0.9742 APOH apolipoprotein H (beta-2-glycoprotein I)
79 9079 3.3 3.1 0.6 0.2 -0.667 0.5597 LDB2 LIM domain binding 2
80 7066 3.6 3.3 0.4 0.5 -0.597 0.5828 THPO thrombopoietin
81 2560 3.1 3.0 0.2 0.1 -0.916 0.4140 GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
82 84719 5.8 5.9 0.3 0.2 0.323 0.7642 LINC00260 long intergenic non-protein coding RNA 260
83 57408 2.8 2.8 0.2 0.3 0.196 0.8563 LRTM1 leucine-rich repeats and transmembrane domains 1
84 55503 5.4 2.8 0.1 0.0 -35.632 0.0005 TRPV6 transient receptor potential cation channel, subfamily V, member 6
85 3217 4.6 5.5 0.5 0.2 3.034 0.0748 HOXB7 homeobox B7
86 2765 3.8 3.4 0.7 0.5 -0.659 0.5495 GML glycosylphosphatidylinositol anchored molecule like
87 55025 2.3 2.3 0.0 0.0 0.068 0.9491 FLJ20712 uncharacterized FLJ20712
88 747 5.7 3.1 4.1 0.3 -1.086 0.3900 DAGLA diacylglycerol lipase, alpha
89 90134 2.3 2.4 0.0 0.0 0.984 0.3811 KCNH7 potassium channel, voltage gated eag related subfamily H, member 7
90 116039 9.1 8.3 0.1 0.3 -4.797 0.0177 OSR2 odd-skipped related transciption factor 2
91 79054 3.4 3.8 0.9 1.7 0.363 0.7408 TRPM8 transient receptor potential cation channel, subfamily M, member 8
92 5897 3.1 3.1 0.6 0.7 0.046 0.9657 RAG2 recombination activating gene 2
93 3567 3.3 3.3 0.1 0.9 0.064 0.9547 IL5 interleukin 5
94 4821 3.2 2.7 1.0 0.7 -0.842 0.4520 NKX2-2 NK2 homeobox 2
95 23626 2.2 2.7 0.0 0.8 1.004 0.4212 SPO11 SPO11 meiotic protein covalently bound to DSB
96 6870 2.3 2.3 0.0 0.1 0.057 0.9584 TACR3 tachykinin receptor 3
97 6442 4.1 3.6 0.5 0.4 -1.360 0.2481 SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
98 283212 9.1 9.2 0.0 0.2 0.872 0.4676 KLHL35 kelch-like family member 35
99 64581 2.4 2.2 0.2 0.0 -0.994 0.4243 CLEC7A C-type lectin domain family 7, member A
100 55613 2.5 2.5 0.0 0.0 -0.306 0.7775 MTMR8 myotubularin related protein 8
101 1044 5.1 4.9 0.1 0.0 -2.383 0.1265 CDX1 caudal type homeobox 1
102 79166 3.0 2.4 0.5 0.0 -2.054 0.1756 LILRP2 leukocyte immunoglobulin-like receptor pseudogene 2
103 8483 4.4 4.3 1.0 0.5 -0.094 0.9308 CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
104 29118 2.5 2.3 0.4 0.0 -0.957 0.4383 DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25
105 4604 2.6 2.8 0.3 0.3 0.938 0.4014 MYBPC1 myosin binding protein C, slow type
106 6792 8.4 7.9 0.3 0.4 -1.910 0.1313 CDKL5 cyclin-dependent kinase-like 5
107 8857 6.4 6.9 0.6 0.8 0.971 0.3895 FCGBP Fc fragment of IgG binding protein
108 8707 2.4 2.4 0.1 0.1 0.165 0.8773 B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
109 8973 3.3 3.4 0.4 0.1 0.538 0.6427 CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
110 5568 2.3 3.5 0.1 1.7 1.253 0.3356 PRKACG protein kinase, cAMP-dependent, catalytic, gamma
111 26038 3.8 3.9 0.2 0.1 0.269 0.8016 CHD5 chromodomain helicase DNA binding protein 5
112 113612 6.6 7.1 0.3 0.0 2.892 0.0971 CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
113 5304 7.9 2.9 1.5 0.8 -5.177 0.0145 PIP prolactin-induced protein
114 4033 2.3 2.3 0.0 0.0 -0.803 0.4732 LRMP lymphoid-restricted membrane protein
115 1240 2.6 2.7 0.2 0.3 0.591 0.5938 CMKLR1 chemokine-like receptor 1
116 7058 3.0 2.5 0.8 0.1 -1.123 0.3750 THBS2 thrombospondin 2
117 3605 2.4 2.3 0.3 0.0 -1.012 0.4169 IL17A interleukin 17A
118 11126 2.8 2.9 0.5 0.4 0.301 0.7790 CD160 CD160 molecule
119 7827 4.5 5.1 0.5 0.4 1.488 0.2174 NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
120 2702 2.5 2.6 0.1 0.3 0.798 0.5049 GJA5 gap junction protein, alpha 5, 40kDa
121 51477 10.7 10.2 0.2 0.1 -4.309 0.0207 ISYNA1 inositol-3-phosphate synthase 1
122 1012 2.5 2.5 0.1 0.1 0.021 0.9844 CDH13 cadherin 13
123 7348 2.3 2.3 0.0 0.0 0.270 0.8007 UPK1B uroplakin 1B
124 3737 2.6 2.7 0.1 0.2 0.443 0.6843 KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
125 6671 6.9 7.0 0.3 0.1 0.898 0.4598 SP4 Sp4 transcription factor
126 9122 6.3 6.6 0.4 0.2 1.239 0.3044 SLC16A4 solute carrier family 16, member 4
127 1618 2.5 2.5 0.1 0.1 0.226 0.8348 DAZL deleted in azoospermia-like
128 9074 3.5 2.3 1.1 0.0 -1.875 0.2015 CLDN6 claudin 6
129 8970 10.2 10.3 0.1 0.2 0.330 0.7631 HIST1H2BJ histone cluster 1, H2bj
130 64405 11.5 11.5 0.1 0.2 0.090 0.9339 CDH22 cadherin 22, type 2
131 5047 4.1 4.6 0.2 0.8 1.094 0.3799 PAEP progestagen-associated endometrial protein
132 25833 4.6 4.5 0.3 0.4 -0.467 0.6653 POU2F3 POU class 2 homeobox 3
133 57152 8.3 7.3 0.1 0.1 -8.112 0.0014 SLURP1 secreted LY6/PLAUR domain containing 1
134 63974 2.6 2.6 0.0 0.1 0.147 0.8925 NEUROD6 neuronal differentiation 6
135 2895 3.7 3.2 0.4 0.6 -1.220 0.3009 GRID2 glutamate receptor, ionotropic, delta 2