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AKT_UP.V1_DN

GeneID Mean_1 Mean_3 StDev_1 StDev_3 T-Statistic p-value SymbolDescription
1 3777 3.6 3.8 0.3 1.1 0.186 0.8677 KCNK3 potassium channel, two pore domain subfamily K, member 3
2 27232 5.5 6.1 1.2 0.4 0.810 0.4922 GNMT glycine N-methyltransferase
3 3381 2.4 3.2 0.0 0.7 1.865 0.2029 IBSP integrin-binding sialoprotein
4 362 6.0 6.0 0.1 0.1 0.432 0.6925 AQP5 aquaporin 5
5 8140 12.6 13.8 0.5 0.2 3.826 0.0367 SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
6 10954 9.3 9.8 0.1 0.1 5.753 0.0046 PDIA5 protein disulfide isomerase family A, member 5
7 3783 6.3 9.1 0.5 0.4 7.460 0.0018 KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
8 445 12.9 13.1 0.5 0.0 0.535 0.6454 ASS1 argininosuccinate synthase 1
9 57124 2.7 3.0 0.7 0.7 0.400 0.7096 CD248 CD248 molecule, endosialin
10 28232 2.4 6.0 0.2 0.2 20.898 0.0000 SLCO3A1 solute carrier organic anion transporter family, member 3A1
11 6604 12.0 10.5 0.3 0.3 -6.346 0.0035 SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
12 23328 4.9 4.1 0.2 0.4 -2.607 0.0736 SASH1 SAM and SH3 domain containing 1
13 8842 3.8 2.6 0.7 0.2 -2.953 0.0863 PROM1 prominin 1
14 5507 10.5 9.4 0.4 0.5 -3.256 0.0326 PPP1R3C protein phosphatase 1, regulatory subunit 3C
15 221476 3.4 3.6 0.3 0.7 0.394 0.7244 PI16 peptidase inhibitor 16
16 5348 3.7 3.9 0.4 0.1 0.803 0.5031 FXYD1 FXYD domain containing ion transport regulator 1
17 56975 7.6 7.7 0.3 0.3 0.338 0.7530 FAM20C family with sequence similarity 20, member C
18 5317 3.3 4.4 0.3 0.5 3.795 0.0300 PKP1 plakophilin 1
19 6450 9.1 8.6 0.2 0.2 -2.788 0.0495 SH3BGR SH3 domain binding glutamate-rich protein
20 7125 7.9 6.2 0.0 0.2 -18.455 0.0014 TNNC2 troponin C type 2 (fast)
21 84818 8.0 8.1 0.5 0.2 0.086 0.9379 IL17RC interleukin 17 receptor C
22 6199 14.2 14.0 0.1 0.1 -3.534 0.0321 RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
23 116085 2.8 3.4 0.5 0.5 1.596 0.1866 SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12
24 7106 11.2 11.3 0.1 0.1 0.300 0.7789 TSPAN4 tetraspanin 4
25 8476 8.4 8.4 0.1 0.0 0.691 0.5509 CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
26 2202 13.2 12.0 0.0 0.3 -8.107 0.0137 EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
27 55501 11.0 10.6 0.4 0.2 -1.362 0.2824 CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
28 858 3.3 4.2 0.1 0.9 1.734 0.2197 CAV2 caveolin 2
29 715 6.5 7.6 0.8 0.1 2.365 0.1356 C1R complement component 1, r subcomponent
30 647087 10.3 11.2 0.2 0.2 4.916 0.0082 C7orf73 chromosome 7 open reading frame 73
31 5654 10.8 11.1 0.6 0.0 1.106 0.3825 HTRA1 HtrA serine peptidase 1
32 2328 2.3 2.3 0.0 0.0 -0.469 0.6650 FMO3 flavin containing monooxygenase 3
33 6586 3.9 4.7 0.3 0.2 4.212 0.0186 SLIT3 slit homolog 3 (Drosophila)
34 1903 7.4 11.1 0.3 0.4 13.221 0.0003 S1PR3 sphingosine-1-phosphate receptor 3
35 57007 14.2 11.0 0.1 0.4 -13.543 0.0042 ACKR3 atypical chemokine receptor 3
36 166785 6.6 6.5 0.2 0.2 -0.595 0.5840 MMAA methylmalonic aciduria (cobalamin deficiency) cblA type
37 115207 7.0 6.6 0.3 0.3 -1.476 0.2144 KCTD12 potassium channel tetramerization domain containing 12
38 3866 10.4 9.0 0.3 0.4 -4.676 0.0140 KRT15 keratin 15, type I
39 10267 12.5 11.6 0.2 0.1 -6.798 0.0145 RAMP1 receptor (G protein-coupled) activity modifying protein 1
40 57459 8.0 7.4 0.2 0.1 -4.385 0.0173 GATAD2B GATA zinc finger domain containing 2B
41 55167 8.7 8.8 0.2 0.1 1.310 0.2768 MSL2 male-specific lethal 2 homolog (Drosophila)
42 4811 2.4 2.2 0.4 0.0 -1.003 0.4212 NID1 nidogen 1
43 6570 2.4 2.4 0.1 0.1 0.345 0.7494 SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
44 137872 4.1 3.4 0.4 0.9 -1.276 0.2940 ADHFE1 alcohol dehydrogenase, iron containing, 1
45 7760 9.5 8.9 0.2 0.1 -5.156 0.0078 ZNF213 zinc finger protein 213
46 80760 2.5 2.5 0.1 0.1 0.202 0.8497 ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
47 6257 9.0 8.4 0.4 0.1 -2.531 0.1090 RXRB retinoid X receptor, beta
48 11201 9.3 9.5 0.2 0.2 1.176 0.3050 POLI polymerase (DNA directed) iota
49 30008 8.6 7.6 0.1 1.2 -1.433 0.2872 EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
50 56955 2.5 3.0 0.3 0.9 1.034 0.3934 MEPE matrix extracellular phosphoglycoprotein
51 6783 2.7 2.8 0.5 0.7 0.252 0.8146 SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
52 2100 2.8 2.7 0.4 0.7 -0.164 0.8798 ESR2 estrogen receptor 2 (ER beta)
53 2941 6.0 7.0 0.5 0.2 3.238 0.0582 GSTA4 glutathione S-transferase alpha 4
54 22921 10.5 11.3 0.1 0.1 8.035 0.0023 MSRB2 methionine sulfoxide reductase B2
55 5407 3.9 3.7 0.1 0.2 -1.425 0.2356 PNLIPRP1 pancreatic lipase-related protein 1
56 1124 2.8 2.6 0.4 0.2 -0.691 0.5398 CHN2 chimerin 2
57 8013 4.3 3.4 0.5 0.7 -1.742 0.1642 NR4A3 nuclear receptor subfamily 4, group A, member 3
58 3707 7.8 6.7 0.3 0.5 -3.245 0.0466 ITPKB inositol-trisphosphate 3-kinase B
59 1805 5.4 5.6 0.1 0.1 2.209 0.1105 DPT dermatopontin
60 51435 8.8 8.4 0.3 0.2 -2.079 0.1281 SCARA3 scavenger receptor class A, member 3
61 5345 3.1 2.5 0.6 0.3 -1.429 0.2594 SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
62 617 11.4 11.3 0.3 0.1 -0.716 0.5448 BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like
63 6304 10.7 2.5 0.0 0.2 -72.118 0.0001 SATB1 SATB homeobox 1
64 23371 9.5 8.7 0.1 0.6 -2.123 0.1602 TNS2 tensin 2
65 10461 2.7 3.4 0.4 1.0 1.230 0.3198 MERTK MER proto-oncogene, tyrosine kinase
66 2184 11.7 10.7 0.1 0.1 -13.427 0.0002 FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
67 114907 10.2 9.1 0.4 1.1 -1.665 0.2089 FBXO32 F-box protein 32
68 271 10.4 9.9 0.2 0.2 -3.438 0.0305 AMPD2 adenosine monophosphate deaminase 2
69 9572 6.9 6.8 0.5 0.4 -0.387 0.7208 NR1D1 nuclear receptor subfamily 1, group D, member 1
70 150383 10.1 10.1 0.2 0.2 0.571 0.6003 CDPF1 cysteine-rich, DPF motif domain containing 1
71 51333 11.0 11.0 0.1 0.0 -1.277 0.3167 ZNF771 zinc finger protein 771
72 27254 2.2 2.3 0.0 0.2 1.046 0.4032 CSDC2 cold shock domain containing C2, RNA binding
73 51702 3.3 3.2 0.7 1.4 -0.090 0.9339 PADI3 peptidyl arginine deiminase, type III
74 23024 5.4 4.7 0.2 0.2 -4.232 0.0165 PDZRN3 PDZ domain containing ring finger 3
75 23270 10.3 9.8 0.2 0.1 -3.181 0.0496 TSPYL4 TSPY-like 4
76 51129 8.8 8.6 0.8 0.3 -0.497 0.6582 ANGPTL4 angiopoietin-like 4
77 26499 10.9 10.9 0.1 0.1 0.199 0.8551 PLEK2 pleckstrin 2
78 1308 2.2 2.2 0.0 0.0 0.242 0.8275 COL17A1 collagen, type XVII, alpha 1
79 3667 8.5 10.0 0.3 0.2 7.365 0.0043 IRS1 insulin receptor substrate 1
80 3852 2.5 2.4 0.1 0.1 -0.211 0.8439 KRT5 keratin 5, type II
81 51733 2.8 2.5 0.2 0.1 -2.742 0.0848 UPB1 ureidopropionase, beta
82 1101 4.3 4.0 1.3 0.5 -0.400 0.7211 CHAD chondroadherin
83 716 3.4 3.8 0.5 0.2 1.516 0.2263 C1S complement component 1, s subcomponent
84 645 14.4 14.5 0.3 0.1 0.584 0.6036 BLVRB biliverdin reductase B
85 5321 2.6 2.4 0.2 0.1 -1.285 0.3108 PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
86 57452 8.9 9.0 0.2 0.1 1.636 0.2158 GALNT16 polypeptide N-acetylgalactosaminyltransferase 16
87 1265 12.2 12.2 0.2 0.1 -0.350 0.7439 CNN2 calponin 2
88 5740 2.4 2.4 0.0 0.1 -0.073 0.9460 PTGIS prostaglandin I2 (prostacyclin) synthase
89 9027 2.4 2.4 0.0 0.0 0.398 0.7125 NAT8 N-acetyltransferase 8 (GCN5-related, putative)
90 64968 12.1 12.3 0.1 0.2 1.959 0.1219 MRPS6 mitochondrial ribosomal protein S6
91 5152 7.2 7.1 0.3 0.1 -0.472 0.6747 PDE9A phosphodiesterase 9A
92 8660 8.8 10.0 0.1 0.7 2.938 0.0938 IRS2 insulin receptor substrate 2
93 317649 7.1 6.7 0.5 0.0 -1.702 0.2302 EIF4E3 eukaryotic translation initiation factor 4E family member 3
94 6242 10.0 9.5 0.1 0.0 -6.729 0.0122 RTKN rhotekin
95 8994 6.9 6.9 0.1 0.1 0.030 0.9773 LIMD1 LIM domains containing 1
96 286133 5.5 3.5 0.2 0.2 -12.132 0.0003 SCARA5 scavenger receptor class A, member 5
97 56271 4.8 2.9 0.3 0.7 -4.234 0.0289 BEX4 brain expressed, X-linked 4
98 9986 8.4 8.7 0.1 0.2 2.330 0.0914 RCE1 Ras converting CAAX endopeptidase 1
99 54517 12.1 12.9 0.2 0.2 5.602 0.0051 PUS7 pseudouridylate synthase 7 (putative)
100 50865 15.8 12.5 0.1 0.4 -14.999 0.0038 HEBP1 heme binding protein 1
101 147912 11.3 11.5 0.2 0.4 0.969 0.4143 SIX5 SIX homeobox 5
102 4969 2.4 2.6 0.0 0.5 0.913 0.4568 OGN osteoglycin
103 54494 10.3 9.8 0.1 0.2 -4.442 0.0178 C11orf71 chromosome 11 open reading frame 71
104 22859 11.0 11.0 0.1 0.0 -0.997 0.4100 LPHN1 latrophilin 1
105 4147 10.3 6.4 0.3 0.3 -17.324 0.0001 MATN2 matrilin 2
106 7741 8.3 8.4 0.2 0.1 0.703 0.5226 ZSCAN26 zinc finger and SCAN domain containing 26
107 79038 13.9 13.8 0.1 0.1 -1.371 0.2560 ZFYVE21 zinc finger, FYVE domain containing 21
108 55504 4.5 4.5 0.1 0.2 0.194 0.8555 TNFRSF19 tumor necrosis factor receptor superfamily, member 19
109 80206 7.9 4.9 0.1 0.6 -9.236 0.0108 FHOD3 formin homology 2 domain containing 3
110 3090 3.0 2.8 0.6 0.3 -0.449 0.6839 HIC1 hypermethylated in cancer 1
111 23410 9.0 8.2 0.1 0.1 -8.199 0.0026 SIRT3 sirtuin 3
112 55253 8.2 8.8 0.1 0.1 7.464 0.0020 TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
113 285966 3.9 4.2 0.2 0.3 1.328 0.2600 TCAF2 TRPM8 channel-associated factor 2
114 1014 2.8 3.2 0.4 0.5 1.031 0.3608 CDH16 cadherin 16, KSP-cadherin
115 9630 5.2 2.8 0.3 0.4 -8.335 0.0019 GNA14 guanine nucleotide binding protein (G protein), alpha 14
116 25946 11.8 11.6 0.3 0.1 -1.276 0.2989 ZNF385A zinc finger protein 385A
117 55005 11.6 10.1 0.1 0.3 -8.996 0.0055 RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
118 8434 2.4 3.0 0.0 0.3 3.565 0.0671 RECK reversion-inducing-cysteine-rich protein with kazal motifs
119 6423 2.5 2.7 0.3 0.4 0.433 0.6897 SFRP2 secreted frizzled-related protein 2
120 6943 2.5 2.4 0.2 0.0 -1.000 0.4196 TCF21 transcription factor 21
121 2542 11.2 11.5 0.1 0.1 2.537 0.0713 SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
122 51303 12.5 13.4 0.1 0.1 10.519 0.0007 FKBP11 FK506 binding protein 11, 19 kDa
123 3671 5.1 4.7 0.3 0.2 -2.308 0.0915 ISLR immunoglobulin superfamily containing leucine-rich repeat
124 51097 12.7 12.2 0.3 0.0 -3.071 0.0868 SCCPDH saccharopine dehydrogenase (putative)
125 6776 3.4 2.9 1.4 0.6 -0.636 0.5748 STAT5A signal transducer and activator of transcription 5A
126 4056 7.1 7.0 0.3 0.3 -0.132 0.9013 LTC4S leukotriene C4 synthase
127 3399 10.9 10.8 0.3 0.2 -0.248 0.8167 ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
128 3257 9.0 9.4 0.1 0.1 4.015 0.0161 HPS1 Hermansky-Pudlak syndrome 1
129 11197 2.2 2.8 0.1 1.2 0.950 0.4419 WIF1 WNT inhibitory factor 1
130 2619 3.2 3.9 1.0 1.2 0.801 0.4701 GAS1 growth arrest-specific 1
131 4653 3.0 2.7 1.4 0.9 -0.310 0.7748 MYOC myocilin, trabecular meshwork inducible glucocorticoid response
132 25842 6.0 6.3 0.2 0.1 2.243 0.1026 ASF1A anti-silencing function 1A histone chaperone
133 3158 7.8 2.3 0.5 0.0 -19.906 0.0024 HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
134 284612 2.4 2.8 0.2 0.2 2.192 0.0983 SYPL2 synaptophysin-like 2
135 8613 7.7 9.0 0.0 0.2 10.079 0.0074 PPAP2B phosphatidic acid phosphatase type 2B
136 9093 12.7 12.3 0.3 0.2 -2.032 0.1298 DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
137 55034 10.0 9.3 0.3 0.1 -4.533 0.0224 MOCOS molybdenum cofactor sulfurase
138 875 15.9 14.2 0.3 0.1 -8.434 0.0104 CBS cystathionine-beta-synthase
139 27295 4.4 7.8 0.5 0.5 8.839 0.0009 PDLIM3 PDZ and LIM domain 3
140 7078 2.4 7.1 0.2 0.9 8.696 0.0100 TIMP3 TIMP metallopeptidase inhibitor 3
141 92565 5.4 6.6 0.3 0.4 4.566 0.0141 FANK1 fibronectin type III and ankyrin repeat domains 1
142 6935 2.4 3.0 0.0 0.2 4.349 0.0423 ZEB1 zinc finger E-box binding homeobox 1
143 5425 10.5 10.6 0.1 0.1 1.081 0.3490 POLD2 polymerase (DNA directed), delta 2, accessory subunit
144 2327 3.0 2.3 1.1 0.0 -1.011 0.4180 FMO2 flavin containing monooxygenase 2 (non-functional)
145 7866 12.3 11.8 0.1 0.1 -8.658 0.0015 IFRD2 interferon-related developmental regulator 2
146 85463 2.4 2.4 0.0 0.0 0.337 0.7572 ZC3H12C zinc finger CCCH-type containing 12C
147 25900 4.2 3.5 0.0 0.2 -6.097 0.0241 IFFO1 intermediate filament family orphan 1
148 23584 2.2 2.4 0.0 0.2 1.186 0.3564 VSIG2 V-set and immunoglobulin domain containing 2
149 64429 8.5 9.0 0.2 0.1 4.100 0.0168 ZDHHC6 zinc finger, DHHC-type containing 6
150 90313 11.3 11.4 0.1 0.2 0.817 0.4609 TP53I13 tumor protein p53 inducible protein 13
151 10365 6.8 8.0 0.3 0.4 4.538 0.0137 KLF2 Kruppel-like factor 2
152 57818 2.7 2.9 0.9 1.3 0.269 0.8027 G6PC2 glucose-6-phosphatase, catalytic, 2
153 641638 14.8 13.6 0.2 0.2 -7.938 0.0015 SNHG6 small nucleolar RNA host gene 6 (non-protein coding)
154 55332 10.9 10.8 0.2 0.5 -0.453 0.6878 DRAM1 DNA-damage regulated autophagy modulator 1
155 84750 6.6 6.1 0.2 0.3 -2.701 0.0771 FUT10 fucosyltransferase 10 (alpha (1,3) fucosyltransferase)
156 51559 6.1 7.2 0.4 0.6 2.454 0.0807 NT5DC3 5'-nucleotidase domain containing 3
157 6929 13.5 13.9 0.1 0.1 4.891 0.0152 TCF3 transcription factor 3
158 64320 8.7 8.6 0.3 0.2 -0.586 0.5922 RNF25 ring finger protein 25
159 51013 12.6 12.7 0.1 0.1 1.912 0.1560 EXOSC1 exosome component 1
160 355 6.5 4.8 0.4 0.2 -7.199 0.0072 FAS Fas cell surface death receptor
161 79657 8.6 9.1 0.0 0.4 2.287 0.1465 RPAP3 RNA polymerase II associated protein 3
162 1990 2.6 2.7 0.3 0.1 0.225 0.8399 CELA1 chymotrypsin-like elastase family, member 1
163 148811 3.2 2.3 1.7 0.0 -0.985 0.4283 PM20D1 peptidase M20 domain containing 1
164 5360 6.3 5.0 0.6 0.2 -3.296 0.0650 PLTP phospholipid transfer protein
165 3597 9.8 10.3 0.1 0.1 6.928 0.0041 IL13RA1 interleukin 13 receptor, alpha 1
166 5142 4.3 6.9 1.5 0.2 3.108 0.0865 PDE4B phosphodiesterase 4B, cAMP-specific
167 10486 8.1 9.3 0.1 0.3 6.920 0.0072 CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
168 249 3.4 3.1 0.6 0.6 -0.582 0.5921 ALPL alkaline phosphatase, liver/bone/kidney
169 164091 4.5 4.5 0.5 0.2 -0.122 0.9107 PAQR7 progestin and adipoQ receptor family member VII
170 7289 11.2 11.0 0.3 0.1 -1.348 0.2978 TULP3 tubby like protein 3
171 55630 15.0 14.7 0.1 0.1 -2.792 0.0692 SLC39A4 solute carrier family 39 (zinc transporter), member 4
172 4684 2.4 2.4 0.1 0.2 -0.015 0.9884 NCAM1 neural cell adhesion molecule 1
173 2690 8.3 5.1 0.1 0.3 -16.019 0.0010 GHR growth hormone receptor
174 6097 11.3 8.8 0.1 0.4 -9.038 0.0068 RORC RAR-related orphan receptor C
175 5252 9.1 9.1 0.3 0.2 -0.107 0.9199 PHF1 PHD finger protein 1
176 128178 12.7 13.1 0.3 0.2 1.668 0.1850 EDARADD EDAR-associated death domain
177 23708 2.3 2.3 0.0 0.0 0.811 0.4762 GSPT2 G1 to S phase transition 2
178 8572 2.2 3.2 0.0 1.6 0.999 0.4229 PDLIM4 PDZ and LIM domain 4
179 8313 5.0 4.4 0.3 0.5 -2.047 0.1227 AXIN2 axin 2
180 2530 12.1 11.6 0.2 0.3 -2.219 0.0932 FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
181 9358 2.6 2.6 0.4 0.3 -0.088 0.9347 ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
182 4023 2.4 2.5 0.0 0.1 0.418 0.7059 LPL lipoprotein lipase
183 55643 10.6 10.6 0.2 0.2 0.147 0.8909 BTBD2 BTB (POZ) domain containing 2
184 7164 13.5 13.2 0.1 0.1 -2.866 0.0694 TPD52L1 tumor protein D52-like 1
185 91252 13.2 12.6 0.1 0.2 -3.743 0.0266 SLC39A13 solute carrier family 39 (zinc transporter), member 13
186 57655 7.0 6.6 0.7 0.2 -1.090 0.3735 GRAMD1A GRAM domain containing 1A
187 5156 2.3 2.3 0.0 0.0 0.365 0.7443 PDGFRA platelet-derived growth factor receptor, alpha polypeptide