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KRAS.LUNG.BREAST_UP.V1_DN

GeneID Mean_1 Mean_3 StDev_1 StDev_3 T-Statistic p-value SymbolDescription
1 8581 4.9 7.3 0.8 0.5 4.433 0.0162 LY6D lymphocyte antigen 6 complex, locus D
2 3860 4.9 3.7 0.3 0.2 -5.729 0.0082 KRT13 keratin 13, type I
3 23031 8.4 8.3 0.3 0.1 -0.369 0.7393 MAST3 microtubule associated serine/threonine kinase 3
4 1954 10.8 10.4 0.8 0.4 -0.671 0.5503 MEGF8 multiple EGF-like-domains 8
5 525 5.0 5.8 0.4 0.1 3.418 0.0652 ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
6 6278 3.5 4.7 0.2 0.8 2.459 0.1163 S100A7 S100 calcium binding protein A7
7 7104 2.7 2.7 0.4 0.5 0.094 0.9299 TM4SF4 transmembrane 4 L six family member 4
8 2053 10.8 9.4 0.1 0.6 -4.199 0.0484 EPHX2 epoxide hydrolase 2, cytoplasmic
9 51806 7.9 10.0 0.1 1.0 3.685 0.0656 CALML5 calmodulin-like 5
10 79953 3.4 4.6 0.6 0.1 3.184 0.0827 SYNDIG1 synapse differentiation inducing 1
11 5158 7.0 5.7 0.1 0.8 -2.922 0.0966 PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
12 3713 3.2 3.4 0.3 0.4 0.851 0.4466 IVL involucrin
13 6712 8.9 8.7 0.2 0.0 -1.988 0.1666 SPTBN2 spectrin, beta, non-erythrocytic 2
14 5023 2.5 2.4 0.2 0.2 -0.539 0.6204 P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
15 79097 3.1 2.9 0.8 0.4 -0.405 0.7140 TRIM48 tripartite motif containing 48
16 1010 2.7 4.8 0.6 0.3 5.484 0.0128 CDH12 cadherin 12, type 2 (N-cadherin 2)
17 57016 2.3 6.5 0.0 0.1 103.213 0.0000 AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
18 7137 5.2 6.0 0.2 0.3 3.948 0.0193 TNNI3 troponin I type 3 (cardiac)
19 10249 2.5 2.6 0.2 0.2 0.787 0.4771 GLYAT glycine-N-acyltransferase
20 338 2.6 2.4 0.2 0.0 -1.943 0.1863 APOB apolipoprotein B
21 5275 2.3 2.3 0.0 0.0 0.065 0.9510 SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
22 3851 3.8 4.5 0.6 0.1 1.982 0.1810 KRT4 keratin 4, type II
23 10398 3.6 3.5 0.5 0.3 -0.303 0.7821 MYL9 myosin, light chain 9, regulatory
24 79400 5.0 5.8 0.6 0.2 2.285 0.1241 NOX5 NADPH oxidase, EF-hand calcium binding domain 5
25 80761 8.0 5.5 0.1 0.1 -34.302 0.0000 UPK3B uroplakin 3B
26 6519 2.7 2.5 0.1 0.2 -1.141 0.3344 SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
27 55610 6.3 6.8 0.2 0.1 4.951 0.0222 CCDC132 coiled-coil domain containing 132
28 10268 2.7 2.6 0.2 0.1 -0.540 0.6188 RAMP3 receptor (G protein-coupled) activity modifying protein 3
29 3868 3.3 6.0 0.7 0.6 5.243 0.0072 KRT16 keratin 16, type I
30 1838 5.5 5.8 0.3 0.3 1.327 0.2590 DTNB dystrobrevin, beta
31 25840 12.7 12.0 0.1 0.4 -2.710 0.0993 METTL7A methyltransferase like 7A
32 10912 9.7 9.5 0.2 0.3 -0.771 0.4978 GADD45G growth arrest and DNA-damage-inducible, gamma
33 169611 4.6 5.2 0.2 0.1 4.875 0.0194 OLFML2A olfactomedin-like 2A
34 54587 2.4 2.3 0.3 0.0 -1.010 0.4162 MXRA8 matrix-remodelling associated 8
35 57124 2.7 3.0 0.7 0.7 0.400 0.7096 CD248 CD248 molecule, endosialin
36 2261 9.7 6.8 0.1 0.5 -9.721 0.0096 FGFR3 fibroblast growth factor receptor 3
37 7051 7.4 7.5 0.2 0.2 0.464 0.6670 TGM1 transglutaminase 1
38 5608 8.6 4.3 0.1 0.4 -17.882 0.0010 MAP2K6 mitogen-activated protein kinase kinase 6
39 29799 6.1 5.8 0.3 0.6 -0.642 0.5657 YPEL1 yippee-like 1 (Drosophila)
40 3351 3.9 4.0 0.6 0.4 0.131 0.9025 HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
41 6664 2.3 2.8 0.1 1.0 0.900 0.4625 SOX11 SRY (sex determining region Y)-box 11
42 9547 2.8 3.3 0.6 1.0 0.741 0.5092 CXCL14 chemokine (C-X-C motif) ligand 14
43 242 4.6 5.1 0.2 0.2 2.984 0.0409 ALOX12B arachidonate 12-lipoxygenase, 12R type
44 7252 5.3 5.8 0.1 0.1 7.695 0.0042 TSHB thyroid stimulating hormone, beta
45 259197 3.2 3.3 0.2 0.2 0.241 0.8220 NCR3 natural cytotoxicity triggering receptor 3
46 25809 8.3 8.1 0.5 0.5 -0.608 0.5759 TTLL1 tubulin tyrosine ligase-like family member 1
47 5287 8.4 8.7 0.2 0.2 2.242 0.0884 PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
48 7226 2.5 3.0 0.3 0.6 1.296 0.2898 TRPM2 transient receptor potential cation channel, subfamily M, member 2
49 79148 6.5 6.7 0.2 0.2 1.082 0.3414 MMP28 matrix metallopeptidase 28
50 5139 2.4 2.3 0.4 0.2 -0.599 0.5965 PDE3A phosphodiesterase 3A, cGMP-inhibited
51 1672 4.5 4.4 0.3 0.3 -0.492 0.6484 DEFB1 defensin, beta 1
52 258 2.6 2.7 0.2 0.2 0.313 0.7706 AMBN ameloblastin (enamel matrix protein)
53 80162 7.4 7.2 0.1 0.1 -2.712 0.0799 ATHL1 ATH1, acid trehalase-like 1 (yeast)
54 3635 5.6 3.3 1.1 0.9 -2.829 0.0496 INPP5D inositol polyphosphate-5-phosphatase, 145kDa
55 810 8.4 8.9 0.2 0.0 4.559 0.0446 CALML3 calmodulin-like 3
56 54847 8.8 10.1 0.3 0.4 4.691 0.0094 SIDT1 SID1 transmembrane family, member 1
57 6332 2.6 2.6 0.2 0.3 0.180 0.8674 SCN7A sodium channel, voltage gated, type VII alpha subunit
58 10451 8.9 12.3 0.1 0.1 37.542 0.0001 VAV3 vav 3 guanine nucleotide exchange factor
59 83463 9.1 9.1 0.4 0.1 -0.231 0.8367 MXD3 MAX dimerization protein 3
60 79957 13.0 12.0 0.4 0.6 -2.552 0.0746 PAQR6 progestin and adipoQ receptor family member VI
61 5896 2.3 2.2 0.1 0.0 -0.926 0.4481 RAG1 recombination activating gene 1
62 4842 2.4 2.5 0.0 0.2 1.026 0.4043 NOS1 nitric oxide synthase 1 (neuronal)
63 57007 14.2 11.0 0.1 0.4 -13.543 0.0042 ACKR3 atypical chemokine receptor 3
64 8687 2.3 2.3 0.0 0.0 0.222 0.8413 KRT38 keratin 38, type I
65 10716 2.3 2.8 0.0 0.3 3.021 0.0921 TBR1 T-box, brain, 1
66 9472 4.0 2.4 1.5 0.0 -1.947 0.1908 AKAP6 A kinase (PRKA) anchor protein 6
67 113878 8.1 8.6 0.4 0.3 1.585 0.1992 DTX2 deltex 2, E3 ubiquitin ligase
68 10039 5.0 4.6 0.3 0.4 -1.530 0.2067 PARP3 poly (ADP-ribose) polymerase family, member 3
69 27165 7.2 7.7 0.3 0.1 2.340 0.1255 GLS2 glutaminase 2 (liver, mitochondrial)
70 9635 2.9 2.3 1.1 0.0 -0.999 0.4229 CLCA2 chloride channel accessory 2
71 417 2.3 2.4 0.0 0.0 0.921 0.4130 ART1 ADP-ribosyltransferase 1
72 948 9.3 5.1 0.2 0.6 -11.074 0.0040 CD36 CD36 molecule (thrombospondin receptor)
73 1280 3.5 3.4 0.5 0.4 -0.297 0.7818 COL2A1 collagen, type II, alpha 1
74 1805 5.4 5.6 0.1 0.1 2.209 0.1105 DPT dermatopontin
75 27063 5.4 5.0 1.4 0.6 -0.364 0.7430 ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
76 29930 2.4 2.3 0.1 0.0 -1.474 0.2423 PCDHB1 protocadherin beta 1
77 50832 2.8 2.7 0.8 0.7 -0.109 0.9185 TAS2R4 taste receptor, type 2, member 4
78 80144 4.4 5.4 0.3 0.3 4.402 0.0117 FRAS1 Fraser extracellular matrix complex subunit 1
79 10964 2.4 11.5 0.5 0.9 15.974 0.0004 IFI44L interferon-induced protein 44-like
80 25806 9.2 9.7 0.1 0.2 3.251 0.0421 VAX2 ventral anterior homeobox 2
81 1290 6.6 5.9 0.2 0.0 -5.408 0.0315 COL5A2 collagen, type V, alpha 2
82 5087 6.4 6.7 0.2 0.5 1.260 0.3098 PBX1 pre-B-cell leukemia homeobox 1
83 610 9.6 9.7 0.2 0.5 0.280 0.8005 HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
84 80070 2.6 2.4 0.5 0.0 -1.011 0.4172 ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
85 5624 4.3 2.7 0.1 0.5 -5.838 0.0246 PROC protein C (inactivator of coagulation factors Va and VIIIa)
86 3568 2.4 2.4 0.1 0.1 0.247 0.8179 IL5RA interleukin 5 receptor, alpha
87 119 2.6 2.8 0.0 0.1 3.532 0.0505 ADD2 adducin 2 (beta)
88 5816 5.6 5.4 0.1 0.5 -0.628 0.5915 PVALB parvalbumin
89 8350 13.6 13.5 0.2 0.2 -0.746 0.4976 HIST1H3A histone cluster 1, H3a
90 3963 5.7 6.1 0.6 0.2 1.219 0.3325 LGALS7 lectin, galactoside-binding, soluble, 7
91 64108 3.9 4.6 0.7 0.7 1.333 0.2537 RTP4 receptor (chemosensory) transporter protein 4
92 3779 7.9 8.2 0.4 0.3 0.962 0.3921 KCNMB1 potassium channel subfamily M regulatory beta subunit 1
93 4908 3.2 3.2 0.2 0.4 0.250 0.8208 NTF3 neurotrophin 3
94 27202 5.3 6.3 0.4 0.1 4.284 0.0325 C5AR2 complement component 5a receptor 2
95 51214 5.4 5.4 0.3 0.4 0.001 0.9996 IGF2-AS IGF2 antisense RNA
96 55084 4.3 5.7 0.2 0.1 9.877 0.0034 SOBP sine oculis binding protein homolog (Drosophila)
97 9073 2.2 2.2 0.0 0.0 0.517 0.6345 CLDN8 claudin 8
98 84991 10.6 11.0 0.1 0.0 5.741 0.0205 RBM17 RNA binding motif protein 17
99 114088 2.8 2.9 0.2 0.4 0.371 0.7318 TRIM9 tripartite motif containing 9
100 1589 3.6 3.7 0.3 0.5 0.231 0.8302 CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
101 2593 9.7 8.6 0.2 0.1 -7.756 0.0030 GAMT guanidinoacetate N-methyltransferase
102 3834 2.5 3.1 0.3 0.7 1.310 0.2929 KIF25 kinesin family member 25
103 2321 2.4 2.5 0.1 0.1 0.409 0.7102 FLT1 fms-related tyrosine kinase 1
104 388714 2.5 2.4 0.2 0.0 -0.773 0.5162 FMO6P flavin containing monooxygenase 6 pseudogene
105 3449 2.2 2.3 0.0 0.0 0.173 0.8744 IFNA16 interferon, alpha 16
106 4524 5.0 4.8 0.3 0.2 -0.900 0.4358 MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
107 2015 5.8 5.9 0.1 0.1 0.599 0.5820 EMR1 egf-like module containing, mucin-like, hormone receptor-like 1
108 64097 9.7 7.9 0.2 0.7 -4.086 0.0470 EPB41L4A erythrocyte membrane protein band 4.1 like 4A
109 3965 3.7 3.7 0.2 0.1 0.213 0.8422 LGALS9 lectin, galactoside-binding, soluble, 9
110 3485 13.7 13.0 0.2 0.0 -6.918 0.0164 IGFBP2 insulin-like growth factor binding protein 2, 36kDa
111 55258 7.7 7.0 0.3 0.2 -3.402 0.0331 THNSL2 threonine synthase-like 2 (S. cerevisiae)
112 79887 10.2 10.2 0.1 0.1 -0.367 0.7391 PLBD1 phospholipase B domain containing 1
113 221078 7.3 7.7 0.3 0.2 2.002 0.1187 NSUN6 NOP2/Sun domain family, member 6
114 51156 2.7 2.8 0.4 0.4 0.383 0.7214 SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
115 8743 5.1 2.9 0.3 0.2 -10.389 0.0024 TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
116 154661 7.3 8.4 0.0 0.2 9.711 0.0090 RUNDC3B RUN domain containing 3B
117 923 3.1 2.6 0.6 0.7 -0.906 0.4168 CD6 CD6 molecule
118 283345 8.9 9.5 0.4 0.2 2.271 0.1068 RPL13P5 ribosomal protein L13 pseudogene 5
119 64167 4.0 5.2 0.7 0.3 2.604 0.0851 ERAP2 endoplasmic reticulum aminopeptidase 2
120 23242 5.6 6.6 0.1 0.1 11.625 0.0024 COBL cordon-bleu WH2 repeat protein
121 10086 2.6 2.5 0.0 0.0 -1.427 0.2751 HHLA1 HERV-H LTR-associating 1
122 6261 5.8 5.9 0.4 0.1 0.448 0.6944 RYR1 ryanodine receptor 1 (skeletal)
123 2668 4.5 2.5 0.5 0.2 -6.028 0.0104 GDNF glial cell derived neurotrophic factor
124 7915 8.5 9.5 0.3 0.1 5.936 0.0170 ALDH5A1 aldehyde dehydrogenase 5 family, member A1
125 3354 2.4 2.4 0.1 0.2 -0.036 0.9731 HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
126 57523 5.5 5.2 0.2 0.2 -1.553 0.1964 NYNRIN NYN domain and retroviral integrase containing
127 1382 8.8 8.4 0.2 0.8 -0.943 0.4362 CRABP2 cellular retinoic acid binding protein 2
128 623 4.7 4.4 0.3 0.6 -0.883 0.4440 BDKRB1 bradykinin receptor B1
129 10076 9.3 9.2 0.1 0.1 -0.635 0.5609 PTPRU protein tyrosine phosphatase, receptor type, U
130 6536 8.0 7.8 1.4 0.3 -0.190 0.8656 SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
131 10665 2.6 3.1 0.1 0.3 3.106 0.0615 C6orf10 chromosome 6 open reading frame 10
132 8739 9.6 7.9 0.4 0.1 -7.292 0.0097 HRK harakiri, BCL2 interacting protein
133 8578 5.4 6.5 0.6 2.9 0.614 0.5973 SCARF1 scavenger receptor class F, member 1
134 6559 2.7 2.3 0.5 0.0 -1.604 0.2488 SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
135 8911 3.8 3.7 0.1 0.2 -1.164 0.3174 CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
136 5919 3.1 3.1 0.4 0.7 -0.053 0.9609 RARRES2 retinoic acid receptor responder (tazarotene induced) 2
137 79635 5.2 5.6 0.1 0.4 1.660 0.2117 CCDC121 coiled-coil domain containing 121
138 2557 2.3 2.3 0.0 0.0 -0.284 0.7908 GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
139 1014 2.8 3.2 0.4 0.5 1.031 0.3608 CDH16 cadherin 16, KSP-cadherin