Back to Table of Top Pathways

KRAS.LUNG_UP.V1_DN

GeneID Mean_1 Mean_3 StDev_1 StDev_3 T-Statistic p-value SymbolDescription
1 8581 4.9 7.3 0.8 0.5 4.433 0.0162 LY6D lymphocyte antigen 6 complex, locus D
2 6278 3.5 4.7 0.2 0.8 2.459 0.1163 S100A7 S100 calcium binding protein A7
3 3713 3.2 3.4 0.3 0.4 0.851 0.4466 IVL involucrin
4 3851 3.8 4.5 0.6 0.1 1.982 0.1810 KRT4 keratin 4, type II
5 43849 2.5 4.7 0.3 0.5 6.927 0.0048 KLK12 kallikrein-related peptidase 12
6 3868 3.3 6.0 0.7 0.6 5.243 0.0072 KRT16 keratin 16, type I
7 1014 2.8 3.2 0.4 0.5 1.031 0.3608 CDH16 cadherin 16, KSP-cadherin
8 51806 7.9 10.0 0.1 1.0 3.685 0.0656 CALML5 calmodulin-like 5
9 6707 2.9 3.4 0.5 0.9 0.711 0.5293 SPRR3 small proline-rich protein 3
10 3963 5.7 6.1 0.6 0.2 1.219 0.3325 LGALS7 lectin, galactoside-binding, soluble, 7
11 3860 4.9 3.7 0.3 0.2 -5.729 0.0082 KRT13 keratin 13, type I
12 9547 2.8 3.3 0.6 1.0 0.741 0.5092 CXCL14 chemokine (C-X-C motif) ligand 14
13 23242 5.6 6.6 0.1 0.1 11.625 0.0024 COBL cordon-bleu WH2 repeat protein
14 5275 2.3 2.3 0.0 0.0 0.065 0.9510 SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
15 6317 2.4 2.4 0.1 0.0 -0.736 0.5138 SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
16 57016 2.3 6.5 0.0 0.1 103.213 0.0000 AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
17 5608 8.6 4.3 0.1 0.4 -17.882 0.0010 MAP2K6 mitogen-activated protein kinase kinase 6
18 6283 2.5 2.3 0.3 0.0 -0.982 0.4289 S100A12 S100 calcium binding protein A12
19 7051 7.4 7.5 0.2 0.2 0.464 0.6670 TGM1 transglutaminase 1
20 5650 2.3 2.3 0.0 0.0 -0.113 0.9170 KLK7 kallikrein-related peptidase 7
21 55 4.0 4.8 0.4 0.2 3.307 0.0360 ACPP acid phosphatase, prostate
22 10631 2.8 2.6 0.3 0.1 -1.086 0.3593 POSTN periostin, osteoblast specific factor
23 8424 3.0 3.8 0.7 1.8 0.781 0.4983 BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
24 1410 5.0 4.2 0.1 0.2 -5.932 0.0058 CRYAB crystallin, alpha B
25 11254 2.6 10.8 0.8 0.3 15.953 0.0013 SLC6A14 solute carrier family 6 (amino acid transporter), member 14
26 9935 8.0 10.3 0.5 0.1 8.079 0.0114 MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
27 57124 2.7 3.0 0.7 0.7 0.400 0.7096 CD248 CD248 molecule, endosialin
28 3635 5.6 3.3 1.1 0.9 -2.829 0.0496 INPP5D inositol polyphosphate-5-phosphatase, 145kDa
29 64108 3.9 4.6 0.7 0.7 1.333 0.2537 RTP4 receptor (chemosensory) transporter protein 4
30 1954 10.8 10.4 0.8 0.4 -0.671 0.5503 MEGF8 multiple EGF-like-domains 8
31 5287 8.4 8.7 0.2 0.2 2.242 0.0884 PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
32 23616 4.9 5.3 0.2 0.3 1.992 0.1333 SH3BP1 SH3-domain binding protein 1
33 3351 3.9 4.0 0.6 0.4 0.131 0.9025 HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
34 3848 2.2 5.7 0.0 1.6 3.798 0.0628 KRT1 keratin 1, type II
35 27113 12.3 11.5 0.8 0.2 -1.769 0.2068 BBC3 BCL2 binding component 3
36 79755 6.8 7.2 0.5 0.7 0.778 0.4841 ZNF750 zinc finger protein 750
37 170679 7.0 7.0 0.3 0.7 0.038 0.9724 PSORS1C1 psoriasis susceptibility 1 candidate 1
38 1672 4.5 4.4 0.3 0.3 -0.492 0.6484 DEFB1 defensin, beta 1
39 5625 6.7 6.9 0.1 0.2 1.339 0.2517 PRODH proline dehydrogenase (oxidase) 1
40 23498 3.4 4.3 0.4 0.5 2.328 0.0823 HAAO 3-hydroxyanthranilate 3,4-dioxygenase
41 6261 5.8 5.9 0.4 0.1 0.448 0.6944 RYR1 ryanodine receptor 1 (skeletal)
42 1280 3.5 3.4 0.5 0.4 -0.297 0.7818 COL2A1 collagen, type II, alpha 1
43 129080 8.6 7.7 0.2 0.1 -7.165 0.0042 EMID1 EMI domain containing 1
44 169611 4.6 5.2 0.2 0.1 4.875 0.0194 OLFML2A olfactomedin-like 2A
45 51384 2.2 2.2 0.0 0.0 0.210 0.8494 WNT16 wingless-type MMTV integration site family, member 16
46 57399 2.4 2.5 0.3 0.5 0.258 0.8106 LOC57399 uncharacterized gastric protein ZA52P
47 57523 5.5 5.2 0.2 0.2 -1.553 0.1964 NYNRIN NYN domain and retroviral integrase containing
48 22802 2.6 2.8 0.1 0.4 0.938 0.4326 CLCA4 chloride channel accessory 4
49 282808 7.2 6.8 0.2 0.1 -4.053 0.0322 RAB40AL RAB40A, member RAS oncogene family-like
50 51458 4.7 5.8 0.3 0.2 5.573 0.0052 RHCG Rh family, C glycoprotein
51 10076 9.3 9.2 0.1 0.1 -0.635 0.5609 PTPRU protein tyrosine phosphatase, receptor type, U
52 79097 3.1 2.9 0.8 0.4 -0.405 0.7140 TRIM48 tripartite motif containing 48
53 79696 6.0 6.1 0.4 0.3 0.526 0.6292 ZC2HC1C zinc finger, C2HC-type containing 1C
54 8852 3.5 3.4 0.0 0.1 -2.519 0.0920 AKAP4 A kinase (PRKA) anchor protein 4
55 11202 3.6 7.0 1.0 0.1 5.839 0.0265 KLK8 kallikrein-related peptidase 8
56 10249 2.5 2.6 0.2 0.2 0.787 0.4771 GLYAT glycine-N-acyltransferase
57 4804 3.7 3.7 0.3 0.6 -0.060 0.9558 NGFR nerve growth factor receptor
58 200315 2.8 2.2 1.0 0.0 -1.021 0.4146 APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
59 79644 7.1 7.5 0.0 0.3 2.502 0.1248 SRD5A3 steroid 5 alpha-reductase 3
60 2327 3.0 2.3 1.1 0.0 -1.011 0.4180 FMO2 flavin containing monooxygenase 2 (non-functional)
61 1028 6.7 6.4 0.3 0.2 -1.560 0.1976 CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
62 27076 6.9 8.1 0.3 0.2 5.629 0.0121 LYPD3 LY6/PLAUR domain containing 3
63 8608 5.7 5.3 0.9 0.2 -0.725 0.5369 RDH16 retinol dehydrogenase 16 (all-trans)
64 8578 5.4 6.5 0.6 2.9 0.614 0.5973 SCARF1 scavenger receptor class F, member 1
65 26290 2.8 2.8 0.2 0.3 0.167 0.8766 GALNT8 polypeptide N-acetylgalactosaminyltransferase 8
66 11012 2.3 11.1 0.0 0.5 31.539 0.0010 KLK11 kallikrein-related peptidase 11
67 222 9.7 9.3 0.3 0.2 -2.186 0.1166 ALDH3B2 aldehyde dehydrogenase 3 family, member B2
68 8399 5.8 5.7 0.6 0.3 -0.434 0.6951 PLA2G10 phospholipase A2, group X
69 5158 7.0 5.7 0.1 0.8 -2.922 0.0966 PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
70 1382 8.8 8.4 0.2 0.8 -0.943 0.4362 CRABP2 cellular retinoic acid binding protein 2
71 56603 2.9 2.7 0.8 0.4 -0.442 0.6889 CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
72 6318 2.4 2.4 0.0 0.0 0.005 0.9962 SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
73 3485 13.7 13.0 0.2 0.0 -6.918 0.0164 IGFBP2 insulin-like growth factor binding protein 2, 36kDa
74 7441 2.3 2.3 0.0 0.0 -0.556 0.6081 VPREB1 pre-B lymphocyte 1
75 729230 3.7 3.4 1.1 1.6 -0.325 0.7630 CCR2 chemokine (C-C motif) receptor 2
76 3866 10.4 9.0 0.3 0.4 -4.676 0.0140 KRT15 keratin 15, type I
77 10451 8.9 12.3 0.1 0.1 37.542 0.0001 VAV3 vav 3 guanine nucleotide exchange factor
78 55776 9.6 9.5 0.2 0.1 -0.885 0.4492 SAYSD1 SAYSVFN motif domain containing 1
79 8495 7.5 7.4 0.6 0.7 -0.194 0.8564 PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
80 9472 4.0 2.4 1.5 0.0 -1.947 0.1908 AKAP6 A kinase (PRKA) anchor protein 6
81 810 8.4 8.9 0.2 0.0 4.559 0.0446 CALML3 calmodulin-like 3
82 6519 2.7 2.5 0.1 0.2 -1.141 0.3344 SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
83 3549 2.5 3.3 0.6 0.8 1.398 0.2447 IHH indian hedgehog
84 1310 2.6 2.7 0.1 0.4 0.321 0.7770 COL19A1 collagen, type XIX, alpha 1
85 54587 2.4 2.3 0.3 0.0 -1.010 0.4162 MXRA8 matrix-remodelling associated 8
86 1562 2.2 2.2 0.0 0.0 0.451 0.6926 CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18
87 2619 3.2 3.9 1.0 1.2 0.801 0.4701 GAS1 growth arrest-specific 1
88 2560 3.1 3.0 0.2 0.1 -0.916 0.4140 GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
89 6457 7.4 7.1 0.3 0.3 -0.953 0.3947 SH3GL3 SH3-domain GRB2-like 3
90 79703 7.1 7.5 0.4 0.1 1.550 0.2561 C11orf80 chromosome 11 open reading frame 80
91 8743 5.1 2.9 0.3 0.2 -10.389 0.0024 TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
92 23493 6.9 7.3 0.7 0.5 0.745 0.5004 HEY2 hes-related family bHLH transcription factor with YRPW motif 2
93 29953 2.9 2.8 0.2 0.3 -0.271 0.8022 TRHDE thyrotropin-releasing hormone degrading enzyme
94 3352 2.8 3.1 0.5 0.4 0.813 0.4657 HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
95 1580 6.7 6.6 0.3 0.5 -0.268 0.8046 CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
96 6444 3.1 2.9 0.5 0.2 -0.746 0.5181 SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
97 6536 8.0 7.8 1.4 0.3 -0.190 0.8656 SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
98 11063 3.8 4.2 0.5 0.5 0.830 0.4537 SOX30 SRY (sex determining region Y)-box 30
99 25840 12.7 12.0 0.1 0.4 -2.710 0.0993 METTL7A methyltransferase like 7A
100 933 3.0 3.5 0.4 1.8 0.460 0.6871 CD22 CD22 molecule
101 80761 8.0 5.5 0.1 0.1 -34.302 0.0000 UPK3B uroplakin 3B
102 867 8.4 8.5 0.4 0.5 0.376 0.7268 CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
103 643641 9.8 10.2 0.1 0.1 8.661 0.0011 ZNF862 zinc finger protein 862
104 55610 6.3 6.8 0.2 0.1 4.951 0.0222 CCDC132 coiled-coil domain containing 132
105 81628 9.6 10.0 0.4 0.2 1.263 0.3045 TSC22D4 TSC22 domain family, member 4
106 79132 5.9 11.0 0.3 0.3 19.290 0.0001 DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
107 6336 2.2 2.2 0.0 0.0 -0.646 0.5543 SCN10A sodium channel, voltage gated, type X alpha subunit
108 119 2.6 2.8 0.0 0.1 3.532 0.0505 ADD2 adducin 2 (beta)
109 100507605 3.4 2.3 1.8 0.0 -1.021 0.4145 LINC00837 long intergenic non-protein coding RNA 837
110 27136 3.5 2.5 2.0 0.2 -0.852 0.4827 MORC1 MORC family CW-type zinc finger 1
111 3587 5.3 2.6 1.0 0.2 -4.687 0.0340 IL10RA interleukin 10 receptor, alpha
112 1133 2.8 3.1 0.4 0.3 0.975 0.3954 CHRM5 cholinergic receptor, muscarinic 5
113 5624 4.3 2.7 0.1 0.5 -5.838 0.0246 PROC protein C (inactivator of coagulation factors Va and VIIIa)
114 43 6.1 6.4 0.4 0.3 1.045 0.3591 ACHE acetylcholinesterase (Yt blood group)
115 9651 5.1 5.1 0.1 0.2 -0.103 0.9236 PLCH2 phospholipase C, eta 2
116 778 3.1 2.3 1.4 0.0 -1.005 0.4205 CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit
117 2049 7.6 9.2 0.4 0.3 5.606 0.0083 EPHB3 EPH receptor B3
118 2078 2.3 2.7 0.1 0.3 2.051 0.1704 ERG v-ets avian erythroblastosis virus E26 oncogene homolog
119 4004 9.5 8.5 0.6 0.2 -2.775 0.0886 LMO1 LIM domain only 1 (rhombotin 1)
120 8392 3.4 4.4 1.0 0.2 1.534 0.2579 OR3A3 olfactory receptor, family 3, subfamily A, member 3
121 4214 11.6 11.1 0.1 0.1 -4.921 0.0154 MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
122 8842 3.8 2.6 0.7 0.2 -2.953 0.0863 PROM1 prominin 1
123 79725 7.4 7.2 0.9 0.2 -0.431 0.7041 THAP9 THAP domain containing 9
124 10457 4.0 3.9 0.3 0.5 -0.142 0.8949 GPNMB glycoprotein (transmembrane) nmb
125 7018 4.1 3.5 1.4 0.3 -0.712 0.5459 TF transferrin
126 11250 3.2 3.2 0.9 0.7 0.018 0.9865 GPR45 G protein-coupled receptor 45
127 6981 5.4 3.4 0.4 0.9 -3.549 0.0443 TRGV7 T cell receptor gamma variable 7 (pseudogene)
128 140 2.5 2.2 0.5 0.0 -1.027 0.4122 ADORA3 adenosine A3 receptor
129 4161 2.6 2.6 0.4 0.4 -0.201 0.8503 MC5R melanocortin 5 receptor
130 5896 2.3 2.2 0.1 0.0 -0.926 0.4481 RAG1 recombination activating gene 1
131 11341 2.4 2.4 0.0 0.1 0.504 0.6491 SCRG1 stimulator of chondrogenesis 1
132 5064 12.4 12.1 0.2 0.4 -1.310 0.2769 PALM paralemmin
133 29986 2.4 2.5 0.0 0.1 1.683 0.2286 SLC39A2 solute carrier family 39 (zinc transporter), member 2
134 1010 2.7 4.8 0.6 0.3 5.484 0.0128 CDH12 cadherin 12, type 2 (N-cadherin 2)
135 2668 4.5 2.5 0.5 0.2 -6.028 0.0104 GDNF glial cell derived neurotrophic factor
136 7356 6.7 6.7 0.2 0.1 -0.120 0.9119 SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
137 5540 4.6 4.8 0.1 0.2 1.300 0.2658 NPY4R neuropeptide Y receptor Y4
138 6712 8.9 8.7 0.2 0.0 -1.988 0.1666 SPTBN2 spectrin, beta, non-erythrocytic 2
139 79969 8.6 8.4 0.1 0.3 -1.394 0.2692 ATAT1 alpha tubulin acetyltransferase 1