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KRAS.300_UP.V1_DN

GeneID Mean_1 Mean_3 StDev_1 StDev_3 T-Statistic p-value SymbolDescription
1 3860 4.9 3.7 0.3 0.2 -5.729 0.0082 KRT13 keratin 13, type I
2 6278 3.5 4.7 0.2 0.8 2.459 0.1163 S100A7 S100 calcium binding protein A7
3 3851 3.8 4.5 0.6 0.1 1.982 0.1810 KRT4 keratin 4, type II
4 3868 3.3 6.0 0.7 0.6 5.243 0.0072 KRT16 keratin 16, type I
5 7051 7.4 7.5 0.2 0.2 0.464 0.6670 TGM1 transglutaminase 1
6 1014 2.8 3.2 0.4 0.5 1.031 0.3608 CDH16 cadherin 16, KSP-cadherin
7 57007 14.2 11.0 0.1 0.4 -13.543 0.0042 ACKR3 atypical chemokine receptor 3
8 4842 2.4 2.5 0.0 0.2 1.026 0.4043 NOS1 nitric oxide synthase 1 (neuronal)
9 2053 10.8 9.4 0.1 0.6 -4.199 0.0484 EPHX2 epoxide hydrolase 2, cytoplasmic
10 10964 2.4 11.5 0.5 0.9 15.974 0.0004 IFI44L interferon-induced protein 44-like
11 8687 2.3 2.3 0.0 0.0 0.222 0.8413 KRT38 keratin 38, type I
12 51214 5.4 5.4 0.3 0.4 0.001 0.9996 IGF2-AS IGF2 antisense RNA
13 8581 4.9 7.3 0.8 0.5 4.433 0.0162 LY6D lymphocyte antigen 6 complex, locus D
14 6699 3.7 4.2 0.4 0.4 1.535 0.2006 SPRR1B small proline-rich protein 1B
15 11254 2.6 10.8 0.8 0.3 15.953 0.0013 SLC6A14 solute carrier family 6 (amino acid transporter), member 14
16 3834 2.5 3.1 0.3 0.7 1.310 0.2929 KIF25 kinesin family member 25
17 5275 2.3 2.3 0.0 0.0 0.065 0.9510 SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
18 6707 2.9 3.4 0.5 0.9 0.711 0.5293 SPRR3 small proline-rich protein 3
19 4600 5.2 5.4 0.2 0.2 1.718 0.1625 MX2 MX dynamin-like GTPase 2
20 27202 5.3 6.3 0.4 0.1 4.284 0.0325 C5AR2 complement component 5a receptor 2
21 7068 4.4 4.3 0.2 0.2 -0.655 0.5529 THRB thyroid hormone receptor, beta
22 6236 2.3 2.6 0.1 0.6 0.854 0.4807 RRAD Ras-related associated with diabetes
23 6664 2.3 2.8 0.1 1.0 0.900 0.4625 SOX11 SRY (sex determining region Y)-box 11
24 5790 7.3 6.9 0.1 0.3 -1.977 0.1644 PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
25 149628 3.7 3.6 0.2 0.2 -0.982 0.3817 PYHIN1 pyrin and HIN domain family, member 1
26 8541 8.5 8.3 0.3 0.2 -0.511 0.6393 PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
27 4908 3.2 3.2 0.2 0.4 0.250 0.8208 NTF3 neurotrophin 3
28 3351 3.9 4.0 0.6 0.4 0.131 0.9025 HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
29 7226 2.5 3.0 0.3 0.6 1.296 0.2898 TRPM2 transient receptor potential cation channel, subfamily M, member 2
30 6531 3.7 3.8 0.1 0.0 4.581 0.0143 SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
31 525 5.0 5.8 0.4 0.1 3.418 0.0652 ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
32 79861 3.4 5.6 0.3 1.1 3.416 0.0647 TUBAL3 tubulin, alpha-like 3
33 10993 3.2 3.0 0.1 0.4 -0.563 0.6232 SDS serine dehydratase
34 5243 2.7 2.9 0.4 0.3 0.810 0.4673 ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
35 29930 2.4 2.3 0.1 0.0 -1.474 0.2423 PCDHB1 protocadherin beta 1
36 79887 10.2 10.2 0.1 0.1 -0.367 0.7391 PLBD1 phospholipase B domain containing 1
37 2051 2.4 3.6 0.0 0.5 4.436 0.0455 EPHB6 EPH receptor B6
38 1421 3.1 3.1 0.3 0.4 0.114 0.9156 CRYGD crystallin, gamma D
39 50832 2.8 2.7 0.8 0.7 -0.109 0.9185 TAS2R4 taste receptor, type 2, member 4
40 169611 4.6 5.2 0.2 0.1 4.875 0.0194 OLFML2A olfactomedin-like 2A
41 23553 6.8 6.7 0.0 0.1 -1.199 0.3025 HYAL4 hyaluronoglucosaminidase 4
42 1237 2.4 2.4 0.3 0.2 -0.066 0.9510 CCR8 chemokine (C-C motif) receptor 8
43 10669 10.2 10.5 0.1 0.2 2.143 0.1030 CGREF1 cell growth regulator with EF-hand domain 1
44 7356 6.7 6.7 0.2 0.1 -0.120 0.9119 SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
45 170679 7.0 7.0 0.3 0.7 0.038 0.9724 PSORS1C1 psoriasis susceptibility 1 candidate 1
46 10912 9.7 9.5 0.2 0.3 -0.771 0.4978 GADD45G growth arrest and DNA-damage-inducible, gamma
47 259197 3.2 3.3 0.2 0.2 0.241 0.8220 NCR3 natural cytotoxicity triggering receptor 3
48 2912 2.5 2.9 0.1 0.5 1.408 0.2895 GRM2 glutamate receptor, metabotropic 2
49 23498 3.4 4.3 0.4 0.5 2.328 0.0823 HAAO 3-hydroxyanthranilate 3,4-dioxygenase
50 25861 6.2 6.5 0.2 0.2 1.839 0.1423 DFNB31 deafness, autosomal recessive 31
51 8431 3.5 3.3 0.5 0.1 -0.778 0.5126 NR0B2 nuclear receptor subfamily 0, group B, member 2
52 57016 2.3 6.5 0.0 0.1 103.213 0.0000 AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
53 8743 5.1 2.9 0.3 0.2 -10.389 0.0024 TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
54 10686 2.3 2.4 0.3 0.4 0.161 0.8799 CLDN16 claudin 16
55 1838 5.5 5.8 0.3 0.3 1.327 0.2590 DTNB dystrobrevin, beta
56 10398 3.6 3.5 0.5 0.3 -0.303 0.7821 MYL9 myosin, light chain 9, regulatory
57 676 2.7 2.7 0.2 0.3 0.281 0.7947 BRDT bromodomain, testis-specific
58 57118 8.8 9.0 0.0 0.3 1.201 0.3520 CAMK1D calcium/calmodulin-dependent protein kinase ID
59 25809 8.3 8.1 0.5 0.5 -0.608 0.5759 TTLL1 tubulin tyrosine ligase-like family member 1
60 54209 3.2 2.3 1.6 0.0 -1.008 0.4195 TREM2 triggering receptor expressed on myeloid cells 2
61 3955 8.7 9.4 0.1 0.2 4.964 0.0110 LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
62 79990 12.7 12.3 0.4 0.2 -1.904 0.1384 PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
63 79917 5.6 5.9 0.2 0.4 1.098 0.3659 MAGIX MAGI family member, X-linked
64 8911 3.8 3.7 0.1 0.2 -1.164 0.3174 CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
65 3352 2.8 3.1 0.5 0.4 0.813 0.4657 HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
66 29881 5.3 4.9 0.3 0.5 -1.155 0.3201 NPC1L1 NPC1-like 1
67 867 8.4 8.5 0.4 0.5 0.376 0.7268 CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
68 27254 2.2 2.3 0.0 0.2 1.046 0.4032 CSDC2 cold shock domain containing C2, RNA binding
69 26083 2.4 5.0 0.1 3.8 1.178 0.3599 TBC1D29 TBC1 domain family, member 29
70 23242 5.6 6.6 0.1 0.1 11.625 0.0024 COBL cordon-bleu WH2 repeat protein
71 5158 7.0 5.7 0.1 0.8 -2.922 0.0966 PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
72 2633 2.6 2.4 0.5 0.0 -0.927 0.4501 GBP1 guanylate binding protein 1, interferon-inducible
73 154661 7.3 8.4 0.0 0.2 9.711 0.0090 RUNDC3B RUN domain containing 3B
74 3848 2.2 5.7 0.0 1.6 3.798 0.0628 KRT1 keratin 1, type II
75 1521 2.3 2.4 0.0 0.2 1.343 0.3100 CTSW cathepsin W
76 51754 8.1 7.6 0.2 0.5 -1.874 0.1571 TMEM8B transmembrane protein 8B
77 4261 2.7 3.2 0.3 0.6 1.466 0.2481 CIITA class II, major histocompatibility complex, transactivator
78 10913 2.4 2.3 0.0 0.0 -1.124 0.3291 EDAR ectodysplasin A receptor
79 3963 5.7 6.1 0.6 0.2 1.219 0.3325 LGALS7 lectin, galactoside-binding, soluble, 7
80 684 12.9 14.3 0.2 0.1 8.827 0.0058 BST2 bone marrow stromal cell antigen 2
81 8437 6.7 7.5 0.2 0.3 4.344 0.0167 RASAL1 RAS protein activator like 1 (GAP1 like)
82 2261 9.7 6.8 0.1 0.5 -9.721 0.0096 FGFR3 fibroblast growth factor receptor 3
83 1807 2.9 2.3 1.0 0.0 -0.990 0.4264 DPYS dihydropyrimidinase
84 54847 8.8 10.1 0.3 0.4 4.691 0.0094 SIDT1 SID1 transmembrane family, member 1
85 56287 2.2 3.8 0.0 2.5 1.114 0.3812 GKN1 gastrokine 1
86 1382 8.8 8.4 0.2 0.8 -0.943 0.4362 CRABP2 cellular retinoic acid binding protein 2
87 5608 8.6 4.3 0.1 0.4 -17.882 0.0010 MAP2K6 mitogen-activated protein kinase kinase 6
88 1805 5.4 5.6 0.1 0.1 2.209 0.1105 DPT dermatopontin
89 7782 4.5 4.9 0.2 0.4 1.574 0.2248 SLC30A4 solute carrier family 30 (zinc transporter), member 4
90 1830 2.4 2.5 0.1 0.1 0.222 0.8366 DSG3 desmoglein 3
91 10242 2.3 2.3 0.0 0.1 -0.339 0.7557 KCNMB2 potassium channel subfamily M regulatory beta subunit 2
92 83463 9.1 9.1 0.4 0.1 -0.231 0.8367 MXD3 MAX dimerization protein 3
93 1129 3.5 3.0 0.7 0.3 -1.095 0.3572 CHRM2 cholinergic receptor, muscarinic 2
94 11238 6.1 5.9 0.2 0.1 -1.554 0.2204 CA5B carbonic anhydrase VB, mitochondrial
95 11346 4.2 8.0 0.0 0.2 42.549 0.0004 SYNPO synaptopodin
96 113878 8.1 8.6 0.4 0.3 1.585 0.1992 DTX2 deltex 2, E3 ubiquitin ligase
97 5624 4.3 2.7 0.1 0.5 -5.838 0.0246 PROC protein C (inactivator of coagulation factors Va and VIIIa)
98 7137 5.2 6.0 0.2 0.3 3.948 0.0193 TNNI3 troponin I type 3 (cardiac)
99 4825 2.7 2.4 0.5 0.0 -0.998 0.4224 NKX6-1 NK6 homeobox 1
100 3753 3.4 3.0 0.4 0.5 -1.055 0.3545 KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
101 6519 2.7 2.5 0.1 0.2 -1.141 0.3344 SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
102 338 2.6 2.4 0.2 0.0 -1.943 0.1863 APOB apolipoprotein B
103 10085 2.6 2.1 0.9 0.0 -0.999 0.4231 EDIL3 EGF-like repeats and discoidin I-like domains 3
104 92154 9.4 10.0 0.2 0.2 4.861 0.0085 MTSS1L metastasis suppressor 1-like
105 50853 4.5 5.1 0.2 1.0 1.003 0.4117 VILL villin-like
106 55534 6.6 6.1 0.1 0.3 -2.541 0.1034 MAML3 mastermind-like 3 (Drosophila)
107 54587 2.4 2.3 0.3 0.0 -1.010 0.4162 MXRA8 matrix-remodelling associated 8
108 258 2.6 2.7 0.2 0.2 0.313 0.7706 AMBN ameloblastin (enamel matrix protein)
109 6876 7.2 6.8 0.4 0.7 -0.715 0.5228 TAGLN transgelin
110 7104 2.7 2.7 0.4 0.5 0.094 0.9299 TM4SF4 transmembrane 4 L six family member 4
111 79883 3.4 5.2 0.7 0.1 4.241 0.0491 PODNL1 podocan-like 1
112 51087 11.9 11.9 0.3 0.1 0.047 0.9662 YBX2 Y box binding protein 2
113 10584 2.2 2.2 0.0 0.0 0.675 0.5406 COLEC10 collectin sub-family member 10 (C-type lectin)
114 72 4.0 5.1 0.2 0.3 4.572 0.0130 ACTG2 actin, gamma 2, smooth muscle, enteric
115 5626 3.0 2.3 0.7 0.0 -1.732 0.2247 PROP1 PROP paired-like homeobox 1
116 79755 6.8 7.2 0.5 0.7 0.778 0.4841 ZNF750 zinc finger protein 750
117 79958 2.7 3.1 0.3 0.2 1.989 0.1258 DENND1C DENN/MADD domain containing 1C
118 10307 7.8 7.7 0.2 0.4 -0.605 0.5877 APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
119 6262 2.4 2.4 0.1 0.1 0.216 0.8401 RYR2 ryanodine receptor 2 (cardiac)
120 56154 3.7 2.9 0.9 0.4 -1.525 0.2337 TEX15 testis expressed 15
121 5023 2.5 2.4 0.2 0.2 -0.539 0.6204 P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
122 1048 2.4 2.5 0.2 0.5 0.491 0.6568 CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
123 84679 8.0 8.4 0.1 0.2 3.113 0.0655 SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
124 6712 8.9 8.7 0.2 0.0 -1.988 0.1666 SPTBN2 spectrin, beta, non-erythrocytic 2
125 2299 2.2 7.4 0.0 1.2 7.423 0.0177 FOXI1 forkhead box I1
126 4938 2.5 8.5 0.3 0.7 14.698 0.0014 OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
127 64108 3.9 4.6 0.7 0.7 1.333 0.2537 RTP4 receptor (chemosensory) transporter protein 4
128 4599 8.0 8.4 0.2 0.3 1.930 0.1384 MX1 MX dynamin-like GTPase 1
129 50940 2.7 2.3 0.4 0.0 -1.955 0.1892 PDE11A phosphodiesterase 11A
130 9468 2.5 2.5 0.1 0.1 0.318 0.7679 PCYT1B phosphate cytidylyltransferase 1, choline, beta
131 23495 3.2 2.7 0.6 0.6 -1.118 0.3270 TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
132 959 2.3 2.7 0.0 0.8 1.030 0.4114 CD40LG CD40 ligand
133 388714 2.5 2.4 0.2 0.0 -0.773 0.5162 FMO6P flavin containing monooxygenase 6 pseudogene
134 3218 2.3 2.3 0.0 0.0 -0.156 0.8843 HOXB8 homeobox B8
135 3786 6.0 5.8 0.1 0.2 -1.402 0.2574 KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
136 26353 10.7 11.6 0.2 0.0 8.806 0.0088 HSPB8 heat shock 22kDa protein 8
137 4586 4.0 4.2 0.5 0.3 0.415 0.7023 MUC5AC mucin 5AC, oligomeric mucus/gel-forming