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Sunitinib

GeneID Mean_1 Mean_3 StDev_1 StDev_3 T-Statistic p-value SymbolDescription
1 19 3.0 2.4 0.6 0.1 -1.605 0.2442 ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
2 9429 2.8 6.4 0.5 0.3 11.391 0.0013 ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
3 213 3.2 2.8 0.4 0.5 -1.148 0.3190 ALB albumin
4 238 2.5 2.5 0.1 0.1 0.197 0.8553 ALK anaplastic lymphoma receptor tyrosine kinase
5 9582 8.2 8.1 0.2 0.3 -0.879 0.4371 APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
6 51761 2.8 4.2 0.2 0.2 8.068 0.0017 ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
7 9212 8.7 10.0 0.2 0.2 7.824 0.0014 AURKB aurora kinase B
8 558 7.0 7.0 0.2 0.2 -0.021 0.9840 AXL AXL receptor tyrosine kinase
9 596 10.3 10.3 0.2 0.1 0.739 0.5268 BCL2 B-cell CLL/lymphoma 2
10 55589 5.2 6.6 0.1 0.1 12.885 0.0002 BMP2K BMP2 inducible kinase
11 78996 9.9 11.0 0.2 0.1 9.881 0.0048 C7orf49 chromosome 7 open reading frame 49
12 836 8.2 8.0 0.3 0.2 -1.211 0.3082 CASP3 caspase 3, apoptosis-related cysteine peptidase
13 947 2.6 2.4 0.1 0.1 -2.834 0.0480 CD34 CD34 molecule
14 920 12.3 12.1 0.1 0.3 -1.157 0.3384 CD4 CD4 molecule
15 81620 13.0 13.5 0.6 0.1 1.278 0.3241 CDT1 chromatin licensing and DNA replication factor 1
16 83548 10.1 10.1 0.0 0.2 0.698 0.5574 COG3 component of oligomeric golgi complex 3
17 1436 3.7 2.9 0.1 0.4 -3.787 0.0406 CSF1R colony stimulating factor 1 receptor
18 1437 2.3 2.3 0.0 0.0 0.420 0.7020 CSF2 colony stimulating factor 2 (granulocyte-macrophage)
19 1455 10.9 11.0 0.1 0.1 1.296 0.2694 CSNK1G2 casein kinase 1, gamma 2
20 6387 7.9 8.5 0.3 0.3 2.040 0.1110 CXCL12 chemokine (C-X-C motif) ligand 12
21 114757 13.4 13.0 0.1 0.2 -2.755 0.0760 CYGB cytoglobin
22 1558 2.2 2.8 0.0 0.6 1.477 0.2775 CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
23 4921 2.6 2.9 0.4 0.4 0.964 0.3899 DDR2 discoidin domain receptor tyrosine kinase 2
24 1950 2.3 2.4 0.0 0.1 1.016 0.4144 EGF epidermal growth factor
25 1956 2.9 3.3 0.2 0.1 3.112 0.0782 EGFR epidermal growth factor receptor
26 1999 10.5 10.5 0.1 0.7 0.018 0.9875 ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
27 2048 5.7 5.8 0.3 0.2 0.700 0.5288 EPHB2 EPH receptor B2
28 2064 9.7 9.0 0.4 0.3 -2.344 0.0865 ERBB2 erb-b2 receptor tyrosine kinase 2
29 2158 2.3 2.3 0.0 0.0 0.072 0.9471 F9 coagulation factor IX
30 144717 7.2 7.6 0.2 0.2 2.499 0.0694 FAM109A family with sequence similarity 109, member A
31 2258 4.8 6.2 0.4 0.4 4.282 0.0135 FGF13 fibroblast growth factor 13
32 2321 2.4 2.5 0.1 0.1 0.409 0.7102 FLT1 fms-related tyrosine kinase 1
33 2322 5.4 8.4 0.2 0.0 22.015 0.0014 FLT3 fms-related tyrosine kinase 3
34 2324 4.1 4.4 0.2 0.1 3.492 0.0353 FLT4 fms-related tyrosine kinase 4
35 2645 4.8 4.7 0.1 0.2 -0.602 0.5904 GCK glucokinase (hexokinase 4)
36 3043 2.4 2.4 0.0 0.0 0.209 0.8450 HBB hemoglobin, beta
37 3091 9.2 9.4 0.1 0.0 3.235 0.0743 HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
38 3265 10.7 10.7 0.2 0.4 -0.278 0.8001 HRAS Harvey rat sarcoma viral oncogene homolog
39 56912 9.6 9.7 0.2 0.2 0.834 0.4511 IFT46 intraflagellar transport 46
40 3558 2.5 2.4 0.1 0.1 -0.771 0.4998 IL2 interleukin 2
41 3562 2.5 2.6 0.1 0.2 0.361 0.7433 IL3 interleukin 3
42 3569 2.3 2.3 0.0 0.0 -0.440 0.6964 IL6 interleukin 6
43 3630 3.6 4.1 0.4 0.4 1.716 0.1617 INS insulin
44 3791 2.4 2.3 0.0 0.1 -0.496 0.6472 KDR kinase insert domain receptor
45 3815 2.3 2.3 0.1 0.0 -0.184 0.8629 KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
46 3939 13.5 13.5 0.2 0.3 0.040 0.9697 LDHA lactate dehydrogenase A
47 4217 7.7 7.7 0.1 0.1 0.239 0.8256 MAP3K5 mitogen-activated protein kinase kinase kinase 5
48 5595 8.9 9.2 0.3 0.1 1.920 0.1525 MAPK3 mitogen-activated protein kinase 3
49 4233 9.9 11.6 0.1 0.1 28.016 0.0001 MET MET proto-oncogene, receptor tyrosine kinase
50 4318 10.6 9.4 0.1 0.3 -6.225 0.0138 MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
51 2475 8.9 9.1 0.0 0.1 3.319 0.0559 MTOR mechanistic target of rapamycin (serine/threonine kinase)
52 4846 7.8 7.0 0.1 0.3 -4.351 0.0334 NOS3 nitric oxide synthase 3 (endothelial cell)
53 10133 7.3 7.4 0.2 0.1 1.199 0.3034 OPTN optineurin
54 54995 11.7 11.5 0.1 0.1 -2.995 0.0418 OXSM 3-oxoacyl-ACP synthase, mitochondrial
55 57144 2.9 2.4 1.0 0.0 -0.943 0.4450 PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
56 5156 2.3 2.3 0.0 0.0 0.365 0.7443 PDGFRA platelet-derived growth factor receptor, alpha polypeptide
57 5159 2.3 2.3 0.0 0.0 0.990 0.3792 PDGFRB platelet-derived growth factor receptor, beta polypeptide
58 5260 4.8 4.7 0.2 0.0 -0.542 0.6382 PHKG1 phosphorylase kinase, gamma 1 (muscle)
59 5261 8.4 8.7 0.3 0.1 1.458 0.2555 PHKG2 phosphorylase kinase, gamma 2 (testis)
60 55558 11.7 11.8 0.2 0.2 0.458 0.6717 PLXNA3 plexin A3
61 5468 2.3 4.0 0.0 0.5 5.713 0.0291 PPARG peroxisome proliferator-activated receptor gamma
62 7001 12.0 12.1 0.1 0.0 3.370 0.0339 PRDX2 peroxiredoxin 2
63 5728 10.1 9.8 0.0 0.1 -3.208 0.0714 PTEN phosphatase and tensin homolog
64 5923 3.0 2.3 1.2 0.1 -0.992 0.4255 RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
65 677775 7.5 7.5 0.1 0.1 -0.090 0.9327 SCARNA5 small Cajal body-specific RNA 5
66 29072 8.7 8.7 0.0 0.0 0.189 0.8593 SETD2 SET domain containing 2
67 788 8.3 7.5 0.1 0.4 -3.731 0.0611 SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
68 9748 9.5 9.6 0.1 0.2 0.590 0.6044 SLK STE20-like kinase
69 23583 9.9 9.9 0.1 0.0 0.634 0.5814 SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
70 6750 2.5 2.5 0.1 0.3 0.480 0.6656 SST somatostatin
71 6774 7.9 7.4 0.2 0.1 -4.219 0.0140 STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
72 8576 9.9 9.6 0.3 0.3 -1.108 0.3326 STK16 serine/threonine kinase 16
73 9263 2.5 2.4 0.2 0.0 -0.981 0.4244 STK17A serine/threonine kinase 17a
74 7010 2.3 2.3 0.0 0.0 -0.436 0.6866 TEK TEK tyrosine kinase, endothelial
75 7030 9.5 9.5 0.1 0.1 0.636 0.5634 TFE3 transcription factor binding to IGHM enhancer 3
76 7038 3.3 3.8 0.2 0.2 3.201 0.0345 TG thyroglobulin
77 7108 10.5 9.8 0.2 0.2 -5.011 0.0074 TM7SF2 transmembrane 7 superfamily member 2
78 7157 7.9 7.4 0.3 0.5 -1.440 0.2378 TP53 tumor protein p53
79 7170 8.9 9.2 0.2 0.2 2.532 0.0661 TPM3 tropomyosin 3
80 7248 7.0 6.6 0.5 0.0 -1.693 0.2299 TSC1 tuberous sclerosis 1
81 10103 10.3 8.7 0.2 0.7 -3.976 0.0393 TSPAN1 tetraspanin 1
82 7422 8.5 8.5 0.5 0.2 0.009 0.9937 VEGFA vascular endothelial growth factor A
83 7424 6.7 6.8 0.3 0.4 0.285 0.7901 VEGFC vascular endothelial growth factor C
84 7450 5.0 3.7 0.2 0.1 -11.198 0.0004 VWF von Willebrand factor
85 7515 12.9 12.8 0.4 0.2 -0.351 0.7513 XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
86 7525 9.9 9.8 0.1 0.1 -0.554 0.6091 YES1 YES proto-oncogene 1, Src family tyrosine kinase
87 22882 9.6 10.2 0.1 0.3 3.424 0.0581 ZHX2 zinc fingers and homeoboxes 2