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(3s)-3-Cyclopentyl-6-Methyl-7-[(4-Methylpiperazin-1-Yl)sulfonyl]-3,4-Dihydro-2h-1,2,4-Benzothiadiazine 1,1-Dioxide

GeneID Mean_1 Mean_3 StDev_1 StDev_3 T-Statistic p-value SymbolDescription
1 481 10.2 13.5 0.2 0.1 24.123 0.0000 ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
2 51761 2.8 4.2 0.2 0.2 8.068 0.0017 ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
3 9212 8.7 10.0 0.2 0.2 7.824 0.0014 AURKB aurora kinase B
4 920 12.3 12.1 0.1 0.3 -1.157 0.3384 CD4 CD4 molecule
5 925 7.3 6.8 0.1 0.0 -6.573 0.0181 CD8A CD8a molecule
6 81620 13.0 13.5 0.6 0.1 1.278 0.3241 CDT1 chromatin licensing and DNA replication factor 1
7 10521 9.1 9.3 0.1 0.2 1.910 0.1758 DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
8 9188 12.8 13.1 0.1 0.3 1.574 0.2367 DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
9 1654 10.8 11.1 0.1 0.2 2.297 0.0838 DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
10 51428 11.7 11.9 0.2 0.2 1.050 0.3642 DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
11 1655 15.3 15.7 0.1 0.1 4.189 0.0153 DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
12 170506 12.8 12.3 0.0 0.0 -17.154 0.0002 DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36
13 79132 5.9 11.0 0.3 0.3 19.290 0.0001 DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
14 1973 14.2 14.4 0.0 0.1 4.859 0.0152 EIF4A1 eukaryotic translation initiation factor 4A1
15 2158 2.3 2.3 0.0 0.0 0.072 0.9471 F9 coagulation factor IX
16 164045 3.2 2.9 0.9 0.2 -0.572 0.6196 HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
17 3162 7.7 10.0 0.8 0.5 4.350 0.0183 HMOX1 heme oxygenase (decycling) 1
18 3242 3.6 3.5 0.4 0.4 -0.326 0.7608 HPD 4-hydroxyphenylpyruvate dioxygenase
19 8988 2.1 2.6 0.0 0.8 1.008 0.4196 HSPB3 heat shock 27kDa protein 3
20 64135 9.2 10.9 0.2 0.6 5.160 0.0215 IFIH1 interferon induced with helicase C domain 1
21 3456 2.4 4.0 0.1 1.5 1.793 0.2139 IFNB1 interferon, beta 1, fibroblast
22 3458 2.4 2.3 0.1 0.0 -1.013 0.3856 IFNG interferon, gamma
23 282617 2.8 5.4 0.5 1.1 3.665 0.0382 IFNL3 interferon, lambda 3
24 3586 2.3 2.3 0.0 0.0 0.041 0.9698 IL10 interleukin 10
25 3558 2.5 2.4 0.1 0.1 -0.771 0.4998 IL2 interleukin 2
26 3565 2.5 2.6 0.2 0.2 0.616 0.5713 IL4 interleukin 4
27 3569 2.3 2.3 0.0 0.0 -0.440 0.6964 IL6 interleukin 6
28 3630 3.6 4.1 0.4 0.4 1.716 0.1617 INS insulin
29 3661 10.2 10.0 0.2 0.1 -1.730 0.1717 IRF3 interferon regulatory factor 3
30 3704 12.5 12.7 0.0 0.1 6.783 0.0115 ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
31 51497 13.3 13.3 0.1 0.1 -0.641 0.5657 NELFCD negative elongation factor complex member C/D
32 4791 6.8 6.9 0.8 0.2 0.169 0.8799 NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
33 4841 13.3 13.1 0.2 0.3 -1.037 0.3658 NONO non-POU domain containing, octamer-binding
34 10133 7.3 7.4 0.2 0.1 1.199 0.3034 OPTN optineurin
35 10714 10.8 11.2 0.1 0.3 2.421 0.1027 POLD3 polymerase (DNA-directed), delta 3, accessory subunit
36 5478 14.8 15.0 0.1 0.1 2.015 0.1403 PPIA peptidylprolyl isomerase A (cyclophilin A)
37 9677 4.7 5.2 0.2 0.1 3.033 0.0521 PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
38 10594 12.6 12.4 0.1 0.0 -2.239 0.1318 PRPF8 pre-mRNA processing factor 8
39 5894 11.5 11.4 0.2 0.1 -0.477 0.6613 RAF1 Raf-1 proto-oncogene, serine/threonine kinase
40 5923 3.0 2.3 1.2 0.1 -0.992 0.4255 RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
41 6037 2.5 2.2 0.4 0.0 -0.981 0.4296 RNASE3 ribonuclease, RNase A family, 3
42 10044 3.2 2.9 0.8 0.1 -0.661 0.5745 SH2D3C SH2 domain containing 3C
43 11136 2.3 2.3 0.0 0.0 -0.170 0.8757 SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
44 8467 8.6 8.9 0.2 0.1 3.056 0.0508 SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
45 6772 8.8 11.3 0.2 0.2 14.558 0.0002 STAT1 signal transducer and activator of transcription 1, 91kDa
46 6903 9.7 10.0 0.1 0.1 3.634 0.0268 TBCC tubulin folding cofactor C
47 148022 8.8 8.9 0.4 0.5 0.159 0.8818 TICAM1 toll-like receptor adaptor molecule 1
48 7097 2.9 5.0 0.8 0.9 2.980 0.0417 TLR2 toll-like receptor 2
49 7098 2.4 2.9 0.0 0.3 2.782 0.1079 TLR3 toll-like receptor 3
50 7099 2.6 3.1 0.2 0.4 1.745 0.1872 TLR4 toll-like receptor 4
51 51284 2.6 2.5 0.2 0.3 -0.550 0.6119 TLR7 toll-like receptor 7
52 7124 3.9 4.1 2.4 0.7 0.111 0.9206 TNF tumor necrosis factor
53 7157 7.9 7.4 0.3 0.5 -1.440 0.2378 TP53 tumor protein p53
54 5976 12.3 12.3 0.0 0.2 0.011 0.9925 UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)