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Gefitinib

GeneID Mean_1 Mean_3 StDev_1 StDev_3 T-Statistic p-value SymbolDescription
1 19 3.0 2.4 0.6 0.1 -1.605 0.2442 ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
2 9429 2.8 6.4 0.5 0.3 11.391 0.0013 ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
3 196 9.6 8.4 0.3 0.2 -6.697 0.0045 AHR aryl hydrocarbon receptor
4 231 2.7 5.8 0.3 0.1 16.078 0.0023 AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
5 238 2.5 2.5 0.1 0.1 0.197 0.8553 ALK anaplastic lymphoma receptor tyrosine kinase
6 481 10.2 13.5 0.2 0.1 24.123 0.0000 ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
7 51761 2.8 4.2 0.2 0.2 8.068 0.0017 ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
8 9212 8.7 10.0 0.2 0.2 7.824 0.0014 AURKB aurora kinase B
9 581 9.5 9.5 0.3 0.1 -0.257 0.8169 BAX BCL2-associated X protein
10 596 10.3 10.3 0.2 0.1 0.739 0.5268 BCL2 B-cell CLL/lymphoma 2
11 78996 9.9 11.0 0.2 0.1 9.881 0.0048 C7orf49 chromosome 7 open reading frame 49
12 836 8.2 8.0 0.3 0.2 -1.211 0.3082 CASP3 caspase 3, apoptosis-related cysteine peptidase
13 842 8.6 7.7 0.1 0.6 -2.444 0.1304 CASP9 caspase 9, apoptosis-related cysteine peptidase
14 57332 9.5 9.0 0.6 0.3 -1.117 0.3492 CBX8 chromobox homolog 8
15 891 11.3 12.0 0.1 0.2 4.535 0.0280 CCNB1 cyclin B1
16 55536 9.5 8.5 0.2 0.1 -6.800 0.0050 CDCA7L cell division cycle associated 7-like
17 1000 3.2 3.2 0.4 0.1 0.188 0.8677 CDH2 cadherin 2, type 1, N-cadherin (neuronal)
18 1029 6.0 6.5 0.4 0.0 2.330 0.1427 CDKN2A cyclin-dependent kinase inhibitor 2A
19 81620 13.0 13.5 0.6 0.1 1.278 0.3241 CDT1 chromatin licensing and DNA replication factor 1
20 1084 2.6 3.0 0.3 0.7 0.902 0.4445 CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
21 83548 10.1 10.1 0.0 0.2 0.698 0.5574 COG3 component of oligomeric golgi complex 3
22 114757 13.4 13.0 0.1 0.2 -2.755 0.0760 CYGB cytoglobin
23 1558 2.2 2.8 0.0 0.6 1.477 0.2775 CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
24 4921 2.6 2.9 0.4 0.4 0.964 0.3899 DDR2 discoidin domain receptor tyrosine kinase 2
25 1950 2.3 2.4 0.0 0.1 1.016 0.4144 EGF epidermal growth factor
26 1956 2.9 3.3 0.2 0.1 3.112 0.0782 EGFR epidermal growth factor receptor
27 1978 13.9 12.8 0.8 0.1 -2.355 0.1388 EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
28 1999 10.5 10.5 0.1 0.7 0.018 0.9875 ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
29 27436 11.9 12.3 0.1 0.0 4.717 0.0311 EML4 echinoderm microtubule associated protein like 4
30 2048 5.7 5.8 0.3 0.2 0.700 0.5288 EPHB2 EPH receptor B2
31 2064 9.7 9.0 0.4 0.3 -2.344 0.0865 ERBB2 erb-b2 receptor tyrosine kinase 2
32 2065 9.6 9.3 0.1 0.2 -2.412 0.0886 ERBB3 erb-b2 receptor tyrosine kinase 3
33 2066 7.9 5.6 0.2 0.3 -11.036 0.0005 ERBB4 erb-b2 receptor tyrosine kinase 4
34 2099 11.4 9.4 0.1 0.2 -16.793 0.0003 ESR1 estrogen receptor 1
35 2109 14.1 14.3 0.2 0.2 1.350 0.2482 ETFB electron-transfer-flavoprotein, beta polypeptide
36 2258 4.8 6.2 0.4 0.4 4.282 0.0135 FGF13 fibroblast growth factor 13
37 2321 2.4 2.5 0.1 0.1 0.409 0.7102 FLT1 fms-related tyrosine kinase 1
38 2335 4.0 3.7 1.6 0.6 -0.245 0.8247 FN1 fibronectin 1
39 51053 12.1 12.6 0.3 0.4 1.716 0.1624 GMNN geminin, DNA replication inhibitor
40 2996 2.3 2.3 0.0 0.0 -0.435 0.6861 GYPE glycophorin E (MNS blood group)
41 3014 13.3 13.7 0.1 0.2 2.466 0.0809 H2AFX H2A histone family, member X
42 3265 10.7 10.7 0.2 0.4 -0.278 0.8001 HRAS Harvey rat sarcoma viral oncogene homolog
43 3292 8.9 8.4 0.1 0.1 -8.250 0.0016 HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
44 3480 12.9 12.8 0.3 0.2 -0.296 0.7828 IGF1R insulin-like growth factor 1 receptor
45 3484 2.4 2.2 0.2 0.0 -0.937 0.4466 IGFBP1 insulin-like growth factor binding protein 1
46 3486 6.3 5.5 0.8 1.0 -1.214 0.2937 IGFBP3 insulin-like growth factor binding protein 3
47 3569 2.3 2.3 0.0 0.0 -0.440 0.6964 IL6 interleukin 6
48 3630 3.6 4.1 0.4 0.4 1.716 0.1617 INS insulin
49 3791 2.4 2.3 0.0 0.1 -0.496 0.6472 KDR kinase insert domain receptor
50 4214 11.6 11.1 0.1 0.1 -4.921 0.0154 MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
51 5595 8.9 9.2 0.3 0.1 1.920 0.1525 MAPK3 mitogen-activated protein kinase 3
52 4137 11.1 11.1 0.2 0.1 -0.578 0.6155 MAPT microtubule-associated protein tau
53 4233 9.9 11.6 0.1 0.1 28.016 0.0001 MET MET proto-oncogene, receptor tyrosine kinase
54 2475 8.9 9.1 0.0 0.1 3.319 0.0559 MTOR mechanistic target of rapamycin (serine/threonine kinase)
55 4609 8.9 8.0 0.4 0.6 -2.174 0.1053 MYC v-myc avian myelocytomatosis viral oncogene homolog
56 4691 15.3 15.0 0.0 0.3 -1.484 0.2676 NCL nucleolin
57 4780 3.0 4.4 0.8 2.1 1.080 0.3704 NFE2L2 nuclear factor, erythroid 2-like 2
58 7080 2.6 2.4 0.3 0.1 -1.110 0.3776 NKX2-1 NK2 homeobox 1
59 3084 2.6 2.6 0.2 0.1 -0.234 0.8278 NRG1 neuregulin 1
60 27065 2.1 2.1 0.0 0.0 0.372 0.7400 NSG1 neuron specific gene family member 1
61 10038 11.1 11.8 0.3 0.3 3.112 0.0358 PARP2 poly (ADP-ribose) polymerase 2
62 5077 2.9 3.2 0.4 0.3 1.051 0.3563 PAX3 paired box 3
63 5111 12.0 13.1 0.2 0.4 4.276 0.0250 PCNA proliferating cell nuclear antigen
64 255738 2.3 2.4 0.0 0.2 1.182 0.3583 PCSK9 proprotein convertase subtilisin/kexin type 9
65 283871 9.2 9.5 0.2 0.4 1.469 0.2460 PGP phosphoglycolate phosphatase
66 5241 10.2 11.5 0.2 0.1 9.929 0.0013 PGR progesterone receptor
67 5293 3.8 3.0 0.6 0.2 -2.016 0.1586 PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
68 5292 8.3 8.4 0.2 0.4 0.345 0.7554 PIM1 Pim-1 proto-oncogene, serine/threonine kinase
69 55558 11.7 11.8 0.2 0.2 0.458 0.6717 PLXNA3 plexin A3
70 57804 14.6 13.8 0.3 0.4 -2.989 0.0453 POLD4 polymerase (DNA-directed), delta 4, accessory subunit
71 5443 3.0 3.3 0.4 0.6 0.757 0.5017 POMC proopiomelanocortin
72 5468 2.3 4.0 0.0 0.5 5.713 0.0291 PPARG peroxisome proliferator-activated receptor gamma
73 7001 12.0 12.1 0.1 0.0 3.370 0.0339 PRDX2 peroxiredoxin 2
74 5728 10.1 9.8 0.0 0.1 -3.208 0.0714 PTEN phosphatase and tensin homolog
75 2185 9.1 8.2 0.0 0.4 -4.284 0.0472 PTK2B protein tyrosine kinase 2 beta
76 5894 11.5 11.4 0.2 0.1 -0.477 0.6613 RAF1 Raf-1 proto-oncogene, serine/threonine kinase
77 5923 3.0 2.3 1.2 0.1 -0.992 0.4255 RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
78 10535 13.6 13.6 0.1 0.1 0.277 0.7967 RNASEH2A ribonuclease H2, subunit A
79 6098 4.4 2.6 0.3 0.5 -5.609 0.0063 ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
80 6185 12.8 13.3 0.1 0.1 6.250 0.0058 RPN2 ribophorin II
81 677775 7.5 7.5 0.1 0.1 -0.090 0.9327 SCARNA5 small Cajal body-specific RNA 5
82 29072 8.7 8.7 0.0 0.0 0.189 0.8593 SETD2 SET domain containing 2
83 9644 3.4 2.9 0.4 0.4 -1.640 0.1765 SH3PXD2A SH3 and PX domains 2A
84 6581 2.4 2.4 0.0 0.1 0.029 0.9782 SLC22A3 solute carrier family 22 (organic cation transporter), member 3
85 9748 9.5 9.6 0.1 0.2 0.590 0.6044 SLK STE20-like kinase
86 9126 11.5 11.9 0.1 0.2 2.424 0.0778 SMC3 structural maintenance of chromosomes 3
87 6714 6.5 7.6 0.1 0.1 13.718 0.0002 SRC SRC proto-oncogene, non-receptor tyrosine kinase
88 6754 2.5 2.5 0.3 0.3 -0.160 0.8809 SSTR4 somatostatin receptor 4
89 6774 7.9 7.4 0.2 0.1 -4.219 0.0140 STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
90 6865 6.3 6.3 0.2 0.0 0.372 0.7439 TACR2 tachykinin receptor 2
91 7030 9.5 9.5 0.1 0.1 0.636 0.5634 TFE3 transcription factor binding to IGHM enhancer 3
92 7157 7.9 7.4 0.3 0.5 -1.440 0.2378 TP53 tumor protein p53
93 7422 8.5 8.5 0.5 0.2 0.009 0.9937 VEGFA vascular endothelial growth factor A
94 7431 4.9 6.7 0.5 0.1 6.548 0.0153 VIM vimentin
95 7525 9.9 9.8 0.1 0.1 -0.554 0.6091 YES1 YES proto-oncogene 1, Src family tyrosine kinase