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Imatinib mesylate

GeneID Mean_1 Mean_3 StDev_1 StDev_3 T-Statistic p-value SymbolDescription
1 19 3.0 2.4 0.6 0.1 -1.605 0.2442 ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
2 9429 2.8 6.4 0.5 0.3 11.391 0.0013 ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
3 53 7.1 6.8 0.3 0.3 -1.081 0.3404 ACP2 acid phosphatase 2, lysosomal
4 183 2.4 2.4 0.1 0.0 -1.120 0.3647 AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
5 196 9.6 8.4 0.3 0.2 -6.697 0.0045 AHR aryl hydrocarbon receptor
6 213 3.2 2.8 0.4 0.5 -1.148 0.3190 ALB albumin
7 238 2.5 2.5 0.1 0.1 0.197 0.8553 ALK anaplastic lymphoma receptor tyrosine kinase
8 55107 2.6 2.8 0.4 0.6 0.305 0.7783 ANO1 anoctamin 1, calcium activated chloride channel
9 351 10.8 10.5 0.1 0.3 -1.679 0.1960 APP amyloid beta (A4) precursor protein
10 9138 6.7 6.9 0.4 0.1 0.643 0.5800 ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
11 347527 2.5 2.8 0.1 0.4 1.098 0.3784 ARSH arylsulfatase family, member H
12 443 2.4 2.6 0.0 0.2 1.598 0.2367 ASPA aspartoacylase
13 1822 10.5 10.7 0.2 0.1 1.880 0.1334 ATN1 atrophin 1
14 51761 2.8 4.2 0.2 0.2 8.068 0.0017 ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
15 9212 8.7 10.0 0.2 0.2 7.824 0.0014 AURKB aurora kinase B
16 6795 2.3 2.2 0.1 0.0 -0.879 0.4595 AURKC aurora kinase C
17 158835 3.4 2.3 1.9 0.0 -0.989 0.4269 AWAT2 acyl-CoA wax alcohol acyltransferase 2
18 27241 6.8 6.8 0.6 0.7 0.060 0.9553 BBS9 Bardet-Biedl syndrome 9
19 596 10.3 10.3 0.2 0.1 0.739 0.5268 BCL2 B-cell CLL/lymphoma 2
20 598 8.1 7.7 0.2 0.1 -2.960 0.0676 BCL2L1 BCL2-like 1
21 613 9.2 9.2 0.2 0.1 -0.129 0.9051 BCR breakpoint cluster region
22 8678 12.2 11.6 0.1 0.1 -10.006 0.0008 BECN1 beclin 1, autophagy related
23 672 9.9 10.0 0.0 0.4 0.374 0.7433 BRCA1 breast cancer 1, early onset
24 83990 10.5 11.4 0.3 0.7 2.104 0.1282 BRIP1 BRCA1 interacting protein C-terminal helicase 1
25 695 2.9 3.1 0.0 1.2 0.253 0.8241 BTK Bruton agammaglobulinemia tyrosine kinase
26 78996 9.9 11.0 0.2 0.1 9.881 0.0048 C7orf49 chromosome 7 open reading frame 49
27 836 8.2 8.0 0.3 0.2 -1.211 0.3082 CASP3 caspase 3, apoptosis-related cysteine peptidase
28 841 5.6 6.3 0.3 0.2 2.697 0.0646 CASP8 caspase 8, apoptosis-related cysteine peptidase
29 842 8.6 7.7 0.1 0.6 -2.444 0.1304 CASP9 caspase 9, apoptosis-related cysteine peptidase
30 947 2.6 2.4 0.1 0.1 -2.834 0.0480 CD34 CD34 molecule
31 920 12.3 12.1 0.1 0.3 -1.157 0.3384 CD4 CD4 molecule
32 960 13.9 11.7 0.4 0.2 -8.327 0.0057 CD44 CD44 molecule (Indian blood group)
33 925 7.3 6.8 0.1 0.0 -6.573 0.0181 CD8A CD8a molecule
34 1000 3.2 3.2 0.4 0.1 0.188 0.8677 CDH2 cadherin 2, type 1, N-cadherin (neuronal)
35 1019 14.3 14.4 0.2 0.1 0.678 0.5498 CDK4 cyclin-dependent kinase 4
36 1029 6.0 6.5 0.4 0.0 2.330 0.1427 CDKN2A cyclin-dependent kinase inhibitor 2A
37 81620 13.0 13.5 0.6 0.1 1.278 0.3241 CDT1 chromatin licensing and DNA replication factor 1
38 634 3.2 3.3 0.5 0.1 0.339 0.7645 CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
39 10153 11.0 11.1 0.2 0.1 0.563 0.6055 CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
40 1268 2.2 2.4 0.0 0.1 1.848 0.2050 CNR1 cannabinoid receptor 1 (brain)
41 8506 6.1 6.0 0.1 0.2 -0.537 0.6258 CNTNAP1 contactin associated protein 1
42 83548 10.1 10.1 0.0 0.2 0.698 0.5574 COG3 component of oligomeric golgi complex 3
43 341947 2.8 3.0 0.2 0.3 1.353 0.2543 COX8C cytochrome c oxidase subunit VIIIC
44 1378 2.7 2.3 0.8 0.0 -0.979 0.4301 CR1 complement component (3b/4b) receptor 1 (Knops blood group)
45 1399 6.7 7.6 0.1 0.2 6.834 0.0036 CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
46 1435 4.2 4.2 0.0 0.1 -0.879 0.4638 CSF1 colony stimulating factor 1 (macrophage)
47 1436 3.7 2.9 0.1 0.4 -3.787 0.0406 CSF1R colony stimulating factor 1 receptor
48 1437 2.3 2.3 0.0 0.0 0.420 0.7020 CSF2 colony stimulating factor 2 (granulocyte-macrophage)
49 1440 2.7 2.6 0.2 0.1 -0.180 0.8679 CSF3 colony stimulating factor 3 (granulocyte)
50 6387 7.9 8.5 0.3 0.3 2.040 0.1110 CXCL12 chemokine (C-X-C motif) ligand 12
51 54205 10.8 10.8 0.4 0.3 0.041 0.9690 CYCS cytochrome c, somatic
52 114757 13.4 13.0 0.1 0.2 -2.755 0.0760 CYGB cytoglobin
53 1558 2.2 2.8 0.0 0.6 1.477 0.2775 CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
54 4921 2.6 2.9 0.4 0.4 0.964 0.3899 DDR2 discoidin domain receptor tyrosine kinase 2
55 1674 8.3 7.9 0.3 0.1 -2.309 0.1312 DES desmin
56 1950 2.3 2.4 0.0 0.1 1.016 0.4144 EGF epidermal growth factor
57 1956 2.9 3.3 0.2 0.1 3.112 0.0782 EGFR epidermal growth factor receptor
58 1999 10.5 10.5 0.1 0.7 0.018 0.9875 ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
59 2048 5.7 5.8 0.3 0.2 0.700 0.5288 EPHB2 EPH receptor B2
60 2064 9.7 9.0 0.4 0.3 -2.344 0.0865 ERBB2 erb-b2 receptor tyrosine kinase 2
61 2120 7.0 6.7 0.2 0.2 -2.086 0.1070 ETV6 ets variant 6
62 2125 11.0 10.9 0.1 0.1 -0.593 0.5968 EVPL envoplakin
63 2158 2.3 2.3 0.0 0.0 0.072 0.9471 F9 coagulation factor IX
64 144717 7.2 7.6 0.2 0.2 2.499 0.0694 FAM109A family with sequence similarity 109, member A
65 2258 4.8 6.2 0.4 0.4 4.282 0.0135 FGF13 fibroblast growth factor 13
66 2321 2.4 2.5 0.1 0.1 0.409 0.7102 FLT1 fms-related tyrosine kinase 1
67 2335 4.0 3.7 1.6 0.6 -0.245 0.8247 FN1 fibronectin 1
68 2309 11.3 10.7 0.1 0.2 -5.665 0.0060 FOXO3 forkhead box O3
69 9837 11.7 12.2 0.2 0.4 2.240 0.1160 GINS1 GINS complex subunit 1 (Psf1 homolog)
70 11318 3.8 3.4 0.7 1.1 -0.512 0.6414 GPR182 G protein-coupled receptor 182
71 2876 3.7 3.9 0.4 0.6 0.580 0.5999 GPX1 glutathione peroxidase 1
72 3014 13.3 13.7 0.1 0.2 2.466 0.0809 H2AFX H2A histone family, member X
73 3043 2.4 2.4 0.0 0.0 0.209 0.8450 HBB hemoglobin, beta
74 3162 7.7 10.0 0.8 0.5 4.350 0.0183 HMOX1 heme oxygenase (decycling) 1
75 3242 3.6 3.5 0.4 0.4 -0.326 0.7608 HPD 4-hydroxyphenylpyruvate dioxygenase
76 3265 10.7 10.7 0.2 0.4 -0.278 0.8001 HRAS Harvey rat sarcoma viral oncogene homolog
77 3292 8.9 8.4 0.1 0.1 -8.250 0.0016 HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
78 3417 10.4 11.1 0.1 0.0 9.035 0.0115 IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
79 3458 2.4 2.3 0.1 0.0 -1.013 0.3856 IFNG interferon, gamma
80 3480 12.9 12.8 0.3 0.2 -0.296 0.7828 IGF1R insulin-like growth factor 1 receptor
81 3484 2.4 2.2 0.2 0.0 -0.937 0.4466 IGFBP1 insulin-like growth factor binding protein 1
82 10320 2.4 2.4 0.1 0.1 -0.009 0.9936 IKZF1 IKAROS family zinc finger 1 (Ikaros)
83 22806 2.4 3.9 0.0 1.3 1.979 0.1862 IKZF3 IKAROS family zinc finger 3 (Aiolos)
84 3593 2.5 2.7 0.1 0.2 1.200 0.3319 IL12B interleukin 12B
85 3558 2.5 2.4 0.1 0.1 -0.771 0.4998 IL2 interleukin 2
86 246778 4.9 5.3 0.2 0.5 1.254 0.3133 IL27 interleukin 27
87 3559 2.3 2.3 0.1 0.0 -1.010 0.4164 IL2RA interleukin 2 receptor, alpha
88 3562 2.5 2.6 0.1 0.2 0.361 0.7433 IL3 interleukin 3
89 3565 2.5 2.6 0.2 0.2 0.616 0.5713 IL4 interleukin 4
90 3567 3.3 3.3 0.1 0.9 0.064 0.9547 IL5 interleukin 5
91 3569 2.3 2.3 0.0 0.0 -0.440 0.6964 IL6 interleukin 6
92 3630 3.6 4.1 0.4 0.4 1.716 0.1617 INS insulin
93 3643 8.3 9.3 0.1 0.2 8.564 0.0056 INSR insulin receptor
94 3717 7.8 9.0 0.2 0.4 5.183 0.0187 JAK2 Janus kinase 2
95 3791 2.4 2.3 0.0 0.1 -0.496 0.6472 KDR kinase insert domain receptor
96 3815 2.3 2.3 0.1 0.0 -0.184 0.8629 KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
97 3854 2.3 4.2 0.1 1.2 2.630 0.1181 KRT6B keratin 6B, type II
98 3939 13.5 13.5 0.2 0.3 0.040 0.9697 LDHA lactate dehydrogenase A
99 4214 11.6 11.1 0.1 0.1 -4.921 0.0154 MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
100 5871 7.3 7.0 0.2 0.2 -1.543 0.1986 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
101 1432 7.8 7.5 0.3 0.2 -1.540 0.2107 MAPK14 mitogen-activated protein kinase 14
102 5595 8.9 9.2 0.3 0.1 1.920 0.1525 MAPK3 mitogen-activated protein kinase 3
103 4170 10.3 10.6 0.4 0.3 1.170 0.3075 MCL1 myeloid cell leukemia 1
104 4233 9.9 11.6 0.1 0.1 28.016 0.0001 MET MET proto-oncogene, receptor tyrosine kinase
105 4313 2.5 2.6 0.1 0.2 0.907 0.4292 MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
106 4353 2.7 2.3 0.3 0.0 -2.005 0.1812 MPO myeloperoxidase
107 4360 2.5 2.7 0.1 0.3 1.239 0.3031 MRC1 mannose receptor, C type 1
108 2475 8.9 9.1 0.0 0.1 3.319 0.0559 MTOR mechanistic target of rapamycin (serine/threonine kinase)
109 4609 8.9 8.0 0.4 0.6 -2.174 0.1053 MYC v-myc avian myelocytomatosis viral oncogene homolog
110 4790 10.2 10.5 0.0 0.0 12.358 0.0018 NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
111 4795 12.8 12.5 0.3 0.1 -1.631 0.2349 NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
112 9971 2.4 2.5 0.0 0.2 0.992 0.4216 NR1H4 nuclear receptor subfamily 1, group H, member 4
113 4893 11.2 11.1 0.2 0.1 -0.175 0.8734 NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
114 27065 2.1 2.1 0.0 0.0 0.372 0.7400 NSG1 neuron specific gene family member 1
115 10133 7.3 7.4 0.2 0.1 1.199 0.3034 OPTN optineurin
116 10038 11.1 11.8 0.3 0.3 3.112 0.0358 PARP2 poly (ADP-ribose) polymerase 2
117 5077 2.9 3.2 0.4 0.3 1.051 0.3563 PAX3 paired box 3
118 5111 12.0 13.1 0.2 0.4 4.276 0.0250 PCNA proliferating cell nuclear antigen
119 5154 6.2 7.5 0.3 0.4 4.563 0.0115 PDGFA platelet-derived growth factor alpha polypeptide
120 5156 2.3 2.3 0.0 0.0 0.365 0.7443 PDGFRA platelet-derived growth factor receptor, alpha polypeptide
121 5159 2.3 2.3 0.0 0.0 0.990 0.3792 PDGFRB platelet-derived growth factor receptor, beta polypeptide
122 80055 4.9 5.1 0.5 0.3 0.618 0.5733 PGAP1 post-GPI attachment to proteins 1
123 283871 9.2 9.5 0.2 0.4 1.469 0.2460 PGP phosphoglycolate phosphatase
124 5266 2.9 3.5 0.8 0.3 1.171 0.3403 PI3 peptidase inhibitor 3, skin-derived
125 55558 11.7 11.8 0.2 0.2 0.458 0.6717 PLXNA3 plexin A3
126 57804 14.6 13.8 0.3 0.4 -2.989 0.0453 POLD4 polymerase (DNA-directed), delta 4, accessory subunit
127 728378 13.3 13.4 0.3 0.1 0.452 0.6847 POTEF POTE ankyrin domain family, member F
128 5468 2.3 4.0 0.0 0.5 5.713 0.0291 PPARG peroxisome proliferator-activated receptor gamma
129 7001 12.0 12.1 0.1 0.0 3.370 0.0339 PRDX2 peroxiredoxin 2
130 112476 10.8 10.5 0.2 0.2 -1.846 0.1438 PRRT2 proline-rich transmembrane protein 2
131 83886 6.2 6.5 0.4 0.5 0.724 0.5093 PRSS27 protease, serine 27
132 5728 10.1 9.8 0.0 0.1 -3.208 0.0714 PTEN phosphatase and tensin homolog
133 2185 9.1 8.2 0.0 0.4 -4.284 0.0472 PTK2B protein tyrosine kinase 2 beta
134 5788 2.9 3.0 0.2 0.4 0.315 0.7747 PTPRC protein tyrosine phosphatase, receptor type, C
135 5893 7.5 7.3 0.4 0.1 -0.678 0.5624 RAD52 RAD52 homolog (S. cerevisiae)
136 5894 11.5 11.4 0.2 0.1 -0.477 0.6613 RAF1 Raf-1 proto-oncogene, serine/threonine kinase
137 6006 4.4 4.1 0.5 0.3 -0.751 0.5024 RHCE Rh blood group, CcEe antigens
138 6010 2.6 3.5 0.3 0.4 3.430 0.0353 RHO rhodopsin
139 10535 13.6 13.6 0.1 0.1 0.277 0.7967 RNASEH2A ribonuclease H2, subunit A
140 6093 9.3 9.2 0.1 0.2 -0.888 0.4381 ROCK1 Rho-associated, coiled-coil containing protein kinase 1
141 6098 4.4 2.6 0.3 0.5 -5.609 0.0063 ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
142 6198 12.0 12.2 0.2 0.2 1.256 0.2780 RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
143 6238 9.5 9.5 0.1 0.1 0.013 0.9902 RRBP1 ribosome binding protein 1
144 861 6.3 7.2 0.3 0.3 4.027 0.0158 RUNX1 runt-related transcription factor 1
145 6271 5.9 4.2 0.5 0.5 -4.044 0.0156 S100A1 S100 calcium binding protein A1
146 9733 10.0 10.4 0.2 0.1 3.199 0.0713 SART3 squamous cell carcinoma antigen recognized by T cells 3
147 29072 8.7 8.7 0.0 0.0 0.189 0.8593 SETD2 SET domain containing 2
148 27352 6.3 6.1 0.2 0.4 -0.782 0.4914 SGSM3 small G protein signaling modulator 3
149 9644 3.4 2.9 0.4 0.4 -1.640 0.1765 SH3PXD2A SH3 and PX domains 2A
150 23411 8.8 9.8 0.2 0.3 4.479 0.0155 SIRT1 sirtuin 1
151 6580 2.7 2.8 0.2 0.3 0.798 0.4724 SLC22A1 solute carrier family 22 (organic cation transporter), member 1
152 6581 2.4 2.4 0.0 0.1 0.029 0.9782 SLC22A3 solute carrier family 22 (organic cation transporter), member 3
153 6579 2.5 2.7 0.1 0.3 1.041 0.3934 SLCO1A2 solute carrier organic anion transporter family, member 1A2
154 23583 9.9 9.9 0.1 0.0 0.634 0.5814 SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
155 6638 2.3 2.3 0.0 0.0 0.375 0.7343 SNRPN small nuclear ribonucleoprotein polypeptide N
156 6652 8.6 9.4 0.2 0.1 8.100 0.0088 SORD sorbitol dehydrogenase
157 6714 6.5 7.6 0.1 0.1 13.718 0.0002 SRC SRC proto-oncogene, non-receptor tyrosine kinase
158 6772 8.8 11.3 0.2 0.2 14.558 0.0002 STAT1 signal transducer and activator of transcription 1, 91kDa
159 6774 7.9 7.4 0.2 0.1 -4.219 0.0140 STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
160 6850 9.3 8.9 0.1 0.2 -4.322 0.0243 SYK spleen tyrosine kinase
161 6865 6.3 6.3 0.2 0.0 0.372 0.7439 TACR2 tachykinin receptor 2
162 6949 9.2 9.8 0.1 0.4 2.574 0.1186 TCOF1 Treacher Collins-Franceschetti syndrome 1
163 55775 11.6 11.9 0.0 0.1 4.751 0.0210 TDP1 tyrosyl-DNA phosphodiesterase 1
164 11011 10.3 10.3 0.1 0.1 0.133 0.9020 TLK2 tousled-like kinase 2
165 7124 3.9 4.1 2.4 0.7 0.111 0.9206 TNF tumor necrosis factor
166 7157 7.9 7.4 0.3 0.5 -1.440 0.2378 TP53 tumor protein p53
167 7170 8.9 9.2 0.2 0.2 2.532 0.0661 TPM3 tropomyosin 3
168 23430 3.5 2.3 2.2 0.1 -0.976 0.4319 TPSD1 tryptase delta 1
169 7187 6.6 6.6 0.3 0.3 0.039 0.9711 TRAF3 TNF receptor-associated factor 3
170 83696 11.2 10.8 0.1 0.4 -1.557 0.2423 TRAPPC9 trafficking protein particle complex 9
171 7248 7.0 6.6 0.5 0.0 -1.693 0.2299 TSC1 tuberous sclerosis 1
172 7253 2.2 2.2 0.0 0.0 -0.897 0.4388 TSHR thyroid stimulating hormone receptor
173 8615 12.1 11.6 0.1 0.1 -7.027 0.0028 USO1 USO1 vesicle transport factor
174 7422 8.5 8.5 0.5 0.2 0.009 0.9937 VEGFA vascular endothelial growth factor A
175 7431 4.9 6.7 0.5 0.1 6.548 0.0153 VIM vimentin
176 7490 2.4 2.3 0.1 0.0 -1.205 0.2991 WT1 Wilms tumor 1
177 331 9.5 9.9 0.1 0.2 2.825 0.0546 XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
178 7532 13.5 13.9 0.1 0.1 5.532 0.0125 YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
179 22882 9.6 10.2 0.1 0.3 3.424 0.0581 ZHX2 zinc fingers and homeoboxes 2