Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | GE_agg.GE_agg.cls#LTED_versus_MCF7p.GE_agg.cls#LTED_versus_MCF7p_repos |
| Phenotype | GE_agg.cls#LTED_versus_MCF7p_repos |
| Upregulated in class | LTED |
| GeneSet | ZIPRASIDONE |
| Enrichment Score (ES) | 0.5036405 |
| Normalized Enrichment Score (NES) | 1.2768694 |
| Nominal p-value | 0.1781076 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | 3358 | NA | HTR2C Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled | 136 | 1.570 | 0.1872 | Yes |
| 2 | 3363 | NA | HTR7 Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled | 748 | 0.652 | 0.2397 | Yes |
| 3 | 1815 | NA | DRD4 Entrez, Source | dopamine receptor D4 | 912 | 0.580 | 0.3038 | Yes |
| 4 | 1128 | NA | CHRM1 Entrez, Source | cholinergic receptor, muscarinic 1 | 1231 | 0.495 | 0.3503 | Yes |
| 5 | 1814 | NA | DRD3 Entrez, Source | dopamine receptor D3 | 1426 | 0.453 | 0.3972 | Yes |
| 6 | 146 | NA | ADRA1D Entrez, Source | adrenoceptor alpha 1D | 1431 | 0.451 | 0.4526 | Yes |
| 7 | 3350 | NA | HTR1A Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled | 2194 | 0.344 | 0.4603 | Yes |
| 8 | 3757 | NA | KCNH2 Entrez, Source | potassium channel, voltage gated eag related subfamily H, member 2 | 2639 | 0.291 | 0.4760 | Yes |
| 9 | 1812 | NA | DRD1 Entrez, Source | dopamine receptor D1 | 3023 | 0.255 | 0.4900 | Yes |
| 10 | 147 | NA | ADRA1B Entrez, Source | adrenoceptor alpha 1B | 3341 | 0.228 | 0.5036 | Yes |
| 11 | 367 | NA | AR Entrez, Source | androgen receptor | 4147 | 0.175 | 0.4886 | No |
| 12 | 3269 | NA | HRH1 Entrez, Source | histamine receptor H1 | 4437 | 0.158 | 0.4949 | No |
| 13 | 6532 | NA | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter), member 4 | 6572 | 0.077 | 0.4073 | No |
| 14 | 10919 | NA | EHMT2 Entrez, Source | euchromatic histone-lysine N-methyltransferase 2 | 6620 | 0.076 | 0.4145 | No |
| 15 | 3352 | NA | HTR1D Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled | 7023 | 0.064 | 0.4040 | No |
| 16 | 196 | NA | AHR Entrez, Source | aryl hydrocarbon receptor | 8000 | 0.043 | 0.3649 | No |
| 17 | 1813 | NA | DRD2 Entrez, Source | dopamine receptor D2 | 9209 | 0.022 | 0.3126 | No |
| 18 | 3351 | NA | HTR1B Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled | 12330 | -0.025 | 0.1737 | No |
| 19 | 55775 | NA | TDP1 Entrez, Source | tyrosyl-DNA phosphodiesterase 1 | 13012 | -0.038 | 0.1474 | No |
| 20 | 148 | NA | ADRA1A Entrez, Source | adrenoceptor alpha 1A | 16506 | -0.127 | 0.0041 | No |
| 21 | 3354 | NA | HTR1E Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled | 19025 | -0.253 | -0.0793 | No |
| 22 | 3356 | NA | HTR2A Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled | 19605 | -0.304 | -0.0683 | No |
| 23 | 2908 | NA | NR3C1 Entrez, Source | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 21034 | -0.516 | -0.0697 | No |
| 24 | 3362 | NA | HTR6 Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled | 21682 | -0.922 | 0.0144 | No |
