Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | GE_agg.GE_agg.cls#LTED_versus_MCF7p.GE_agg.cls#LTED_versus_MCF7p_repos |
| Phenotype | GE_agg.cls#LTED_versus_MCF7p_repos |
| Upregulated in class | MCF7p |
| GeneSet | TROGLITAZONE |
| Enrichment Score (ES) | -0.53223723 |
| Normalized Enrichment Score (NES) | -1.3328376 |
| Nominal p-value | 0.11088296 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | 2099 | NA | ESR1 Entrez, Source | estrogen receptor 1 | 602 | 0.736 | 0.0733 | No |
| 2 | 1544 | NA | CYP1A2 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 2 | 1159 | 0.511 | 0.1179 | No |
| 3 | 140 | NA | ADORA3 Entrez, Source | adenosine A3 receptor | 2484 | 0.309 | 0.1000 | No |
| 4 | 4780 | NA | NFE2L2 Entrez, Source | nuclear factor, erythroid 2-like 2 | 3546 | 0.213 | 0.0809 | No |
| 5 | 7157 | NA | TP53 Entrez, Source | tumor protein p53 | 5673 | 0.106 | -0.0013 | No |
| 6 | 6916 | NA | TBXAS1 Entrez, Source | thromboxane A synthase 1 (platelet) | 7506 | 0.052 | -0.0775 | No |
| 7 | 1565 | NA | CYP2D6 Entrez, Source | cytochrome P450, family 2, subfamily D, polypeptide 6 | 9172 | 0.023 | -0.1501 | No |
| 8 | 1559 | NA | CYP2C9 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 9 | 9513 | 0.017 | -0.1632 | No |
| 9 | 1557 | NA | CYP2C19 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 19 | 11076 | -0.004 | -0.2337 | No |
| 10 | 4129 | NA | MAOB Entrez, Source | monoamine oxidase B | 11412 | -0.009 | -0.2476 | No |
| 11 | 55775 | NA | TDP1 Entrez, Source | tyrosyl-DNA phosphodiesterase 1 | 13012 | -0.038 | -0.3152 | No |
| 12 | 247 | NA | ALOX15B Entrez, Source | arachidonate 15-lipoxygenase, type B | 14195 | -0.063 | -0.3603 | No |
| 13 | 1588 | NA | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 15107 | -0.086 | -0.3900 | No |
| 14 | 5594 | NA | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 15592 | -0.099 | -0.3985 | No |
| 15 | 3315 | NA | HSPB1 Entrez, Source | heat shock 27kDa protein 1 | 17953 | -0.187 | -0.4803 | Yes |
| 16 | 4128 | NA | MAOA Entrez, Source | monoamine oxidase A | 18625 | -0.225 | -0.4800 | Yes |
| 17 | 3357 | NA | HTR2B Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | 19513 | -0.294 | -0.4801 | Yes |
| 18 | 1576 | NA | CYP3A4 Entrez, Source | cytochrome P450, family 3, subfamily A, polypeptide 4 | 20305 | -0.385 | -0.4634 | Yes |
| 19 | 54578 | NA | UGT1A6 Entrez, Source | UDP glucuronosyltransferase 1 family, polypeptide A6 | 21819 | -1.162 | -0.3732 | Yes |
| 20 | 5468 | NA | PPARG Entrez, Source | peroxisome proliferator-activated receptor gamma | 21841 | -1.224 | -0.2066 | Yes |
| 21 | 760 | NA | CA2 Entrez, Source | carbonic anhydrase II | 21920 | -1.561 | 0.0036 | Yes |
