Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | GE_agg.GE_agg.cls#LTED_versus_MCF7p.GE_agg.cls#LTED_versus_MCF7p_repos |
| Phenotype | GE_agg.cls#LTED_versus_MCF7p_repos |
| Upregulated in class | MCF7p |
| GeneSet | RITONAVIR |
| Enrichment Score (ES) | -0.5071395 |
| Normalized Enrichment Score (NES) | -1.295125 |
| Nominal p-value | 0.14537445 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | 11309 | NA | SLCO2B1 Entrez, Source | solute carrier organic anion transporter family, member 2B1 | 1144 | 0.513 | 0.0482 | No |
| 2 | 10599 | NA | SLCO1B1 Entrez, Source | solute carrier organic anion transporter family, member 1B1 | 1685 | 0.409 | 0.1034 | No |
| 3 | 7421 | NA | VDR Entrez, Source | vitamin D (1,25- dihydroxyvitamin D3) receptor | 3726 | 0.201 | 0.0499 | No |
| 4 | 28234 | NA | SLCO1B3 Entrez, Source | solute carrier organic anion transporter family, member 1B3 | 3919 | 0.188 | 0.0779 | No |
| 5 | 2648 | NA | KAT2A Entrez, Source | K(lysine) acetyltransferase 2A | 4821 | 0.140 | 0.0642 | No |
| 6 | 6582 | NA | SLC22A2 Entrez, Source | solute carrier family 22 (organic cation transporter), member 2 | 5885 | 0.099 | 0.0351 | No |
| 7 | 6916 | NA | TBXAS1 Entrez, Source | thromboxane A synthase 1 (platelet) | 7506 | 0.052 | -0.0284 | No |
| 8 | 8912 | NA | CACNA1H Entrez, Source | calcium channel, voltage-dependent, T type, alpha 1H subunit | 9128 | 0.023 | -0.0976 | No |
| 9 | 1565 | NA | CYP2D6 Entrez, Source | cytochrome P450, family 2, subfamily D, polypeptide 6 | 9172 | 0.023 | -0.0951 | No |
| 10 | 1559 | NA | CYP2C9 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 9 | 9513 | 0.017 | -0.1071 | No |
| 11 | 552 | NA | AVPR1A Entrez, Source | arginine vasopressin receptor 1A | 9572 | 0.017 | -0.1065 | No |
| 12 | 1557 | NA | CYP2C19 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 19 | 11076 | -0.004 | -0.1741 | No |
| 13 | 4986 | NA | OPRK1 Entrez, Source | opioid receptor, kappa 1 | 11408 | -0.009 | -0.1873 | No |
| 14 | 387129 | NA | NPSR1 Entrez, Source | neuropeptide S receptor 1 | 12156 | -0.021 | -0.2171 | No |
| 15 | 6580 | NA | SLC22A1 Entrez, Source | solute carrier family 22 (organic cation transporter), member 1 | 12847 | -0.035 | -0.2418 | No |
| 16 | 55775 | NA | TDP1 Entrez, Source | tyrosyl-DNA phosphodiesterase 1 | 13012 | -0.038 | -0.2419 | No |
| 17 | 55244 | NA | SLC47A1 Entrez, Source | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 13381 | -0.045 | -0.2498 | No |
| 18 | 6865 | NA | TACR2 Entrez, Source | tachykinin receptor 2 | 13513 | -0.048 | -0.2463 | No |
| 19 | 146802 | NA | SLC47A2 Entrez, Source | solute carrier family 47 (multidrug and toxin extrusion), member 2 | 15291 | -0.091 | -0.3095 | No |
| 20 | 1555 | NA | CYP2B6 Entrez, Source | cytochrome P450, family 2, subfamily B, polypeptide 6 | 17309 | -0.156 | -0.3709 | No |
| 21 | 1576 | NA | CYP3A4 Entrez, Source | cytochrome P450, family 3, subfamily A, polypeptide 4 | 20305 | -0.385 | -0.4320 | Yes |
| 22 | 2908 | NA | NR3C1 Entrez, Source | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 21034 | -0.516 | -0.3645 | Yes |
| 23 | 5243 | NA | ABCB1 Entrez, Source | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 21640 | -0.868 | -0.2226 | Yes |
| 24 | 5468 | NA | PPARG Entrez, Source | peroxisome proliferator-activated receptor gamma | 21841 | -1.224 | 0.0072 | Yes |
