Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | GE_agg.GE_agg.cls#LTED_versus_MCF7p.GE_agg.cls#LTED_versus_MCF7p_repos |
| Phenotype | GE_agg.cls#LTED_versus_MCF7p_repos |
| Upregulated in class | LTED |
| GeneSet | PENTAMIDINE |
| Enrichment Score (ES) | 0.56521994 |
| Normalized Enrichment Score (NES) | 1.3307374 |
| Nominal p-value | 0.13308688 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | 3358 | NA | HTR2C Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled | 136 | 1.570 | 0.3662 | Yes |
| 2 | 150 | NA | ADRA2A Entrez, Source | adrenoceptor alpha 2A | 935 | 0.575 | 0.4662 | Yes |
| 3 | 1814 | NA | DRD3 Entrez, Source | dopamine receptor D3 | 1426 | 0.453 | 0.5513 | Yes |
| 4 | 3757 | NA | KCNH2 Entrez, Source | potassium channel, voltage gated eag related subfamily H, member 2 | 2639 | 0.291 | 0.5652 | Yes |
| 5 | 6582 | NA | SLC22A2 Entrez, Source | solute carrier family 22 (organic cation transporter), member 2 | 5885 | 0.099 | 0.4410 | No |
| 6 | 1129 | NA | CHRM2 Entrez, Source | cholinergic receptor, muscarinic 2 | 6710 | 0.073 | 0.4208 | No |
| 7 | 6581 | NA | SLC22A3 Entrez, Source | solute carrier family 22 (organic cation transporter), member 3 | 8638 | 0.031 | 0.3405 | No |
| 8 | 6285 | NA | S100B Entrez, Source | S100 calcium binding protein B | 9279 | 0.021 | 0.3164 | No |
| 9 | 1133 | NA | CHRM5 Entrez, Source | cholinergic receptor, muscarinic 5 | 10564 | 0.003 | 0.2586 | No |
| 10 | 6530 | NA | SLC6A2 Entrez, Source | solute carrier family 6 (neurotransmitter transporter), member 2 | 11224 | -0.007 | 0.2302 | No |
| 11 | 6580 | NA | SLC22A1 Entrez, Source | solute carrier family 22 (organic cation transporter), member 1 | 12847 | -0.035 | 0.1646 | No |
| 12 | 55244 | NA | SLC47A1 Entrez, Source | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 13381 | -0.045 | 0.1512 | No |
| 13 | 146802 | NA | SLC47A2 Entrez, Source | solute carrier family 47 (multidrug and toxin extrusion), member 2 | 15291 | -0.091 | 0.0858 | No |
| 14 | 6531 | NA | SLC6A3 Entrez, Source | solute carrier family 6 (neurotransmitter transporter), member 3 | 17717 | -0.176 | 0.0172 | No |
| 15 | 1132 | NA | CHRM4 Entrez, Source | cholinergic receptor, muscarinic 4 | 18528 | -0.219 | 0.0324 | No |
| 16 | 4128 | NA | MAOA Entrez, Source | monoamine oxidase A | 18625 | -0.225 | 0.0814 | No |
| 17 | 3356 | NA | HTR2A Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled | 19605 | -0.304 | 0.1089 | No |
