Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | GE_agg.GE_agg.cls#LTED_versus_MCF7p.GE_agg.cls#LTED_versus_MCF7p_repos |
| Phenotype | GE_agg.cls#LTED_versus_MCF7p_repos |
| Upregulated in class | MCF7p |
| GeneSet | INDOMETHACIN |
| Enrichment Score (ES) | -0.51671946 |
| Normalized Enrichment Score (NES) | -1.292299 |
| Nominal p-value | 0.14855877 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | 5742 | NA | PTGS1 Entrez, Source | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | 328 | 0.997 | 0.1354 | No |
| 2 | 1544 | NA | CYP1A2 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 2 | 1159 | 0.511 | 0.1745 | No |
| 3 | 10599 | NA | SLCO1B1 Entrez, Source | solute carrier organic anion transporter family, member 1B1 | 1685 | 0.409 | 0.2123 | No |
| 4 | 28234 | NA | SLCO1B3 Entrez, Source | solute carrier organic anion transporter family, member 1B3 | 3919 | 0.188 | 0.1391 | No |
| 5 | 367 | NA | AR Entrez, Source | androgen receptor | 4147 | 0.175 | 0.1551 | No |
| 6 | 3576 | NA | CXCL8 Entrez, Source | chemokine (C-X-C motif) ligand 8 | 8381 | 0.036 | -0.0321 | No |
| 7 | 1565 | NA | CYP2D6 Entrez, Source | cytochrome P450, family 2, subfamily D, polypeptide 6 | 9172 | 0.023 | -0.0646 | No |
| 8 | 1559 | NA | CYP2C9 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 9 | 9513 | 0.017 | -0.0774 | No |
| 9 | 4363 | NA | ABCC1 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 9963 | 0.011 | -0.0962 | No |
| 10 | 240 | NA | ALOX5 Entrez, Source | arachidonate 5-lipoxygenase | 10390 | 0.005 | -0.1148 | No |
| 11 | 1557 | NA | CYP2C19 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 19 | 11076 | -0.004 | -0.1453 | No |
| 12 | 5743 | NA | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 11771 | -0.015 | -0.1746 | No |
| 13 | 10170 | NA | DHRS9 Entrez, Source | dehydrogenase/reductase (SDR family) member 9 | 11807 | -0.016 | -0.1738 | No |
| 14 | 11251 | NA | PTGDR2 Entrez, Source | prostaglandin D2 receptor 2 | 13052 | -0.038 | -0.2246 | No |
| 15 | 2739 | NA | GLO1 Entrez, Source | glyoxalase I | 14698 | -0.075 | -0.2882 | No |
| 16 | 6531 | NA | SLC6A3 Entrez, Source | solute carrier family 6 (neurotransmitter transporter), member 3 | 17717 | -0.176 | -0.3990 | No |
| 17 | 1576 | NA | CYP3A4 Entrez, Source | cytochrome P450, family 3, subfamily A, polypeptide 4 | 20305 | -0.385 | -0.4587 | Yes |
| 18 | 8644 | NA | AKR1C3 Entrez, Source | aldo-keto reductase family 1, member C3 | 20516 | -0.413 | -0.4060 | Yes |
| 19 | 9536 | NA | PTGES Entrez, Source | prostaglandin E synthase | 21052 | -0.521 | -0.3519 | Yes |
| 20 | 3248 | NA | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 21086 | -0.528 | -0.2738 | Yes |
| 21 | 5243 | NA | ABCB1 Entrez, Source | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 21640 | -0.868 | -0.1682 | Yes |
| 22 | 5468 | NA | PPARG Entrez, Source | peroxisome proliferator-activated receptor gamma | 21841 | -1.224 | 0.0072 | Yes |
