Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | GE_agg.GE_agg.cls#LTED_versus_MCF7p.GE_agg.cls#LTED_versus_MCF7p_repos |
| Phenotype | GE_agg.cls#LTED_versus_MCF7p_repos |
| Upregulated in class | LTED |
| GeneSet | HALOPERIDOL |
| Enrichment Score (ES) | 0.5012439 |
| Normalized Enrichment Score (NES) | 1.3570721 |
| Nominal p-value | 0.0873606 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | 3358 | NA | HTR2C Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled | 136 | 1.570 | 0.1500 | Yes |
| 2 | 1816 | NA | DRD5 Entrez, Source | dopamine receptor D5 | 583 | 0.750 | 0.2043 | Yes |
| 3 | 3363 | NA | HTR7 Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled | 748 | 0.652 | 0.2618 | Yes |
| 4 | 1815 | NA | DRD4 Entrez, Source | dopamine receptor D4 | 912 | 0.580 | 0.3120 | Yes |
| 5 | 150 | NA | ADRA2A Entrez, Source | adrenoceptor alpha 2A | 935 | 0.575 | 0.3682 | Yes |
| 6 | 1128 | NA | CHRM1 Entrez, Source | cholinergic receptor, muscarinic 1 | 1231 | 0.495 | 0.4041 | Yes |
| 7 | 1814 | NA | DRD3 Entrez, Source | dopamine receptor D3 | 1426 | 0.453 | 0.4403 | Yes |
| 8 | 146 | NA | ADRA1D Entrez, Source | adrenoceptor alpha 1D | 1431 | 0.451 | 0.4850 | Yes |
| 9 | 3350 | NA | HTR1A Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled | 2194 | 0.344 | 0.4845 | Yes |
| 10 | 3757 | NA | KCNH2 Entrez, Source | potassium channel, voltage gated eag related subfamily H, member 2 | 2639 | 0.291 | 0.4933 | Yes |
| 11 | 1812 | NA | DRD1 Entrez, Source | dopamine receptor D1 | 3023 | 0.255 | 0.5012 | Yes |
| 12 | 367 | NA | AR Entrez, Source | androgen receptor | 4147 | 0.175 | 0.4675 | No |
| 13 | 3269 | NA | HRH1 Entrez, Source | histamine receptor H1 | 4437 | 0.158 | 0.4701 | No |
| 14 | 51053 | NA | GMNN Entrez, Source | geminin, DNA replication inhibitor | 5703 | 0.105 | 0.4230 | No |
| 15 | 6532 | NA | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter), member 4 | 6572 | 0.077 | 0.3911 | No |
| 16 | 152 | NA | ADRA2C Entrez, Source | adrenoceptor alpha 2C | 6764 | 0.071 | 0.3895 | No |
| 17 | 3352 | NA | HTR1D Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled | 7023 | 0.064 | 0.3841 | No |
| 18 | 3553 | NA | IL1B Entrez, Source | interleukin 1, beta | 7060 | 0.062 | 0.3887 | No |
| 19 | 1565 | NA | CYP2D6 Entrez, Source | cytochrome P450, family 2, subfamily D, polypeptide 6 | 9172 | 0.023 | 0.2949 | No |
| 20 | 1813 | NA | DRD2 Entrez, Source | dopamine receptor D2 | 9209 | 0.022 | 0.2954 | No |
| 21 | 1133 | NA | CHRM5 Entrez, Source | cholinergic receptor, muscarinic 5 | 10564 | 0.003 | 0.2341 | No |
| 22 | 6530 | NA | SLC6A2 Entrez, Source | solute carrier family 6 (neurotransmitter transporter), member 2 | 11224 | -0.007 | 0.2047 | No |
| 23 | 4988 | NA | OPRM1 Entrez, Source | opioid receptor, mu 1 | 11537 | -0.011 | 0.1916 | No |
| 24 | 8856 | NA | NR1I2 Entrez, Source | nuclear receptor subfamily 1, group I, member 2 | 12246 | -0.023 | 0.1617 | No |
| 25 | 55775 | NA | TDP1 Entrez, Source | tyrosyl-DNA phosphodiesterase 1 | 13012 | -0.038 | 0.1306 | No |
| 26 | 10682 | NA | EBP Entrez, Source | emopamil binding protein (sterol isomerase) | 14438 | -0.069 | 0.0726 | No |
| 27 | 10280 | NA | SIGMAR1 Entrez, Source | sigma non-opioid intracellular receptor 1 | 14929 | -0.081 | 0.0583 | No |
| 28 | 2475 | NA | MTOR Entrez, Source | mechanistic target of rapamycin (serine/threonine kinase) | 16530 | -0.128 | -0.0018 | No |
| 29 | 3274 | NA | HRH2 Entrez, Source | histamine receptor H2 | 17234 | -0.153 | -0.0186 | No |
| 30 | 1132 | NA | CHRM4 Entrez, Source | cholinergic receptor, muscarinic 4 | 18528 | -0.219 | -0.0557 | No |
| 31 | 151 | NA | ADRA2B Entrez, Source | adrenoceptor alpha 2B | 18865 | -0.241 | -0.0470 | No |
| 32 | 3357 | NA | HTR2B Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | 19513 | -0.294 | -0.0472 | No |
| 33 | 3356 | NA | HTR2A Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled | 19605 | -0.304 | -0.0211 | No |
| 34 | 1576 | NA | CYP3A4 Entrez, Source | cytochrome P450, family 3, subfamily A, polypeptide 4 | 20305 | -0.385 | -0.0147 | No |
| 35 | 3362 | NA | HTR6 Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled | 21682 | -0.922 | 0.0144 | No |
