Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | GE_agg.GE_agg.cls#LTED_versus_MCF7p.GE_agg.cls#LTED_versus_MCF7p_repos |
| Phenotype | GE_agg.cls#LTED_versus_MCF7p_repos |
| Upregulated in class | MCF7p |
| GeneSet | FLOXURIDINE |
| Enrichment Score (ES) | -0.476993 |
| Normalized Enrichment Score (NES) | -1.1625366 |
| Nominal p-value | 0.24844721 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | 1544 | NA | CYP1A2 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 2 | 1159 | 0.511 | 0.0872 | No |
| 2 | 4780 | NA | NFE2L2 Entrez, Source | nuclear factor, erythroid 2-like 2 | 3546 | 0.213 | 0.0370 | No |
| 3 | 351 | NA | APP Entrez, Source | amyloid beta (A4) precursor protein | 5146 | 0.125 | -0.0014 | No |
| 4 | 7157 | NA | TP53 Entrez, Source | tumor protein p53 | 5673 | 0.106 | 0.0037 | No |
| 5 | 5970 | NA | RELA Entrez, Source | v-rel avian reticuloendotheliosis viral oncogene homolog A | 6238 | 0.088 | 0.0020 | No |
| 6 | 1565 | NA | CYP2D6 Entrez, Source | cytochrome P450, family 2, subfamily D, polypeptide 6 | 9172 | 0.023 | -0.1252 | No |
| 7 | 1559 | NA | CYP2C9 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 9 | 9513 | 0.017 | -0.1358 | No |
| 8 | 7298 | NA | TYMS Entrez, Source | thymidylate synthetase | 10643 | 0.002 | -0.1867 | No |
| 9 | 1557 | NA | CYP2C19 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 19 | 11076 | -0.004 | -0.2052 | No |
| 10 | 55775 | NA | TDP1 Entrez, Source | tyrosyl-DNA phosphodiesterase 1 | 13012 | -0.038 | -0.2829 | No |
| 11 | 4790 | NA | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 15214 | -0.088 | -0.3588 | No |
| 12 | 8202 | NA | NCOA3 Entrez, Source | nuclear receptor coactivator 3 | 15366 | -0.093 | -0.3403 | No |
| 13 | 4323 | NA | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 18372 | -0.210 | -0.4194 | Yes |
| 14 | 8648 | NA | NCOA1 Entrez, Source | nuclear receptor coactivator 1 | 18771 | -0.234 | -0.3732 | Yes |
| 15 | 3717 | NA | JAK2 Entrez, Source | Janus kinase 2 | 19722 | -0.317 | -0.3296 | Yes |
| 16 | 3417 | NA | IDH1 Entrez, Source | isocitrate dehydrogenase 1 (NADP+), soluble | 19917 | -0.337 | -0.2462 | Yes |
| 17 | 1576 | NA | CYP3A4 Entrez, Source | cytochrome P450, family 3, subfamily A, polypeptide 4 | 20305 | -0.385 | -0.1583 | Yes |
| 18 | 688 | NA | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 21629 | -0.859 | 0.0168 | Yes |
