Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | GE_agg.GE_agg.cls#LTED_versus_MCF7p.GE_agg.cls#LTED_versus_MCF7p_repos |
| Phenotype | GE_agg.cls#LTED_versus_MCF7p_repos |
| Upregulated in class | LTED |
| GeneSet | DOXORUBICIN |
| Enrichment Score (ES) | 0.54354155 |
| Normalized Enrichment Score (NES) | 1.3008252 |
| Nominal p-value | 0.17073171 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | 3932 | NA | LCK Entrez, Source | LCK proto-oncogene, Src family tyrosine kinase | 803 | 0.624 | 0.1182 | Yes |
| 2 | 8714 | NA | ABCC3 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 885 | 0.594 | 0.2617 | Yes |
| 3 | 1544 | NA | CYP1A2 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 2 | 1159 | 0.511 | 0.3759 | Yes |
| 4 | 1128 | NA | CHRM1 Entrez, Source | cholinergic receptor, muscarinic 1 | 1231 | 0.495 | 0.4955 | Yes |
| 5 | 2064 | NA | ERBB2 Entrez, Source | erb-b2 receptor tyrosine kinase 2 | 3345 | 0.228 | 0.4557 | Yes |
| 6 | 598 | NA | BCL2L1 Entrez, Source | BCL2-like 1 | 3798 | 0.196 | 0.4837 | Yes |
| 7 | 28234 | NA | SLCO1B3 Entrez, Source | solute carrier organic anion transporter family, member 1B3 | 3919 | 0.188 | 0.5250 | Yes |
| 8 | 65975 | NA | STK33 Entrez, Source | serine/threonine kinase 33 | 4391 | 0.161 | 0.5435 | Yes |
| 9 | 596 | NA | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 6678 | 0.074 | 0.4578 | No |
| 10 | 2534 | NA | FYN Entrez, Source | FYN proto-oncogene, Src family tyrosine kinase | 7000 | 0.064 | 0.4592 | No |
| 11 | 7155 | NA | TOP2B Entrez, Source | topoisomerase (DNA) II beta 180kDa | 8570 | 0.032 | 0.3958 | No |
| 12 | 1565 | NA | CYP2D6 Entrez, Source | cytochrome P450, family 2, subfamily D, polypeptide 6 | 9172 | 0.023 | 0.3741 | No |
| 13 | 1559 | NA | CYP2C9 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 9 | 9513 | 0.017 | 0.3629 | No |
| 14 | 1557 | NA | CYP2C19 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 19 | 11076 | -0.004 | 0.2929 | No |
| 15 | 1717 | NA | DHCR7 Entrez, Source | 7-dehydrocholesterol reductase | 13569 | -0.049 | 0.1918 | No |
| 16 | 10682 | NA | EBP Entrez, Source | emopamil binding protein (sterol isomerase) | 14438 | -0.069 | 0.1694 | No |
| 17 | 7153 | NA | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 14921 | -0.081 | 0.1675 | No |
| 18 | 7150 | NA | TOP1 Entrez, Source | topoisomerase (DNA) I | 14942 | -0.081 | 0.1867 | No |
| 19 | 51426 | NA | POLK Entrez, Source | polymerase (DNA directed) kappa | 16152 | -0.116 | 0.1604 | No |
| 20 | 834 | NA | CASP1 Entrez, Source | caspase 1, apoptosis-related cysteine peptidase | 20576 | -0.426 | 0.0647 | No |
