Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | GE_agg.GE_agg.cls#LTED_versus_MCF7p.GE_agg.cls#LTED_versus_MCF7p_repos |
| Phenotype | GE_agg.cls#LTED_versus_MCF7p_repos |
| Upregulated in class | LTED |
| GeneSet | DIPHENHYDRAMINE |
| Enrichment Score (ES) | 0.54342186 |
| Normalized Enrichment Score (NES) | 1.2861117 |
| Nominal p-value | 0.16572505 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | 3358 | NA | HTR2C Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled | 136 | 1.570 | 0.3075 | Yes |
| 2 | 1544 | NA | CYP1A2 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 2 | 1159 | 0.511 | 0.3630 | Yes |
| 3 | 1128 | NA | CHRM1 Entrez, Source | cholinergic receptor, muscarinic 1 | 1231 | 0.495 | 0.4588 | Yes |
| 4 | 1814 | NA | DRD3 Entrez, Source | dopamine receptor D3 | 1426 | 0.453 | 0.5404 | Yes |
| 5 | 3757 | NA | KCNH2 Entrez, Source | potassium channel, voltage gated eag related subfamily H, member 2 | 2639 | 0.291 | 0.5434 | Yes |
| 6 | 1131 | NA | CHRM3 Entrez, Source | cholinergic receptor, muscarinic 3 | 4416 | 0.159 | 0.4945 | No |
| 7 | 3269 | NA | HRH1 Entrez, Source | histamine receptor H1 | 4437 | 0.158 | 0.5251 | No |
| 8 | 1129 | NA | CHRM2 Entrez, Source | cholinergic receptor, muscarinic 2 | 6710 | 0.073 | 0.4364 | No |
| 9 | 59340 | NA | HRH4 Entrez, Source | histamine receptor H4 | 8189 | 0.039 | 0.3770 | No |
| 10 | 1565 | NA | CYP2D6 Entrez, Source | cytochrome P450, family 2, subfamily D, polypeptide 6 | 9172 | 0.023 | 0.3369 | No |
| 11 | 1559 | NA | CYP2C9 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 9 | 9513 | 0.017 | 0.3249 | No |
| 12 | 1133 | NA | CHRM5 Entrez, Source | cholinergic receptor, muscarinic 5 | 10564 | 0.003 | 0.2777 | No |
| 13 | 1557 | NA | CYP2C19 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 19 | 11076 | -0.004 | 0.2553 | No |
| 14 | 6530 | NA | SLC6A2 Entrez, Source | solute carrier family 6 (neurotransmitter transporter), member 2 | 11224 | -0.007 | 0.2499 | No |
| 15 | 1132 | NA | CHRM4 Entrez, Source | cholinergic receptor, muscarinic 4 | 18528 | -0.219 | -0.0385 | No |
| 16 | 3357 | NA | HTR2B Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | 19513 | -0.294 | -0.0246 | No |
| 17 | 3356 | NA | HTR2A Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled | 19605 | -0.304 | 0.0319 | No |
| 18 | 1576 | NA | CYP3A4 Entrez, Source | cytochrome P450, family 3, subfamily A, polypeptide 4 | 20305 | -0.385 | 0.0771 | No |
