Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | GE_agg.GE_agg.cls#LTED_versus_MCF7p.GE_agg.cls#LTED_versus_MCF7p_repos |
| Phenotype | GE_agg.cls#LTED_versus_MCF7p_repos |
| Upregulated in class | LTED |
| GeneSet | DEXCHLORPHENIRAMINE |
| Enrichment Score (ES) | 0.5522394 |
| Normalized Enrichment Score (NES) | 1.2909971 |
| Nominal p-value | 0.16078432 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | 3358 | NA | HTR2C Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled | 136 | 1.570 | 0.3058 | Yes |
| 2 | 150 | NA | ADRA2A Entrez, Source | adrenoceptor alpha 2A | 935 | 0.575 | 0.3837 | Yes |
| 3 | 1128 | NA | CHRM1 Entrez, Source | cholinergic receptor, muscarinic 1 | 1231 | 0.495 | 0.4687 | Yes |
| 4 | 146 | NA | ADRA1D Entrez, Source | adrenoceptor alpha 1D | 1431 | 0.451 | 0.5493 | Yes |
| 5 | 3757 | NA | KCNH2 Entrez, Source | potassium channel, voltage gated eag related subfamily H, member 2 | 2639 | 0.291 | 0.5522 | Yes |
| 6 | 1131 | NA | CHRM3 Entrez, Source | cholinergic receptor, muscarinic 3 | 4416 | 0.159 | 0.5031 | No |
| 7 | 3269 | NA | HRH1 Entrez, Source | histamine receptor H1 | 4437 | 0.158 | 0.5336 | No |
| 8 | 6532 | NA | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter), member 4 | 6572 | 0.077 | 0.4519 | No |
| 9 | 1129 | NA | CHRM2 Entrez, Source | cholinergic receptor, muscarinic 2 | 6710 | 0.073 | 0.4601 | No |
| 10 | 1133 | NA | CHRM5 Entrez, Source | cholinergic receptor, muscarinic 5 | 10564 | 0.003 | 0.2854 | No |
| 11 | 6530 | NA | SLC6A2 Entrez, Source | solute carrier family 6 (neurotransmitter transporter), member 2 | 11224 | -0.007 | 0.2567 | No |
| 12 | 10280 | NA | SIGMAR1 Entrez, Source | sigma non-opioid intracellular receptor 1 | 14929 | -0.081 | 0.1043 | No |
| 13 | 3274 | NA | HRH2 Entrez, Source | histamine receptor H2 | 17234 | -0.153 | 0.0298 | No |
| 14 | 6531 | NA | SLC6A3 Entrez, Source | solute carrier family 6 (neurotransmitter transporter), member 3 | 17717 | -0.176 | 0.0428 | No |
| 15 | 1132 | NA | CHRM4 Entrez, Source | cholinergic receptor, muscarinic 4 | 18528 | -0.219 | 0.0496 | No |
| 16 | 151 | NA | ADRA2B Entrez, Source | adrenoceptor alpha 2B | 18865 | -0.241 | 0.0822 | No |
| 17 | 3356 | NA | HTR2A Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled | 19605 | -0.304 | 0.1089 | No |
