Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | GE_agg.GE_agg.cls#LTED_versus_MCF7p.GE_agg.cls#LTED_versus_MCF7p_repos |
| Phenotype | GE_agg.cls#LTED_versus_MCF7p_repos |
| Upregulated in class | LTED |
| GeneSet | AMIODARONE |
| Enrichment Score (ES) | 0.46167412 |
| Normalized Enrichment Score (NES) | 1.3064744 |
| Nominal p-value | 0.09490334 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | 3358 | NA | HTR2C Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled | 136 | 1.570 | 0.1242 | Yes |
| 2 | 729230 | NA | CCR2 Entrez, Source | chemokine (C-C motif) receptor 2 | 588 | 0.746 | 0.1656 | Yes |
| 3 | 153 | NA | ADRB1 Entrez, Source | adrenoceptor beta 1 | 611 | 0.730 | 0.2253 | Yes |
| 4 | 1815 | NA | DRD4 Entrez, Source | dopamine receptor D4 | 912 | 0.580 | 0.2597 | Yes |
| 5 | 150 | NA | ADRA2A Entrez, Source | adrenoceptor alpha 2A | 935 | 0.575 | 0.3065 | Yes |
| 6 | 1544 | NA | CYP1A2 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 2 | 1159 | 0.511 | 0.3387 | Yes |
| 7 | 1128 | NA | CHRM1 Entrez, Source | cholinergic receptor, muscarinic 1 | 1231 | 0.495 | 0.3766 | Yes |
| 8 | 1814 | NA | DRD3 Entrez, Source | dopamine receptor D3 | 1426 | 0.453 | 0.4054 | Yes |
| 9 | 1233 | NA | CCR4 Entrez, Source | chemokine (C-C motif) receptor 4 | 1765 | 0.397 | 0.4229 | Yes |
| 10 | 140 | NA | ADORA3 Entrez, Source | adenosine A3 receptor | 2484 | 0.309 | 0.4159 | Yes |
| 11 | 3757 | NA | KCNH2 Entrez, Source | potassium channel, voltage gated eag related subfamily H, member 2 | 2639 | 0.291 | 0.4330 | Yes |
| 12 | 1812 | NA | DRD1 Entrez, Source | dopamine receptor D1 | 3023 | 0.255 | 0.4368 | Yes |
| 13 | 4985 | NA | OPRD1 Entrez, Source | opioid receptor, delta 1 | 3107 | 0.248 | 0.4536 | Yes |
| 14 | 2064 | NA | ERBB2 Entrez, Source | erb-b2 receptor tyrosine kinase 2 | 3345 | 0.228 | 0.4617 | Yes |
| 15 | 1131 | NA | CHRM3 Entrez, Source | cholinergic receptor, muscarinic 3 | 4416 | 0.159 | 0.4262 | No |
| 16 | 4160 | NA | MC4R Entrez, Source | melanocortin 4 receptor | 5133 | 0.126 | 0.4040 | No |
| 17 | 51053 | NA | GMNN Entrez, Source | geminin, DNA replication inhibitor | 5703 | 0.105 | 0.3868 | No |
| 18 | 6713 | NA | SQLE Entrez, Source | squalene epoxidase | 6110 | 0.091 | 0.3759 | No |
| 19 | 6532 | NA | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter), member 4 | 6572 | 0.077 | 0.3613 | No |
| 20 | 1129 | NA | CHRM2 Entrez, Source | cholinergic receptor, muscarinic 2 | 6710 | 0.073 | 0.3611 | No |
| 21 | 2534 | NA | FYN Entrez, Source | FYN proto-oncogene, Src family tyrosine kinase | 7000 | 0.064 | 0.3533 | No |
| 22 | 10951 | NA | CBX1 Entrez, Source | chromobox homolog 1 | 7130 | 0.061 | 0.3525 | No |
| 23 | 1565 | NA | CYP2D6 Entrez, Source | cytochrome P450, family 2, subfamily D, polypeptide 6 | 9172 | 0.023 | 0.2614 | No |
| 24 | 1813 | NA | DRD2 Entrez, Source | dopamine receptor D2 | 9209 | 0.022 | 0.2616 | No |
| 25 | 1559 | NA | CYP2C9 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 9 | 9513 | 0.017 | 0.2492 | No |
| 26 | 1133 | NA | CHRM5 Entrez, Source | cholinergic receptor, muscarinic 5 | 10564 | 0.003 | 0.2016 | No |
| 27 | 1557 | NA | CYP2C19 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 19 | 11076 | -0.004 | 0.1787 | No |
| 28 | 6530 | NA | SLC6A2 Entrez, Source | solute carrier family 6 (neurotransmitter transporter), member 2 | 11224 | -0.007 | 0.1726 | No |
| 29 | 4161 | NA | MC5R Entrez, Source | melanocortin 5 receptor | 11236 | -0.007 | 0.1727 | No |
| 30 | 4986 | NA | OPRK1 Entrez, Source | opioid receptor, kappa 1 | 11408 | -0.009 | 0.1656 | No |
| 31 | 4988 | NA | OPRM1 Entrez, Source | opioid receptor, mu 1 | 11537 | -0.011 | 0.1607 | No |
| 32 | 6865 | NA | TACR2 Entrez, Source | tachykinin receptor 2 | 13513 | -0.048 | 0.0748 | No |
| 33 | 10682 | NA | EBP Entrez, Source | emopamil binding protein (sterol isomerase) | 14438 | -0.069 | 0.0384 | No |
| 34 | 10280 | NA | SIGMAR1 Entrez, Source | sigma non-opioid intracellular receptor 1 | 14929 | -0.081 | 0.0228 | No |
| 35 | 4159 | NA | MC3R Entrez, Source | melanocortin 3 receptor | 15860 | -0.107 | -0.0107 | No |
| 36 | 624 | NA | BDKRB2 Entrez, Source | bradykinin receptor B2 | 16345 | -0.122 | -0.0226 | No |
| 37 | 2475 | NA | MTOR Entrez, Source | mechanistic target of rapamycin (serine/threonine kinase) | 16530 | -0.128 | -0.0204 | No |
| 38 | 3274 | NA | HRH2 Entrez, Source | histamine receptor H2 | 17234 | -0.153 | -0.0397 | No |
| 39 | 6531 | NA | SLC6A3 Entrez, Source | solute carrier family 6 (neurotransmitter transporter), member 3 | 17717 | -0.176 | -0.0471 | No |
| 40 | 1132 | NA | CHRM4 Entrez, Source | cholinergic receptor, muscarinic 4 | 18528 | -0.219 | -0.0658 | No |
| 41 | 151 | NA | ADRA2B Entrez, Source | adrenoceptor alpha 2B | 18865 | -0.241 | -0.0610 | No |
| 42 | 3357 | NA | HTR2B Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | 19513 | -0.294 | -0.0661 | No |
| 43 | 3356 | NA | HTR2A Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled | 19605 | -0.304 | -0.0451 | No |
| 44 | 155 | NA | ADRB3 Entrez, Source | adrenoceptor beta 3 | 20346 | -0.391 | -0.0463 | No |
| 45 | 1909 | NA | EDNRA Entrez, Source | endothelin receptor type A | 21132 | -0.541 | -0.0371 | No |
| 46 | 3362 | NA | HTR6 Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled | 21682 | -0.922 | 0.0144 | No |
