Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | GE_agg.GE_agg.cls#LTED_versus_MCF7n.GE_agg.cls#LTED_versus_MCF7n_repos |
| Phenotype | GE_agg.cls#LTED_versus_MCF7n_repos |
| Upregulated in class | MCF7n |
| GeneSet | GTGTTGA,MIR-505 |
| Enrichment Score (ES) | -0.41766107 |
| Normalized Enrichment Score (NES) | -1.372458 |
| Nominal p-value | 0.025540275 |
| FDR q-value | 0.84586567 |
| FWER p-Value | 0.966 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | 817 | NA | CAMK2D Entrez, Source | calcium/calmodulin-dependent protein kinase II delta | 1057 | 0.472 | -0.0259 | No |
| 2 | 56901 | NA | NDUFA4L2 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 1063 | 0.471 | -0.0038 | No |
| 3 | 23143 | NA | LRCH1 Entrez, Source | leucine-rich repeats and calponin homology (CH) domain containing 1 | 1510 | 0.387 | -0.0058 | No |
| 4 | 54329 | NA | GPR85 Entrez, Source | G protein-coupled receptor 85 | 1537 | 0.382 | 0.0111 | No |
| 5 | 26999 | NA | CYFIP2 Entrez, Source | cytoplasmic FMR1 interacting protein 2 | 1682 | 0.363 | 0.0217 | No |
| 6 | 10858 | NA | CYP46A1 Entrez, Source | cytochrome P450, family 46, subfamily A, polypeptide 1 | 1828 | 0.342 | 0.0313 | No |
| 7 | 4601 | NA | MXI1 Entrez, Source | MAX interactor 1, dimerization protein | 2314 | 0.285 | 0.0227 | No |
| 8 | 10370 | NA | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 2429 | 0.274 | 0.0305 | No |
| 9 | 374864 | NA | CCDC178 Entrez, Source | coiled-coil domain containing 178 | 2587 | 0.258 | 0.0355 | No |
| 10 | 11217 | NA | AKAP2 Entrez, Source | A kinase (PRKA) anchor protein 2 | 2747 | 0.244 | 0.0399 | No |
| 11 | 4303 | NA | FOXO4 Entrez, Source | forkhead box O4 | 2932 | 0.228 | 0.0423 | No |
| 12 | 253943 | NA | YTHDF3 Entrez, Source | YTH N(6)-methyladenosine RNA binding protein 3 | 3061 | 0.218 | 0.0467 | No |
| 13 | 23410 | NA | SIRT3 Entrez, Source | sirtuin 3 | 3086 | 0.217 | 0.0559 | No |
| 14 | 8653 | NA | DDX3Y Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 3297 | 0.201 | 0.0559 | No |
| 15 | 94032 | NA | CAMK2N2 Entrez, Source | calcium/calmodulin-dependent protein kinase II inhibitor 2 | 3626 | 0.180 | 0.0494 | No |
| 16 | 9729 | NA | KIAA0408 Entrez, Source | KIAA0408 | 3774 | 0.171 | 0.0508 | No |
| 17 | 10075 | NA | HUWE1 Entrez, Source | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 3786 | 0.171 | 0.0584 | No |
| 18 | 51646 | NA | YPEL5 Entrez, Source | yippee-like 5 (Drosophila) | 3929 | 0.163 | 0.0597 | No |
| 19 | 23060 | NA | ZNF609 Entrez, Source | zinc finger protein 609 | 4324 | 0.144 | 0.0485 | No |
| 20 | 5144 | NA | PDE4D Entrez, Source | phosphodiesterase 4D, cAMP-specific | 4455 | 0.137 | 0.0491 | No |
| 21 | 55593 | NA | OTUD5 Entrez, Source | OTU deubiquitinase 5 | 4523 | 0.134 | 0.0524 | No |
| 22 | 5170 | NA | PDPK1 Entrez, Source | 3-phosphoinositide dependent protein kinase 1 | 5020 | 0.114 | 0.0351 | No |
| 23 | 55031 | NA | USP47 Entrez, Source | ubiquitin specific peptidase 47 | 5272 | 0.106 | 0.0287 | No |
| 24 | 1432 | NA | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 5432 | 0.101 | 0.0262 | No |
| 25 | 80817 | NA | CEP44 Entrez, Source | centrosomal protein 44kDa | 5771 | 0.090 | 0.0151 | No |
| 26 | 8165 | NA | AKAP1 Entrez, Source | A kinase (PRKA) anchor protein 1 | 5842 | 0.088 | 0.0160 | No |
| 27 | 54726 | NA | OTUD4 Entrez, Source | OTU deubiquitinase 4 | 6544 | 0.069 | -0.0127 | No |
| 28 | 406 | NA | ARNTL Entrez, Source | aryl hydrocarbon receptor nuclear translocator-like | 6735 | 0.064 | -0.0184 | No |
| 29 | 6571 | NA | SLC18A2 Entrez, Source | solute carrier family 18 (vesicular monoamine transporter), member 2 | 6798 | 0.062 | -0.0182 | No |
| 30 | 10771 | NA | ZMYND11 Entrez, Source | zinc finger, MYND-type containing 11 | 7364 | 0.050 | -0.0417 | No |
| 31 | 64207 | NA | IRF2BPL Entrez, Source | interferon regulatory factor 2 binding protein-like | 7483 | 0.047 | -0.0448 | No |
| 32 | 23299 | NA | BICD2 Entrez, Source | bicaudal D homolog 2 (Drosophila) | 7590 | 0.045 | -0.0476 | No |
| 33 | 4779 | NA | NFE2L1 Entrez, Source | nuclear factor, erythroid 2-like 1 | 7768 | 0.041 | -0.0537 | No |
| 34 | 491 | NA | ATP2B2 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 2 | 7898 | 0.038 | -0.0578 | No |
| 35 | 10658 | NA | CELF1 Entrez, Source | CUGBP, Elav-like family member 1 | 8107 | 0.034 | -0.0656 | No |
| 36 | 90488 | NA | TMEM263 Entrez, Source | transmembrane protein 263 | 8817 | 0.021 | -0.0970 | No |
| 37 | 1993 | NA | ELAVL2 Entrez, Source | ELAV like neuron-specific RNA binding protein 2 | 9247 | 0.014 | -0.1159 | No |
| 38 | 154743 | NA | C7ORF60 Entrez, Source | chromosome 7 open reading frame 60 | 9529 | 0.010 | -0.1283 | No |
| 39 | 8661 | NA | EIF3A Entrez, Source | eukaryotic translation initiation factor 3, subunit A | 10118 | 0.004 | -0.1550 | No |
| 40 | 10472 | NA | ZBTB18 Entrez, Source | zinc finger and BTB domain containing 18 | 10710 | -0.003 | -0.1818 | No |
| 41 | 23380 | NA | SRGAP2 Entrez, Source | SLIT-ROBO Rho GTPase activating protein 2 | 10903 | -0.005 | -0.1904 | No |
| 42 | 4204 | NA | MECP2 Entrez, Source | methyl CpG binding protein 2 | 11481 | -0.010 | -0.2162 | No |
| 43 | 6426 | NA | SRSF1 Entrez, Source | serine/arginine-rich splicing factor 1 | 11657 | -0.012 | -0.2237 | No |
| 44 | 1665 | NA | DHX15 Entrez, Source | DEAH (Asp-Glu-Ala-His) box helicase 15 | 11801 | -0.014 | -0.2295 | No |
| 45 | 2740 | NA | GLP1R Entrez, Source | glucagon-like peptide 1 receptor | 11944 | -0.015 | -0.2353 | No |
| 46 | 10175 | NA | CNIH1 Entrez, Source | cornichon family AMPA receptor auxiliary protein 1 | 11979 | -0.016 | -0.2361 | No |
| 47 | 6651 | NA | SON Entrez, Source | SON DNA binding protein | 12707 | -0.026 | -0.2681 | No |
| 48 | 10657 | NA | KHDRBS1 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 1 | 12729 | -0.026 | -0.2678 | No |
| 49 | 130507 | NA | UBR3 Entrez, Source | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 13274 | -0.035 | -0.2910 | No |
| 50 | 5250 | NA | SLC25A3 Entrez, Source | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 13290 | -0.035 | -0.2901 | No |
| 51 | 55591 | NA | VEZT Entrez, Source | vezatin, adherens junctions transmembrane protein | 13432 | -0.038 | -0.2947 | No |
| 52 | 55167 | NA | MSL2 Entrez, Source | male-specific lethal 2 homolog (Drosophila) | 13607 | -0.041 | -0.3007 | No |
| 53 | 22838 | NA | RNF44 Entrez, Source | ring finger protein 44 | 13869 | -0.045 | -0.3105 | No |
| 54 | 65056 | NA | GPBP1 Entrez, Source | GC-rich promoter binding protein 1 | 13870 | -0.045 | -0.3084 | No |
| 55 | 8545 | NA | CGGBP1 Entrez, Source | CGG triplet repeat binding protein 1 | 13885 | -0.045 | -0.3069 | No |
| 56 | 79718 | NA | TBL1XR1 Entrez, Source | transducin (beta)-like 1 X-linked receptor 1 | 13993 | -0.047 | -0.3095 | No |
| 57 | 79727 | NA | LIN28A Entrez, Source | lin-28 homolog A (C. elegans) | 14276 | -0.052 | -0.3199 | No |
| 58 | 57679 | NA | ALS2 Entrez, Source | amyotrophic lateral sclerosis 2 (juvenile) | 14314 | -0.053 | -0.3191 | No |
| 59 | 23608 | NA | MKRN1 Entrez, Source | makorin ring finger protein 1 | 14326 | -0.053 | -0.3171 | No |
| 60 | 1385 | NA | CREB1 Entrez, Source | cAMP responsive element binding protein 1 | 14555 | -0.058 | -0.3247 | No |
| 61 | 4154 | NA | MBNL1 Entrez, Source | muscleblind-like splicing regulator 1 | 14778 | -0.063 | -0.3318 | No |
| 62 | 1654 | NA | DDX3X Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 14812 | -0.064 | -0.3303 | No |
| 63 | 23466 | NA | CBX6 Entrez, Source | chromobox homolog 6 | 14983 | -0.067 | -0.3349 | No |
| 64 | 116224 | NA | FAM122A Entrez, Source | family with sequence similarity 122A | 15207 | -0.072 | -0.3417 | No |
| 65 | 821 | NA | CANX Entrez, Source | calnexin | 15329 | -0.075 | -0.3437 | No |
| 66 | 85465 | NA | EPT1 Entrez, Source | ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific) | 15675 | -0.083 | -0.3555 | No |
| 67 | 7323 | NA | UBE2D3 Entrez, Source | ubiquitin-conjugating enzyme E2D 3 | 15779 | -0.086 | -0.3561 | No |
| 68 | 50863 | NA | NTM Entrez, Source | neurotrimin | 15794 | -0.086 | -0.3527 | No |
| 69 | 22905 | NA | EPN2 Entrez, Source | epsin 2 | 16115 | -0.096 | -0.3628 | No |
| 70 | 204851 | NA | HIPK1 Entrez, Source | homeodomain interacting protein kinase 1 | 16410 | -0.105 | -0.3712 | No |
| 71 | 490 | NA | ATP2B1 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 1 | 16580 | -0.110 | -0.3738 | No |
| 72 | 3268 | NA | AGFG2 Entrez, Source | ArfGAP with FG repeats 2 | 16716 | -0.114 | -0.3745 | No |
| 73 | 3845 | NA | KRAS Entrez, Source | Kirsten rat sarcoma viral oncogene homolog | 17051 | -0.126 | -0.3838 | No |
| 74 | 1809 | NA | DPYSL3 Entrez, Source | dihydropyrimidinase-like 3 | 17361 | -0.138 | -0.3914 | No |
| 75 | 5376 | NA | PMP22 Entrez, Source | peripheral myelin protein 22 | 17442 | -0.141 | -0.3884 | No |
| 76 | 84669 | NA | USP32 Entrez, Source | ubiquitin specific peptidase 32 | 17588 | -0.146 | -0.3880 | No |
| 77 | 146057 | NA | TTBK2 Entrez, Source | tau tubulin kinase 2 | 17640 | -0.149 | -0.3833 | No |
| 78 | 23168 | NA | RTF1 Entrez, Source | Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 17815 | -0.156 | -0.3839 | No |
| 79 | 79154 | NA | DHRS11 Entrez, Source | dehydrogenase/reductase (SDR family) member 11 | 17854 | -0.158 | -0.3781 | No |
| 80 | 10048 | NA | RANBP9 Entrez, Source | RAN binding protein 9 | 17870 | -0.159 | -0.3712 | No |
| 81 | 57630 | NA | SH3RF1 Entrez, Source | SH3 domain containing ring finger 1 | 17949 | -0.163 | -0.3671 | No |
| 82 | 3759 | NA | KCNJ2 Entrez, Source | potassium channel, inwardly rectifying subfamily J, member 2 | 18021 | -0.165 | -0.3625 | No |
| 83 | 9098 | NA | USP6 Entrez, Source | ubiquitin specific peptidase 6 | 18154 | -0.172 | -0.3604 | No |
| 84 | 94239 | NA | H2AFV Entrez, Source | H2A histone family, member V | 18440 | -0.188 | -0.3645 | No |
| 85 | 8325 | NA | FZD8 Entrez, Source | frizzled class receptor 8 | 19170 | -0.239 | -0.3864 | No |
| 86 | 79571 | NA | GCC1 Entrez, Source | GRIP and coiled-coil domain containing 1 | 19176 | -0.239 | -0.3753 | No |
| 87 | 861 | NA | RUNX1 Entrez, Source | runt-related transcription factor 1 | 20104 | -0.340 | -0.4015 | Yes |
| 88 | 9615 | NA | GDA Entrez, Source | guanine deaminase | 20137 | -0.344 | -0.3867 | Yes |
| 89 | 64919 | NA | BCL11B Entrez, Source | B-cell CLL/lymphoma 11B (zinc finger protein) | 20272 | -0.360 | -0.3757 | Yes |
| 90 | 55137 | NA | FIGN Entrez, Source | fidgetin | 20367 | -0.373 | -0.3623 | Yes |
| 91 | 6558 | NA | SLC12A2 Entrez, Source | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 20432 | -0.381 | -0.3472 | Yes |
| 92 | 10217 | NA | CTDSPL Entrez, Source | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 20547 | -0.398 | -0.3335 | Yes |
| 93 | 140885 | NA | SIRPA Entrez, Source | signal-regulatory protein alpha | 20660 | -0.416 | -0.3189 | Yes |
| 94 | 2683 | NA | B4GALT1 Entrez, Source | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 20680 | -0.420 | -0.2999 | Yes |
| 95 | 29966 | NA | STRN3 Entrez, Source | striatin, calmodulin binding protein 3 | 20863 | -0.453 | -0.2868 | Yes |
| 96 | 4613 | NA | MYCN Entrez, Source | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 21044 | -0.494 | -0.2716 | Yes |
| 97 | 9935 | NA | MAFB Entrez, Source | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 21417 | -0.623 | -0.2590 | Yes |
| 98 | 5101 | NA | PCDH9 Entrez, Source | protocadherin 9 | 21428 | -0.628 | -0.2297 | Yes |
| 99 | 55084 | NA | SOBP Entrez, Source | sine oculis binding protein homolog (Drosophila) | 21554 | -0.704 | -0.2020 | Yes |
| 100 | 25817 | NA | FAM19A5 Entrez, Source | family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 | 21766 | -0.936 | -0.1673 | Yes |
| 101 | 7546 | NA | ZIC2 Entrez, Source | Zic family member 2 | 21936 | -1.571 | -0.1005 | Yes |
| 102 | 23092 | NA | ARHGAP26 Entrez, Source | Rho GTPase activating protein 26 | 21977 | -2.181 | 0.0010 | Yes |
