AAstretch launched 20/10/2010 at 0:21:58 alpha 0.05 data_source homo_sapiens.prot.txt explore 0 flank_length 30 flank_start 0 ignore (predicted|hypothetical|potential|ann\|---) isoform_check on patt_extrem_len 2 patt_gap_max_number 100 patt_gap_min_size 0 patt_stretch_max_size 1000 patt_stretch_min_size 5 residue Q rich_gap_tolerance auto rich_stretch_min_aa_perc 20 rich_stretch_min_size 30 rich_verbose 0 rich_win_length 5 scan 1 scanmode seed seed_gap_max_size 5 seed_seed_max_size 1000 seed_seed_min_size 5 seed_stretch_min_aa_perc 75 sync 1 tuple 1 verbose 0 Global_stat_tup_1 1322382 1279858 975000 1464507 1143644 1171101 1211014 883101 1994905 434782 1403502 243312 533417 725149 1694864 1087633 525471 450463 733980 978595 Available sequences 37067 Total AA count 20256680 Total stretches found 299 1st-M 35442 Name Len Stretches_tot Stretch_seq Stretch_len Q% pureQ_len pureQ_ratio start stop Position% lf_seq rf_seq go_func go_proc go_comp omim >prot|ENSP00000355133|cod|ENST00000361897|gene|ENSG00000198929|ann|Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein)(Nitric oxide synthase 1 adaptor protein) [Source:UniProtKB/Swiss-Prot;Acc:O75052] 506 1 QQQQQQTQ 8 87.5 6 0.75 301 308 59 LPSSSSKPPGLGTETPLSTHHQMQLLQQLL VAVAQVHLLKDQLAAEAAARLEAQARVHQL GO:0005515:protein binding;GO:0030165:PDZ domain binding;GO:0050998:nitric-oxide synthase binding; --- --- 610141: QT INTERVAL, VARIATION IN; >prot|ENSP00000338552|cod|ENST00000349655|gene|ENSG00000152795|ann|Heterogeneous nuclear ribonucleoprotein D-like (hnRPD-like protein)(hnHNRP-DL)(JKT41-binding protein)(AU-rich element RNA-binding factor)(Protein laAUF1) [Source:UniProtKB/Swiss-Prot;Acc:O14979] 244 1 QQQQQQ 6 100 6 1 197 202 80 PVKKLLESRYHQIGSGKCEIKVAQPKEVYR KGGRGAAAGGRGGTRGRGRGQQSTYGKASR GO:0000166:nucleotide binding;GO:0003677:DNA binding;GO:0003690:double-stranded DNA binding;GO:0003697:single-stranded DNA binding;GO:0003723:RNA binding;GO:0005515:protein binding;GO:0008143:poly(A) RNA binding;GO:0003676:nucleic acid binding; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0006396:RNA processing; GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0030530:heterogeneous nuclear ribonucleoprotein complex; --- >prot|ENSP00000275732|cod|ENST00000275732|gene|ENSG00000146830|ann|PERQ amino acid-rich with GYF domain-containing protein 1 (GRB10-interacting GYF protein 1) [Source:UniProtKB/Swiss-Prot;Acc:O75420] 1035 1 QQQQQQ 6 100 6 1 603 608 58 QLVSSRQLPQCALREKAALGDLTPPPPPPP LTAFLQQLQALKPPRGGDQNLLPTMSRSLS GO:0005515:protein binding; GO:0048009:insulin-like growth factor receptor signaling pathway; --- --- >prot|ENSP00000349164|cod|ENST00000356728|gene|ENSG00000143365|ann|Nuclear receptor ROR-gamma (Retinoid-related orphan receptor-gamma)(Nuclear receptor RZR-gamma)(Nuclear receptor subfamily 1 group F member 3) [Source:UniProtKB/Swiss-Prot;Acc:P51449] 497 1 QKQLQQRQQQQQ 12 75 5 0.416666666666667 98 109 19 QKCLALGMSRDAVKFGRMSKKQRDSLHAEV EPVVKTPPAGAQGADTLTYTLGLPDGQLPL GO:0003677:DNA binding;GO:0004879:ligand-dependent nuclear receptor activity;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0003707:steroid hormone receptor activity;GO:0008270:zinc ion binding;GO:0043565:sequence-specific DNA binding;GO:0004887:thyroid hormone receptor activity; GO:0006355:regulation of transcription, DNA-dependent;GO:0006468:protein amino acid phosphorylation;GO:0030154:cell differentiation;GO:0046632:alpha-beta T cell differentiation;GO:0033077:T cell differentiation in thymus;GO:0048535:lymph node development;GO:0048537:mucosal-associated lymphoid tissue development; GO:0005634:nucleus; --- >prot|ENSP00000383847|cod|ENST00000401069|gene|ENSG00000169218|ann|R-spondin-1 Precursor (Roof plate-specific spondin-1)(hRspo1) [Source:UniProtKB/Swiss-Prot;Acc:Q2MKA7] 263 1 QQQQQQQ 7 100 7 1 245 251 93 GGQGRRENANRNLARKESKEAGAGSRRRKG GTVGPLTSAGPA --- --- GO:0005615:extracellular space;GO:0005634:nucleus; --- >prot|ENSP00000361027|cod|ENST00000371959|gene|ENSG00000126016|ann|Angiomotin [Source:UniProtKB/Swiss-Prot;Acc:Q4VCS5] 1084 2 QQQQQQQQQ 9 100 9 1 376 384 34 SAHLPRPQQHFLPNQAHQGDHYRLSQPGLS HHHHHHHQQQQQQQPQQQPGEAYSAMPRAQ --- GO:0006935:chemotaxis;GO:0001702:gastrulation with mouth forming second;GO:0001570:vasculogenesis;GO:0001701:in utero embryonic development;GO:0042074:cell migration involved in gastrulation;GO:0040019:positive regulation of embryonic development; GO:0030027:lamellipodium; --- >prot|ENSP00000361027|cod|ENST00000371959|gene|ENSG00000126016|ann|Angiomotin [Source:UniProtKB/Swiss-Prot;Acc:Q4VCS5] 1084 2 QQQQQQQPQQQ 11 90.9090909090909 7 0.636363636363636 392 402 36 HQGDHYRLSQPGLSQQQQQQQQQHHHHHHH PGEAYSAMPRAQPSSASYQPVPADPFAIVS --- GO:0006935:chemotaxis;GO:0001702:gastrulation with mouth forming second;GO:0001570:vasculogenesis;GO:0001701:in utero embryonic development;GO:0042074:cell migration involved in gastrulation;GO:0040019:positive regulation of embryonic development; GO:0030027:lamellipodium; --- >prot|ENSP00000357870|cod|ENST00000368876|gene|ENSG00000123505|ann|S-adenosylmethionine decarboxylase proenzyme Precursor (AdoMetDC)(SAMDC)(EC 4.1.1.50) [Contains S-adenosylmethionine decarboxylase alpha chain;S-adenosylmethionine decarboxylase beta chain] [Source:UniProtKB/Swiss-Prot;Acc:P17707] 265 1 QQQQQ 5 100 5 1 260 264 98 PQKIEGFKRLDCQSAMFNDYNFVFTSFAKK S GO:0004014:adenosylmethionine decarboxylase activity;GO:0016829:lyase activity; GO:0006597:spermine biosynthetic process;GO:0008295:spermidine biosynthetic process; GO:0005575:cellular_component; --- >prot|ENSP00000329436|cod|ENST00000329800|gene|ENSG00000133069|ann|Transmembrane and coiled-coil domains protein 2 (Cerebral protein 11) [Source:UniProtKB/Swiss-Prot;Acc:O75069] 469 1 QQQQQQVVQ 9 77.7777777777778 6 0.666666666666667 382 390 81 EKVAYQSYERARDIQEAVESCLTRVTKLEL LEGVENANARALLGKFINVILALMAVLLVF GO:0005515:protein binding; GO:0016192:vesicle-mediated transport; GO:0016020:membrane;GO:0016021:integral to membrane; --- >prot|ENSP00000370408|cod|ENST00000381020|gene|ENSG00000165556|ann|Homeobox protein CDX-2 (Caudal-type homeobox protein 2)(CDX-3) [Source:UniProtKB/Swiss-Prot;Acc:Q99626] 313 1 QQQQQQQPPQ 10 80 7 0.7 250 259 79 AATLGLSERQVKIWFQNRRAKERKINKKKL PPPPPPQPPQPQPGPLRSVPEPLSPVSSLQ GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0003714:transcription corepressor activity;GO:0005515:protein binding;GO:0043565:sequence-specific DNA binding;GO:0050825:ice binding;GO:0004969:histamine receptor activity;GO:0030528:transcription regulator activity; GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0001568:blood vessel development;GO:0001824:blastocyst development;GO:0001829:trophectodermal cell differentiation;GO:0001890:placenta development;GO:0006355:regulation of transcription, DNA-dependent;GO:0007389:pattern specification process;GO:0035019:somatic stem cell maintenance;GO:0045597:positive regulation of cell differentiation;GO:0042309:homoiothermy;GO:0050826:response to freezing;GO:0007186:G-protein coupled receptor protein signaling pathway;GO:0007275:multicellular organismal development;GO:0045449:regulation of transcription;GO:0030154:cell differentiation; GO:0000794:condensed nuclear chromosome;GO:0016021:integral to membrane;GO:0005634:nucleus;GO:0017053:transcriptional repressor complex; --- >prot|ENSP00000290583|cod|ENST00000290583|gene|ENSG00000159409|ann|CUG-BP- and ETR-3-like factor 3 (CELF-3)(Bruno-like protein 1)(RNA-binding protein BRUNOL-1)(ELAV-type RNA-binding protein 1)(ETR-1)(Trinucleotide repeat-containing gene 4 protein)(Expanded repeat domain protein CAG/CTG 4)(CAG repeat protein 4) [Source:UniProtKB/Swiss-Prot;Acc:Q5SZQ8] 465 1 QQPPPPPQQQQQQQQQQQQQQQ 22 77.2727272727273 15 0.681818181818182 352 373 75 YAGMQHYTAAYPAAYSLVAPAFPQPPALVA REGPDGCNIFIYHLPQEFTDSEILQMFVPF GO:0003676:nucleic acid binding;GO:0003723:RNA binding; GO:0030317:sperm motility;GO:0007283:spermatogenesis; GO:0005634:nucleus;GO:0005737:cytoplasm; --- >prot|ENSP00000346372|cod|ENST00000354396|gene|ENSG00000143437|ann|Aryl hydrocarbon receptor nuclear translocator (ARNT protein)(Dioxin receptor, nuclear translocator)(Hypoxia-inducible factor 1 beta)(HIF-1 beta) [Source:UniProtKB/Swiss-Prot;Acc:P27540] 787 1 QQQQQ 5 100 5 1 503 507 63 PTLSNTIQRPQLGPTANLPLEMGSGQLAPR TELDMVPGRDGLASYNHSQVVQPVTTTGPE GO:0004871:signal transducer activity;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0030528:transcription regulator activity; GO:0007165:signal transduction;GO:0006355:regulation of transcription, DNA-dependent;GO:0045449:regulation of transcription; GO:0005634:nucleus; --- >prot|ENSP00000376394|cod|ENST00000392618|gene|ENSG00000160679|ann|Uncharacterized protein C1orf77 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y3Y2] 248 1 QQQQQ 5 100 5 1 42 46 16 KSTTKMSLNERFTNMLKNKQPTPVNIRASM LASARNRRLAQQMENRPSVQAALKLKQSLK GO:0005515:protein binding; --- --- --- >prot|ENSP00000366843|cod|ENST00000377617|gene|ENSG00000204842|ann|Ataxin-2 (Spinocerebellar ataxia type 2 protein)(Trinucleotide repeat-containing gene 13 protein) [Source:UniProtKB/Swiss-Prot;Acc:Q99700] 1313 1 QQQQQQQQQQQQQQQQQQQQQQQ 23 100 23 1 166 188 12 SGVSLARPAPGCPRPACEPVYGPLTMSLKP PPPAAANVRKPGGSGLLASPAAAPSPSSSS GO:0003723:RNA binding;GO:0008022:protein C-terminus binding; GO:0006417:regulation of translation;GO:0008219:cell death;GO:0016070:RNA metabolic process;GO:0033962:cytoplasmic mRNA processing body assembly;GO:0034063:stress granule assembly;GO:0050658:RNA transport; GO:0005737:cytoplasm;GO:0005794:Golgi apparatus;GO:0005802:trans-Golgi network;GO:0005844:polysome;GO:0010494:stress granule;GO:0048471:perinuclear region of cytoplasm; 183090: SPINOCEREBELLAR ATAXIA 2; >prot|ENSP00000357675|cod|ENST00000368686|gene|ENSG00000160679|ann|Uncharacterized protein C1orf77 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y3Y2] 101 1 QQQQQ 5 100 5 1 2 6 1 MQQQQQLASARNRRLAQQMENRPSVQAALK LASARNRRLAQQMENRPSVQAALKLKQKSL GO:0005515:protein binding; --- --- --- >prot|ENSP00000313327|cod|ENST00000353341|gene|ENSG00000138668|ann|Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0)(AU-rich element RNA-binding protein 1) [Source:UniProtKB/Swiss-Prot;Acc:Q14103] 306 1 QYQQQQQ 7 85.7142857142857 5 0.714285714285714 262 268 85 EEEPVKKIMEKKYHNVGLSKCEIKVAMSKE WGSRGGFAGRARGRGGDQQSGYGKVSRRGG GO:0000166:nucleotide binding;GO:0003677:DNA binding;GO:0003723:RNA binding;GO:0005515:protein binding;GO:0016563:transcription activator activity;GO:0042162:telomeric DNA binding;GO:0050825:ice binding;GO:0003676:nucleic acid binding; GO:0000398:nuclear mRNA splicing, via spliceosome;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0006396:RNA processing;GO:0006401:RNA catabolic process;GO:0008150:biological_process;GO:0042309:homoiothermy;GO:0050826:response to freezing; GO:0005634:nucleus;GO:0005694:chromosome;GO:0030530:heterogeneous nuclear ribonucleoprotein complex; --- >prot|ENSP00000369996|cod|ENST00000380622|gene|ENSG00000123594|ann|Putative ataxin-3-like protein (EC 3.4.22.-)(Machado-Joseph disease protein 1-like) [Source:UniProtKB/Swiss-Prot;Acc:Q9H3M9] 355 1 QQEQKQQQQQ 10 80 5 0.5 291 300 81 NTSQDLPKTSCVTPASEQPKKIKEDYFEKH SDLPGHSSYLHERPTTSSRAIESDLSDDIS GO:0016787:hydrolase activity; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent; GO:0005634:nucleus; --- >prot|ENSP00000320374|cod|ENST00000325721|gene|ENSG00000148337|ann|Cip1-interacting zinc finger protein (CDKN1A-interacting zinc finger protein 1)(Nuclear protein NP94)(Zinc finger protein 356) [Source:UniProtKB/Swiss-Prot;Acc:Q9ULV3] 869 1 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQ 41 75.609756097561 6 0.146341463414634 4 44 0 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQL SPPQAPLPMAVSRGLPPQQPQQPLLNLQGT GO:0003676:nucleic acid binding;GO:0008270:zinc ion binding;GO:0046872:metal ion binding; --- GO:0005622:intracellular;GO:0005634:nucleus; --- >prot|ENSP00000285106|cod|ENST00000285106|gene|ENSG00000154832|ann|CpG-binding protein (PHD finger and CXXC domain-containing protein 1)(CXXC-type zinc finger protein 1) [Source:UniProtKB/Swiss-Prot;Acc:Q9P0U4] 656 1 QHHQQQQQQ 9 77.7777777777778 6 0.666666666666667 153 161 23 GSGTGVGAMLARGSASPHKSSPQPLVATPS IKRSARMCGECEACRRTEDCGHCDFCRDMK GO:0003677:DNA binding;GO:0005515:protein binding;GO:0008270:zinc ion binding;GO:0016563:transcription activator activity;GO:0045322:unmethylated CpG binding;GO:0046872:metal ion binding; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent; GO:0005634:nucleus;GO:0016363:nuclear matrix;GO:0016607:nuclear speck; --- >prot|ENSP00000381543|cod|ENST00000398532|gene|ENSG00000188895|ann|Male-specific lethal 1 homolog (MSL-1)(Male-specific lethal 1-like 1)(MSL1-like 1)(Male-specific lethal-1 homolog 1) [Source:UniProtKB/Swiss-Prot;Acc:Q68DK7] 614 1 QQQQQLQ 7 85.7142857142857 5 0.714285714285714 235 241 38 SPLGGGGGSGASSQAACLKQILLLQLDLIE AKEKEIEELKSERDTLLARIERMERRMQLV --- GO:0016568:chromatin modification; GO:0005634:nucleus; --- >prot|ENSP00000379637|cod|ENST00000396348|gene|ENSG00000100207|ann|Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein)(SPRE-binding protein)(Nuclear factor SPBP)(AR1) [Source:UniProtKB/Swiss-Prot;Acc:Q9UGU0] 1938 3 QQQQQQVQQ 9 88.8888888888889 6 0.666666666666667 174 182 8 SGLGGVSHYQQDYTGPFSPGSAQYQQQASS LRQQLYQSHQPLPQATGQPASSSSHLQPMQ GO:0005515:protein binding;GO:0008270:zinc ion binding; --- --- --- >prot|ENSP00000379637|cod|ENST00000396348|gene|ENSG00000100207|ann|Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein)(SPRE-binding protein)(Nuclear factor SPBP)(AR1) [Source:UniProtKB/Swiss-Prot;Acc:Q9UGU0] 1938 3 QQGQQQQQPQQQQ 13 84.6153846153846 5 0.384615384615385 310 322 15 NAQAYGTQSNYSYQPQSMKNFEQAKIPQGT HPSQHVMQYTNAATKLPLQSQVGQYNQPEV GO:0005515:protein binding;GO:0008270:zinc ion binding; --- --- --- >prot|ENSP00000379637|cod|ENST00000396348|gene|ENSG00000100207|ann|Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein)(SPRE-binding protein)(Nuclear factor SPBP)(AR1) [Source:UniProtKB/Swiss-Prot;Acc:Q9UGU0] 1938 3 QQQQQKEQ 8 75 5 0.625 1770 1777 91 KRATEMQSKVKVRHKSASNGSKTDTEEEEE RSLAAHPRFKRRHRSEDCGGGPRSLSRGLP GO:0005515:protein binding;GO:0008270:zinc ion binding; --- --- --- >prot|ENSP00000385835|cod|ENST00000407029|gene|ENSG00000196588|ann|MKL/myocardin-like protein 1 (Myocardin-related transcription factor A)(MRTF-A)(Megakaryoblastic leukemia 1 protein)(Megakaryocytic acute leukemia protein) [Source:UniProtKB/Swiss-Prot;Acc:Q969V6] 931 1 QQQQQ 5 100 5 1 277 281 29 KQDRGAPPMDSSYAKILQQQQLFLQLQILN HHNYQAILPAPPKSAGEALGSSGTPPVRSL GO:0003676:nucleic acid binding;GO:0005249:voltage-gated potassium channel activity; GO:0006813:potassium ion transport; GO:0016021:integral to membrane; --- >prot|ENSP00000360266|cod|ENST00000371222|gene|ENSG00000177606|ann|Transcription factor AP-1 (Activator protein 1)(AP1)(Proto-oncogene c-jun)(V-jun avian sarcoma virus 17 oncogene homolog)(p39) [Source:UniProtKB/Swiss-Prot;Acc:P05412] 331 1 QPQQQQQ 7 85.7142857142857 5 0.714285714285714 200 206 60 YANLSNFNPGALSSGGGAPSYGAAGLAFPA PPHHLPQQMPVQHPRLQALKEEPQTVPEMP GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0003702:RNA polymerase II transcription factor activity;GO:0005100:Rho GTPase activator activity;GO:0008134:transcription factor binding;GO:0046332:SMAD binding;GO:0046983:protein dimerization activity;GO:0003677:DNA binding;GO:0043565:sequence-specific DNA binding;GO:0005515:protein binding; GO:0006355:regulation of transcription, DNA-dependent;GO:0007184:SMAD protein nuclear translocation;GO:0009987:cellular process;GO:0031953:negative regulation of protein amino acid autophosphorylation;GO:0035026:leading edge cell differentiation;GO:0042493:response to drug;GO:0045941:positive regulation of transcription;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0051726:regulation of cell cycle;GO:0045449:regulation of transcription;GO:0008285:negative regulation of cell proliferation; GO:0000228:nuclear chromosome;GO:0005829:cytosol;GO:0005634:nucleus;GO:0005667:transcription factor complex; --- >prot|ENSP00000345702|cod|ENST00000341376|gene|ENSG00000001167|ann|Nuclear transcription factor Y subunit alpha (Nuclear transcription factor Y subunit A)(NF-YA)(CAAT-box DNA-binding protein subunit A) [Source:UniProtKB/Swiss-Prot;Acc:P23511] 347 1 QIQQQQQ 7 85.7142857142857 5 0.714285714285714 21 27 6 MEQYTANSNSSTEQIVVQAGQIQQQQQGGV GGVTAVQLQTEAQVASASGQQVQTLQVVQG GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0003677:DNA binding;GO:0005515:protein binding;GO:0016563:transcription activator activity; GO:0006355:regulation of transcription, DNA-dependent;GO:0045893:positive regulation of transcription, DNA-dependent;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0006357:regulation of transcription from RNA polymerase II promoter; GO:0005634:nucleus;GO:0016602:CCAAT-binding factor complex; --- >prot|ENSP00000249883|cod|ENST00000249883|gene|ENSG00000114019|ann|Angiomotin-like protein 2 (Leman coiled-coil protein)(LCCP) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y2J4] 780 1 QQQQQYQ 7 85.7142857142857 5 0.714285714285714 257 263 32 TDPRYRARGSPHFQHAEVRILQAQVPPVFL YLQQSQEHPPPPHPAALGHGPLSSLSPPAV GO:0042802:identical protein binding;GO:0005515:protein binding; --- GO:0005923:tight junction; --- >prot|ENSP00000338371|cod|ENST00000335727|gene|ENSG00000100354|ann|Trinucleotide repeat-containing gene 6B protein [Source:UniProtKB/Swiss-Prot;Acc:Q9UPQ9] 1723 2 QQQQQQQLLQNQ 12 75 7 0.583333333333333 1177 1188 68 VGPQLSPQQIAMLSQLPQIPQFQLACQLLL RKISQAVRQQQEQQLARMVSALQQQQQQQQ GO:0003676:nucleic acid binding; --- --- --- >prot|ENSP00000338371|cod|ENST00000335727|gene|ENSG00000100354|ann|Trinucleotide repeat-containing gene 6B protein [Source:UniProtKB/Swiss-Prot;Acc:Q9UPQ9] 1723 2 QQQQQQQQRQ 10 90 8 0.8 1211 1220 70 QQQLLQNQRKISQAVRQQQEQQLARMVSAL PGMKHSPSHPVGPKPHLDNMVPNALNVGLP GO:0003676:nucleic acid binding; --- --- --- >prot|ENSP00000348415|cod|ENST00000356106|gene|ENSG00000141052|ann|Myocardin [Source:UniProtKB/Swiss-Prot;Acc:Q8IZQ8] 890 1 QQQQQQQ 7 100 7 1 208 214 23 KAEKSPPPMDSAYARLLQQQQLFLQLQILS HRFSYLGMHQAQLKEPNEQMVRNPNSSSTP GO:0003676:nucleic acid binding; --- --- --- >prot|ENSP00000365627|cod|ENST00000376444|gene|ENSG00000068400|ann|GRIP1-associated protein 1 (GRASP-1) [Source:UniProtKB/Swiss-Prot;Acc:Q4V328] 796 1 QQQQQEQ 7 85.7142857142857 5 0.714285714285714 492 498 61 TVEELQAQVHSMDGAKGWFERRLKEAEESL EEALKQCREQHAAELKGKEEELQDVRDQLE GO:0003674:molecular_function; GO:0008150:biological_process; GO:0005575:cellular_component;GO:0005769:early endosome; --- >prot|ENSP00000381509|cod|ENST00000398496|gene|ENSG00000130723|ann|Protein BAT2-like (HLA-B-associated transcript 2-like) [Source:UniProtKB/Swiss-Prot;Acc:Q5JSZ5] 178 1 QRQQQQQQQ 9 88.8888888888889 7 0.777777777777778 169 177 94 AQSNSSEEEAREAGSPAQEFKYQKSLPPRF E --- --- --- --- >prot|ENSP00000299004|cod|ENST00000299004|gene|ENSG00000166025|ann|Angiomotin-like protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q8IY63] 590 1 QQQQQQQQ 8 100 8 1 188 195 31 KQVRSTQPQQNNEELPTYEEAKAQSQFFRG GAVGHGYYMAGGTSQKSRTEGRPTVNRANS GO:0042802:identical protein binding;GO:0000166:nucleotide binding; --- GO:0005737:cytoplasm;GO:0005923:tight junction;GO:0030054:cell junction; --- >prot|ENSP00000373899|cod|ENST00000389247|gene|ENSG00000178385|ann|Pleckstrin homology domain-containing family M member 3 [Source:UniProtKB/Swiss-Prot;Acc:Q6ZWE6] 717 1 QQQQQQQ 7 100 7 1 169 175 23 ETSTFKPGHARSRSDITQVDWRVVLKTTPL PLLQGPHVTRPSFLLPSPNKIEDAQGNTEH GO:0008270:zinc ion binding;GO:0019992:diacylglycerol binding;GO:0046872:metal ion binding;GO:0005515:protein binding; GO:0007242--- --- --- >prot|ENSP00000304411|cod|ENST00000307660|gene|ENSG00000135457|ann|Alpha-globin transcription factor CP2 (Transcription factor LSF)(SAA3 enhancer factor) [Source:UniProtKB/Swiss-Prot;Acc:Q12800] 450 1 QQQQQQQQQQ 10 100 10 1 353 362 78 GIRLFNALKGRMVRPRLTIYVCQESLQLRE KHEDGDSNGTFFVYHAIYLEELTAVELTEK GO:0003700:sequence-specific DNA binding transcription factor activity; GO:0006350:transcription;GO:0006357:regulation of transcription from RNA polymerase II promoter; GO:0005575:cellular_component;GO:0005634:nucleus; --- >prot|ENSP00000316454|cod|ENST00000320580|gene|ENSG00000175115|ann|Phosphofurin acidic cluster sorting protein 1 (PACS-1) [Source:UniProtKB/Swiss-Prot;Acc:Q6VY07] 963 1 QQQQQQPPQQ 10 80 6 0.6 35 44 3 GGAGGGPGGAGGGSGQRGSGVAQSPQQPPP PTPPKLAQATSSSSSTSAAAASSSSSSTST GO:0005515:protein binding; GO:0000042:protein targeting to Golgi;GO:0044419:interspecies interaction between organisms; GO:0005829:cytosol;GO:0005794:Golgi apparatus;GO:0030137:COPI-coated vesicle; --- >prot|ENSP00000339110|cod|ENST00000340660|gene|ENSG00000066427|ann|ataxin 3 isoform 1 [Source:RefSeq peptide;Acc:NP_004984] 306 1 QQQKQQQQQQQQQQ 14 92.8571428571429 10 0.714285714285714 237 250 77 RNISQDMTQTSGTNLTSEELRKRREAYFEK GDLSGQSSHPCERPATSSGALGSDLGDAMS --- --- --- --- >prot|ENSP00000335578|cod|ENST00000334384|gene|ENSG00000186103|ann|Arginine-fifty homeobox [Source:UniProtKB/Swiss-Prot;Acc:A6NJG6] 315 1 QQQQQ 5 100 5 1 136 140 43 NLQEKLALRLDLPESTVKVWFRNRRFKLKK SAKQRNQILPSKKNVPTSPRTSPSPYAFSP GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0043565:sequence-specific DNA binding;GO:0030528:transcription regulator activity; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent; GO:0005634:nucleus; --- >prot|ENSP00000378190|cod|ENST00000394700|gene|ENSG00000143437|ann|Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9HBZ2] 740 1 QQQQQ 5 100 5 1 455 459 61 TSSFTFQNPYSDEIEYIICTNTNVKPLTYR TELDMVPGRDGLASYNHSQVVQPVTTTGPE GO:0004871:signal transducer activity;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0030528:transcription regulator activity; GO:0007165:signal transduction;GO:0006355:regulation of transcription, DNA-dependent;GO:0045449:regulation of transcription; GO:0005634:nucleus; --- >prot|ENSP00000319087|cod|ENST00000352853|gene|ENSG00000250096|ann|Runt-related transcription factor 2 (Core-binding factor subunit alpha-1)(CBF-alpha-1)(Acute myeloid leukemia 3 protein)(Oncogene AML-3)(Polyomavirus enhancer-binding protein 2 alpha A subunit)(PEBP2-alpha A)(PEA2-alpha A)(SL3-3 enhancer factor 1 alpha A subunit)(SL3/AKV core-binding factor alpha A subunit)(Osteoblast-specific transcription factor 2)(OSF-2) [Source:UniProtKB/Swiss-Prot;Acc:Q13950] 507 1 QQQQQQQQQQQQQQQQQQQQQQQ 23 100 23 1 35 57 6 VDPSTSRRFSPPSSSLQPGKMSDVSPVVAA EAAAAAAAAAAAAAAAAAVPRLRPPHDNRT GO:0003677:DNA binding;GO:0005524:ATP binding;GO:0050825:ice binding;GO:0003700:sequence-specific DNA binding transcription factor activity; GO:0006355:regulation of transcription, DNA-dependent;GO:0042309:homoiothermy;GO:0050826:response to freezing;GO:0045449:regulation of transcription;GO:0045778:positive regulation of ossification; GO:0005634:nucleus; 119600: CLEIDOCRANIAL DYSPLASIA; >prot|ENSP00000312267|cod|ENST00000307824|gene|ENSG00000172765|ann|Transmembrane and coiled-coil domains protein 1 [Source:UniProtKB/Swiss-Prot;Acc:O94876] 329 1 QQQQQQVVQ 9 77.7777777777778 6 0.666666666666667 241 249 73 EKIAYQSYERARDIQEALEACQTRISKMEL LEGLENATARNLLGKLINILLAVMAVLLVF --- --- GO:0016020:membrane;GO:0016021:integral to membrane; --- >prot|ENSP00000378432|cod|ENST00000394981|gene|ENSG00000138722|ann|Multimerin-1 Precursor (Endothelial cell multimerin)(EMILIN-4)(Elastin microfibril interface located protein 4)(Elastin microfibril interfacer 4) [Source:UniProtKB/Swiss-Prot;Acc:Q13201] 531 1 QQQQQ 5 100 5 1 275 279 51 KCQLRAQEQQSLIHTNQAESHTAVGRGVAE GCGDPEVMQKMTDQVNYQAMKLTLLQKKID GO:0005509:calcium ion binding; GO:0007155:cell adhesion;GO:0007596:blood coagulation; GO:0005576:extracellular region;GO:0031093:platelet alpha granule lumen; --- >prot|ENSP00000355959|cod|ENST00000366992|gene|ENSG00000143493|ann|Integrator complex subunit 7 (Int7) [Source:UniProtKB/Swiss-Prot;Acc:Q9NVH2] 942 1 QQQQAQQPLQQQQQ 14 78.5714285714286 5 0.357142857142857 922 935 97 DANGIVWKTGPRTTIFVKSLEDPYSQQIRL RNAYTRF GO:0005515:protein binding;GO:0005488:binding; GO:0016180:snRNA processing; GO:0005634:nucleus;GO:0032039:integrator complex; --- >prot|ENSP00000385069|cod|ENST00000403559|gene|ENSG00000128573|ann|Forkhead box protein P2 (CAG repeat protein 44)(Trinucleotide repeat-containing gene 10 protein) [Source:UniProtKB/Swiss-Prot;Acc:O15409] 606 1 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQ 78 78.2051282051282 39 0.5 45 122 7 PQQMQQILQQQVLSPQQLQALLQQQQAVML HLLSLQRQGLISIPPGQAALPVQSLPQAGL GO:0008270:zinc ion binding; --- GO:0005622:intracellular; --- >prot|ENSP00000379915|cod|ENST00000396684|gene|ENSG00000111676|ann|Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein) [Source:UniProtKB/Swiss-Prot;Acc:P54259] 1190 1 QQQQQQQQQQQQQQQQQQQ 19 100 19 1 484 502 40 NSNAHPGPFPPSTGAQSTAHPPVSTHHHHH HHGNSGPPPPGAFPHPLEGGSSHHAHPYAM GO:0003714:transcription corepressor activity;GO:0019904:protein domain specific binding;GO:0050827:toxin receptor binding; GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0007417:central nervous system development;GO:0008219:cell death;GO:0009404:toxin metabolic process; GO:0005634:nucleus;GO:0005737:cytoplasm; 125370: DENTATORUBRAL-PALLIDOLUYSIAN ATROPHY; >prot|ENSP00000318721|cod|ENST00000318779|gene|ENSG00000114861|ann|Forkhead box protein P1 [Source:UniProtKB/Swiss-Prot;Acc:Q9H334] 114 1 QQQQQQ 6 100 6 1 55 60 48 HLLECGGLREGRSNGETPAVDIGAADLAHA WHLINHQPSRSPSSWLKRLISSPWELEVLQ GO:0008270:zinc ion binding; --- GO:0005622:intracellular; --- >prot|ENSP00000379644|cod|ENST00000396356|gene|ENSG00000110693|ann|Transcription factor SOX-6 [Source:UniProtKB/Swiss-Prot;Acc:P35712] 808 1 QQQQQ 5 100 5 1 514 518 63 LNSPALFGDQDTVMKAIQEARKMREQIQRE PHGVDGKLSSINNMGLNSCRNEKERTRFEN GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0003677:DNA binding; GO:0006325:chromatin organization;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0007275:multicellular organismal development;GO:0007517:muscle organ development; GO:0005634:nucleus; --- >prot|ENSP00000273317|cod|ENST00000273317|gene|ENSG00000144791|ann|LIM domain-containing protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9UGP4] 676 1 QQQQQQLLQ 9 77.7777777777778 6 0.666666666666667 58 66 8 LFRVDKGAGNNPEFEETRRVFATKMAKIHL EETLPRGSRGPVNGGGRLGPQARWEVVGSK GO:0005515:protein binding;GO:0008270:zinc ion binding;GO:0046872:metal ion binding; GO:0006355:regulation of transcription, DNA-dependent;GO:0007165:signal transduction;GO:0007275:multicellular organismal development; --- --- >prot|ENSP00000337202|cod|ENST00000338042|gene|ENSG00000068305|ann|Myocyte-specific enhancer factor 2A (Serum response factor-like protein 1) [Source:UniProtKB/Swiss-Prot;Acc:Q02078] 505 1 QQQQQQQQQQQ 11 100 11 1 418 428 82 SNLSINTNQNISIKSEPISPPRDRMTPSGF PPPPPQPQPQPPQPQPRQEMGRSPVDSLSS GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0043565:sequence-specific DNA binding;GO:0005515:protein binding;GO:0003677:DNA binding;GO:0019901:protein kinase binding;GO:0016563:transcription activator activity; GO:0006355:regulation of transcription, DNA-dependent;GO:0045941:positive regulation of transcription; GO:0005634:nucleus; 608320: CORONARY ARTERY DISEASE, AUTOSOMAL DOMINANT, 1; >prot|ENSP00000265069|cod|ENST00000265069|gene|ENSG00000056097|ann|Zinc finger RNA-binding protein (hZFR)(M-phase phosphoprotein homolog) [Source:UniProtKB/Swiss-Prot;Acc:Q96KR1] 1074 1 QQQQQQQKQ 9 88.8888888888889 7 0.777777777777778 281 289 26 ATYSTTAVTYSGTSYSGYEAAVYSAASSYY AAAAAAAAAATAAWTGTTFTKKAPFQNKQL GO:0050825:ice binding;GO:0003735:structural constituent of ribosome;GO:0003677:DNA binding;GO:0004879:ligand-dependent nuclear receptor activity;GO:0003676:nucleic acid binding;GO:0008270:zinc ion binding; GO:0042309:homoiothermy;GO:0050826:response to freezing;GO:0006412:translation;GO:0006355:regulation of transcription, DNA-dependent; GO:0005622:intracellular;GO:0005840:ribosome;GO:0005634:nucleus; --- >prot|ENSP00000273668|cod|ENST00000273668|gene|ENSG00000145088|ann|ELL-associated factor 2 (Testosterone-regulated apoptosis inducer and tumor suppressor protein) [Source:UniProtKB/Swiss-Prot;Acc:Q96CJ1] 260 1 QQQQQ 5 100 5 1 126 130 48 GECRLEKLSSNITVKKTRVEGSSKIQYRKE MWNSARTPNLVKHSPSEDKMSPASPIDDIE GO:0005515:protein binding;GO:0016563:transcription activator activity; GO:0006355:regulation of transcription, DNA-dependent;GO:0006915:apoptosis;GO:0045941:positive regulation of transcription; GO:0005634:nucleus;GO:0005654:nucleoplasm;GO:0016607:nuclear speck; --- >prot|ENSP00000268489|cod|ENST00000268489|gene|ENSG00000140836|ann|Zinc finger homeobox protein 3 (Zinc finger homeodomain protein 3)(ZFH-3)(Alpha-fetoprotein enhancer-binding protein)(AT motif-binding factor)(AT-binding transcription factor 1) [Source:UniProtKB/Swiss-Prot;Acc:Q15911] 3703 4 QQQQQQQQQQQQQQQQQQQAQ 21 95.2380952380952 19 0.904761904761905 1723 1743 46 LGNPIGANIASPSEPKEANRKKLADMIASR TLAQAQAQVQAHLQQELQQQAALIQSQLFN GO:0003705:RNA polymerase II transcription factor activity, enhancer binding;GO:0008270:zinc ion binding;GO:0016564:transcription repressor activity;GO:0043565:sequence-specific DNA binding;GO:0046872:metal ion binding;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0003676:nucleic acid binding;GO:0005199:structural constituent of cell wall;GO:0030528:transcription regulator activity; GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0006355:regulation of transcription, DNA-dependent;GO:0031424:keratinization; GO:0005622:intracellular;GO:0005739:mitochondrion;GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0005667:transcription factor complex; 176807: PROSTATE CANCER; >prot|ENSP00000268489|cod|ENST00000268489|gene|ENSG00000140836|ann|Zinc finger homeobox protein 3 (Zinc finger homeodomain protein 3)(ZFH-3)(Alpha-fetoprotein enhancer-binding protein)(AT motif-binding factor)(AT-binding transcription factor 1) [Source:UniProtKB/Swiss-Prot;Acc:Q15911] 3703 4 QQPPQQQQQQQQPQVQQ 17 76.4705882352941 8 0.470588235294118 3193 3209 86 GLPTSGLPNKPSSASLSSPTPAQATMAMGP PPPPPAAQPPPTPQLPLQQQQQRKDKDSEK GO:0003705:RNA polymerase II transcription factor activity, enhancer binding;GO:0008270:zinc ion binding;GO:0016564:transcription repressor activity;GO:0043565:sequence-specific DNA binding;GO:0046872:metal ion binding;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0003676:nucleic acid binding;GO:0005199:structural constituent of cell wall;GO:0030528:transcription regulator activity; GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0006355:regulation of transcription, DNA-dependent;GO:0031424:keratinization; GO:0005622:intracellular;GO:0005739:mitochondrion;GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0005667:transcription factor complex; 176807: PROSTATE CANCER; >prot|ENSP00000268489|cod|ENST00000268489|gene|ENSG00000140836|ann|Zinc finger homeobox protein 3 (Zinc finger homeodomain protein 3)(ZFH-3)(Alpha-fetoprotein enhancer-binding protein)(AT motif-binding factor)(AT-binding transcription factor 1) [Source:UniProtKB/Swiss-Prot;Acc:Q15911] 3703 4 QQQQQ 5 100 5 1 3227 3231 87 QQQQQQQQPQVQQPPPPPAAQPPPTPQLPL RKDKDSEKVKEKEKAHKGKGEPLPVPKKEK GO:0003705:RNA polymerase II transcription factor activity, enhancer binding;GO:0008270:zinc ion binding;GO:0016564:transcription repressor activity;GO:0043565:sequence-specific DNA binding;GO:0046872:metal ion binding;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0003676:nucleic acid binding;GO:0005199:structural constituent of cell wall;GO:0030528:transcription regulator activity; GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0006355:regulation of transcription, DNA-dependent;GO:0031424:keratinization; GO:0005622:intracellular;GO:0005739:mitochondrion;GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0005667:transcription factor complex; 176807: PROSTATE CANCER; >prot|ENSP00000268489|cod|ENST00000268489|gene|ENSG00000140836|ann|Zinc finger homeobox protein 3 (Zinc finger homeodomain protein 3)(ZFH-3)(Alpha-fetoprotein enhancer-binding protein)(AT motif-binding factor)(AT-binding transcription factor 1) [Source:UniProtKB/Swiss-Prot;Acc:Q15911] 3703 4 QQQQQRQLQQQQQQKVQQQQ 20 80 6 0.3 3376 3395 91 PALSQALMGLSPGSLLQQYQQYQQSLQEAI PKASQTPVPPGAPSPDKDPAKESPKPEEQK GO:0003705:RNA polymerase II transcription factor activity, enhancer binding;GO:0008270:zinc ion binding;GO:0016564:transcription repressor activity;GO:0043565:sequence-specific DNA binding;GO:0046872:metal ion binding;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0003676:nucleic acid binding;GO:0005199:structural constituent of cell wall;GO:0030528:transcription regulator activity; GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0006355:regulation of transcription, DNA-dependent;GO:0031424:keratinization; GO:0005622:intracellular;GO:0005739:mitochondrion;GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0005667:transcription factor complex; 176807: PROSTATE CANCER; >prot|ENSP00000345255|cod|ENST00000348340|gene|ENSG00000165084|ann|Uncharacterized protein C8orf34 (Protein VEST-1) [Source:UniProtKB/Swiss-Prot;Acc:Q49A92] 287 1 QQQQQ 5 100 5 1 239 243 83 RSKNDQWESEDSGSSPAGSLKMEPKNKGLK HKKLLAAMLSQDSFESIHSPTPSVTEEDID --- --- --- --- >prot|ENSP00000339165|cod|ENST00000341009|gene|ENSG00000048052|ann|Histone deacetylase 9 (HD9)(EC 3.5.1.98)(HD7B)(HD7)(Histone deacetylase-related protein)(MEF2-interacting transcription repressor MITR) [Source:UniProtKB/Swiss-Prot;Acc:Q9UKV0] 923 1 QQQQQIQKQ 9 77.7777777777778 5 0.555555555555556 54 62 5 LDLRTDLRMMMPVVDPVVREKQLQQELLLI LLIAEFQKQHENLTRQHQAQLQEHIKELLA GO:0004407:histone deacetylase activity;GO:0005515:protein binding;GO:0003714:transcription corepressor activity; GO:0016568:chromatin modification;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0007507:heart development; GO:0000118:histone deacetylase complex; --- >prot|ENSP00000353871|cod|ENST00000360655|gene|ENSG00000166833|ann|Neuron navigator 2 (EC 3.6.1.-)(Helicase APC down-regulated 1)(Retinoic acid inducible in neuroblastoma 1)(Steerin-2)(Pore membrane and/or filament-interacting-like protein 2)(Unc-53 homolog 2)(unc53H2) [Source:UniProtKB/Swiss-Prot;Acc:Q8IVL1] 2404 1 QQQQQPQKQ 9 77.7777777777778 5 0.555555555555556 108 116 4 INIQGLSAEEIRNGNLKAILGLFFSLSRYK HLSSPLPPAVSQVAGAPSQCQAGTPQQQVP GO:0005525:GTP binding;GO:0000166:nucleotide binding;GO:0017111:nucleoside-triphosphatase activity; GO:0007264:small GTPase mediated signal transduction;GO:0015031:protein transport; --- --- >prot|ENSP00000264731|cod|ENST00000264731|gene|ENSG00000073282|ann|Tumor protein 63 (p63)(Transformation-related protein 63)(TP63)(Tumor protein p73-like)(p73L)(p51)(p40)(Keratinocyte transcription factor KET)(Chronic ulcerative stomatitis protein)(CUSP) [Source:UniProtKB/Swiss-Prot;Acc:Q9H3D4] 680 1 QQQQQQHQ 8 87.5 6 0.75 437 444 64 GRETYEMLLKIKESLELMQYLPQHTIETYR HLLQKQTSIQSPSSYGNSSPPLNKMNSMNK GO:0003677:DNA binding;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0008270:zinc ion binding;GO:0043565:sequence-specific DNA binding;GO:0003684:damaged DNA binding;GO:0003682:chromatin binding; GO:0006355:regulation of transcription, DNA-dependent;GO:0045449:regulation of transcription;GO:0002347:response to tumor cell;GO:0030308:negative regulation of cell growth;GO:0030154:cell differentiation;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0006917:induction of apoptosis;GO:0001501:skeletal system development;GO:0009887:organ morphogenesis;GO:0006916:anti-apoptosis;GO:0002064:epithelial cell development;GO:0030326:embryonic limb morphogenesis;GO:0031069:hair follicle morphogenesis;GO:0030855:epithelial cell differentiation;GO:0001942:hair follicle development;GO:0042475:odontogenesis of dentine-containing tooth;GO:0048745:smooth muscle tissue development;GO:0009954:proximal/distal pattern formation;GO:0051402:neuron apoptosis;GO:0001736:establishment of planar polarity;GO:0002053:positive regulation of mesenchymal cell proliferation;GO:0007389:pattern specification process;GO:0007499:ectoderm and mesoderm interaction;GO:0007569:cell aging;GO:0010259:multicellular organismal aging;GO:0030850:prostate gland development;GO:0030859:polarized epithelial cell differentiation;GO:0035121:tail morphogenesis;GO:0042771:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;GO:0043589:skin morphogenesis;GO:0043616:keratinocyte proliferation;GO:0045617:negative regulation of keratinocyte differentiation;GO:0048485:sympathetic nervous system development;GO:0048646:anatomical structure formation involved in morphogenesis;GO:0048807:female genitalia morphogenesis;GO:0060157:urinary bladder development;GO:0060197:cloacal septation;GO:0008544:epidermis development;GO:0030216:keratinocyte differentiation;GO:0001738:morphogenesis of a polarized epithelium; GO:0005634:nucleus; 605289: SPLIT-HAND/FOOT MALFORMATION 4;604292: ECTRODACTYLY, ECTODERMAL DYSPLASIA, AND CLEFT LIP/PALATE SYNDROME;603543: LIMB-MAMMARY SYNDROME;129400: RAPP-HODGKIN SYNDROME;106260: ANKYLOBLEPHARON-ECTODERMAL DEFECTS-CLEFT LIP/PALATE;103285: ADULT SYNDROME; >prot|ENSP00000171887|cod|ENST00000171887|gene|ENSG00000079308|ann|Tensin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9HBL0] 1735 1 QQQQQQQQQ 9 100 9 1 651 659 37 SFSEAEPQLPPAPVRGGSSREAVQRGLNSW PRPPPRQQERAHLESLVASRPSPQPLAETP GO:0003779:actin binding;GO:0005515:protein binding;GO:0004252:serine-type endopeptidase activity; GO:0006508:proteolysis; GO:0005737:cytoplasm;GO:0005856:cytoskeleton;GO:0030054:cell junction; --- >prot|ENSP00000262719|cod|ENST00000262719|gene|ENSG00000081913|ann|PH domain leucine-rich repeat-containing protein phosphatase (PH domain leucine-rich repeat protein phosphatase)(EC 3.1.3.16)(Pleckstrin homology domain-containing family E protein 1)(Suprachiasmatic nucleus circadian oscillatory protein)(hSCOP)(PHLPP1) [Source:UniProtKB/Swiss-Prot;Acc:O60346] 1717 1 QEQQQQQQ 8 87.5 6 0.75 1682 1689 97 FAAPAQPDPDDQFIIPPELEEEVKEIMKHH PPPPPQLQPQLPRHYQLDQLPDYYDTPL GO:0005515:protein binding;GO:0003824:catalytic activity; --- --- --- >prot|ENSP00000370723|cod|ENST00000381322|gene|ENSG00000134852|ann|Circadian locomoter output cycles protein kaput (hCLOCK)(EC 2.3.1.48) [Source:UniProtKB/Swiss-Prot;Acc:O15516] 846 2 QQQQQQSSQEQQ 12 75 6 0.5 755 766 89 VPSTMLMGQVVTAYPTFATQQQQSQTLSVT LTSVQQPSQAQLTQPPQQFLQTSRLLHGNP GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0004402:histone acetyltransferase activity;GO:0004871:signal transducer activity;GO:0005515:protein binding;GO:0008415:acyltransferase activity;GO:0016740:transferase activity;GO:0030528:transcription regulator activity; GO:0007165:signal transduction;GO:0007623:circadian rhythm;GO:0009648:photoperiodism;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0006355:regulation of transcription, DNA-dependent;GO:0045449:regulation of transcription;GO:0006350:transcription; GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0005667:transcription factor complex; --- >prot|ENSP00000370723|cod|ENST00000381322|gene|ENSG00000134852|ann|Circadian locomoter output cycles protein kaput (hCLOCK)(EC 2.3.1.48) [Source:UniProtKB/Swiss-Prot;Acc:O15516] 846 2 QQHQSQQQQQ 10 80 5 0.5 819 828 96 SRLLHGNPSTQLILSAAFPLQQSTFPQSHH LSRHRTDSLPDPSKVQPQ GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0004402:histone acetyltransferase activity;GO:0004871:signal transducer activity;GO:0005515:protein binding;GO:0008415:acyltransferase activity;GO:0016740:transferase activity;GO:0030528:transcription regulator activity; GO:0007165:signal transduction;GO:0007623:circadian rhythm;GO:0009648:photoperiodism;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0006355:regulation of transcription, DNA-dependent;GO:0045449:regulation of transcription;GO:0006350:transcription; GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0005667:transcription factor complex; --- >prot|ENSP00000362124|cod|ENST00000373033|gene|ENSG00000112561|ann|Transcription factor EB [Source:UniProtKB/Swiss-Prot;Acc:P19484] 476 1 QQQQQQQQQQ 10 100 10 1 35 44 7 IGLRMQLMREQAQQEEQRERMQQQAVMHYM LGGPPTPAINTPVHFQSPPPVPGEVLKVQS GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0030528:transcription regulator activity; GO:0045893:positive regulation of transcription, DNA-dependent;GO:0045449:regulation of transcription; GO:0005634:nucleus;GO:0005667:transcription factor complex; --- >prot|ENSP00000356716|cod|ENST00000367742|gene|ENSG00000117523|ann|BAT2 domain-containing protein 1 (HBxAg transactivated protein 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y520] 2819 1 QQQWQQQQQQ 10 90 6 0.6 686 695 24 QPRPAVLSGYFKQFQKSLPPRFQRQQEQMK GVLPQTVPSQPSSSTVPPPPHRPLYQPMQP --- --- --- --- >prot|ENSP00000319149|cod|ENST00000323199|gene|ENSG00000157212|ann|PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein) [Source:UniProtKB/Swiss-Prot;Acc:Q6ZW49] 1035 5 QQQQQAQQQQQQ 12 91.6666666666667 6 0.5 368 379 35 QQVNHSQQGHTNANAVLFSQVKVTPETHML HPVLHLQPQQIMQLQQQQQQQISQQPYPQQ GO:0045735:nutrient reservoir activity; GO:0031424:keratinization; GO:0005622:intracellular;GO:0005737:cytoplasm; 104300: ALZHEIMER DISEASE; >prot|ENSP00000319149|cod|ENST00000323199|gene|ENSG00000157212|ann|PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein) [Source:UniProtKB/Swiss-Prot;Acc:Q6ZW49] 1035 5 QLQQQQQQQISQQ 13 76.9230769230769 7 0.538461538461538 392 404 37 PETHMLQQQQQAQQQQQQHPVLHLQPQQIM PYPQQPPHPFSQQQQQQQQAHPHQFSQQQL GO:0045735:nutrient reservoir activity; GO:0031424:keratinization; GO:0005622:intracellular;GO:0005737:cytoplasm; 104300: ALZHEIMER DISEASE; >prot|ENSP00000319149|cod|ENST00000323199|gene|ENSG00000157212|ann|PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein) [Source:UniProtKB/Swiss-Prot;Acc:Q6ZW49] 1035 5 QQQQQQQQ 8 100 8 1 416 423 40 QPQQIMQLQQQQQQQISQQPYPQQPPHPFS AHPHQFSQQQLQFPQQQLHPPQQLHRPQQQ GO:0045735:nutrient reservoir activity; GO:0031424:keratinization; GO:0005622:intracellular;GO:0005737:cytoplasm; 104300: ALZHEIMER DISEASE; >prot|ENSP00000319149|cod|ENST00000323199|gene|ENSG00000157212|ann|PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein) [Source:UniProtKB/Swiss-Prot;Acc:Q6ZW49] 1035 5 QQQQQQQIQQQQLQRMHQQQQQQQMQSQ 28 75 7 0.25 491 518 47 HALQQQFHQLQQHQLQQQQLAQLQQQHSLL TAPHLSQTSQALQHQVPPQQPPQQQQQQQP GO:0045735:nutrient reservoir activity; GO:0031424:keratinization; GO:0005622:intracellular;GO:0005737:cytoplasm; 104300: ALZHEIMER DISEASE; >prot|ENSP00000319149|cod|ENST00000323199|gene|ENSG00000157212|ann|PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein) [Source:UniProtKB/Swiss-Prot;Acc:Q6ZW49] 1035 5 QQPPQQQQQQQ 11 81.8181818181818 7 0.636363636363636 537 547 51 HQQQQQQQMQSQTAPHLSQTSQALQHQVPP PPPSPQQHQLFGHDPAVEIPEEGFLLGCVF GO:0045735:nutrient reservoir activity; GO:0031424:keratinization; GO:0005622:intracellular;GO:0005737:cytoplasm; 104300: ALZHEIMER DISEASE; >prot|ENSP00000382703|cod|ENST00000399804|gene|ENSG00000156304|ann|Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4) [Source:UniProtKB/Swiss-Prot;Acc:O95104] 1125 1 QQPQQQQQQQ 10 90 7 0.7 935 944 83 PGPGPGGPEDRDGRQQPPQQPQQQPQPQAP PPPSQQPPPTQQQPQQFRNDNRQQFNSGRD GO:0000166:nucleotide binding;GO:0003723:RNA binding;GO:0003676:nucleic acid binding;GO:0005199:structural constituent of cell wall;GO:0008022:protein C-terminus binding; GO:0006397:mRNA processing; GO:0005634:nucleus; --- >prot|ENSP00000385211|cod|ENST00000407032|gene|ENSG00000104805|ann|Nucleobindin-1 Precursor (CALNUC) [Source:UniProtKB/Swiss-Prot;Acc:Q02818] 461 1 QRKQQQQQQQ 10 80 7 0.7 398 407 86 LSQETEALGRSQGRLEAQKRELQQAVLHME GHKAPAAHPEGQLKFHPDTDDVPVPAPAGD GO:0003677:DNA binding;GO:0005509:calcium ion binding; --- GO:0016020:membrane;GO:0005615:extracellular space;GO:0005737:cytoplasm;GO:0005793:ER-Golgi intermediate compartment;GO:0005794:Golgi apparatus;GO:0005856:cytoskeleton; --- >prot|ENSP00000219905|cod|ENST00000219905|gene|ENSG00000174197|ann|MAX gene-associated protein [Source:UniProtKB/Swiss-Prot;Acc:Q8IWI9] 3114 1 QAQQQQQQQQ 10 90 8 0.8 972 981 31 SSGIISENQANNFVVPTLDENIFPKQISLR GSRPPGLSKSQVKLMDLEDCALWEGKPRTY GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0030528:transcription regulator activity; GO:0006355:regulation of transcription, DNA-dependent;GO:0045449:regulation of transcription; GO:0005634:nucleus; --- >prot|ENSP00000354764|cod|ENST00000361147|gene|ENSG00000143603|ann|Small conductance calcium-activated potassium channel protein 3 (SKCa3)(SK3) [Source:UniProtKB/Swiss-Prot;Acc:Q9UGI6] 426 1 QQQQQ 5 100 5 1 378 382 88 EKQIGSLESKLEHLTASFNSLPLLIADTLR LLSAIIEARGVSVAVGTTHTPISDSPIGVS GO:0005249:voltage-gated potassium channel activity;GO:0005516:calmodulin binding;GO:0015269:calcium-activated potassium channel activity; GO:0006813:potassium ion transport; GO:0016021:integral to membrane;GO:0008076:voltage-gated potassium channel complex; --- >prot|ENSP00000259523|cod|ENST00000259523|gene|ENSG00000136997|ann|Myc proto-oncogene protein (c-Myc)(Transcription factor p64) [Source:UniProtKB/Swiss-Prot;Acc:P01106] 257 1 QQQQQ 5 100 5 1 33 37 12 LNVSFTNRNYDLDYDSVQPYFYCDEEENFY SELQPPAPSEDIWKKFELLPTPPLSPSRRS GO:0003690:double-stranded DNA binding;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0005515:protein binding;GO:0043565:sequence-specific DNA binding;GO:0030528:transcription regulator activity;GO:0003677:DNA binding; GO:0001783:B cell apoptosis;GO:0001836:release of cytochrome c from mitochondria;GO:0006006:glucose metabolic process;GO:0006309:DNA fragmentation involved in apoptotic nuclear change;GO:0006352:transcription initiation;GO:0006879:cellular iron ion homeostasis;GO:0006919:activation of caspase activity;GO:0007050:cell cycle arrest;GO:0007346:regulation of mitotic cell cycle;GO:0008284:positive regulation of cell proliferation;GO:0008629:induction of apoptosis by intracellular signals;GO:0008633:activation of pro-apoptotic gene products;GO:0008634:negative regulation of survival gene product expression;GO:0009314:response to radiation;GO:0016485:protein processing;GO:0032204:regulation of telomere maintenance;GO:0042474:middle ear morphogenesis;GO:0042981:regulation of apoptosis;GO:0043085:positive regulation of catalytic activity;GO:0043279:response to alkaloid;GO:0043473:pigmentation;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0048705:skeletal system morphogenesis;GO:0050910:detection of mechanical stimulus involved in sensory perception of sound;GO:0045449:regulation of transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0010468:regulation of gene expression;GO:0002904:positive regulation of B cell apoptosis;GO:0006366:transcription from RNA polymerase II promoter; GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0005819:spindle;GO:0016604:nuclear body; 113970: BURKITT LYMPHOMA; >prot|ENSP00000262069|cod|ENST00000262069|gene|ENSG00000048052|ann|Histone deacetylase 9 (HD9)(EC 3.5.1.98)(HD7B)(HD7)(Histone deacetylase-related protein)(MEF2-interacting transcription repressor MITR) [Source:UniProtKB/Swiss-Prot;Acc:Q9UKV0] 1069 1 QQQQQIQKQ 9 77.7777777777778 5 0.555555555555556 54 62 5 LDLRTDLRMMMPVVDPVVREKQLQQELLLI LLIAEFQKQHENLTRQHQAQLQEHIKLQQE GO:0004407:histone deacetylase activity;GO:0005515:protein binding;GO:0003714:transcription corepressor activity; GO:0016568:chromatin modification;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0007507:heart development; GO:0000118:histone deacetylase complex; --- >prot|ENSP00000355568|cod|ENST00000366609|gene|ENSG00000168264|ann|Interferon regulatory factor 2-binding protein 2 (IRF-2-binding protein 2)(IRF-2BP2) [Source:UniProtKB/Swiss-Prot;Acc:Q7Z5L9] 587 1 QQQQQ 5 100 5 1 94 98 16 GCFPEGRSPPGAAASAAAKPPPLSAKDILL LGHGGPEAAPRAPQALERYPLAAAAERPPR GO:0003677:DNA binding;GO:0004879:ligand-dependent nuclear receptor activity; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent; GO:0005634:nucleus; --- >prot|ENSP00000267064|cod|ENST00000267064|gene|ENSG00000139613|ann|SWI/SNF complex subunit SMARCC2 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)(SWI/SNF complex 170 kDa subunit)(BRG1-associated factor 170) [Source:UniProtKB/Swiss-Prot;Acc:Q8TAQ2] 1214 1 QQQQQ 5 100 5 1 956 960 78 QLLADRQAFHMEQLKYAEMRARQQHFQQMH PPPALPPGSQPIPPTGAAGPPAVHGLAVAP GO:0003682:chromatin binding;GO:0003677:DNA binding; GO:0006333:chromatin assembly or disassembly; GO:0005622:intracellular;GO:0000785:chromatin;GO:0005634:nucleus; --- >prot|ENSP00000361569|cod|ENST00000372491|gene|ENSG00000188483|ann|Immediate early response gene 5-like protein [Source:UniProtKB/Swiss-Prot;Acc:Q5T953] 404 1 QQQQQQQQ 8 100 8 1 59 66 14 KLHKNLLVSYVLRNARQLYLSERYAELYRR PPHHQHQHLAYAAPGMPASAADFGPLQLGG GO:0005199:structural constituent of cell wall; --- --- --- >prot|ENSP00000381556|cod|ENST00000398548|gene|ENSG00000141956|ann|PR domain zinc finger protein 15 (PR domain-containing protein 15)(Zinc finger protein 298) [Source:UniProtKB/Swiss-Prot;Acc:P57071] 1178 1 QQQQQ 5 100 5 1 1170 1174 99 WRAVPQTDVLPPSQPQAPPQQAAQPQVQAE MYSY GO:0003677:DNA binding;GO:0008270:zinc ion binding;GO:0046872:metal ion binding;GO:0003676:nucleic acid binding;GO:0005525:GTP binding; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0007017:microtubule-based process; GO:0005622:intracellular;GO:0005634:nucleus;GO:0005874:microtubule; --- >prot|ENSP00000382767|cod|ENST00000399878|gene|ENSG00000091490|ann|SEL1-like repeat-containing protein KIAA0746 [Source:UniProtKB/Swiss-Prot;Acc:Q68CR1] 1132 1 QQQQQ 5 100 5 1 13 17 1 MQRRGAGLGWPRQQQQQPPPLAVGPRAAAM PPPLAVGPRAAAMVPSGGVPQGLGGRSACA GO:0005488:binding; --- GO:0016020:membrane;GO:0016021:integral to membrane; --- >prot|ENSP00000310301|cod|ENST00000310015|gene|ENSG00000172845|ann|Transcription factor Sp3 (SPR-2) [Source:UniProtKB/Swiss-Prot;Acc:Q02447] 781 1 QQQQQ 5 100 5 1 35 39 4 EKPVKQEEMAALDVDSGGGGGGGGGHGEYL HGNGAVAAAAAAQDTQPSPLALLAATCSKI GO:0003677:DNA binding;GO:0003682:chromatin binding;GO:0003690:double-stranded DNA binding;GO:0005515:protein binding;GO:0008270:zinc ion binding;GO:0016563:transcription activator activity;GO:0016564:transcription repressor activity;GO:0046872:metal ion binding;GO:0050825:ice binding; GO:0001503:ossification;GO:0001779:natural killer cell differentiation;GO:0001829:trophectodermal cell differentiation;GO:0001889:liver development;GO:0001892:embryonic placenta development;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0030183:B cell differentiation;GO:0030217:T cell differentiation;GO:0030219:megakaryocyte differentiation;GO:0030224:monocyte differentiation;GO:0030324:lung development;GO:0030851:granulocyte differentiation;GO:0043353:enucleate erythrocyte differentiation;GO:0048596:embryonic camera-type eye morphogenesis;GO:0048706:embryonic skeletal system development;GO:0060136:embryonic process involved in female pregnancy;GO:0060216:definitive hemopoiesis;GO:0042309:homoiothermy;GO:0050826:response to freezing; GO:0005622:intracellular;GO:0005634:nucleus; --- >prot|ENSP00000222270|cod|ENST00000222270|gene|ENSG00000105663|ann|Histone-lysine N-methyltransferase MLL4 (EC 2.1.1.43)(Myeloid/lymphoid or mixed-lineage leukemia protein 4)(WW domain-binding protein 7)(WBP-7)(Trithorax homolog 2)(Lysine N-methyltransferase 2D) [Source:UniProtKB/Swiss-Prot;Acc:Q9UMN6] 2715 1 QQQQQ 5 100 5 1 808 812 29 AGVGSLPLSGVEEKMFSLLKRAKVQLFKID KVAASMPLSPGGQMEEVAGAVKQISDRGPV GO:0005249:voltage-gated potassium channel activity;GO:0003677:DNA binding;GO:0005198:structural molecule activity; GO:0006813:potassium ion transport;GO:0007186:G-protein coupled receptor protein signaling pathway;GO:0007155:cell adhesion; GO:0016021:integral to membrane;GO:0015629:actin cytoskeleton; --- >prot|ENSP00000381590|cod|ENST00000398590|gene|ENSG00000163635|ann|Ataxin-7 (Spinocerebellar ataxia type 7 protein) [Source:UniProtKB/Swiss-Prot;Acc:O15265] 945 1 QQQQQQQQQQ 10 100 10 1 30 39 3 MSERAADDVRGEPRRAAAAAGGAAAAAARQ PPPPQPQRQQHPPPPPRRTRPEDGGPGAAS GO:0005515:protein binding;GO:0008270:zinc ion binding; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0006997:nucleus organization;GO:0007601:visual perception;GO:0008219:cell death; GO:0005622:intracellular;GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0016363:nuclear matrix; 164500: SPINOCEREBELLAR ATAXIA 7; >prot|ENSP00000341024|cod|ENST00000338745|gene|ENSG00000182568|ann|DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1) [Source:UniProtKB/Swiss-Prot;Acc:Q01826] 763 1 QIQQQQQQQQQQQQQQQ 17 94.1176470588235 15 0.882352941176471 591 607 77 PERDAIYEQESNAVHHHGDRPPHIIHVPAE APPPPQPQQQPQTGPRLPPRQPTVASPAES GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0043565:sequence-specific DNA binding;GO:0003677:DNA binding;GO:0016564:transcription repressor activity; GO:0006355:regulation of transcription, DNA-dependent;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0016571:histone methylation;GO:0042110:T cell activation;GO:0006325:chromatin organization;GO:0050798:activated T cell proliferation;GO:0043367:CD4-positive, alpha beta T cell differentiation;GO:0043374:CD8-positive, alpha-beta T cell differentiation;GO:0060004:reflex; GO:0000785:chromatin;GO:0005634:nucleus;GO:0005720:nuclear heterochromatin;GO:0016363:nuclear matrix; --- >prot|ENSP00000364324|cod|ENST00000375180|gene|ENSG00000184083|ann|Constitutive coactivator of PPAR-gamma-like protein 2 (Protein FAM120C)(Tumor antigen BJ-HCC-21) [Source:UniProtKB/Swiss-Prot;Acc:Q9NX05] 1096 1 QQQQQ 5 100 5 1 33 37 3 VQGFQEFLEKRCPGAVVPVDLLKLARTVSR HLHRQLPPTAALAPGAPRAARGSVPLQPPL --- --- --- --- >prot|ENSP00000380358|cod|ENST00000397173|gene|ENSG00000151065|ann|mRNA-decapping enzyme 1B (EC 3.-.-.-) [Source:UniProtKB/Swiss-Prot;Acc:Q8IZD4] 519 1 QTLHQQQQQQQQQQ 14 78.5714285714286 10 0.714285714285714 150 163 28 TLDPEPQHLSLTALFGKQDKATCQETVEPP EKLPIRQGVVRSLSYEEPRRHSPPIEKQLC GO:0005515:protein binding;GO:0016787:hydrolase activity; GO:0000184:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0005634:nucleus;GO:0005737:cytoplasm; --- >prot|ENSP00000219746|cod|ENST00000219746|gene|ENSG00000103460|ann|TOX high mobility group box family member 3 (Trinucleotide repeat-containing gene 9 protein)(CAG trinucleotide repeat-containing gene F9 protein) [Source:UniProtKB/Swiss-Prot;Acc:O15405] 576 2 QTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQ 32 75 10 0.3125 437 468 75 MPSNIGAPLISSMGTTMVGSAPSTQVSPSV MHQQIQQQMQQQHFQHHMQQHLQQQQQHLQ GO:0003677:DNA binding; --- GO:0005634:nucleus; --- >prot|ENSP00000219746|cod|ENST00000219746|gene|ENSG00000103460|ann|TOX high mobility group box family member 3 (Trinucleotide repeat-containing gene 9 protein)(CAG trinucleotide repeat-containing gene F9 protein) [Source:UniProtKB/Swiss-Prot;Acc:O15405] 576 2 QQHLQQQQQ 9 77.7777777777778 5 0.555555555555556 487 495 84 QQMQQQQLQQHQMHQQIQQQMQQQHFQHHM HLQQQINQQQLQQQLQQRLQLQQLQHMQHQ GO:0003677:DNA binding; --- GO:0005634:nucleus; --- >prot|ENSP00000337602|cod|ENST00000348405|gene|ENSG00000138674|ann|Protein transport protein Sec31A (SEC31-related protein A)(SEC31-like 1)(ABP125)(ABP130)(Web1-like protein) [Source:UniProtKB/Swiss-Prot;Acc:O94979] 1181 1 QQQQQ 5 100 5 1 420 424 35 IRRPVGASFSFGGKLVTFENVRMPSHQGAE HHVFISQVVTEKEFLSRSDQLQQAVQSQGF GO:0048306:calcium-dependent protein binding;GO:0045735:nutrient reservoir activity; GO:0006888:ER to Golgi vesicle-mediated transport;GO:0015031:protein transport;GO:0016044:cellular membrane organization;GO:0016192:vesicle-mediated transport;GO:0051592:response to calcium ion; GO:0016020:membrane;GO:0005783:endoplasmic reticulum;GO:0005737:cytoplasm;GO:0005789:endoplasmic reticulum membrane;GO:0030127:COPII vesicle coat;GO:0031410:cytoplasmic vesicle;GO:0048471:perinuclear region of cytoplasm; --- >prot|ENSP00000268711|cod|ENST00000268711|gene|ENSG00000141026|ann|Mediator of RNA polymerase II transcription subunit 9 (Mediator complex subunit 9) [Source:UniProtKB/Swiss-Prot;Acc:Q9NWA0] 146 1 QQQQQLQ 7 85.7142857142857 5 0.714285714285714 113 119 77 VHQDLNALKSKFQEMRKLISTMPGIHLSPE SLREQVRTKNELLQKYKSLCMFEIPKE GO:0005515:protein binding;GO:0045735:nutrient reservoir activity; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent; GO:0000119---GO:0005634:nucleus; --- >prot|ENSP00000359039|cod|ENST00000370022|gene|ENSG00000134186|ann|Pre-mRNA-splicing factor 38B (Sarcoma antigen NY-SAR-27) [Source:UniProtKB/Swiss-Prot;Acc:Q5VTL8] 190 1 QQQQQ 5 100 5 1 24 28 12 MANNSPALTGNSQPQHQAAAAAAQQQQQCG CGGGGATKPAVSGKQGNVLPLWGNEKTMNL GO:0005245:voltage-gated calcium channel activity; GO:0006816:calcium ion transport; GO:0016021:integral to membrane; --- >prot|ENSP00000344380|cod|ENST00000338949|gene|ENSG00000122483|ann|Coiled-coil domain-containing protein 18 (Sarcoma antigen NY-SAR-24) [Source:UniProtKB/Swiss-Prot;Acc:Q5T9S5] 803 1 QQQQQMLQQ 9 77.7777777777778 5 0.555555555555556 549 557 68 EVYCLQKELKIKNHSLQETSEQNVILQHTL ETIRNGELEDTQTKLEKQVSKLEQELQKQR GO:0000166:nucleotide binding;GO:0003677:DNA binding; --- --- --- >prot|ENSP00000309893|cod|ENST00000309027|gene|ENSG00000173905|ann|Golgi integral membrane protein 4 (Golgi phosphoprotein 4)(Golgi integral membrane protein, cis)(GIMPc)(Golgi-localized phosphoprotein of 130 kDa)(Golgi phosphoprotein of 130 kDa) [Source:UniProtKB/Swiss-Prot;Acc:O00461] 668 1 QQEQQQQQ 8 87.5 5 0.625 418 425 62 LAVQQVEEAQQLREHQEALHQQRLQGHLLR VAREMALQRQAELEEGRPQHQEQLRQQAHY --- GO:0006810:transport; GO:0016020:membrane;GO:0016021:integral to membrane;GO:0005634:nucleus;GO:0005768:endosome;GO:0005794:Golgi apparatus;GO:0005796:Golgi lumen;GO:0005801:cis-Golgi network;GO:0030139:endocytic vesicle;GO:0010008:endosome membrane; --- >prot|ENSP00000384202|cod|ENST00000404621|gene|ENSG00000196498|ann|Nuclear receptor corepressor 2 (N-CoR2)(Silencing mediator of retinoic acid and thyroid hormone receptor)(SMRTe)(SMRT)(Thyroid-, retinoic-acid-receptor-associated corepressor)(T3 receptor-associating factor)(TRAC)(CTG repeat protein 26)(SMAP270) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y618] 2458 1 QQQQQQQQQQQQQQQQQ 17 100 17 1 493 509 20 AECVLYYYLTKKNENYKSLVRRSYRRRGKS PMPRSSQEEKDEKEKEKEAEKEEEKPEVEN GO:0003677:DNA binding; --- --- --- >prot|ENSP00000295470|cod|ENST00000295470|gene|ENSG00000152795|ann|Heterogeneous nuclear ribonucleoprotein D-like (hnRPD-like protein)(hnHNRP-DL)(JKT41-binding protein)(AU-rich element RNA-binding factor)(Protein laAUF1) [Source:UniProtKB/Swiss-Prot;Acc:O14979] 420 1 QQQQQQ 6 100 6 1 316 321 75 PVKKLLESRYHQIGSGKCEIKVAQPKEVYR KGGRGAAAGGRGGTRGRGRGQGQNWNQGFN GO:0000166:nucleotide binding;GO:0003677:DNA binding;GO:0003690:double-stranded DNA binding;GO:0003697:single-stranded DNA binding;GO:0003723:RNA binding;GO:0005515:protein binding;GO:0008143:poly(A) RNA binding;GO:0003676:nucleic acid binding; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0006396:RNA processing; GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0030530:heterogeneous nuclear ribonucleoprotein complex; --- >prot|ENSP00000346285|cod|ENST00000354325|gene|ENSG00000124496|ann|Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132)(Zinc finger transcription factor TReP-132)(Zinc finger protein rapa)(Breast cancer anti-estrogen resistance 2) [Source:UniProtKB/Swiss-Prot;Acc:Q96PN7] 1117 2 QQQQQAGQQ 9 77.7777777777778 5 0.555555555555556 273 281 24 VPVQGGQPLQAPQMLSQHMQQMQQHQYYPP RISMQEIQTQPQQIRPSQPQPPPQQQQPQQ GO:0003677:DNA binding;GO:0008270:zinc ion binding; --- GO:0005622:intracellular; --- >prot|ENSP00000346285|cod|ENST00000354325|gene|ENSG00000124496|ann|Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132)(Zinc finger transcription factor TReP-132)(Zinc finger protein rapa)(Breast cancer anti-estrogen resistance 2) [Source:UniProtKB/Swiss-Prot;Acc:Q96PN7] 1117 2 QEQQQQQ 7 85.7142857142857 5 0.714285714285714 337 343 30 QQPQQLQLQQRQGSMQIPQYYQPQPMMQHL MHLQPPSYHRDPHQYTPEQAHTVQLIPLGS GO:0003677:DNA binding;GO:0008270:zinc ion binding; --- GO:0005622:intracellular; --- >prot|ENSP00000362814|cod|ENST00000373710|gene|ENSG00000168528|ann|Serine incorporator 2 (Tumor differentially expressed 2-like) [Source:UniProtKB/Swiss-Prot;Acc:Q96SA4] 464 1 QQQQQ 5 100 5 1 373 377 80 TLFISLRSSDHRQVNSLMQTEECPPMLDAT VAACEGRAFDNEQDGVTYSYSFFHFCLVLA --- --- GO:0016020:membrane;GO:0016021:integral to membrane; --- >prot|ENSP00000323550|cod|ENST00000323508|gene|ENSG00000005339|ann|CREB-binding protein (EC 2.3.1.48) [Source:UniProtKB/Swiss-Prot;Acc:Q92793] 977 2 QQQQQ 5 100 5 1 616 620 63 PRMPSVQPPRSISPSALQDLLRTLKSPSSP VLNILKSNPQLMAAFIKQRTAKYVANQPGM GO:0003712:transcription cofactor activity;GO:0004402:histone acetyltransferase activity;GO:0008270:zinc ion binding;GO:0005515:protein binding;GO:0003713:transcription coactivator activity;GO:0005524:ATP binding;GO:0016887:ATPase activity;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0042975:peroxisome proliferator activated receptor binding;GO:0046332:SMAD binding;GO:0003677:DNA binding; GO:0006355:regulation of transcription, DNA-dependent;GO:0045449:regulation of transcription;GO:0016573:histone acetylation;GO:0008283:cell proliferation;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0045893:positive regulation of transcription, DNA-dependent;GO:0045941:positive regulation of transcription;GO:0030718:germ-line stem cell maintenance; GO:0000123:histone acetyltransferase complex;GO:0000940:condensed chromosome outer kinetochore;GO:0005634:nucleus;GO:0005667:transcription factor complex; 180849: RUBINSTEIN-TAYBI SYNDROME; >prot|ENSP00000323550|cod|ENST00000323508|gene|ENSG00000005339|ann|CREB-binding protein (EC 2.3.1.48) [Source:UniProtKB/Swiss-Prot;Acc:Q92793] 977 2 QLLQQQQQQQQQQQQQQQQQQ 21 90.4761904761905 18 0.857142857142857 731 751 74 PQGQALNIMNPGHNPNMASMNPQYREMLRR GSAGMAGGMAGHGQFQQPQGPGGYPPAMQQ GO:0003712:transcription cofactor activity;GO:0004402:histone acetyltransferase activity;GO:0008270:zinc ion binding;GO:0005515:protein binding;GO:0003713:transcription coactivator activity;GO:0005524:ATP binding;GO:0016887:ATPase activity;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0042975:peroxisome proliferator activated receptor binding;GO:0046332:SMAD binding;GO:0003677:DNA binding; GO:0006355:regulation of transcription, DNA-dependent;GO:0045449:regulation of transcription;GO:0016573:histone acetylation;GO:0008283:cell proliferation;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0045893:positive regulation of transcription, DNA-dependent;GO:0045941:positive regulation of transcription;GO:0030718:germ-line stem cell maintenance; GO:0000123:histone acetyltransferase complex;GO:0000940:condensed chromosome outer kinetochore;GO:0005634:nucleus;GO:0005667:transcription factor complex; 180849: RUBINSTEIN-TAYBI SYNDROME; >prot|ENSP00000387170|cod|ENST00000409451|gene|ENSG00000204120|ann|PERQ amino acid-rich with GYF domain-containing protein 2 (GRB10-interacting GYF protein 2)(Trinucleotide repeat-containing gene 15 protein) [Source:UniProtKB/Swiss-Prot;Acc:Q6Y7W6] 1320 5 QQQQQ 5 100 5 1 672 676 50 QMQHLQYQQFLIQQQYAQVLAQQQKAALSS LALLLQQFQTLKMRISDQNIIPSVTRSVSV GO:0005515:protein binding; --- --- 607688: PARKINSON DISEASE 11; >prot|ENSP00000387170|cod|ENST00000409451|gene|ENSG00000204120|ann|PERQ amino acid-rich with GYF domain-containing protein 2 (GRB10-interacting GYF protein 2)(Trinucleotide repeat-containing gene 15 protein) [Source:UniProtKB/Swiss-Prot;Acc:Q6Y7W6] 1320 5 QQQQQQQQLAQ 11 81.8181818181818 8 0.727272727272727 931 941 70 EERKRKELEVQRQKELMRQRQQQQEALRRL MKLPSSSTWGQQSNTTACQSQATLSLAEIQ GO:0005515:protein binding; --- --- 607688: PARKINSON DISEASE 11; >prot|ENSP00000387170|cod|ENST00000409451|gene|ENSG00000204120|ann|PERQ amino acid-rich with GYF domain-containing protein 2 (GRB10-interacting GYF protein 2)(Trinucleotide repeat-containing gene 15 protein) [Source:UniProtKB/Swiss-Prot;Acc:Q6Y7W6] 1320 5 QQQQQQQQQ 9 100 9 1 997 1005 75 LAEIQKLEEERERQLREEQRRQQRELMKAL KLSGWGNVSKPSGTTKSLLEIQQEEARQMQ GO:0005515:protein binding; --- --- 607688: PARKINSON DISEASE 11; >prot|ENSP00000387170|cod|ENST00000409451|gene|ENSG00000204120|ann|PERQ amino acid-rich with GYF domain-containing protein 2 (GRB10-interacting GYF protein 2)(Trinucleotide repeat-containing gene 15 protein) [Source:UniProtKB/Swiss-Prot;Acc:Q6Y7W6] 1320 5 QMQKQQQQQQQHQQ 14 78.5714285714286 7 0.5 1033 1046 78 QQQKLSGWGNVSKPSGTTKSLLEIQQEEAR PNRARNNTHSNLHTSIGNSVWGSINTGPPN GO:0005515:protein binding; --- --- 607688: PARKINSON DISEASE 11; >prot|ENSP00000387170|cod|ENST00000409451|gene|ENSG00000204120|ann|PERQ amino acid-rich with GYF domain-containing protein 2 (GRB10-interacting GYF protein 2)(Trinucleotide repeat-containing gene 15 protein) [Source:UniProtKB/Swiss-Prot;Acc:Q6Y7W6] 1320 5 QQRQQQQLPQQQQQQ 15 80 6 0.4 1223 1237 92 DYIRAYLGDTSEAKEFAKQFLERRAKQKAN PPQQPPQQPQQQDSVWGMNHSTLHSVFQTN GO:0005515:protein binding; --- --- 607688: PARKINSON DISEASE 11; >prot|ENSP00000268957|cod|ENST00000268957|gene|ENSG00000141232|ann|Protein Tob1 (Transducer of erbB-2 1) [Source:UniProtKB/Swiss-Prot;Acc:P50616] 345 2 QQQPQQQQQPAQ 12 75 5 0.416666666666667 237 248 68 INLGLNVNDLLKQKAISSSMHSLYGLGLGS PPPPPPPPQQQQQQKTSALSPNAKEFIFPN GO:0003714:transcription corepressor activity;GO:0005070:SH3/SH2 adaptor activity;GO:0046332:SMAD binding;GO:0005515:protein binding; GO:0007184:SMAD protein nuclear translocation;GO:0008285:negative regulation of cell proliferation;GO:0030514:negative regulation of BMP signaling pathway;GO:0045668:negative regulation of osteoblast differentiation; GO:0005737:cytoplasm; --- >prot|ENSP00000268957|cod|ENST00000268957|gene|ENSG00000141232|ann|Protein Tob1 (Transducer of erbB-2 1) [Source:UniProtKB/Swiss-Prot;Acc:P50616] 345 2 QQQQQQ 6 100 6 1 257 262 74 HSLYGLGLGSQQQPQQQQQPAQPPPPPPPP KTSALSPNAKEFIFPNMQGQGSSTNGMFPG GO:0003714:transcription corepressor activity;GO:0005070:SH3/SH2 adaptor activity;GO:0046332:SMAD binding;GO:0005515:protein binding; GO:0007184:SMAD protein nuclear translocation;GO:0008285:negative regulation of cell proliferation;GO:0030514:negative regulation of BMP signaling pathway;GO:0045668:negative regulation of osteoblast differentiation; GO:0005737:cytoplasm; --- >prot|ENSP00000351784|cod|ENST00000358907|gene|ENSG00000179912|ann|R3H domain-containing protein 2 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y2K5] 976 1 QQQQQQQQQQ 10 100 10 1 404 413 41 SRPGMALGAPEVCNQVTSSQSVRGLLPCTA LPALPPTPQQQPPLNNHMISQADDLSNPFG GO:0003676:nucleic acid binding;GO:0045735:nutrient reservoir activity; --- --- --- >prot|ENSP00000371977|cod|ENST00000382537|gene|ENSG00000179361|ann|AT-rich interactive domain-containing protein 3A (ARID domain-containing protein 3A)(Dead ringer-like protein 1)(B-cell regulator of IgH transcription)(Bright)(E2F-binding protein 1) [Source:UniProtKB/Swiss-Prot;Acc:Q99856] 435 1 QQQQQQQQQQQKQ 13 92.3076923076923 11 0.846153846153846 5 17 1 MEPLQQQQQQQQQQQKQPHLAPLQMDAREK PHLAPLQMDAREKQGQQMREAQFLYAQKLV GO:0003677:DNA binding; --- GO:0005622:intracellular; --- >prot|ENSP00000369476|cod|ENST00000380133|gene|ENSG00000139597|ann|NEDD4-binding protein 2-like 1 [Source:UniProtKB/Swiss-Prot;Acc:Q5TBK1] 243 1 QPQQQQQRQ 9 77.7777777777778 5 0.555555555555556 15 23 6 MEDSFLQSFGRLSLQPQQQQQRQRPPRPPP RPPRPPPRGTPPRRHSFRKHLYLLRGLPGS GO:0000166:nucleotide binding;GO:0017111:nucleoside-triphosphatase activity; --- --- --- >prot|ENSP00000361073|cod|ENST00000372004|gene|ENSG00000124151|ann|Nuclear receptor coactivator 3 (NCoA-3)(EC 2.3.1.48)(Thyroid hormone receptor activator molecule 1)(TRAM-1)(ACTR)(Receptor-associated coactivator 3)(RAC-3)(Amplified in breast cancer-1 protein)(AIB-1)(Steroid receptor coactivator protein 3)(SRC-3)(CBP-interacting protein)(pCIP) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y6Q9] 1420 2 QQQQQMLQ 8 75 5 0.625 976 983 68 NTSLPRPALGGSIPTLPLRSNSIPGARPVL MRPGEIPMGMGANPYGQAAASNQLGSWPDG GO:0004871:signal transducer activity;GO:0030528:transcription regulator activity;GO:0003713:transcription coactivator activity;GO:0035257:nuclear hormone receptor binding; GO:0007165:signal transduction;GO:0045449:regulation of transcription;GO:0006355:regulation of transcription, DNA-dependent; GO:0005634:nucleus; --- >prot|ENSP00000361073|cod|ENST00000372004|gene|ENSG00000124151|ann|Nuclear receptor coactivator 3 (NCoA-3)(EC 2.3.1.48)(Thyroid hormone receptor activator molecule 1)(TRAM-1)(ACTR)(Receptor-associated coactivator 3)(RAC-3)(Amplified in breast cancer-1 protein)(AIB-1)(Steroid receptor coactivator protein 3)(SRC-3)(CBP-interacting protein)(pCIP) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y6Q9] 1420 2 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQ 31 96.7741935483871 29 0.935483870967742 1244 1274 87 QGFLNAQMVAQRSRELLSHHFRQQRVAMMM AFSPPPNVTASPSMDGLLAGPTMPQAPPQQ GO:0004871:signal transducer activity;GO:0030528:transcription regulator activity;GO:0003713:transcription coactivator activity;GO:0035257:nuclear hormone receptor binding; GO:0007165:signal transduction;GO:0045449:regulation of transcription;GO:0006355:regulation of transcription, DNA-dependent; GO:0005634:nucleus; --- >prot|ENSP00000352514|cod|ENST00000359524|gene|ENSG00000124813|ann|Runt-related transcription factor 2 (Core-binding factor subunit alpha-1)(CBF-alpha-1)(Acute myeloid leukemia 3 protein)(Oncogene AML-3)(Polyomavirus enhancer-binding protein 2 alpha A subunit)(PEBP2-alpha A)(PEA2-alpha A)(SL3-3 enhancer factor 1 alpha A subunit)(SL3/AKV core-binding factor alpha A subunit)(Osteoblast-specific transcription factor 2)(OSF-2) [Source:UniProtKB/Swiss-Prot;Acc:Q13950] 589 1 QQQQQQQQQQQQQQQQQQQQQQQ 23 100 23 1 117 139 19 WDPSTSRRFSPPSSSLQPGKMSDVSPVVAA EAAAAAAAAAAAAAAAAAVPRLRPPHDNRT GO:0003677:DNA binding;GO:0005524:ATP binding;GO:0050825:ice binding;GO:0003700:sequence-specific DNA binding transcription factor activity; GO:0006355:regulation of transcription, DNA-dependent;GO:0042309:homoiothermy;GO:0050826:response to freezing;GO:0045449:regulation of transcription; GO:0005634:nucleus; 119600: CLEIDOCRANIAL DYSPLASIA; >prot|ENSP00000375084|cod|ENST00000390668|gene|ENSG00000128573|ann|Forkhead box protein P2 (CAG repeat protein 44)(Trinucleotide repeat-containing gene 10 protein) [Source:UniProtKB/Swiss-Prot;Acc:O15409] 456 1 QQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQ 68 80.8823529411765 40 0.588235294117647 166 233 36 VLSPQQLQALLQQQQAVMLQQQQLQEFYKK LAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ GO:0008270:zinc ion binding; --- GO:0005622:intracellular; --- >prot|ENSP00000354370|cod|ENST00000361078|gene|ENSG00000055917|ann|Pumilio homolog 2 (Pumilio-2) [Source:UniProtKB/Swiss-Prot;Acc:Q8TB72] 1066 1 QPPQQQQQQ 9 77.7777777777778 6 0.666666666666667 505 513 47 AAQAAAAAAAGGTASSLTGSTNGLFRPIGT PSTNLQSNSFYGSSSLTNSSQSSSLFSHGP GO:0050825:ice binding;GO:0003723:RNA binding;GO:0005488:binding; GO:0042309:homoiothermy;GO:0050826:response to freezing; --- --- >prot|ENSP00000283152|cod|ENST00000283152|gene|ENSG00000010017|ann|Ran-binding protein 9 (RanBP9)(RanBP7)(Ran-binding protein M)(RanBPM)(BPM90)(BPM-L) [Source:UniProtKB/Swiss-Prot;Acc:Q96S59] 391 1 QQQQQQQQ 8 100 8 1 11 18 2 MSGQPPPPPPQQQQQQQQLSPPPPAALAPV LSPPPPAALAPVSGVVLPAPPAVSAGSSPA GO:0005515:protein binding;GO:0008536:Ran GTPase binding;GO:0005179:hormone activity;GO:0005198:structural molecule activity; GO:0006461:protein complex assembly;GO:0007020:microtubule nucleation;GO:0007155:cell adhesion; GO:0005576:extracellular region;GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0005875:microtubule associated complex;GO:0015629:actin cytoskeleton; --- >prot|ENSP00000344830|cod|ENST00000339693|gene|ENSG00000114861|ann|Forkhead box protein P1 [Source:UniProtKB/Swiss-Prot;Acc:Q9H334] 601 2 QQQQQQALQ 9 77.7777777777778 6 0.666666666666667 55 63 9 HLLECGGLREGRSNGETPAVDIGAADLAHA VARQLLLQQQQQQQVSGLKSPKRNDKQPAL GO:0008270:zinc ion binding; --- GO:0005622:intracellular; --- >prot|ENSP00000344830|cod|ENST00000339693|gene|ENSG00000114861|ann|Forkhead box protein P1 [Source:UniProtKB/Swiss-Prot;Acc:Q9H334] 601 2 QQQQQQQ 7 100 7 1 71 77 11 TPAVDIGAADLAHAQQQQQQALQVARQLLL VSGLKSPKRNDKQPALQQQQVATQQLAFQQ GO:0008270:zinc ion binding; --- GO:0005622:intracellular; --- >prot|ENSP00000264889|cod|ENST00000264889|gene|ENSG00000138756|ann|BMP-2-inducible protein kinase (BIKe)(EC 2.7.11.1) [Source:UniProtKB/Swiss-Prot;Acc:Q9NSY1] 676 1 QQQQQQQQQQQQQQQQQQQQQQQQQQQ 27 100 27 1 474 500 70 QPPQQHRVLQQLQQGDWRLQQLHLQHRHPH HHHHHHHHLLQDAYMQQYQHATQQQQMLQQ GO:0000166:nucleotide binding;GO:0004674:protein serine/threonine kinase activity;GO:0005524:ATP binding;GO:0016740:transferase activity;GO:0004672:protein kinase activity; GO:0006468:protein amino acid phosphorylation; GO:0005634:nucleus; --- >prot|ENSP00000386049|cod|ENST00000407073|gene|ENSG00000204406|ann|Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5) [Source:UniProtKB/Swiss-Prot;Acc:Q9P267] 1494 1 QQQQQ 5 100 5 1 980 984 65 DMSSINNTLSNHQLTHLQSLLNNNQMFPPN LLQGYQNLQAFQGQSTIPCPANNNPMACLF GO:0003677:DNA binding; --- GO:0005634:nucleus; --- >prot|ENSP00000356116|cod|ENST00000367148|gene|ENSG00000049618|ann|AT-rich interactive domain-containing protein 1B (ARID domain-containing protein 1B)(Osa homolog 2)(hOsa2)(p250R)(BRG1-binding protein hELD/OSA1)(BRG1-associated factor 250b)(BAF250B) [Source:UniProtKB/Swiss-Prot;Acc:Q8NFD5] 2289 1 QQQLNQFQQQQQQQQQQQQQQQQQQ 25 88 18 0.72 107 131 4 AAPPHQQHHHHHHAHHHHHHAHHLHHHHAL HPISNNNSLGGAGGGAPQPGPDMEQPQHGG GO:0003677:DNA binding;GO:0005488:binding; GO:0051260:protein homooligomerization; GO:0005622:intracellular;GO:0016020:membrane; --- >prot|ENSP00000365080|cod|ENST00000375915|gene|ENSG00000204442|ann|Transmembrane protein FAM155A [Source:UniProtKB/Swiss-Prot;Acc:B1AL88] 458 1 QQQQRQQQQQQQQQRQRQQQQQQRRQQ 27 81.4814814814815 9 0.333333333333333 73 99 15 ASLLFFTVLLSDHLWFCAEAKLTRARDKEH EPSWPALLASMGESSPAAQAHRLLSASSSP --- --- GO:0016020:membrane;GO:0016021:integral to membrane; --- >prot|ENSP00000343819|cod|ENST00000339475|gene|ENSG00000165588|ann|Homeobox protein OTX2 (Orthodenticle homolog 2) [Source:UniProtKB/Swiss-Prot;Acc:P32243] 297 1 QQQQQQQ 7 100 7 1 103 109 34 IFMREEVALKINLPESRVQVWFKNRRAKCR NGGQNKVRPAKKKTSPAREVSSESGTSGQF GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0008190:eukaryotic initiation factor 4E binding;GO:0043565:sequence-specific DNA binding;GO:0003677:DNA binding;GO:0030528:transcription regulator activity; GO:0006355:regulation of transcription, DNA-dependent;GO:0007275:multicellular organismal development;GO:0007411:axon guidance;GO:0008589:regulation of smoothened signaling pathway;GO:0030900:forebrain development;GO:0030901:midbrain development;GO:0040036:regulation of fibroblast growth factor receptor signaling pathway; GO:0005634:nucleus;GO:0030426:growth cone; 610125: MICROPHTHALMIA, SYNDROMIC 5; >prot|ENSP00000352904|cod|ENST00000359846|gene|ENSG00000185013|ann|Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5)(Cytosolic 5'-nucleotidase IB)(cN-IB)(cN1B)(Autoimmune infertility-related protein) [Source:UniProtKB/Swiss-Prot;Acc:Q96P26] 610 1 QQQQQ 5 100 5 1 267 271 43 RTSPTEWKSSSQRRGIYPASTQLDRNSLSE REDEDDYEAAYWASMRSFYEKNPSCSRPWP GO:0000166:nucleotide binding;GO:0000287:magnesium ion binding;GO:0008253:5'-nucleotidase activity; GO:0009117:nucleotide metabolic process; GO:0005737:cytoplasm; --- >prot|ENSP00000333367|cod|ENST00000332610|gene|ENSG00000182568|ann|DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1) [Source:UniProtKB/Swiss-Prot;Acc:Q01826] 797 1 QQQQQQQQQQQQQQQ 15 100 15 1 627 641 78 PSPTTLGKGESRGVFLPGLPTPAPWLGAAP APPPPQPQQQPQTGPRLPPRQPTVASPAES GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0043565:sequence-specific DNA binding;GO:0003677:DNA binding;GO:0016564:transcription repressor activity; GO:0006355:regulation of transcription, DNA-dependent;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0016571:histone methylation;GO:0042110:T cell activation;GO:0006325:chromatin organization;GO:0050798:activated T cell proliferation;GO:0043367:CD4-positive, alpha beta T cell differentiation;GO:0043374:CD8-positive, alpha-beta T cell differentiation;GO:0060004:reflex; GO:0000785:chromatin;GO:0005634:nucleus;GO:0005720:nuclear heterochromatin;GO:0016363:nuclear matrix; --- >prot|ENSP00000386342|cod|ENST00000409068|gene|ENSG00000115977|ann|AP2-associated protein kinase 1 (EC 2.7.11.1)(Adaptor-associated kinase 1) [Source:UniProtKB/Swiss-Prot;Acc:Q2M2I8] 674 2 QQQQQQQ 7 100 7 1 471 477 69 TPQQTPSTQAQGLPAQAQATPQHQQQLFLK PPPAQQQPAGTFYQQQQAQTQQFQAVHPAT GO:0000166:nucleotide binding;GO:0004674:protein serine/threonine kinase activity;GO:0005524:ATP binding;GO:0016740:transferase activity;GO:0004672:protein kinase activity;GO:0004713:protein tyrosine kinase activity; GO:0006468:protein amino acid phosphorylation; GO:0005886:plasma membrane;GO:0005905:coated pit; --- >prot|ENSP00000386342|cod|ENST00000409068|gene|ENSG00000115977|ann|AP2-associated protein kinase 1 (EC 2.7.11.1)(Adaptor-associated kinase 1) [Source:UniProtKB/Swiss-Prot;Acc:Q2M2I8] 674 2 QQQQQQQQQQQQQQ 14 100 14 1 533 546 79 VHPATQKPAIAQFPVVSQGGSQQQLMQNFY LATALHQQQLMTQQAALQQKPTMAAGQQPQ GO:0000166:nucleotide binding;GO:0004674:protein serine/threonine kinase activity;GO:0005524:ATP binding;GO:0016740:transferase activity;GO:0004672:protein kinase activity;GO:0004713:protein tyrosine kinase activity; GO:0006468:protein amino acid phosphorylation; GO:0005886:plasma membrane;GO:0005905:coated pit; --- >prot|ENSP00000349606|cod|ENST00000357094|gene|ENSG00000157212|ann|PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein) [Source:UniProtKB/Swiss-Prot;Acc:Q6ZW49] 893 3 QLQQQQQQQISQQ 13 76.9230769230769 7 0.538461538461538 374 386 41 PETHMLQQQQQAQQQQQQHPVLHLQPQQIM PYPQQPPHPFSQQQQQQQQPPPSPQQHQLF GO:0045735:nutrient reservoir activity; GO:0031424:keratinization; GO:0005622:intracellular;GO:0005737:cytoplasm; 104300: ALZHEIMER DISEASE; >prot|ENSP00000349606|cod|ENST00000357094|gene|ENSG00000157212|ann|PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein) [Source:UniProtKB/Swiss-Prot;Acc:Q6ZW49] 893 3 QQQQQQQQ 8 100 8 1 398 405 44 QPQQIMQLQQQQQQQISQQPYPQQPPHPFS PPPSPQQHQLFGHDPAVEIPEEGFLLGCVF GO:0045735:nutrient reservoir activity; GO:0031424:keratinization; GO:0005622:intracellular;GO:0005737:cytoplasm; 104300: ALZHEIMER DISEASE; >prot|ENSP00000323846|cod|ENST00000326184|gene|ENSG00000179899|ann|Putative uncharacterized protein DKFZp686A1782 [Source:UniProtKB/TrEMBL;Acc:Q6N083] 1004 2 QQQQQ 5 100 5 1 381 385 37 MNLTRTATPAPSQTLISSATYTQIQPHSLI IHLQQKQVVIQQQIAIHHQQQFQHWQSQLL GO:0008270:zinc ion binding; --- GO:0005634:nucleus; --- >prot|ENSP00000323846|cod|ENST00000326184|gene|ENSG00000179899|ann|Putative uncharacterized protein DKFZp686A1782 [Source:UniProtKB/TrEMBL;Acc:Q6N083] 1004 2 QLAQQQQQQQQQQQQQQQPQ 20 85 15 0.75 422 441 42 QVVIQQQIAIHHQQQFQHWQSQLLHTATHL ATTLTAPQPPQVPPTQQVPPSQSQQQAQTL GO:0008270:zinc ion binding; --- GO:0005634:nucleus; --- >prot|ENSP00000301015|cod|ENST00000301015|gene|ENSG00000103335|ann|Protein FAM38A (Membrane protein induced by beta-amyloid treatment)(Mib) [Source:UniProtKB/Swiss-Prot;Acc:Q92508] 2089 1 QQEHQQQQQ 9 77.7777777777778 5 0.555555555555556 309 317 14 MEHVSLPGTRLPRWAHRQDAVSGTPLLREE EEEEEEEDSRDEGLGVATPHQATQVPEGAA --- --- GO:0016020:membrane;GO:0016021:integral to membrane;GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0033116:ER-Golgi intermediate compartment membrane; --- >prot|ENSP00000355260|cod|ENST00000361131|gene|ENSG00000198729|ann|Protein phosphatase 1 regulatory subunit 14C (PKC-potentiated PP1 inhibitory protein)(Kinase-enhanced PP1 inhibitor)(Serologically defined breast cancer antigen NY-BR-81) [Source:UniProtKB/Swiss-Prot;Acc:Q8TAE6] 165 1 QVQQQQQ 7 85.7142857142857 5 0.714285714285714 58 64 35 GGAGGSPGSSSGSGSSREDSAPVATAAAAG RRHQQGKVTVKYDRKELRKRLVLEEWIVEQ GO:0004865:protein serine/threonine phosphatase inhibitor activity;GO:0005515:protein binding; GO:0042325:regulation of phosphorylation; GO:0016020:membrane;GO:0005737:cytoplasm; --- >prot|ENSP00000331157|cod|ENST00000330909|gene|ENSG00000151276|ann|Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1)(BAP-1)(Membrane-associated guanylate kinase inverted 1)(MAGI-1)(Atrophin-1-interacting protein 3)(AIP3)(WW domain-containing protein 3)(WWP3)(Trinucleotide repeat-containing gene 19 protein) [Source:UniProtKB/Swiss-Prot;Acc:Q96QZ7] 1287 1 QLEQQQQQQQQQQQQQQQQQQQQ 23 91.304347826087 20 0.869565217391304 399 421 31 EDPVYGIYYVDHINRKTQYENPVLEAKRKK TEEWTEDHSALVPPVIPNHPPSNPEPAREV GO:0005515:protein binding; --- --- --- >prot|ENSP00000380019|cod|ENST00000396801|gene|ENSG00000126746|ann|Zinc finger protein 384 (Nuclear matrix transcription factor 4)(Nuclear matrix protein 4)(Trinucleotide repeat-containing gene 1 protein)(CAG repeat protein 1)(CAS-interacting zinc finger protein) [Source:UniProtKB/Swiss-Prot;Acc:Q8TF68] 577 1 QQQQQQQQQQQQQQQQPPPHFQ 22 77.2727272727273 16 0.727272727272727 501 522 86 AAVAQAQAQAQAQAQAQAQAQAQAQASQAS SPGAAPQGGGGGDSNPNPPPQCSFDLTPYK GO:0008270:zinc ion binding; --- GO:0005622:intracellular; --- >prot|ENSP00000373067|cod|ENST00000383573|gene|ENSG00000206485|ann|KIAA1949 [Source:UniProtKB/TrEMBL;Acc:B7ZCV7] 613 1 QERQQQQQQQQ 11 81.8181818181818 8 0.727272727272727 93 103 15 GTVEAGPPDPDESAVLLEAIGPVHQNRFIR RSEELLAERKPGPLEARERRPSPGEMRDQS --- --- --- --- >prot|ENSP00000292733|cod|ENST00000292733|gene|ENSG00000099917|ann|Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15)(Positive cofactor 2 glutamine/Q-rich-associated protein)(PC2 glutamine/Q-rich-associated protein)(TPA-inducible gene 1 protein)(TIG-1)(Activator-recruited cofactor 105 kDa component)(ARC105)(CTG repeat protein 7a)(Trinucleotide repeat-containing gene 7 protein) [Source:UniProtKB/Swiss-Prot;Acc:Q96RN5] 748 2 QQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQ 58 75.8620689655172 11 0.189655172413793 161 218 21 PGTSGMAPHSMAVVSTATPQTQLQLQQVAL HLIKLHHQNQQQIQQQQQQLQRIAQLQLQQ GO:0005199:structural constituent of cell wall; --- --- --- >prot|ENSP00000292733|cod|ENST00000292733|gene|ENSG00000099917|ann|Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15)(Positive cofactor 2 glutamine/Q-rich-associated protein)(PC2 glutamine/Q-rich-associated protein)(TPA-inducible gene 1 protein)(TIG-1)(Activator-recruited cofactor 105 kDa component)(ARC105)(CTG repeat protein 7a)(Trinucleotide repeat-containing gene 7 protein) [Source:UniProtKB/Swiss-Prot;Acc:Q96RN5] 748 2 QNQQQIQQQQQQLQ 14 78.5714285714286 6 0.428571428571429 226 239 30 MQQQFQAVVQQQQQLQQQQQQQQHLIKLHH RIAQLQLQQQQQQQQQQQQQQQQALQAQPP GO:0005199:structural constituent of cell wall; --- --- --- >prot|ENSP00000339926|cod|ENST00000344029|gene|ENSG00000143502|ann|Sushi domain-containing protein 4 Precursor [Source:UniProtKB/Swiss-Prot;Acc:Q5VX71] 290 1 QQQQQQQPQSPQ 12 75 7 0.583333333333333 16 27 5 MYHGMNPSNGDGFLEQQQQQQQPQSPQRLL RLLAVILWFQLALCFGPAQLTGGFDDLQVC --- --- GO:0016020:membrane;GO:0016021:integral to membrane; --- >prot|ENSP00000326900|cod|ENST00000315183|gene|ENSG00000090905|ann|Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26)(Glycine-tryptophan protein of 182 kDa)(GW182 autoantigen)(Protein GW1)(EMSY interactor protein) [Source:UniProtKB/Swiss-Prot;Acc:Q8NDV7] 1913 1 QQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQ 35 77.1428571428572 8 0.228571428571429 93 127 4 VSQPQPANSNNGTSTATSTNNNAKRATANN ALPRYPREVPPRFRHQEHKQLLKRGQHFPV GO:0000166:nucleotide binding;GO:0003723:RNA binding;GO:0003676:nucleic acid binding; --- GO:0005737:cytoplasm; --- >prot|ENSP00000378969|cod|ENST00000395605|gene|ENSG00000085224|ann|Transcriptional regulator ATRX (EC 3.6.1.-)(ATP-dependent helicase ATRX)(X-linked helicase II)(X-linked nuclear protein)(XNP)(Znf-HX) [Source:UniProtKB/Swiss-Prot;Acc:P46100] 2492 1 QQQYNQQQQQQ 11 81.8181818181818 6 0.545454545454545 2415 2425 96 KRREAIYNDVLTKQQMLISCVQRILMNRRL MTYQQATLGHLMMPKPPNLIMNPSNYQQID GO:0005515:protein binding;GO:0008270:zinc ion binding; --- --- --- >prot|ENSP00000363822|cod|ENST00000374690|gene|ENSG00000169083|ann|Androgen receptor (Dihydrotestosterone receptor)(Nuclear receptor subfamily 3 group C member 4) [Source:UniProtKB/Swiss-Prot;Acc:P10275] 920 2 QQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQ 34 85.2941176470588 23 0.676470588235294 58 91 6 QSVREVIQNPGPRHPEAASAAPPGASLLLL GEDGSPQAHRRGPTGYLVLDEEQQPSQPQS GO:0003677:DNA binding;GO:0004879:ligand-dependent nuclear receptor activity;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0003707:steroid hormone receptor activity;GO:0008270:zinc ion binding;GO:0043565:sequence-specific DNA binding; GO:0006355:regulation of transcription, DNA-dependent; GO:0005634:nucleus; 313200: SPINAL AND BULBAR MUSCULAR ATROPHY, X-LINKED 1;312300: ANDROGEN INSENSITIVITY, PARTIAL;300633: HYPOSPADIAS 1, X-LINKED;300068: ANDROGEN INSENSITIVITY SYNDROME;176807: PROSTATE CANCER; >prot|ENSP00000363822|cod|ENST00000374690|gene|ENSG00000169083|ann|Androgen receptor (Dihydrotestosterone receptor)(Nuclear receptor subfamily 3 group C member 4) [Source:UniProtKB/Swiss-Prot;Acc:P10275] 920 2 QLLQQQQQ 8 75 5 0.625 192 199 20 STLSLLGPTFPGLSSCSADLKDILSEASTM EAVSEGSSSGRAREASGAPTSSKDNYLGGT GO:0003677:DNA binding;GO:0004879:ligand-dependent nuclear receptor activity;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0003707:steroid hormone receptor activity;GO:0008270:zinc ion binding;GO:0043565:sequence-specific DNA binding; GO:0006355:regulation of transcription, DNA-dependent; GO:0005634:nucleus; 313200: SPINAL AND BULBAR MUSCULAR ATROPHY, X-LINKED 1;312300: ANDROGEN INSENSITIVITY, PARTIAL;300633: HYPOSPADIAS 1, X-LINKED;300068: ANDROGEN INSENSITIVITY SYNDROME;176807: PROSTATE CANCER; >prot|ENSP00000384990|cod|ENST00000402544|gene|ENSG00000171988|ann|Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-)(Jumonji domain-containing protein 1C)(Thyroid receptor-interacting protein 8)(TRIP-8) [Source:UniProtKB/Swiss-Prot;Acc:Q15652] 2303 2 QQQQQ 5 100 5 1 83 87 3 AVHSHYTRAQANSPRPAMNSQAAVPKQNTH RSIRPNKRKGSDSSIPDEEKMKEEKYDYIS GO:0005506:iron ion binding;GO:0005515:protein binding;GO:0008270:zinc ion binding;GO:0016491:oxidoreductase activity;GO:0016702:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0046872:metal ion binding;GO:0046966:thyroid hormone receptor binding;GO:0003824:catalytic activity; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0016568:chromatin modification;GO:0055114:oxidation reduction;GO:0005975:carbohydrate metabolic process; GO:0005622:intracellular;GO:0005634:nucleus; --- >prot|ENSP00000384990|cod|ENST00000402544|gene|ENSG00000171988|ann|Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-)(Jumonji domain-containing protein 1C)(Thyroid receptor-interacting protein 8)(TRIP-8) [Source:UniProtKB/Swiss-Prot;Acc:Q15652] 2303 2 QQQQQ 5 100 5 1 612 616 26 PGVPTASLLGGHPRLESAHASSLSHLALAH LLQHQSPHLLGQAHPSASYNQLGLYPIIWQ GO:0005506:iron ion binding;GO:0005515:protein binding;GO:0008270:zinc ion binding;GO:0016491:oxidoreductase activity;GO:0016702:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0046872:metal ion binding;GO:0046966:thyroid hormone receptor binding;GO:0003824:catalytic activity; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0016568:chromatin modification;GO:0055114:oxidation reduction;GO:0005975:carbohydrate metabolic process; GO:0005622:intracellular;GO:0005634:nucleus; --- >prot|ENSP00000333560|cod|ENST00000327590|gene|ENSG00000114861|ann|Neuron-specific protein family member 1 (Brain neuron cytoplasmic protein 1) [Source:UniProtKB/Swiss-Prot;Acc:P42857] 566 2 QQQQQQQ 7 100 7 1 71 77 12 TPAVDIGAADLAHAQQQQQQALQVARQLLL VSGLKSPKRNDKQPALQVPVSVAMMTPQVI GO:0008270:zinc ion binding; --- GO:0005622:intracellular; --- >prot|ENSP00000355925|cod|ENST00000366958|gene|ENSG00000117707|ann|Prospero homeobox protein 1 (Homeobox prospero-like protein PROX1)(PROX-1) [Source:UniProtKB/Swiss-Prot;Acc:Q92786] 737 1 QQQQQSFQQ 9 77.7777777777778 5 0.555555555555556 215 223 29 RGNENEREMAPQSVSPRESYRENKRKQKLP LVSARKEQKREERRQLKQQLEDMQKQLRQL GO:0003677:DNA binding;GO:0030528:transcription regulator activity; GO:0007275:multicellular organismal development;GO:0045449:regulation of transcription; GO:0005634:nucleus; --- >prot|ENSP00000350719|cod|ENST00000358025|gene|ENSG00000054654|ann|Nesprin-2 (Nuclear envelope spectrin repeat protein 2)(Synaptic nuclear envelope protein 2)(Syne-2)(Nucleus and actin connecting element protein)(Protein NUANCE) [Source:UniProtKB/Swiss-Prot;Acc:Q8WXH0] 6907 1 QQQQQHLQ 8 75 5 0.625 2643 2650 38 QIQKKYSQQVVEYDEFTTLMNKVQDTEISL LRLKSPEERAGNQSMIALTTDLQATKHGFS GO:0005515:protein binding;GO:0005096:GTPase activator activity;GO:0008083:growth factor activity;GO:0003779:actin binding; GO:0007165:signal transduction; GO:0016021:integral to membrane; --- >prot|ENSP00000379122|cod|ENST00000395776|gene|ENSG00000108557|ann|Retinoic acid-induced protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q7Z5J4] 1993 1 QQQQQQQQQQQQQQALQ 17 88.2352941176471 14 0.823529411764706 278 294 13 DRPLTASSSLAPGQRVQNLHAYQSGRLSYD SRHHAQETLHYQNLAKYQHYGQQGQGYCQP GO:0005515:protein binding;GO:0008270:zinc ion binding;GO:0046872:metal ion binding; --- GO:0005634:nucleus;GO:0005737:cytoplasm; 182290: SMITH-MAGENIS SYNDROME; >prot|ENSP00000314343|cod|ENST00000315588|gene|ENSG00000063322|ann|Mediator of RNA polymerase II transcription subunit 29 (Mediator complex subunit 29)(Intersex-like protein) [Source:UniProtKB/Swiss-Prot;Acc:Q9NX70] 221 1 QQQQQ 5 100 5 1 69 73 31 SGPSSAGGPGPQQQPQPPAQLVGPAQSGLL DFDPVQRYKMLIPQLKESLQTLMKVAAQNL GO:0005515:protein binding; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent; GO:0005634:nucleus; --- >prot|ENSP00000374292|cod|ENST00000389641|gene|ENSG00000176155|ann|Coiled-coil domain-containing protein 57 [Source:UniProtKB/Swiss-Prot;Acc:Q2TAC2] 915 1 QQQQQ 5 100 5 1 117 121 12 ARRAEVSELKIEAAKLRQALAREARKVEEL LAFQEHRLELERVHSDKNGEIDHHREQYEN --- --- --- --- >prot|ENSP00000238647|cod|ENST00000238647|gene|ENSG00000119669|ann|Enhanced at puberty protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9H1B7] 796 1 QQQQQQQQQQQQQQQQQQQQQQQQQ 25 100 25 1 103 127 12 PPPVGVKTVALSAKEAAAAAAAAAAAAAAA LNHVDGSSKPAVLAAPSGLERYGLSAAAAA GO:0003674:molecular_function;GO:0050825:ice binding;GO:0005515:protein binding;GO:0008270:zinc ion binding;GO:0004176:ATP-dependent peptidase activity;GO:0004252:serine-type endopeptidase activity; GO:0008150:biological_process;GO:0042309:homoiothermy;GO:0050826:response to freezing;GO:0006508:proteolysis; GO:0005634:nucleus; --- >prot|ENSP00000353362|cod|ENST00000360228|gene|ENSG00000141837|ann|Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage-gated calcium channel subunit alpha Cav2.1)(Calcium channel, L type, alpha-1 polypeptide isoform 4)(Brain calcium channel I)(BI) [Source:UniProtKB/Swiss-Prot;Acc:O00555] 2506 1 QQQQQQQQQQQQQ 13 100 13 1 2313 2325 92 RRQLPQTPSTPRPHVSYSPVIRKAGGSGPP AVARPGRAATSGPRRYPGPTAEPLAGDRPP GO:0005244:voltage-gated ion channel activity;GO:0005245:voltage-gated calcium channel activity;GO:0005509:calcium ion binding;GO:0005515:protein binding;GO:0019905:syntaxin binding;GO:0005249:voltage-gated potassium channel activity;GO:0005216:ion channel activity;GO:0003677:DNA binding; GO:0006811:ion transport;GO:0006816:calcium ion transport;GO:0007204:elevation of cytosolic calcium ion concentration;GO:0008219:cell death;GO:0006813:potassium ion transport; GO:0005886:plasma membrane;GO:0016020:membrane;GO:0016021:integral to membrane;GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0005891:voltage-gated calcium channel complex;GO:0008076:voltage-gated potassium channel complex;GO:0042995:cell projection; 183086: SPINOCEREBELLAR ATAXIA 6;141500: MIGRAINE, FAMILIAL HEMIPLEGIC, 1;108500: EPISODIC ATAXIA, TYPE 2; >prot|ENSP00000355800|cod|ENST00000366835|gene|ENSG00000196187|ann|Transmembrane protein 63A [Source:UniProtKB/Swiss-Prot;Acc:O94886] 807 1 QQQQQQ 6 100 6 1 770 775 95 EAEAHMPPPFTPYVPRILNGLASERTALSP TYGAIHNISGTIPGQCLAQSATGSVAAAPQ GO:0003676:nucleic acid binding; --- GO:0016020:membrane;GO:0016021:integral to membrane; --- >prot|ENSP00000357503|cod|ENST00000368517|gene|ENSG00000171772|ann|Synaptonemal complex central element protein 1 (Cancer/testis antigen 76)(CT76) [Source:UniProtKB/Swiss-Prot;Acc:Q8N0S2] 282 1 QQQQQKRQ 8 75 5 0.625 233 240 82 TVQLFQEEHRKAEELLAAAAQRHQQLQQKC RLKEELEKHGMQVPAQAQSTQEEEAGPGDV GO:0005515:protein binding; GO:0007049:cell cycle;GO:0007126:meiosis;GO:0007128:meiotic prophase I;GO:0051301:cell division; GO:0000795:synaptonemal complex;GO:0000801:central element;GO:0005634:nucleus; --- >prot|ENSP00000234389|cod|ENST00000234389|gene|ENSG00000116032|ann|Glutamate [NMDA] receptor subunit 3B Precursor (N-methyl-D-aspartate receptor subtype NR3B)(NMDAR3B)(NR3B) [Source:UniProtKB/Swiss-Prot;Acc:O60391] 1043 1 QQQQQQDQ 8 87.5 6 0.75 907 914 86 QKIHRALNTEPPEGSKEETAEAEPSGPEVE PTAPEGWKRARRAVDKERRVRFLLEPAVVV GO:0000287:magnesium ion binding;GO:0004872:receptor activity;GO:0004970:ionotropic glutamate receptor activity;GO:0005216:ion channel activity;GO:0005234:extracellular-glutamate-gated ion channel activity;GO:0005262:calcium channel activity;GO:0005509:calcium ion binding;GO:0005215:transporter activity; GO:0006811:ion transport;GO:0051205:protein insertion into membrane;GO:0051924:regulation of calcium ion transport;GO:0006810:transport; GO:0005886:plasma membrane;GO:0016020:membrane;GO:0016021:integral to membrane;GO:0017146:N-methyl-D-aspartate selective glutamate receptor complex;GO:0030054:cell junction;GO:0030288:outer membrane-bounded periplasmic space;GO:0043025:neuronal cell body;GO:0045202:synapse;GO:0045211:postsynaptic membrane; --- >prot|ENSP00000351686|cod|ENST00000358825|gene|ENSG00000170325|ann|PR domain zinc finger protein 10 (PR domain-containing protein 10)(Tristanin) [Source:UniProtKB/Swiss-Prot;Acc:Q9NQV6] 1160 1 QGQALQQQQQQQQ 13 76.9230769230769 8 0.615384615384615 1027 1039 88 AQVSGQPLSPSAQQAQQGLSPSHIQGSSST NSSVQHTYLPSAWNSFRGYSSEIQMMTLPP GO:0003676:nucleic acid binding;GO:0008270:zinc ion binding;GO:0003677:DNA binding; --- GO:0005622:intracellular; --- >prot|ENSP00000384160|cod|ENST00000401878|gene|ENSG00000184863|ann|RNA-binding protein 33 (RNA-binding motif protein 33)(Proline-rich protein 8) [Source:UniProtKB/Swiss-Prot;Acc:Q96EV2] 1170 1 QQQQQ 5 100 5 1 829 833 70 RLREEILKQKELRRQQQAGARKKELLERLA LYAPPPPAEQEEQALSPSPTNGNPLLPFPG --- GO:0007186:G-protein coupled receptor protein signaling pathway; GO:0016021:integral to membrane; --- >prot|ENSP00000050961|cod|ENST00000050961|gene|ENSG00000091656|ann|Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4)(ZFH-4) [Source:UniProtKB/Swiss-Prot;Acc:Q86UP3] 3567 1 QQQQQQQ 7 100 7 1 1778 1784 49 LQILQQQAQQYQATQPQLQPQKQQQQPPPP ASKLLKQEQSNIVSADCQIMKDVPSYKEAE GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0043565:sequence-specific DNA binding;GO:0003676:nucleic acid binding;GO:0008270:zinc ion binding;GO:0030528:transcription regulator activity;GO:0005179:hormone activity; GO:0006355:regulation of transcription, DNA-dependent; GO:0005622:intracellular;GO:0005576:extracellular region;GO:0005634:nucleus; --- >prot|ENSP00000218894|cod|ENST00000350612|gene|ENSG00000102710|ann|Protein FAM48A (p38-interacting protein)(p38IP) [Source:UniProtKB/Swiss-Prot;Acc:Q8NEM7] 779 2 QQQQQQLSQ 9 77.7777777777778 6 0.666666666666667 636 644 81 GVPFGLKNTSSLRPLNLLQLPGGSLIFNTL FTPQQPQQPTTCSPQQPGEQGSEQGSTSQE GO:0005515:protein binding; GO:0007275:multicellular organismal development;GO:0007369:gastrulation; --- --- >prot|ENSP00000218894|cod|ENST00000350612|gene|ENSG00000102710|ann|Protein FAM48A (p38-interacting protein)(p38IP) [Source:UniProtKB/Swiss-Prot;Acc:Q8NEM7] 779 2 QQQQQQIQQ 9 88.8888888888889 6 0.666666666666667 727 735 93 QAAVLSQLGSAENRPEQSLPQQRFQLSSAF LRFLQHQMAMAAAAAQTAQLHHHRHTGSQS GO:0005515:protein binding; GO:0007275:multicellular organismal development;GO:0007369:gastrulation; --- --- >prot|ENSP00000302114|cod|ENST00000303204|gene|ENSG00000169230|ann|PRELI domain-containing protein 1, mitochondrial Precursor (Px19-like protein)(25 kDa protein of relevant evolutionary and lymphoid interest) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y255] 219 1 QQQQQQ 6 100 6 1 212 217 96 AKEAKEKAKETALAATEKAKDLASKAATKK FV --- GO:0006955:immune response;GO:0007275:multicellular organismal development; GO:0005739:mitochondrion; --- >prot|ENSP00000313316|cod|ENST00000327122|gene|ENSG00000196782|ann|Mastermind-like protein 3 (Mam-3) [Source:UniProtKB/Swiss-Prot;Acc:Q96JK9] 543 1 QQQQQQQQQQQQQQQQQQPPPPQLQ 25 80 18 0.72 477 501 87 KPLTHFNADLSQRMTPPVANPNKNPLMPYI APRAHLSEDQKRLLLMKQKGVMNQPMAYAA GO:0003677:DNA binding;GO:0004879:ligand-dependent nuclear receptor activity; GO:0006355:regulation of transcription, DNA-dependent; GO:0005634:nucleus; --- >prot|ENSP00000268712|cod|ENST00000268712|gene|ENSG00000141027|ann|Nuclear receptor corepressor 1 (N-CoR1)(N-CoR) [Source:UniProtKB/Swiss-Prot;Acc:O75376] 2440 1 QQQQQQQ 7 100 7 1 58 64 2 TFPNTRHQQEFAVPDYRSSHLEVSQASQLL LRRRPSLLSEFHPGSDRPQERRTSYEPFHP GO:0003677:DNA binding; --- --- --- >prot|ENSP00000296452|cod|ENST00000296452|gene|ENSG00000164061|ann|Protein bassoon (Zinc finger protein 231) [Source:UniProtKB/Swiss-Prot;Acc:Q9UPA5] 3926 1 QPQTQQQQQ 9 77.7777777777778 5 0.555555555555556 3775 3783 96 PQLQGRQAAPGPQQSQSPSSRQIPSGAASR GLGLQPPQQALTQARLQQQSQPTTRGSAPA GO:0008270:zinc ion binding;GO:0046872:metal ion binding;GO:0005515:protein binding; GO:0007268:synaptic transmission; GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0005856:cytoskeleton;GO:0019717:synaptosome;GO:0030054:cell junction;GO:0045202:synapse; --- >prot|ENSP00000376355|cod|ENST00000392576|gene|ENSG00000155111|ann|Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22)(CDC2-related protein kinase 6)(Death-preventing kinase)(Cyclin-dependent kinase 11) [Source:UniProtKB/Swiss-Prot;Acc:Q9BWU1] 441 1 QQQQQNQHQQ 10 80 5 0.5 311 320 70 TLDVFAGCQIPYPKREFLNEDDPEEKGDKN PTAPPQQAAAPPQAPPPQQNSTQTNGTAGG GO:0000166:nucleotide binding;GO:0004693:cyclin-dependent protein kinase activity;GO:0005515:protein binding;GO:0005524:ATP binding;GO:0016740:transferase activity;GO:0004672:protein kinase activity;GO:0004713:protein tyrosine kinase activity;GO:0004674:protein serine/threonine kinase activity; GO:0006468:protein amino acid phosphorylation; GO:0005634:nucleus; --- >prot|ENSP00000252891|cod|ENST00000252891|gene|ENSG00000105245|ann|Numb-like protein (Numb-R) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y6R0] 609 1 QVAKAQQQQQQQQQQQQQQQQQQQQ 25 84 20 0.8 422 446 69 GEPSVPPAAAFQPGHKRTPSEAERWLEEVS AASVAPVPTMPPALQPFPAPVGPFDAAPAQ GO:0005515:protein binding;GO:0003677:DNA binding;GO:0004879:ligand-dependent nuclear receptor activity; GO:0007399:nervous system development;GO:0007405:neuroblast proliferation;GO:0007409:axonogenesis;GO:0030900:forebrain development;GO:0006355:regulation of transcription, DNA-dependent;GO:0034332:adherens junction organization; GO:0005634:nucleus;GO:0005737:cytoplasm; --- >prot|ENSP00000330659|cod|ENST00000331159|gene|ENSG00000174111|ann|Suppressor of cytokine signaling 7 (SOCS-7)(Nck, Ash and phospholipase C gamma-binding protein)(Nck-associated protein 4)(NAP-4) [Source:UniProtKB/Swiss-Prot;Acc:O14512] 581 1 QQQQQQQQ 8 100 8 1 180 187 30 LLLQPPGPELPPVPFPLQDLVPLGRLSRGE PPPPPPPPGPLRPLAGPSRKGSFKIRLSRL GO:0005515:protein binding;GO:0017124:SH3 domain binding;GO:0005199:structural constituent of cell wall; GO:0007242---GO:0008150:biological_process;GO:0008286:insulin receptor signaling pathway;GO:0009968:negative regulation of signal transduction;GO:0016567:protein ubiquitination;GO:0019941:modification-dependent protein catabolic process;GO:0040008:regulation of growth;GO:0045444:fat cell differentiation; GO:0005886:plasma membrane;GO:0005575:cellular_component;GO:0005737:cytoplasm; --- >prot|ENSP00000263253|cod|ENST00000263253|gene|ENSG00000100393|ann|Histone acetyltransferase p300 (p300 HAT)(EC 2.3.1.48)(E1A-associated protein p300) [Source:UniProtKB/Swiss-Prot;Acc:Q09472] 2414 1 QQMMQQQQQQ 10 80 6 0.6 2186 2195 90 PPMGGMSPQAQQMNMNHNTMPSQFRDILRR GAGPGIGPGMANHNQFQQPQGVGYPPQQQQ GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0003713:transcription coactivator activity;GO:0004402:histone acetyltransferase activity;GO:0008022:protein C-terminus binding;GO:0008270:zinc ion binding;GO:0016407:acetyltransferase activity;GO:0016740:transferase activity;GO:0042975:peroxisome proliferator activated receptor binding;GO:0046872:metal ion binding;GO:0003712:transcription cofactor activity;GO:0005515:protein binding;GO:0016563:transcription activator activity;GO:0008134:transcription factor binding; GO:0001666:response to hypoxia;GO:0001756:somitogenesis;GO:0006355:regulation of transcription, DNA-dependent;GO:0006915:apoptosis;GO:0007049:cell cycle;GO:0007165:signal transduction;GO:0007399:nervous system development;GO:0007507:heart development;GO:0007519:skeletal muscle tissue development;GO:0009887:organ morphogenesis;GO:0016573:histone acetylation;GO:0018076:N-terminal peptidyl-lysine acetylation;GO:0030324:lung development;GO:0042592:homeostatic process;GO:0044419:interspecies interaction between organisms;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0051091:positive regulation of transcription factor activity;GO:0045449:regulation of transcription; GO:0000123:histone acetyltransferase complex;GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0005667:transcription factor complex; 180849: RUBINSTEIN-TAYBI SYNDROME;114500: COLORECTAL CANCER; >prot|ENSP00000365188|cod|ENST00000376020|gene|ENSG00000158352|ann|Protein Shroom4 (Second homolog of apical protein) [Source:UniProtKB/Swiss-Prot;Acc:Q9ULL8] 1493 1 QQQKQQQQQQKQQ 13 84.6153846153846 6 0.461538461538462 1119 1131 74 SDLLGARKKAFPPPRPPPPNWEKYRLFRAA EEEEEEEEEEEEEEEEEEEEAEEEEEELPP GO:0005515:protein binding;GO:0051015:actin filament binding; GO:0007015:actin filament organization;GO:0007275:multicellular organismal development;GO:0007420:brain development;GO:0050890:cognition; GO:0001725:stress fiber;GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0009925:basal plasma membrane;GO:0016324:apical plasma membrane;GO:0016460:myosin II complex;GO:0030864:cortical actin cytoskeleton;GO:0031941:filamentous actin; 300434: STOCCO DOS SANTOS X-LINKED MENTAL RETARDATION SYNDROME; >prot|ENSP00000304895|cod|ENST00000305123|gene|ENSG00000169047|ann|Insulin receptor substrate 1 (IRS-1) [Source:UniProtKB/Swiss-Prot;Acc:P35568] 1242 1 QQQQQQ 6 100 6 1 877 882 70 TAAQTNSRLARPTRLSLGDPKASTLPRARE PLLHPPEPKSPGEYVNIEFGSDQSGYLSGP GO:0004871:signal transducer activity;GO:0005069:transmembrane receptor protein tyrosine kinase docking protein activity;GO:0005080:protein kinase C binding;GO:0005158:insulin receptor binding;GO:0005159:insulin-like growth factor receptor binding;GO:0005515:protein binding;GO:0042169:SH2 domain binding;GO:0042301:phosphate binding;GO:0043548:phosphoinositide 3-kinase binding;GO:0019901:protein kinase binding; GO:0002053:positive regulation of mesenchymal cell proliferation;GO:0006006:glucose metabolic process;GO:0007165:signal transduction;GO:0014065:phosphoinositide 3-kinase cascade;GO:0030335:positive regulation of cell migration;GO:0030879:mammary gland development;GO:0032000:positive regulation of fatty acid beta-oxidation;GO:0032869:cellular response to insulin stimulus;GO:0042593:glucose homeostasis;GO:0043434:response to peptide hormone stimulus;GO:0043491:protein kinase B signaling cascade;GO:0043552:positive regulation of phosphoinositide 3-kinase activity;GO:0045725:positive regulation of glycogen biosynthetic process;GO:0046326:positive regulation of glucose import;GO:0046627:negative regulation of insulin receptor signaling pathway;GO:0046628:positive regulation of insulin receptor signaling pathway;GO:0048009:insulin-like growth factor receptor signaling pathway; GO:0005886:plasma membrane;GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0005792:microsome;GO:0005899:insulin receptor complex;GO:0005901:caveola; 125853: DIABETES MELLITUS, NONINSULIN-DEPENDENT; >prot|ENSP00000357676|cod|ENST00000368687|gene|ENSG00000160679|ann|Uncharacterized protein C1orf77 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y3Y2] 223 1 QQQQQ 5 100 5 1 17 21 7 MLKNKQPTPVNIRASMQQQQQLASARNRRL LASARNRRLAQQMENRPSVQAALKLKQSLK GO:0005515:protein binding; --- --- --- >prot|ENSP00000305860|cod|ENST00000352301|gene|ENSG00000138668|ann|Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0)(AU-rich element RNA-binding protein 1) [Source:UniProtKB/Swiss-Prot;Acc:Q14103] 336 1 QYQQQQQ 7 85.7142857142857 5 0.714285714285714 243 249 72 EEEPVKKIMEKKYHNVGLSKCEIKVAMSKE WGSRGGFAGRARGRGGGPSQNWNQGYSNYW GO:0000166:nucleotide binding;GO:0003677:DNA binding;GO:0003723:RNA binding;GO:0005515:protein binding;GO:0016563:transcription activator activity;GO:0042162:telomeric DNA binding;GO:0050825:ice binding;GO:0003676:nucleic acid binding; GO:0000398:nuclear mRNA splicing, via spliceosome;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0006396:RNA processing;GO:0006401:RNA catabolic process;GO:0008150:biological_process;GO:0042309:homoiothermy;GO:0050826:response to freezing; GO:0005634:nucleus;GO:0005694:chromosome;GO:0030530:heterogeneous nuclear ribonucleoprotein complex; --- >prot|ENSP00000271915|cod|ENST00000271915|gene|ENSG00000143603|ann|Small conductance calcium-activated potassium channel protein 3 (SKCa3)(SK3) [Source:UniProtKB/Swiss-Prot;Acc:Q9UGI6] 731 3 QQQQQQQQQQQQ 12 100 12 1 30 41 4 MDTSGHFHDSGVGDLDEDPKCPCPSSGDEQ PPPPAPPAAPQQPLGPSLQPQPPQLQQQQQ GO:0005249:voltage-gated potassium channel activity;GO:0005516:calmodulin binding;GO:0015269:calcium-activated potassium channel activity; GO:0006813:potassium ion transport; GO:0016021:integral to membrane;GO:0008076:voltage-gated potassium channel complex; --- >prot|ENSP00000271915|cod|ENST00000271915|gene|ENSG00000143603|ann|Small conductance calcium-activated potassium channel protein 3 (SKCa3)(SK3) [Source:UniProtKB/Swiss-Prot;Acc:Q9UGI6] 731 3 QPQPPQLQQQQQQQQQQQQQQ 21 80.9523809523809 14 0.666666666666667 60 80 8 QQQQQQQQQQQQPPPPAPPAAPQQPLGPSL PPHPLSQLAQLQSQPVHPGLLHSSPTAFRA GO:0005249:voltage-gated potassium channel activity;GO:0005516:calmodulin binding;GO:0015269:calcium-activated potassium channel activity; GO:0006813:potassium ion transport; GO:0016021:integral to membrane;GO:0008076:voltage-gated potassium channel complex; --- >prot|ENSP00000258963|cod|ENST00000258963|gene|ENSG00000136451|ann|Vascular endothelial zinc finger 1 (Zinc finger protein 161)(Putative transcription factor DB1) [Source:UniProtKB/Swiss-Prot;Acc:Q14119] 521 1 QKQQQQQQQQQQQQQQQQQQ 20 95 18 0.9 335 354 64 LKTHGQSQSINCNTCKQGISKTCMSEETSN HVTSWPGKQVETLRLWEEAVKARKKEAANL GO:0003677:DNA binding;GO:0003704:specific RNA polymerase II transcription factor activity;GO:0008270:zinc ion binding;GO:0046872:metal ion binding; GO:0001525:angiogenesis;GO:0001885:endothelial cell development;GO:0006350:transcription;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0006968:cellular defense response; GO:0005622:intracellular;GO:0005634:nucleus; --- >prot|ENSP00000326391|cod|ENST00000314018|gene|ENSG00000180535|ann|Class B basic helix-loop-helix protein 8 (bHLHB8)(Muscle, intestine and stomach expression 1)(MIST-1) [Source:UniProtKB/Swiss-Prot;Acc:Q7RTS1] 189 1 QHYQQQQQ 8 75 5 0.625 151 158 79 KNYIKSLTATILTMSSSRLPGLEGPGPKLY VAGGALGATEAQPQGHLQRYSTQIHSFREG GO:0003677:DNA binding;GO:0005515:protein binding;GO:0030528:transcription regulator activity;GO:0042803:protein homodimerization activity;GO:0003700:sequence-specific DNA binding transcription factor activity; GO:0006355:regulation of transcription, DNA-dependent;GO:0006851:mitochondrial calcium ion transport;GO:0007030:Golgi organization;GO:0007186:G-protein coupled receptor protein signaling pathway;GO:0007267:cell-cell signaling;GO:0019722:calcium-mediated signaling;GO:0042593:glucose homeostasis;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0048312:intracellular distribution of mitochondria;GO:0048469:cell maturation;GO:0045449:regulation of transcription; GO:0005634:nucleus; --- >prot|ENSP00000378830|cod|ENST00000395443|gene|ENSG00000198218|ann|Glutamine-rich protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q2TAL8] 776 1 QQQQQQLQ 8 87.5 6 0.75 435 442 56 TYQNTAQTVHIWDPQQQPQQQTPQEQTPPP VTCSAQTVQVAEVEPQSQPQPSPELLLPNS GO:0005515:protein binding; --- --- --- >prot|ENSP00000354689|cod|ENST00000362021|gene|ENSG00000165915|ann|Zinc transporter ZIP13 (Zrt- and Irt-like protein 13)(ZIP-13)(Solute carrier family 39 member 13)(LIV-1 subfamily of ZIP zinc transporter 9)(LZT-Hs9) [Source:UniProtKB/Swiss-Prot;Acc:Q96H72] 371 1 QSLQQQQQ 8 75 5 0.625 143 150 38 ALGGLLGNVFLHLLPEAWAYTCSASPGGEG LGLWVIAGILTFLALEKMFLDSKEEGTSQA GO:0008270:zinc ion binding;GO:0046873:metal ion transmembrane transporter activity;GO:0015450:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; GO:0006811:ion transport;GO:0006829:zinc ion transport;GO:0030001:metal ion transport;GO:0015031:protein transport; GO:0016020:membrane;GO:0016021:integral to membrane; 612350: SPONDYLOCHEIRODYSPLASIA, EHLERS-DANLOS SYNDROME-LIKE; >prot|ENSP00000332706|cod|ENST00000331327|gene|ENSG00000185129|ann|Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha) [Source:UniProtKB/Swiss-Prot;Acc:Q00577] 322 1 QLHQQQQQQQ 10 80 7 0.7 294 303 91 WAKFGHTFCKYSEEMKKIQEKQREKRAACE EETAAATLLLQGEEEGEED GO:0003691:double-stranded telomeric DNA binding;GO:0003697:single-stranded DNA binding;GO:0003705:RNA polymerase II transcription factor activity, enhancer binding;GO:0008134:transcription factor binding;GO:0046332:SMAD binding;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0005515:protein binding;GO:0003677:DNA binding;GO:0003690:double-stranded DNA binding; GO:0006268:DNA unwinding involved in replication;GO:0006270:DNA-dependent DNA replication initiation;GO:0006350:transcription;GO:0007399:nervous system development;GO:0008284:positive regulation of cell proliferation;GO:0045892:negative regulation of transcription, DNA-dependent; GO:0000784:nuclear chromosome, telomeric region;GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0005662:DNA replication factor A complex; --- >prot|ENSP00000363215|cod|ENST00000374102|gene|ENSG00000184634|ann|Mediator of RNA polymerase II transcription subunit 12 (Mediator complex subunit 12)(Thyroid hormone receptor-associated protein complex 230 kDa component)(Trap230)(Activator-recruited cofactor 240 kDa component)(ARC240)(CAG repeat protein 45)(OPA-containing protein)(Trinucleotide repeat-containing gene 11 protein) [Source:UniProtKB/Swiss-Prot;Acc:Q93074] 2176 1 QQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQ 100 79 26 0.26 2050 2149 94 LQQTPMISTMTPMSAQGVQAGVRSTAILPE TAALVRQLQQQLSNTQPQPSTNIFGRY GO:0004872:receptor activity;GO:0016455:RNA polymerase II transcription mediator activity;GO:0019904:protein domain specific binding;GO:0030374:ligand-dependent nuclear receptor transcription coactivator activity;GO:0042809:vitamin D receptor binding;GO:0046966:thyroid hormone receptor binding; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0006367:transcription initiation from RNA polymerase II promoter;GO:0030521:androgen receptor signaling pathway;GO:0045944:positive regulation of transcription from RNA polymerase II promoter; GO:0000119---GO:0005634:nucleus;GO:0005730:nucleolus;GO:0005813:centrosome; 309520: LUJAN-FRYNS SYNDROME;305450: OPITZ-KAVEGGIA SYNDROME; >prot|ENSP00000269197|cod|ENST00000269197|gene|ENSG00000141431|ann|Putative Polycomb group protein ASXL3 (Additional sex combs-like protein 3) [Source:UniProtKB/Swiss-Prot;Acc:Q9C0F0] 2248 1 QVQQQQQ 7 85.7142857142857 5 0.714285714285714 2143 2149 95 KAFALKSADFSSYLLSEPQKPFTQLAAQKM LCGNYPTIHFGSTSFKRAASAIEKSIGILG GO:0008270:zinc ion binding;GO:0046872:metal ion binding; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent; GO:0005634:nucleus; --- >prot|ENSP00000371629|cod|ENST00000382194|gene|ENSG00000080503|ann|Probable global transcription activator SNF2L2 (EC 3.6.1.-)(ATP-dependent helicase SMARCA2)(SNF2-alpha)(SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2)(hBRM) [Source:UniProtKB/Swiss-Prot;Acc:P51531] 1572 1 QQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQ 38 86.8421052631579 23 0.605263157894737 216 253 13 ILAYKMLARGQPLPETLQLAVQGKRTLPGL PALVNYNRPSGPGPELSGPSTPQKLPVPAP GO:0000166:nucleotide binding;GO:0003677:DNA binding;GO:0003713:transcription coactivator activity;GO:0004386:helicase activity;GO:0005515:protein binding;GO:0005524:ATP binding;GO:0016787:hydrolase activity;GO:0016818:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;GO:0003676:nucleic acid binding; GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0045449:regulation of transcription; GO:0005634:nucleus;GO:0005654:nucleoplasm;GO:0016514:SWI/SNF complex; --- >prot|ENSP00000288462|cod|ENST00000288462|gene|ENSG00000157653|ann|Uncharacterized protein C9orf43 [Source:UniProtKB/Swiss-Prot;Acc:Q8TAL5] 461 1 QQQRQQQQQQQQ 12 91.6666666666667 8 0.666666666666667 293 304 63 IHRLTLERPALRYPERLKKLHNLKTEGYRK KKVKTPIKKQEAKKKAKSDPGIQSTSHKHP --- --- --- --- >prot|ENSP00000225768|cod|ENST00000225768|gene|ENSG00000178607|ann|Serine/threonine-protein kinase/endoribonuclease IRE1 Precursor (Inositol-requiring protein 1)(hIRE1p)(Ire1-alpha)(IRE1a)(Endoplasmic reticulum-to-nucleus signaling 1) [Includes Serine/threonine-protein kinase(EC 2.7.11.1);Endoribonuclease(EC 3.1.26.-)] [Source:UniProtKB/Swiss-Prot;Acc:O75460] 976 1 QLLQQQQQQ 9 77.7777777777778 6 0.666666666666667 486 494 49 WVAFIITYPLSMHQQQQLQHQQFQKELEKI LPFHPPGDTAQDGELLDTSGPYSESSGTSS GO:0000166:nucleotide binding;GO:0000287:magnesium ion binding;GO:0004674:protein serine/threonine kinase activity;GO:0005515:protein binding;GO:0005524:ATP binding;GO:0016740:transferase activity;GO:0016787:hydrolase activity;GO:0016891:endoribonuclease activity, producing 5'-phosphomonoesters;GO:0004672:protein kinase activity;GO:0004713:protein tyrosine kinase activity;GO:0004521:endoribonuclease activity; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0006397:mRNA processing;GO:0006464:protein modification process;GO:0006468:protein amino acid phosphorylation;GO:0006915:apoptosis;GO:0006917:induction of apoptosis;GO:0006986:response to unfolded protein;GO:0006987:activation of signaling protein activity involved in unfolded protein response;GO:0007050:cell cycle arrest;GO:0046777:protein amino acid autophosphorylation; GO:0016020:membrane;GO:0016021:integral to membrane;GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0030176:integral to endoplasmic reticulum membrane; --- >prot|ENSP00000384090|cod|ENST00000403100|gene|ENSG00000128573|ann|Forkhead box protein P2 (CAG repeat protein 44)(Trinucleotide repeat-containing gene 10 protein) [Source:UniProtKB/Swiss-Prot;Acc:O15409] 382 1 QQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQ 77 75.3246753246753 40 0.519480519480519 58 134 15 ALLQQQQAVMLQQDFLDSGLENFRAALEKN LAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ GO:0008270:zinc ion binding; --- GO:0005622:intracellular; --- >prot|ENSP00000352872|cod|ENST00000359819|gene|ENSG00000066427|ann|ataxin 3 isoform 1 [Source:RefSeq peptide;Acc:NP_004984] 373 1 QQQKQQQQQQQQQQ 14 92.8571428571429 10 0.714285714285714 304 317 81 TNLTSEELRKRREAYFEKLRLKKKEKENFI GDLSGQSSHPCERPATSSGALGSDLGDAMS --- --- --- --- >prot|ENSP00000290607|cod|ENST00000290607|gene|ENSG00000159433|ann|StAR-related lipid transfer protein 9 (START domain-containing protein 9)(StARD9) [Source:UniProtKB/Swiss-Prot;Acc:Q9P2P6] 4614 1 QQQQQEDQ 8 75 5 0.625 656 663 14 ELEFDQAWISQQIKENQQCLLREETWLASL VAEKELEASVALDAWLQTDPEIQPSPFVQS GO:0003777:microtubule motor activity;GO:0005524:ATP binding; GO:0007018:microtubule-based movement; GO:0005875:microtubule associated complex; --- >prot|ENSP00000376470|cod|ENST00000392706|gene|ENSG00000159409|ann|CUG-BP- and ETR-3-like factor 3 (CELF-3)(Bruno-like protein 1)(RNA-binding protein BRUNOL-1)(ELAV-type RNA-binding protein 1)(ETR-1)(Trinucleotide repeat-containing gene 4 protein)(Expanded repeat domain protein CAG/CTG 4)(CAG repeat protein 4) [Source:UniProtKB/Swiss-Prot;Acc:Q5SZQ8] 260 1 QQPPPPPQQQQQQQQQQQQQQQ 22 77.2727272727273 15 0.681818181818182 147 168 56 PNGVHPYPAAYPAAYSLVAPAFPQPPALVA REGPDGCNIFIYHLPQEFTDSEILQMFVPF GO:0003676:nucleic acid binding;GO:0003723:RNA binding; GO:0030317:sperm motility;GO:0007283:spermatogenesis; GO:0005634:nucleus;GO:0005737:cytoplasm; --- >prot|ENSP00000362963|cod|ENST00000373856|gene|ENSG00000147140|ann|Non-POU domain-containing octamer-binding protein (NonO protein)(54 kDa nuclear RNA- and DNA-binding protein)(p54(nrb))(p54nrb)(55 kDa nuclear protein)(NMT55)(DNA-binding p52/p100 complex, 52 kDa subunit) [Source:UniProtKB/Swiss-Prot;Acc:Q15233] 471 1 QQQHHQQQQQQ 11 81.8181818181818 6 0.545454545454545 25 35 5 MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQ PPPPPIPANGQQASSQNEGLTIDLKNFRKP GO:0000166:nucleotide binding;GO:0003677:DNA binding;GO:0003723:RNA binding;GO:0042802:identical protein binding;GO:0003676:nucleic acid binding; GO:0006281:DNA repair;GO:0006310:DNA recombination;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0006397:mRNA processing;GO:0006974:response to DNA damage stimulus;GO:0008380:RNA splicing; GO:0005634:nucleus; --- >prot|ENSP00000384983|cod|ENST00000406993|gene|ENSG00000155816|ann|Formin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9NZ56] 1865 1 QQQQQQQLQLQLQQQQQQQQLQ 22 81.8181818181818 8 0.363636363636364 349 370 18 SSGSDTDIYSFHSATEQEDLLSDIQQAIRL GAEEPAAPPTAVSPQPGAFLGLDRFLLGPS GO:0003674:molecular_function;GO:0003779:actin binding;GO:0005529:sugar binding; GO:0007132:meiotic metaphase I;GO:0007275:multicellular organismal development;GO:0016043:cellular component organization;GO:0016344:meiotic chromosome movement towards spindle pole;GO:0030036:actin cytoskeleton organization;GO:0040038:polar body extrusion after meiotic divisions;GO:0048477:oogenesis;GO:0051295:establishment of meiotic spindle localization;GO:0007242---GO:0007186:G-protein coupled receptor protein signaling pathway; GO:0016021:integral to membrane;GO:0005575:cellular_component; --- >prot|ENSP00000377634|cod|ENST00000394071|gene|ENSG00000156030|ann|Uncharacterized protein C14orf43 [Source:UniProtKB/Swiss-Prot;Acc:Q6PJG2] 1045 1 QKQQQQQQPQQQQQQQQ 17 88.2352941176471 8 0.470588235294118 246 262 23 PFQLAFGHQVNRQVFRQGPPPPNPVAAFPP AALPQMPLFENFYSMPQQPSQQPQDFGLQP GO:0003677:DNA binding;GO:0045735:nutrient reservoir activity; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent; GO:0005634:nucleus; --- >prot|ENSP00000359428|cod|ENST00000370401|gene|ENSG00000013619|ann|Mastermind-like domain-containing protein 1 (Protein CG1)(F18) [Source:UniProtKB/Swiss-Prot;Acc:Q13495] 774 2 QQQQQQQQQQQ 11 100 11 1 492 502 63 KLSSPGLPQQSFTPQCSLIRSLTPTSNLLS ANVIFKPISSNSSKTLSMIMQQGMASSSPG GO:0003674:molecular_function; GO:0008150:biological_process; GO:0005575:cellular_component; 300758: HYPOSPADIAS 2, X-LINKED;300633: HYPOSPADIAS 1, X-LINKED; >prot|ENSP00000359428|cod|ENST00000370401|gene|ENSG00000013619|ann|Mastermind-like domain-containing protein 1 (Protein CG1)(F18) [Source:UniProtKB/Swiss-Prot;Acc:Q13495] 774 2 QLQQQQQQQQQQ 12 91.6666666666667 10 0.833333333333333 595 606 76 RQPSLLHYLQQPTPTQASSATASSTATATL PDHSSFLLQQMMQQPQRFQRSVASDSMPAL GO:0003674:molecular_function; GO:0008150:biological_process; GO:0005575:cellular_component; 300758: HYPOSPADIAS 2, X-LINKED;300633: HYPOSPADIAS 1, X-LINKED; >prot|ENSP00000273432|cod|ENST00000273432|gene|ENSG00000144893|ann|Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein)(Thyroid hormone receptor-associated-like protein)(Trinucleotide repeat-containing gene 11 protein-like) [Source:UniProtKB/Swiss-Prot;Acc:Q86YW9] 1809 2 QQQQQQ 6 100 6 1 1747 1752 96 MLQRRSGAMMQPPSLHAITSQQQLIQMKLL RLLRQAQTRPFQQFPRQGLQQTQQQQQTAA GO:0030528:transcription regulator activity; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent; GO:0005634:nucleus; --- >prot|ENSP00000273432|cod|ENST00000273432|gene|ENSG00000144893|ann|Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein)(Thyroid hormone receptor-associated-like protein)(Trinucleotide repeat-containing gene 11 protein-like) [Source:UniProtKB/Swiss-Prot;Acc:Q86YW9] 1809 2 QQTQQQQQ 8 87.5 5 0.625 1772 1779 97 QMKLLQQQQQQRLLRQAQTRPFQQFPRQGL TAALVRQLQKQLSSNQPQQGVTPYGHPSHF GO:0030528:transcription regulator activity; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent; GO:0005634:nucleus; --- >prot|ENSP00000363267|cod|ENST00000374152|gene|ENSG00000117713|ann|AT-rich interactive domain-containing protein 1A (ARID domain-containing protein 1A)(SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1)(SWI-SNF complex protein p270)(B120)(SWI-like protein)(Osa homolog 1)(hOSA1)(hELD)(BRG1-associated factor 250)(BAF250)(BRG1-associated factor 250a)(BAF250A) [Source:UniProtKB/Swiss-Prot;Acc:O14497] 1685 2 QQQQQQQQ 8 100 8 1 944 951 56 EGNMSTGAPQPNLMPSNPDSGMYSPSRYPP RHDSYGNQFSTQGTPSGSPFPSQQTTMYQQ GO:0003677:DNA binding;GO:0005515:protein binding;GO:0016563:transcription activator activity;GO:0004879:ligand-dependent nuclear receptor activity;GO:0005488:binding; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0016568:chromatin modification;GO:0030520:estrogen receptor signaling pathway;GO:0030521:androgen receptor signaling pathway;GO:0042766:nucleosome mobilization;GO:0042921:glucocorticoid receptor signaling pathway;GO:0048096:chromatin-mediated maintenance of transcription;GO:0006325:chromatin organization; GO:0005622:intracellular;GO:0005634:nucleus;GO:0016514:SWI/SNF complex; --- >prot|ENSP00000363267|cod|ENST00000374152|gene|ENSG00000117713|ann|AT-rich interactive domain-containing protein 1A (ARID domain-containing protein 1A)(SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1)(SWI-SNF complex protein p270)(B120)(SWI-like protein)(Osa homolog 1)(hOSA1)(hELD)(BRG1-associated factor 250)(BAF250)(BRG1-associated factor 250a)(BAF250A) [Source:UniProtKB/Swiss-Prot;Acc:O14497] 1685 2 QQQQQ 5 100 5 1 980 984 58 QQRHDSYGNQFSTQGTPSGSPFPSQQTTMY VSSPAPLPRPMENRTSPSKSPFLHSGMKMQ GO:0003677:DNA binding;GO:0005515:protein binding;GO:0016563:transcription activator activity;GO:0004879:ligand-dependent nuclear receptor activity;GO:0005488:binding; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0016568:chromatin modification;GO:0030520:estrogen receptor signaling pathway;GO:0030521:androgen receptor signaling pathway;GO:0042766:nucleosome mobilization;GO:0042921:glucocorticoid receptor signaling pathway;GO:0048096:chromatin-mediated maintenance of transcription;GO:0006325:chromatin organization; GO:0005622:intracellular;GO:0005634:nucleus;GO:0016514:SWI/SNF complex; --- >prot|ENSP00000354896|cod|ENST00000361719|gene|ENSG00000152822|ann|T-cell surface glycoprotein CD3 zeta chain Precursor (T-cell receptor T3 zeta chain)(CD247 antigen) [Source:UniProtKB/Swiss-Prot;Acc:P20963] 1194 1 QQQQQ 5 100 5 1 1018 1022 85 TPPLPSHLTAEETPLFLAEPALPKGLPPPL PPPQQKSLMDQLQGVVSNFSTAIPDFHAVL GO:0004930:G-protein coupled receptor activity;GO:0004965:GABA-B receptor activity; GO:0007186:G-protein coupled receptor protein signaling pathway; GO:0016021:integral to membrane; --- >prot|ENSP00000372434|cod|ENST00000382974|gene|ENSG00000099917|ann|Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15)(Positive cofactor 2 glutamine/Q-rich-associated protein)(PC2 glutamine/Q-rich-associated protein)(TPA-inducible gene 1 protein)(TIG-1)(Activator-recruited cofactor 105 kDa component)(ARC105)(CTG repeat protein 7a)(Trinucleotide repeat-containing gene 7 protein) [Source:UniProtKB/Swiss-Prot;Acc:Q96RN5] 677 2 QQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQ 58 75.8620689655172 11 0.189655172413793 90 147 13 ARLIIHFRDIHNKKSQASVSAQLQLQQVAL HLIKLHHQNQQQIQQQQQQLQRIAQLQLQQ GO:0005199:structural constituent of cell wall; --- --- --- >prot|ENSP00000007660|cod|ENST00000007660|gene|ENSG00000006377|ann|Homeobox protein DLX-6 [Source:UniProtKB/Swiss-Prot;Acc:P56179] 265 1 QQQQQQ 6 100 6 1 26 31 9 MMTMTTMADGLEGQDSSKSAFMEFGQQQQQ HSPAMAGAHYPLHCLHSAAAAAAAGSHHHH GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0043565:sequence-specific DNA binding;GO:0030528:transcription regulator activity; GO:0001501:skeletal system development;GO:0006355:regulation of transcription, DNA-dependent;GO:0007275:multicellular organismal development;GO:0007399:nervous system development;GO:0030326:embryonic limb morphogenesis;GO:0030855:epithelial cell differentiation;GO:0042472:inner ear morphogenesis;GO:0048646:anatomical structure formation involved in morphogenesis;GO:0050679:positive regulation of epithelial cell proliferation; GO:0005634:nucleus; --- >prot|ENSP00000356451|cod|ENST00000367481|gene|ENSG00000164506|ann|Syntaxin-binding protein 5 (Tomosyn-1)(Lethal(2) giant larvae protein homolog 3) [Source:UniProtKB/Swiss-Prot;Acc:Q5T5C0] 1115 1 QQQQQQ 6 100 6 1 22 27 1 MRKFNIRKVLDGLTAGSSSASQQQQQQHPP HPPGNREPEIQETLQSEHFQLCKTVRHGFP --- GO:0016192:vesicle-mediated transport; GO:0016021:integral to membrane; --- >prot|ENSP00000266671|cod|ENST00000266671|gene|ENSG00000139289|ann|Pleckstrin homology-like domain family A member 1 (T-cell death-associated gene 51 protein)(Apoptosis-associated nuclear protein)(Proline- and histidine-rich protein)(Proline- and glutamine-rich protein)(PQ-rich protein) [Source:UniProtKB/Swiss-Prot;Acc:Q8WV24] 401 1 QLQHQQQQQQQQQQQQQQQPGQ 22 81.8181818181818 15 0.681818181818182 186 207 46 LEKRSDGLLQLWKKKCCILTEEGLLLIPPK GPAEPSQPSGPAVASLEPPVKLKELHFSNM GO:0005515:protein binding; GO:0006915:apoptosis;GO:0045210:FasL biosynthetic process; GO:0016020:membrane;GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0030659:cytoplasmic vesicle membrane;GO:0031410:cytoplasmic vesicle; --- >prot|ENSP00000272804|cod|ENST00000272804|gene|ENSG00000144369|ann|Protein FAM171B Precursor [Source:UniProtKB/Swiss-Prot;Acc:Q6P995] 427 1 QQQQQQQQQQQQQQKQ 16 93.75 14 0.875 43 58 10 LLGLAVVLLKARLVPAAARAELSRSDLSLI LEEAEEERTEVPGATSTLTVPVSVFMLKVQ GO:0003677:DNA binding; --- GO:0016020:membrane;GO:0016021:integral to membrane; --- >prot|ENSP00000346420|cod|ENST00000354436|gene|ENSG00000102908|ann|Nuclear factor of activated T-cells 5 (NF-AT5)(T-cell transcription factor NFAT5)(Tonicity-responsive enhancer-binding protein)(TonE-binding protein)(TonEBP) [Source:UniProtKB/Swiss-Prot;Acc:O94916] 1531 3 QQQQQ 5 100 5 1 739 743 48 TQFQTRETQSREILQSDGTVVNLSQLTEAS SPLQEQAQTLQQQISSNIFPSPNSVSQLQN GO:0003700:sequence-specific DNA binding transcription factor activity; GO:0045449:regulation of transcription;GO:0006355:regulation of transcription, DNA-dependent; GO:0005634:nucleus; --- >prot|ENSP00000346420|cod|ENST00000354436|gene|ENSG00000102908|ann|Nuclear factor of activated T-cells 5 (NF-AT5)(T-cell transcription factor NFAT5)(Tonicity-responsive enhancer-binding protein)(TonE-binding protein)(TonEBP) [Source:UniProtKB/Swiss-Prot;Acc:O94916] 1531 3 QQQQQQQQQQ 10 100 10 1 879 888 57 TEPTVHTRPDNLLPGRAESVHPQSENTLSN VMESSAAMVMEMQQSICQAAAQIQSELFPS GO:0003700:sequence-specific DNA binding transcription factor activity; GO:0045449:regulation of transcription;GO:0006355:regulation of transcription, DNA-dependent; GO:0005634:nucleus; --- >prot|ENSP00000346420|cod|ENST00000354436|gene|ENSG00000102908|ann|Nuclear factor of activated T-cells 5 (NF-AT5)(T-cell transcription factor NFAT5)(Tonicity-responsive enhancer-binding protein)(TonE-binding protein)(TonEBP) [Source:UniProtKB/Swiss-Prot;Acc:O94916] 1531 3 QSNSPSQEQQQQQQQQQQQQQQQQQ 25 76 17 0.68 1242 1266 81 QVALGSLPPNPMPQSQQGTMFQSQHSIVAM SILFSNQNTMATMASPKQPPPNMIFNPNQN GO:0003700:sequence-specific DNA binding transcription factor activity; GO:0045449:regulation of transcription;GO:0006355:regulation of transcription, DNA-dependent; GO:0005634:nucleus; --- >prot|ENSP00000320485|cod|ENST00000324856|gene|ENSG00000117713|ann|AT-rich interactive domain-containing protein 1A (ARID domain-containing protein 1A)(SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1)(SWI-SNF complex protein p270)(B120)(SWI-like protein)(Osa homolog 1)(hOSA1)(hELD)(BRG1-associated factor 250)(BAF250)(BRG1-associated factor 250a)(BAF250A) [Source:UniProtKB/Swiss-Prot;Acc:O14497] 2285 2 QQQQQ 5 100 5 1 1363 1367 59 QQRHDSYGNQFSTQGTPSGSPFPSQQTTMY NYKRPMDGTYGPPAKRHEGEMYSVPYSTGQ GO:0003677:DNA binding;GO:0005515:protein binding;GO:0016563:transcription activator activity;GO:0004879:ligand-dependent nuclear receptor activity;GO:0005488:binding; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0016568:chromatin modification;GO:0030520:estrogen receptor signaling pathway;GO:0030521:androgen receptor signaling pathway;GO:0042766:nucleosome mobilization;GO:0042921:glucocorticoid receptor signaling pathway;GO:0048096:chromatin-mediated maintenance of transcription;GO:0006325:chromatin organization; GO:0005622:intracellular;GO:0005634:nucleus;GO:0016514:SWI/SNF complex; --- >prot|ENSP00000307183|cod|ENST00000302327|gene|ENSG00000168556|ann|Inhibitor of growth protein 2 (p33ING2)(Inhibitor of growth 1-like protein)(ING1Lp)(p32) [Source:UniProtKB/Swiss-Prot;Acc:Q9H160] 280 1 QQQQQ 5 100 5 1 4 8 1 MLGQQQQQLYSSAALLTGERSRLLTCYVQD LYSSAALLTGERSRLLTCYVQDYLECVESL GO:0003677:DNA binding;GO:0003682:chromatin binding;GO:0005515:protein binding;GO:0008270:zinc ion binding;GO:0016563:transcription activator activity;GO:0046872:metal ion binding; GO:0006355:regulation of transcription, DNA-dependent;GO:0007165:signal transduction;GO:0016568:chromatin modification;GO:0040008:regulation of growth;GO:0045941:positive regulation of transcription; GO:0005634:nucleus;GO:0005694:chromosome;GO:0016602:CCAAT-binding factor complex; --- >prot|ENSP00000376967|cod|ENST00000393289|gene|ENSG00000066427|ann|ataxin 3 isoform 1 [Source:RefSeq peptide;Acc:NP_004984] 370 1 QKYIQQQKQQQQQQQQQQ 18 77.7777777777778 10 0.555555555555556 297 314 80 DMTQTSGTNLTSEELRKRREAYFEKVRLRL GDLSGQSSHPCERPATSSGALGSDLGDAMS --- --- --- --- >prot|ENSP00000384004|cod|ENST00000403058|gene|ENSG00000106536|ann|POU domain, class 6, transcription factor 2 (Retina-derived POU domain factor 1)(RPF-1) [Source:UniProtKB/Swiss-Prot;Acc:P78424] 683 1 QLQQLQLQLQQQQQQQQQQ 19 78.9473684210526 10 0.526315789473684 170 188 24 NIQGLVAAAAAGGIMTLPLQNLQATSSLNS PPPSTNQHPQPAPQAPSQSQQQPLQPTPPQ GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0043565:sequence-specific DNA binding;GO:0004890:GABA-A receptor activity;GO:0003677:DNA binding; GO:0006355:regulation of transcription, DNA-dependent;GO:0006821:chloride transport;GO:0007214:gamma-aminobutyric acid signaling pathway;GO:0007186:G-protein coupled receptor protein signaling pathway; GO:0016021:integral to membrane;GO:0005634:nucleus; 601583: WILMS TUMOR 5; >prot|ENSP00000251757|cod|ENST00000251757|gene|ENSG00000111752|ann|Polyhomeotic-like protein 1 (hPH1)(Early development regulatory protein 1) [Source:UniProtKB/Swiss-Prot;Acc:P78364] 1004 2 QQQQQ 5 100 5 1 381 385 37 MNLTRTATPAPSQTLISSATYTQIQPHSLI IHLQQKQVVIQQQIAIHHQQQFQHRQSQLL GO:0003677:DNA binding;GO:0005515:protein binding;GO:0008270:zinc ion binding;GO:0046872:metal ion binding; GO:0007275:multicellular organismal development; GO:0005634:nucleus;GO:0005730:nucleolus; --- >prot|ENSP00000251757|cod|ENST00000251757|gene|ENSG00000111752|ann|Polyhomeotic-like protein 1 (hPH1)(Early development regulatory protein 1) [Source:UniProtKB/Swiss-Prot;Acc:P78364] 1004 2 QLAQQQQQQQQQQQQQQQPQ 20 85 15 0.75 422 441 42 QVVIQQQIAIHHQQQFQHRQSQLLHTATHL ATTLTAPQPPQVPPTQQVPPSQSQQQAQTL GO:0003677:DNA binding;GO:0005515:protein binding;GO:0008270:zinc ion binding;GO:0046872:metal ion binding; GO:0007275:multicellular organismal development; GO:0005634:nucleus;GO:0005730:nucleolus; --- >prot|ENSP00000282388|cod|ENST00000282388|gene|ENSG00000152518|ann|Butyrate response factor 2 (Protein TIS11D)(EGF-response factor 2)(ERF-2) [Source:UniProtKB/Swiss-Prot;Acc:P47974] 494 1 QQQQQQQ 7 100 7 1 395 401 79 FGPELSSLITPLAIQTHNFAAVAAAAYYRS GLAPPAQPPAPPSATLPAGAAAPPSPPFSF GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0003723:RNA binding;GO:0008270:zinc ion binding;GO:0046872:metal ion binding;GO:0050825:ice binding;GO:0003676:nucleic acid binding; GO:0000288:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0008283:cell proliferation;GO:0043488:regulation of mRNA stability;GO:0042309:homoiothermy;GO:0050826:response to freezing; GO:0005634:nucleus;GO:0005737:cytoplasm; --- >prot|ENSP00000317053|cod|ENST00000325129|gene|ENSG00000102804|ann|TSC22 domain family protein 1 (Transforming growth factor beta-1-induced transcript 4 protein)(Regulatory protein TSC-22)(TGFB-stimulated clone 22 homolog)(Cerebral protein 2) [Source:UniProtKB/Swiss-Prot;Acc:Q15714] 1073 1 QQQQQQQQQQQQQPALQ 17 82.3529411764706 13 0.764705882352941 497 513 46 GSSVSSSVSTLSHYTESVGSGEMGAPTVVV GVTLQQMDFGSTGPQSIPAVSIPQSISQSQ GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0005515:protein binding; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0006366:transcription from RNA polymerase II promoter; GO:0005634:nucleus;GO:0005737:cytoplasm; --- >prot|ENSP00000253692|cod|ENST00000253692|gene|ENSG00000131374|ann|TBC1 domain family member 5 [Source:UniProtKB/Swiss-Prot;Acc:Q92609] 795 1 QQQQQQQ 7 100 7 1 509 515 64 GGPVPGGNSSSSSSVVIPTRTSAEAPSHHL RLMKSESMPVQLNKGLSSKNISSSPSVESL GO:0005096:GTPase activator activity;GO:0005097:Rab GTPase activator activity;GO:0005515:protein binding; GO:0032313:regulation of Rab GTPase activity; GO:0005622:intracellular; --- >prot|ENSP00000310966|cod|ENST00000309424|gene|ENSG00000117877|ann|DNA-directed RNA polymerase I subunit RPA34 (RNA polymerase I-associated factor PAF49)(Anti-sense to ERCC-1 protein)(ASE-1)(CD3-epsilon-associated protein)(CD3E-associated protein)(CAST)(A34.5) [Source:UniProtKB/Swiss-Prot;Acc:O15446] 510 1 QQQQQ 5 100 5 1 504 508 98 ETVPQEEMPGPPLNSESGEEAPTGRDKKRK PV GO:0003899:DNA-directed RNA polymerase activity;GO:0005515:protein binding;GO:0005524:ATP binding; GO:0006350:transcription;GO:0007169:transmembrane receptor protein tyrosine kinase signaling pathway;GO:0009303:rRNA transcription;GO:0006457:protein folding; GO:0000120:RNA polymerase I transcription factor complex;GO:0005634:nucleus;GO:0005730:nucleolus;GO:0005736:DNA-directed RNA polymerase I complex; --- >prot|ENSP00000367043|cod|ENST00000377812|gene|ENSG00000113722|ann|Homeobox protein CDX-1 (Caudal-type homeobox protein 1) [Source:UniProtKB/Swiss-Prot;Acc:P47902] 130 1 QQQQQPPQ 8 75 5 0.625 82 89 63 LAANLGLTERQVKIWFQNRRAKERKVNKKK PPMAHDITATPAGPSLGGLCPSNTSLLATS --- GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0009952:anterior/posterior pattern formation;GO:0007389:pattern specification process; --- --- >prot|ENSP00000268124|cod|ENST00000268124|gene|ENSG00000140521|ann|DNA polymerase subunit gamma-1 (EC 2.7.7.7)(Mitochondrial DNA polymerase catalytic subunit)(PolG-alpha) [Source:UniProtKB/Swiss-Prot;Acc:P54098] 1239 1 QRRRQQQQQQQQQQQQQPQQPQ 22 77.2727272727273 13 0.590909090909091 39 60 3 VAGATVGPGPVPAPGRWVSSSVPASDPSDG VLSSEGGQLRHNPLDIQMLSRGLHEQIFGQ GO:0000287:magnesium ion binding;GO:0002020:protease binding;GO:0003677:DNA binding;GO:0003887:DNA-directed DNA polymerase activity;GO:0004527:exonuclease activity;GO:0005515:protein binding;GO:0016740:transferase activity;GO:0016779:nucleotidyltransferase activity;GO:0003676:nucleic acid binding; GO:0006264:mitochondrial DNA replication;GO:0006287:base-excision repair, gap-filling;GO:0007568:aging;GO:0006260:DNA replication;GO:0006261:DNA-dependent DNA replication; GO:0005739:mitochondrion;GO:0005743:mitochondrial inner membrane;GO:0005760:gamma DNA polymerase complex;GO:0042645:mitochondrial nucleoid; 607459: SENSORY ATAXIC NEUROPATHY, DYSARTHRIA, AND OPHTHALMOPARESIS;603041: MITOCHONDRIAL NEUROGASTROINTESTINAL ENCEPHALOPATHY SYNDROME;258450: PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL DNA DELETIONS,;256000: LEIGH SYNDROME;203700: ALPERS DIFFUSE DEGENERATION OF CEREBRAL GRAY MATTER WITH HEPATIC CIRRHOSIS;157640: PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL DNA DELETIONS,; >prot|ENSP00000367923|cod|ENST00000378654|gene|ENSG00000136143|ann|Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial Precursor (EC 6.2.1.5)(ATP-specific succinyl-CoA synthetase subunit beta)(Succinyl-CoA synthetase beta-A chain)(SCS-betaA)(Renal carcinoma antigen NY-REN-39) [Source:UniProtKB/Swiss-Prot;Acc:Q9P2R7] 463 1 QVQQQQQ 7 85.7142857142857 5 0.714285714285714 44 50 9 ATLRNHRPRTAQRAAAQVLGSSGLFNNHGL RNLSLHEYMSMELLQEAGVSVPKGYVAKSP GO:0004775:succinate-CoA ligase (ADP-forming) activity;GO:0005515:protein binding;GO:0005524:ATP binding;GO:0016874:ligase activity;GO:0003824:catalytic activity; GO:0006099:tricarboxylic acid cycle;GO:0006781:succinyl-CoA pathway;GO:0008152:metabolic process; GO:0005739:mitochondrion; 612073: MITOCHONDRIAL DNA DEPLETION SYNDROME, ENCEPHALOMYOPATHIC FORM, WITH;609560: MITOCHONDRIAL DNA DEPLETION SYNDROME, MYOPATHIC FORM;251880: MITOCHONDRIAL DNA DEPLETION SYNDROME, HEPATOCEREBRAL FORM, AUTOSOMAL; >prot|ENSP00000339764|cod|ENST00000339711|gene|ENSG00000152784|ann|PR domain zinc finger protein 8 (PR domain-containing protein 8) [Source:UniProtKB/Swiss-Prot;Acc:Q9NQV8] 689 1 QQQQQQ 6 100 6 1 212 217 30 LHSADISPQDEQGGGVGTKDHGGGGGGGKD EAPLGPGPKFCKAGPLHHYPSPSPESSNPS GO:0003677:DNA binding;GO:0008270:zinc ion binding; GO:0006281:DNA repair;GO:0022008:neurogenesis; GO:0005622:intracellular; --- >prot|ENSP00000374213|cod|ENST00000389562|gene|ENSG00000183495|ann|E1A-binding protein p400 (EC 3.6.1.-)(p400 kDa SWI2/SNF2-related protein)(Domino homolog)(hDomino)(CAG repeat protein 32)(Trinucleotide repeat-containing gene 12 protein) [Source:UniProtKB/Swiss-Prot;Acc:Q96L91] 3122 1 QLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 33 90.9090909090909 29 0.878787878787879 2715 2747 86 VQTPARSLVPQVSQATGVQLPGKTITPAHF TTTTSQVQVPQIQGQAQSPAQIKAVGKLTP GO:0003677:DNA binding;GO:0005524:ATP binding;GO:0003676:nucleic acid binding;GO:0004386:helicase activity; --- --- --- >prot|ENSP00000377133|cod|ENST00000393495|gene|ENSG00000128573|ann|Forkhead box protein P2 (CAG repeat protein 44)(Trinucleotide repeat-containing gene 10 protein) [Source:UniProtKB/Swiss-Prot;Acc:O15409] 170 1 QQQQQQQQQQQQQQ 14 100 14 1 53 66 31 LSSQLDAGSRDGRSSGDTSSEVSTVELLHL LAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ GO:0008270:zinc ion binding; --- GO:0005622:intracellular; --- >prot|ENSP00000376631|cod|ENST00000392897|gene|ENSG00000018408|ann|WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif) [Source:UniProtKB/Swiss-Prot;Acc:Q9GZV5] 400 1 QQQQQQ 6 100 6 1 228 233 56 QMAPSTLSQQNHPTQNPPAGLMSMPNALTT KLRLQRIQMERERIRMRQEELMRQEAALCR GO:0003713:transcription coactivator activity;GO:0003714:transcription corepressor activity;GO:0005515:protein binding;GO:0030528:transcription regulator activity;GO:0042803:protein homodimerization activity; GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0001649:osteoblast differentiation;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0045599:negative regulation of fat cell differentiation;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0007160:cell-matrix adhesion;GO:0032835:glomerulus development;GO:0060271:cilium morphogenesis; GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0005667:transcription factor complex;GO:0005856:cytoskeleton; --- >prot|ENSP00000375942|cod|ENST00000392092|gene|ENSG00000112592|ann|TATA-box-binding protein (TATA-box factor)(TATA-binding factor)(TATA sequence-binding protein)(Transcription initiation factor TFIID TBP subunit) [Source:UniProtKB/Swiss-Prot;Acc:P20226] 339 1 QQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 41 97.5609756097561 38 0.926829268292683 55 95 16 IPIFSPMMPYGTGLTPQPIQNTNSLSILEE AVAAAAVQQSTSQQATQGTSGQAPQLFHSQ GO:0003677:DNA binding;GO:0003702:RNA polymerase II transcription factor activity; GO:0006355:regulation of transcription, DNA-dependent;GO:0006367:transcription initiation from RNA polymerase II promoter; GO:0005634:nucleus;GO:0005669:transcription factor TFIID complex; --- >prot|ENSP00000350934|cod|ENST00000358201|gene|ENSG00000177548|ann|Rab GTPase-binding effector protein 2 (Rabaptin-5beta) [Source:UniProtKB/Swiss-Prot;Acc:Q9H5N1] 569 1 QERQQQQQ 8 75 5 0.625 106 113 18 QRQCQEEVASLQAILKDSISSYEAQITALK DCEEKERELGRLKQLLSRAYPLDSLEKQME GO:0003824:catalytic activity;GO:0005096:GTPase activator activity;GO:0008083:growth factor activity; --- --- --- >prot|ENSP00000266744|cod|ENST00000266744|gene|ENSG00000139352|ann|Achaete-scute homolog 1 (HASH1) [Source:UniProtKB/Swiss-Prot;Acc:P50553] 236 1 QSAQQQQQQQQQQQQAPQ 18 77.7777777777778 12 0.666666666666667 48 65 20 PQPQQPFLPPAACFFATAAAAAAAAAAAAA LRPAADGQPSGGGHKSAPKQVKRQRSSSPE GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0005515:protein binding;GO:0043565:sequence-specific DNA binding;GO:0050825:ice binding;GO:0030528:transcription regulator activity; GO:0001764:neuron migration;GO:0006355:regulation of transcription, DNA-dependent;GO:0007389:pattern specification process;GO:0007399:nervous system development;GO:0007400:neuroblast fate determination;GO:0007405:neuroblast proliferation;GO:0014003:oligodendrocyte development;GO:0021527:spinal cord association neuron differentiation;GO:0021530:spinal cord oligodendrocyte cell fate specification;GO:0021779:oligodendrocyte cell fate commitment;GO:0021954:central nervous system neuron development;GO:0021987:cerebral cortex development;GO:0045747:positive regulation of Notch signaling pathway;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0060163:subpallium neuron fate commitment;GO:0060165:regulation of timing of subpallium neuron differentiation;GO:0060166:olfactory pit development;GO:0042309:homoiothermy;GO:0050826:response to freezing;GO:0045449:regulation of transcription;GO:0030154:cell differentiation;GO:0007219:Notch signaling pathway;GO:0048663:neuron fate commitment;GO:0030182:neuron differentiation;GO:0010468:regulation of gene expression;GO:0048666:neuron development;GO:0048709:oligodendrocyte differentiation;GO:0010001:glial cell differentiation;GO:0021529:spinal cord oligodendrocyte cell differentiation; GO:0005634:nucleus;GO:0043025:neuronal cell body; 209880: AUTONOMIC CONTROL, CONGENITAL FAILURE OF; >prot|ENSP00000262189|cod|ENST00000262189|gene|ENSG00000055609|ann|Histone-lysine N-methyltransferase MLL3 (EC 2.1.1.43)(Myeloid/lymphoid or mixed-lineage leukemia protein 3)(Homologous to ALR protein)(Lysine N-methyltransferase 2C) [Source:UniProtKB/Swiss-Prot;Acc:Q8NEZ4] 4911 2 QQQQQQQQFGSQ 12 75 8 0.666666666666667 1780 1791 36 EWKFRQQMRQKSKQQAKIEATQKLEQVKNE HLLVQSGSDTPSSGIQSPLTPQPGNGNMSP GO:0016820:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;GO:0003677:DNA binding;GO:0005515:protein binding;GO:0008270:zinc ion binding; GO:0015986:ATP synthesis coupled proton transport;GO:0007242--- GO:0005634:nucleus;GO:0033178:proton-transporting two-sector ATPase complex, catalytic domain; --- >prot|ENSP00000262189|cod|ENST00000262189|gene|ENSG00000055609|ann|Histone-lysine N-methyltransferase MLL3 (EC 2.1.1.43)(Myeloid/lymphoid or mixed-lineage leukemia protein 3)(Homologous to ALR protein)(Lysine N-methyltransferase 2C) [Source:UniProtKB/Swiss-Prot;Acc:Q8NEZ4] 4911 2 QQQQQ 5 100 5 1 2393 2397 48 GVTDTQNTVNMAQADTEKLRQRQKLREIIL KKIAGRQEKGSQDSPAVPHPGPLQHWQPEN GO:0016820:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;GO:0003677:DNA binding;GO:0005515:protein binding;GO:0008270:zinc ion binding; GO:0015986:ATP synthesis coupled proton transport;GO:0007242--- GO:0005634:nucleus;GO:0033178:proton-transporting two-sector ATPase complex, catalytic domain; --- >prot|ENSP00000229340|cod|ENST00000229340|gene|ENSG00000111737|ann|Ras-related protein Rab-35 (Rab-1C)(GTP-binding protein RAY) [Source:UniProtKB/Swiss-Prot;Acc:Q15286] 201 1 QQQQQQ 6 100 6 1 179 184 89 TSAKENVNVEEMFNCITELVLRAKKDNLAK NDVVKLTKNSKRKKRCC GO:0000166:nucleotide binding;GO:0003924:GTPase activity;GO:0005525:GTP binding;GO:0005546:phosphatidylinositol-4,5-bisphosphate binding;GO:0004871:signal transducer activity;GO:0019001:guanyl nucleotide binding;GO:0005515:protein binding;GO:0005524:ATP binding;GO:0008134:transcription factor binding;GO:0017111:nucleoside-triphosphatase activity; GO:0000910:cytokinesis;GO:0007264:small GTPase mediated signal transduction;GO:0008104:protein localization;GO:0015031:protein transport;GO:0016197:endosome transport;GO:0007186:G-protein coupled receptor protein signaling pathway;GO:0006886:intracellular protein transport;GO:0006913:nucleocytoplasmic transport;GO:0007165:signal transduction;GO:0006355:regulation of transcription, DNA-dependent; GO:0005886:plasma membrane;GO:0005622:intracellular;GO:0005905:coated pit;GO:0031253:cell projection membrane;GO:0042470:melanosome;GO:0045171:intercellular bridge;GO:0045334:clathrin-coated endocytic vesicle; --- >prot|ENSP00000320794|cod|ENST00000316407|gene|ENSG00000176542|ann|Basic helix-loop-helix domain-containing protein KIAA2018 [Source:UniProtKB/Swiss-Prot;Acc:Q68DE3] 2245 1 QQQQQQQQQQQQQQQQQAGQ 20 90 17 0.85 1462 1481 65 TQASQHLQALQQHVPAQGVSHLHSNHLYIK LRERHHLYQMQHHVPHAESSVHSQPHNVHQ GO:0003677:DNA binding;GO:0004571:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509:calcium ion binding;GO:0030528:transcription regulator activity; GO:0045449:regulation of transcription; GO:0016020:membrane;GO:0005634:nucleus; --- >prot|ENSP00000309482|cod|ENST00000308547|gene|ENSG00000173889|ann|Polyhomeotic-like protein 3 (Homolog of polyhomeotic 3)(hPH3)(Early development regulatory protein 3) [Source:UniProtKB/Swiss-Prot;Acc:Q8NDX5] 995 1 QQQQQQIQ 8 87.5 6 0.75 340 347 34 SPIQPHSLIKHQQIPLHSPPSKVSHHQLIL PITLQNSTQDPPPSQHCIPLQNHGLPPAPS GO:0003677:DNA binding;GO:0008270:zinc ion binding;GO:0046872:metal ion binding; GO:0007275:multicellular organismal development; GO:0005634:nucleus; --- >prot|ENSP00000329170|cod|ENST00000328345|gene|ENSG00000184486|ann|POU domain, class 3, transcription factor 2 (Nervous system-specific octamer-binding transcription factor N-Oct-3)(Brain-specific homeobox/POU domain protein 2)(Brain-2)(Protein Brn-2) [Source:UniProtKB/Swiss-Prot;Acc:P20265] 443 1 QQQHQQQQQQQQQQQQQQQQQQQQQ 25 96 21 0.84 125 149 28 TSPLGQPDIKPSVVVQQGGRGDELHGPGAL RPPHLVHHAANHHPGPGAWRSAAAAAHLPP GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0042802:identical protein binding;GO:0043565:sequence-specific DNA binding;GO:0003677:DNA binding;GO:0030528:transcription regulator activity; GO:0008284:positive regulation of cell proliferation;GO:0008544:epidermis development;GO:0014002:astrocyte development;GO:0021799:cerebral cortex radially oriented cell migration;GO:0021869:forebrain ventricular zone progenitor cell division;GO:0021979:hypothalamus cell differentiation;GO:0021985:neurohypophysis development;GO:0022011:myelination in peripheral nervous system;GO:0030182:neuron differentiation;GO:0040018:positive regulation of multicellular organism growth;GO:0045595:regulation of cell differentiation;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0050770:regulation of axonogenesis;GO:0006355:regulation of transcription, DNA-dependent;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0014044:Schwann cell development; GO:0005634:nucleus;GO:0005667:transcription factor complex; --- >prot|ENSP00000370938|cod|ENST00000381527|gene|ENSG00000132964|ann|Cell division protein kinase 8 (EC 2.7.11.22)(EC 2.7.11.23)(Cyclin-dependent kinase 8)(Mediator of RNA polymerase II transcription subunit CDK8)(Mediator complex subunit CDK8)(Protein kinase K35) [Source:UniProtKB/Swiss-Prot;Acc:P49336] 464 1 QQQQQ 5 100 5 1 373 377 80 SDVFAGCQIPYPKREFLTEEEPDDKGDKKN GNNHTNGTGHPGNQDSSHTQGPPLKKVRVV GO:0000166:nucleotide binding;GO:0004693:cyclin-dependent protein kinase activity;GO:0005515:protein binding;GO:0005524:ATP binding;GO:0008353:RNA polymerase II carboxy-terminal domain kinase activity;GO:0016740:transferase activity;GO:0004672:protein kinase activity;GO:0004713:protein tyrosine kinase activity;GO:0004674:protein serine/threonine kinase activity; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0006468:protein amino acid phosphorylation; GO:0000119---GO:0005634:nucleus; --- >prot|ENSP00000304956|cod|ENST00000302326|gene|ENSG00000169184|ann|Probable tumor suppressor protein MN1 [Source:UniProtKB/Swiss-Prot;Acc:Q10571] 1320 2 QPPQQQPQQQQQPQQQQQQ 19 78.9473684210526 6 0.315789473684211 291 309 22 AGRQVPGGAFPGASAMPRAAGMVGLSKMHA HGVFFERFSGARKMPVGLEPSVGSRHPLMQ GO:0003674:molecular_function; GO:0008150:biological_process;GO:0045786:negative regulation of cell cycle; GO:0005575:cellular_component;GO:0005634:nucleus; 607174: MENINGIOMA, FAMILIAL; >prot|ENSP00000304956|cod|ENST00000302326|gene|ENSG00000169184|ann|Probable tumor suppressor protein MN1 [Source:UniProtKB/Swiss-Prot;Acc:Q10571] 1320 2 QSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQ 33 90.9090909090909 28 0.848484848484849 520 552 39 AYPGLPGEFTPPVPDSFPSGPPLQHPAPDH NAALMIKQMASRNQQQRLRQPNLAQLGHPG GO:0003674:molecular_function; GO:0008150:biological_process;GO:0045786:negative regulation of cell cycle; GO:0005575:cellular_component;GO:0005634:nucleus; 607174: MENINGIOMA, FAMILIAL; >prot|ENSP00000347427|cod|ENST00000355280|gene|ENSG00000141503|ann|Misshapen-like kinase 1 (EC 2.7.11.1)(Mitogen-activated protein kinase kinase kinase kinase 6)(MAPK/ERK kinase kinase kinase 6)(MEK kinase kinase 6)(MEKKK 6)(GCK family kinase MiNK)(Misshapen/NIK-related kinase) [Source:UniProtKB/Swiss-Prot;Acc:Q8N4C8] 1332 2 QQQQLQQQQQ 10 90 5 0.5 371 380 27 SIMNVPGESTLRREFLRLQQENKSNSEALK RDPEAHIKHLLHQRQRRIEEQKEERRRVEE GO:0004672:protein kinase activity;GO:0005524:ATP binding;GO:0005083:small GTPase regulator activity;GO:0004713:protein tyrosine kinase activity;GO:0004674:protein serine/threonine kinase activity;GO:0008270:zinc ion binding; GO:0006468:protein amino acid phosphorylation;GO:0045060:negative thymic T cell selection; GO:0005622:intracellular; --- >prot|ENSP00000347427|cod|ENST00000355280|gene|ENSG00000141503|ann|Misshapen-like kinase 1 (EC 2.7.11.1)(Mitogen-activated protein kinase kinase kinase kinase 6)(MAPK/ERK kinase kinase kinase 6)(MEK kinase kinase 6)(MEKKK 6)(GCK family kinase MiNK)(Misshapen/NIK-related kinase) [Source:UniProtKB/Swiss-Prot;Acc:Q8N4C8] 1332 2 QQQQQQQQLQKQQQQQ 16 87.5 8 0.5 480 495 36 EYKRKQLEEQRQSERLQRQLQQEHAYLKSL LLPGDRKPLYHYGRGMNPADKPAWAREVEE GO:0004672:protein kinase activity;GO:0005524:ATP binding;GO:0005083:small GTPase regulator activity;GO:0004713:protein tyrosine kinase activity;GO:0004674:protein serine/threonine kinase activity;GO:0008270:zinc ion binding; GO:0006468:protein amino acid phosphorylation;GO:0045060:negative thymic T cell selection; GO:0005622:intracellular; --- >prot|ENSP00000379401|cod|ENST00000396094|gene|ENSG00000109205|ann|Odontogenic ameloblast-associated protein Precursor (Apin) [Source:UniProtKB/Swiss-Prot;Acc:A1E959] 279 1 QQQQQAQ 7 85.7142857142857 5 0.714285714285714 62 68 22 LLLNLNNGQLLPLQLQGPLNSWIPPFSGIL IPGLSQFSLSALDQFAGLLPNQIPLTGEAS --- GO:0001503:ossification;GO:0042475:odontogenesis of dentine-containing tooth; GO:0005576:extracellular region; --- >prot|ENSP00000363929|cod|ENST00000374796|gene|ENSG00000198646|ann|Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3)(Cancer-amplified transcriptional coactivator ASC-2)(Activating signal cointegrator 2)(ASC-2)(Peroxisome proliferator-activated receptor-interacting protein)(PPAR-interacting protein)(PRIP)(Nuclear receptor-activating protein, 250 kDa)(Nuclear receptor coactivator RAP250)(NRC RAP250)(Thyroid hormone receptor-binding protein) [Source:UniProtKB/Swiss-Prot;Acc:Q14686] 2063 1 QPQSQQQQQQQQQ 13 84.6153846153846 9 0.692307692307692 1020 1032 49 LMQHVAPPPQPPQQQPQPQLPQQQQPPPPS MMMMLMMQQDPKSVRLPVSQNVHPPRGPLN GO:0003682:chromatin binding;GO:0005515:protein binding;GO:0030331:estrogen receptor binding;GO:0030374:ligand-dependent nuclear receptor transcription coactivator activity;GO:0046965:retinoid X receptor binding;GO:0046966:thyroid hormone receptor binding; GO:0001701:in utero embryonic development;GO:0006260:DNA replication;GO:0006281:DNA repair;GO:0006310:DNA recombination;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0006367:transcription initiation from RNA polymerase II promoter;GO:0007420:brain development;GO:0007507:heart development;GO:0009725:response to hormone stimulus;GO:0030099:myeloid cell differentiation;GO:0030520:estrogen receptor signaling pathway;GO:0042921:glucocorticoid receptor signaling pathway;GO:0045944:positive regulation of transcription from RNA polymerase II promoter; GO:0005634:nucleus;GO:0005667:transcription factor complex; --- >prot|ENSP00000284049|cod|ENST00000284049|gene|ENSG00000153922|ann|Chromodomain-helicase-DNA-binding protein 1 (CHD-1)(EC 3.6.1.-)(ATP-dependent helicase CHD1) [Source:UniProtKB/Swiss-Prot;Acc:O14646] 1710 1 QQQQQQQQQHQ 11 90.9090909090909 9 0.818181818181818 105 115 6 QAKPPKVDGAEFWKSSPSILAVQRSAILKK ASSNSGSEEDSSSSEDSDDSSSEVKRKKHK GO:0000166:nucleotide binding;GO:0003677:DNA binding;GO:0003682:chromatin binding;GO:0004003:ATP-dependent DNA helicase activity;GO:0004386:helicase activity;GO:0005524:ATP binding;GO:0016787:hydrolase activity;GO:0003676:nucleic acid binding; GO:0006333:chromatin assembly or disassembly;GO:0006338:chromatin remodeling;GO:0006357:regulation of transcription from RNA polymerase II promoter; GO:0000785:chromatin;GO:0005634:nucleus; --- >prot|ENSP00000263377|cod|ENST00000263377|gene|ENSG00000141867|ann|Bromodomain-containing protein 4 (HUNK1 protein) [Source:UniProtKB/Swiss-Prot;Acc:O60885] 1362 2 QQQQQ 5 100 5 1 771 775 56 HHHQQMQQAPAPVPQQPPPPPQQPPPPPPP PPPPPPPPSMPQQAAPAMKSSPPPFIATQV GO:0005515:protein binding;GO:0003677:DNA binding;GO:0005198:structural molecule activity; GO:0007186:G-protein coupled receptor protein signaling pathway;GO:0007155:cell adhesion;GO:0006468:protein amino acid phosphorylation;GO:0043388:positive regulation of DNA binding; GO:0000785:chromatin;GO:0016021:integral to membrane;GO:0005634:nucleus;GO:0015629:actin cytoskeleton; --- >prot|ENSP00000263377|cod|ENST00000263377|gene|ENSG00000141867|ann|Bromodomain-containing protein 4 (HUNK1 protein) [Source:UniProtKB/Swiss-Prot;Acc:O60885] 1362 2 QEQQQQQRQEQQQQQQQQ 18 83.3333333333333 8 0.444444444444444 1283 1300 94 ERLRQERMRSREDEDALEQARRAHEEARRR AAAVAAAATPQAQSSQPQSMLDQQRELARK GO:0005515:protein binding;GO:0003677:DNA binding;GO:0005198:structural molecule activity; GO:0007186:G-protein coupled receptor protein signaling pathway;GO:0007155:cell adhesion;GO:0006468:protein amino acid phosphorylation;GO:0043388:positive regulation of DNA binding; GO:0000785:chromatin;GO:0016021:integral to membrane;GO:0005634:nucleus;GO:0015629:actin cytoskeleton; --- >prot|ENSP00000381913|cod|ENST00000398940|gene|ENSG00000196782|ann|Mastermind-like protein 3 (Mam-3) [Source:UniProtKB/Swiss-Prot;Acc:Q96JK9] 276 2 QQKQQQQQQQQQQQQQQHSNQ 21 80.9523809523809 14 0.666666666666667 22 42 7 MSPAEQLKQMAAQQQQRAKLMQQKQQQQQQ TSNWSPLGPPSSPYGAAFTAEKPNSPMMYP GO:0003677:DNA binding;GO:0004879:ligand-dependent nuclear receptor activity; GO:0006355:regulation of transcription, DNA-dependent; GO:0005634:nucleus; --- >prot|ENSP00000385169|cod|ENST00000403821|gene|ENSG00000179912|ann|R3H domain-containing protein 2 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y2K5] 1042 1 QQQQQQQQQQ 10 100 10 1 436 445 41 SRPGMALGAPEVCNQVTSSQSVRGLLPCTA LPALPPTPQQQPPLNNHMISQPVPALQPSP GO:0003676:nucleic acid binding;GO:0045735:nutrient reservoir activity; --- --- --- >prot|ENSP00000377144|cod|ENST00000393508|gene|ENSG00000130733|ann|Protein YIPF2 (YIP1 family member 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9BWQ6] 316 1 QEQQQQQQ 8 87.5 6 0.75 67 74 21 QGHVAVAVGSGGSYGAEDEVEEESDKAALL PGFWTFSYYQSFFDVDTSQVLDRIKGSLLP --- --- GO:0016020:membrane;GO:0016021:integral to membrane;GO:0030133:transport vesicle; --- >prot|ENSP00000379306|cod|ENST00000395982|gene|ENSG00000141052|ann|Myocardin [Source:UniProtKB/Swiss-Prot;Acc:Q8IZQ8] 662 1 QQQQQQQ 7 100 7 1 23 29 3 MDSAYARLLQQQQLFLQLQILSQQQQQQQH HRFSYLGMHQAQLKEPNEQMVRNPNSSSTP GO:0003676:nucleic acid binding; --- --- --- >prot|ENSP00000343535|cod|ENST00000344836|gene|ENSG00000187555|ann|Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15)(Ubiquitin thioesterase 7)(Ubiquitin-specific-processing protease 7)(Deubiquitinating enzyme 7)(Herpesvirus-associated ubiquitin-specific protease) [Source:UniProtKB/Swiss-Prot;Acc:Q93009] 1102 1 QQQQQQQ 7 100 7 1 4 10 0 MNHQQQQQQQKAGEQQLSEPEDMEMEAGDT KAGEQQLSEPEDMEMEAGDTDDPPRITQNP GO:0004197:cysteine-type endopeptidase activity;GO:0004221:ubiquitin thiolesterase activity;GO:0004843:ubiquitin-specific protease activity;GO:0008022:protein C-terminus binding;GO:0008233:peptidase activity; GO:0006511:ubiquitin-dependent protein catabolic process;GO:0016579:protein deubiquitination;GO:0044419:interspecies interaction between organisms; GO:0005634:nucleus; --- >prot|ENSP00000383452|cod|ENST00000400609|gene|ENSG00000206490|ann|ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50)(TNF-alpha-stimulated ABC protein) [Source:UniProtKB/Swiss-Prot;Acc:Q8NE71] 238 1 QQQQQQQQQQ 10 100 10 1 64 73 26 DKKIKKTFFEELAVEDKQAGEEEKVLKEKE KKKRDTRKGRRKKDVDDDGEEKELMERLKK GO:0000166:nucleotide binding;GO:0005524:ATP binding;GO:0008135:translation factor activity, nucleic acid binding;GO:0016887:ATPase activity;GO:0042626:ATPase activity, coupled to transmembrane movement of substances;GO:0004176:ATP-dependent peptidase activity;GO:0004252:serine-type endopeptidase activity;GO:0017111:nucleoside-triphosphatase activity; GO:0006412:translation;GO:0006954:inflammatory response;GO:0006508:proteolysis; --- --- >prot|ENSP00000382150|cod|ENST00000399199|gene|ENSG00000146112|ann|Phostensin (Protein phosphatase 1 F-actin cytoskeleton-targeting subunit) [Source:UniProtKB/Swiss-Prot;Acc:Q6NYC8] 613 1 QERQQQQQQQQ 11 81.8181818181818 8 0.727272727272727 93 103 15 GTVEAGPPDPDESAVLLEAIGPVHQNRFIR RSEELLAERKPGPLEARERRPSPGEMRDQS GO:0003779:actin binding; --- GO:0005737:cytoplasm;GO:0005856:cytoskeleton; --- >prot|ENSP00000355870|cod|ENST00000366903|gene|ENSG00000136630|ann|H2.0-like homeobox protein (Homeobox protein HLX1)(Homeobox protein HB24) [Source:UniProtKB/Swiss-Prot;Acc:Q14774] 488 1 QQQQQQQQPQQQQ 13 92.3076923076923 8 0.615384615384615 125 137 25 PTPVVAPSEVPAGFPQRLSPLSAAYHHHHP PPPPPRAGALQPPASGTRVVPNPHHSGSAP GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0043565:sequence-specific DNA binding;GO:0030528:transcription regulator activity; GO:0006355:regulation of transcription, DNA-dependent;GO:0007275:multicellular organismal development;GO:0030154:cell differentiation; GO:0005634:nucleus;GO:0005737:cytoplasm; --- >prot|ENSP00000334157|cod|ENST00000335355|gene|ENSG00000133612|ann|Arf-GAP, GTPase, ANK repeat and PH domain-containing protein 3 (AGAP-3)(Centaurin-gamma-3)(MR1-interacting protein)(MRIP-1)(CRAM-associated GTPase)(CRAG) [Source:UniProtKB/Swiss-Prot;Acc:Q96P47] 875 1 QSPQQQQQ 8 75 5 0.625 9 16 1 MNFQAGGGQSPQQQQQLAGGPPQQFALSNS LAGGPPQQFALSNSAAIRAEIQRFESVHPN GO:0005525:GTP binding; GO:0007264:small GTPase mediated signal transduction;GO:0015031:protein transport; GO:0005622:intracellular; --- >prot|ENSP00000366283|cod|ENST00000325089|gene|ENSG00000165300|ann|SLIT and NTRK-like protein 5 Precursor (Leucine-rich repeat-containing protein 11) [Source:UniProtKB/Swiss-Prot;Acc:O94991] 958 1 QQQQQ 5 100 5 1 793 797 82 PIYRSREGNSVEDYKDLHELKVTYSSNHHL PPPPPQQPQQQPPPQLQLQPGEEERRESHH GO:0005515:protein binding; GO:0007409:axonogenesis; GO:0016020:membrane;GO:0016021:integral to membrane; --- >prot|ENSP00000301067|cod|ENST00000301067|gene|ENSG00000167548|ann|Histone-lysine N-methyltransferase MLL2 (EC 2.1.1.43)(Myeloid/lymphoid or mixed-lineage leukemia protein 2)(ALL1-related protein)(Lysine N-methyltransferase 2B) [Source:UniProtKB/Swiss-Prot;Acc:O14686] 5537 11 QQQQQQLWQQQQ 12 83.3333333333333 6 0.5 2811 2822 50 PSSMDVNSRQLVGGSQAFYQRAPYPGSLPL ATAATSMRFAMSARFPSTPGPELGRQALGS GO:0003677:DNA binding;GO:0005515:protein binding;GO:0008168:methyltransferase activity;GO:0008270:zinc ion binding;GO:0016740:transferase activity;GO:0018024:histone-lysine N-methyltransferase activity;GO:0046872:metal ion binding;GO:0000150:recombinase activity; GO:0001701:in utero embryonic development;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0016568:chromatin modification;GO:0031424:keratinization;GO:0007242---GO:0006310:DNA recombination; GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0035097:histone methyltransferase complex; --- >prot|ENSP00000301067|cod|ENST00000301067|gene|ENSG00000167548|ann|Histone-lysine N-methyltransferase MLL2 (EC 2.1.1.43)(Myeloid/lymphoid or mixed-lineage leukemia protein 2)(ALL1-related protein)(Lysine N-methyltransferase 2B) [Source:UniProtKB/Swiss-Prot;Acc:O14686] 5537 11 QLQPAQQQQQQQQQ 14 78.5714285714286 9 0.642857142857143 3269 3282 59 SLVASELPLLIEDLLEHEKKELQKKQQLSA HSLLSAPGPAQAMSLPHEGSSPSLAGSQQQ GO:0003677:DNA binding;GO:0005515:protein binding;GO:0008168:methyltransferase activity;GO:0008270:zinc ion binding;GO:0016740:transferase activity;GO:0018024:histone-lysine N-methyltransferase activity;GO:0046872:metal ion binding;GO:0000150:recombinase activity; GO:0001701:in utero embryonic development;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0016568:chromatin modification;GO:0031424:keratinization;GO:0007242---GO:0006310:DNA recombination; GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0035097:histone methyltransferase complex; --- >prot|ENSP00000301067|cod|ENST00000301067|gene|ENSG00000167548|ann|Histone-lysine N-methyltransferase MLL2 (EC 2.1.1.43)(Myeloid/lymphoid or mixed-lineage leukemia protein 2)(ALL1-related protein)(Lysine N-methyltransferase 2B) [Source:UniProtKB/Swiss-Prot;Acc:O14686] 5537 11 QQQQQQQQQQQQQQ 14 100 14 1 3599 3612 64 EQQSKIQKQLDQVRKQQKEHTNLMAEYRNK HSAVLALSPSQSPRLLTKLPGQLLPGHGLQ GO:0003677:DNA binding;GO:0005515:protein binding;GO:0008168:methyltransferase activity;GO:0008270:zinc ion binding;GO:0016740:transferase activity;GO:0018024:histone-lysine N-methyltransferase activity;GO:0046872:metal ion binding;GO:0000150:recombinase activity; GO:0001701:in utero embryonic development;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0016568:chromatin modification;GO:0031424:keratinization;GO:0007242---GO:0006310:DNA recombination; GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0035097:histone methyltransferase complex; --- >prot|ENSP00000301067|cod|ENST00000301067|gene|ENSG00000167548|ann|Histone-lysine N-methyltransferase MLL2 (EC 2.1.1.43)(Myeloid/lymphoid or mixed-lineage leukemia protein 2)(ALL1-related protein)(Lysine N-methyltransferase 2B) [Source:UniProtKB/Swiss-Prot;Acc:O14686] 5537 11 QQQQQQ 6 100 6 1 3679 3684 66 GGQAGGLRLTPGGMALPGQPGGPFLNTALA HSGGAGSLAGPSGGFFPGNLALRSLGPDSR GO:0003677:DNA binding;GO:0005515:protein binding;GO:0008168:methyltransferase activity;GO:0008270:zinc ion binding;GO:0016740:transferase activity;GO:0018024:histone-lysine N-methyltransferase activity;GO:0046872:metal ion binding;GO:0000150:recombinase activity; GO:0001701:in utero embryonic development;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0016568:chromatin modification;GO:0031424:keratinization;GO:0007242---GO:0006310:DNA recombination; GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0035097:histone methyltransferase complex; --- >prot|ENSP00000301067|cod|ENST00000301067|gene|ENSG00000167548|ann|Histone-lysine N-methyltransferase MLL2 (EC 2.1.1.43)(Myeloid/lymphoid or mixed-lineage leukemia protein 2)(ALL1-related protein)(Lysine N-methyltransferase 2B) [Source:UniProtKB/Swiss-Prot;Acc:O14686] 5537 11 QQQQQQQQQQQ 11 100 11 1 3735 3745 67 ALRSLGPDSRLLQERQLQLQQQRMQLAQKL HLLGQVAIQQQQQQGPGVQTNQALGPKPQG GO:0003677:DNA binding;GO:0005515:protein binding;GO:0008168:methyltransferase activity;GO:0008270:zinc ion binding;GO:0016740:transferase activity;GO:0018024:histone-lysine N-methyltransferase activity;GO:0046872:metal ion binding;GO:0000150:recombinase activity; GO:0001701:in utero embryonic development;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0016568:chromatin modification;GO:0031424:keratinization;GO:0007242---GO:0006310:DNA recombination; GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0035097:histone methyltransferase complex; --- >prot|ENSP00000301067|cod|ENST00000301067|gene|ENSG00000167548|ann|Histone-lysine N-methyltransferase MLL2 (EC 2.1.1.43)(Myeloid/lymphoid or mixed-lineage leukemia protein 2)(ALL1-related protein)(Lysine N-methyltransferase 2B) [Source:UniProtKB/Swiss-Prot;Acc:O14686] 5537 11 QQQQQQ 6 100 6 1 3754 3759 67 QQQRMQLAQKLQQQQQQQQQQQHLLGQVAI GPGVQTNQALGPKPQGLMPPSSHQGLLVQQ GO:0003677:DNA binding;GO:0005515:protein binding;GO:0008168:methyltransferase activity;GO:0008270:zinc ion binding;GO:0016740:transferase activity;GO:0018024:histone-lysine N-methyltransferase activity;GO:0046872:metal ion binding;GO:0000150:recombinase activity; GO:0001701:in utero embryonic development;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0016568:chromatin modification;GO:0031424:keratinization;GO:0007242---GO:0006310:DNA recombination; GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0035097:histone methyltransferase complex; --- >prot|ENSP00000301067|cod|ENST00000301067|gene|ENSG00000167548|ann|Histone-lysine N-methyltransferase MLL2 (EC 2.1.1.43)(Myeloid/lymphoid or mixed-lineage leukemia protein 2)(ALL1-related protein)(Lysine N-methyltransferase 2B) [Source:UniProtKB/Swiss-Prot;Acc:O14686] 5537 11 QQQQQQQQHQQQ 12 91.6666666666667 8 0.666666666666667 3856 3867 69 QVLMTQSRVLSSPQLAQQGQGLMGHRLVTA GSMAGLSHLQQSLMSHSGQPKLSAQPMGSL GO:0003677:DNA binding;GO:0005515:protein binding;GO:0008168:methyltransferase activity;GO:0008270:zinc ion binding;GO:0016740:transferase activity;GO:0018024:histone-lysine N-methyltransferase activity;GO:0046872:metal ion binding;GO:0000150:recombinase activity; GO:0001701:in utero embryonic development;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0016568:chromatin modification;GO:0031424:keratinization;GO:0007242---GO:0006310:DNA recombination; GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0035097:histone methyltransferase complex; --- >prot|ENSP00000301067|cod|ENST00000301067|gene|ENSG00000167548|ann|Histone-lysine N-methyltransferase MLL2 (EC 2.1.1.43)(Myeloid/lymphoid or mixed-lineage leukemia protein 2)(ALL1-related protein)(Lysine N-methyltransferase 2B) [Source:UniProtKB/Swiss-Prot;Acc:O14686] 5537 11 QQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQ 83 81.9277108433735 10 0.120481927710843 3898 3980 70 GSMAGLSHLQQSLMSHSGQPKLSAQPMGSL SRTLLSPQQQQQQQVALGPGMPAKPLQHFS GO:0003677:DNA binding;GO:0005515:protein binding;GO:0008168:methyltransferase activity;GO:0008270:zinc ion binding;GO:0016740:transferase activity;GO:0018024:histone-lysine N-methyltransferase activity;GO:0046872:metal ion binding;GO:0000150:recombinase activity; GO:0001701:in utero embryonic development;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0016568:chromatin modification;GO:0031424:keratinization;GO:0007242---GO:0006310:DNA recombination; GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0035097:histone methyltransferase complex; --- >prot|ENSP00000301067|cod|ENST00000301067|gene|ENSG00000167548|ann|Histone-lysine N-methyltransferase MLL2 (EC 2.1.1.43)(Myeloid/lymphoid or mixed-lineage leukemia protein 2)(ALL1-related protein)(Lysine N-methyltransferase 2B) [Source:UniProtKB/Swiss-Prot;Acc:O14686] 5537 11 QQQQQQQ 7 100 7 1 3988 3994 72 QQQQQQQQFQQQQQQQQMGLLNQSRTLLSP VALGPGMPAKPLQHFSSPGALGPTLLLTGK GO:0003677:DNA binding;GO:0005515:protein binding;GO:0008168:methyltransferase activity;GO:0008270:zinc ion binding;GO:0016740:transferase activity;GO:0018024:histone-lysine N-methyltransferase activity;GO:0046872:metal ion binding;GO:0000150:recombinase activity; GO:0001701:in utero embryonic development;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0016568:chromatin modification;GO:0031424:keratinization;GO:0007242---GO:0006310:DNA recombination; GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0035097:histone methyltransferase complex; --- >prot|ENSP00000301067|cod|ENST00000301067|gene|ENSG00000167548|ann|Histone-lysine N-methyltransferase MLL2 (EC 2.1.1.43)(Myeloid/lymphoid or mixed-lineage leukemia protein 2)(ALL1-related protein)(Lysine N-methyltransferase 2B) [Source:UniProtKB/Swiss-Prot;Acc:O14686] 5537 11 QQQQQ 5 100 5 1 4100 4104 74 SGDSQLLLVQPQPQPQPSSLQLQPPLRLPG VSLLHTAGGGSHGQLGSGSSSEASSVPHLL GO:0003677:DNA binding;GO:0005515:protein binding;GO:0008168:methyltransferase activity;GO:0008270:zinc ion binding;GO:0016740:transferase activity;GO:0018024:histone-lysine N-methyltransferase activity;GO:0046872:metal ion binding;GO:0000150:recombinase activity; GO:0001701:in utero embryonic development;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0016568:chromatin modification;GO:0031424:keratinization;GO:0007242---GO:0006310:DNA recombination; GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0035097:histone methyltransferase complex; --- >prot|ENSP00000301067|cod|ENST00000301067|gene|ENSG00000167548|ann|Histone-lysine N-methyltransferase MLL2 (EC 2.1.1.43)(Myeloid/lymphoid or mixed-lineage leukemia protein 2)(ALL1-related protein)(Lysine N-methyltransferase 2B) [Source:UniProtKB/Swiss-Prot;Acc:O14686] 5537 11 QQQQQLQ 7 85.7142857142857 5 0.714285714285714 4217 4223 76 GVGIMPTVGQLRAQLQGVLAKNPQLRHLSP ALLMQRQLQQSQAVRQTPPYQEPGTQTSPL GO:0003677:DNA binding;GO:0005515:protein binding;GO:0008168:methyltransferase activity;GO:0008270:zinc ion binding;GO:0016740:transferase activity;GO:0018024:histone-lysine N-methyltransferase activity;GO:0046872:metal ion binding;GO:0000150:recombinase activity; GO:0001701:in utero embryonic development;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0016568:chromatin modification;GO:0031424:keratinization;GO:0007242---GO:0006310:DNA recombination; GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0035097:histone methyltransferase complex; --- >prot|ENSP00000376071|cod|ENST00000392238|gene|ENSG00000138439|ann|Protein FAM117B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 13 protein) [Source:UniProtKB/Swiss-Prot;Acc:Q6P1L5] 589 1 QLKQQQQQQ 9 77.7777777777778 6 0.666666666666667 42 50 7 TPAGSLGGGAVATAGGPGSRLQPMRATVPF HGSPTRSGGGGGGNNNGGCCGGASGPAGGG --- --- GO:0005634:nucleus; --- >prot|ENSP00000366604|cod|ENST00000377387|gene|ENSG00000168066|ann|Splicing factor 1 (Zinc finger protein 162)(Transcription factor ZFM1)(Zinc finger gene in MEN1 locus)(Mammalian branch point-binding protein mBBP)(BBP) [Source:UniProtKB/Swiss-Prot;Acc:Q15637] 673 1 QQQQQQ 6 100 6 1 626 631 93 PPPPMGMMPPPPPPPSGQPPPPPSGPLPPW PPPPPPPSSSMASSTPLPWQQRSLPAAAMA GO:0003702:RNA polymerase II transcription factor activity;GO:0003714:transcription corepressor activity;GO:0003723:RNA binding;GO:0005515:protein binding;GO:0008270:zinc ion binding;GO:0046872:metal ion binding;GO:0003676:nucleic acid binding;GO:0005249:voltage-gated potassium channel activity; GO:0000245:spliceosome assembly;GO:0000389:nuclear mRNA 3'-splice site recognition;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0008380:RNA splicing;GO:0006813:potassium ion transport; GO:0016021:integral to membrane;GO:0005840:ribosome;GO:0005634:nucleus;GO:0005681:spliceosomal complex; --- >prot|ENSP00000215793|cod|ENST00000215793|gene|ENSG00000099995|ann|Splicing factor 3 subunit 1 (Spliceosome-associated protein 114)(SAP 114)(SF3a120) [Source:UniProtKB/Swiss-Prot;Acc:Q15459] 793 1 QQQQQ 5 100 5 1 118 122 14 DPYHAYYRHKVSEFKEGKAQEPSAAIPKVM TTQQQLPQKVQAQVIQETIVPKEPPPEFEF GO:0003723:RNA binding;GO:0005515:protein binding;GO:0005199:structural constituent of cell wall;GO:0005198:structural molecule activity; GO:0000389:nuclear mRNA 3'-splice site recognition;GO:0000398:nuclear mRNA splicing, via spliceosome;GO:0006464:protein modification process;GO:0008380:RNA splicing;GO:0006396:RNA processing;GO:0007155:cell adhesion; GO:0005634:nucleus;GO:0005684:U2-type spliceosomal complex;GO:0015629:actin cytoskeleton; --- >prot|ENSP00000302669|cod|ENST00000304538|gene|ENSG00000170325|ann|PR domain zinc finger protein 10 (PR domain-containing protein 10)(Tristanin) [Source:UniProtKB/Swiss-Prot;Acc:Q9NQV6] 1023 1 QGQALQQQQQQQQ 13 76.9230769230769 8 0.615384615384615 890 902 86 ASVSGQPLSPSAQQAQQGLSPSHIQGSSST NSSVQHTYLPSAWNSFRGYSSEIQMMTLPP GO:0003676:nucleic acid binding;GO:0008270:zinc ion binding;GO:0003677:DNA binding; --- GO:0005622:intracellular; --- >prot|ENSP00000323152|cod|ENST00000323180|gene|ENSG00000135365|ann|PHD finger protein 21A (BRAF35-HDAC complex protein BHC80)(BHC80a) [Source:UniProtKB/Swiss-Prot;Acc:Q96BD5] 634 1 QQLQQQQQ 8 87.5 5 0.625 93 100 14 IVKQEQPDKFQIQPLPQSENKLQTAQQQPL YHHHHAQQSAAASPNLTASQKTVTTASMIT GO:0003677:DNA binding;GO:0005515:protein binding;GO:0008270:zinc ion binding;GO:0046872:metal ion binding; GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0016568:chromatin modification;GO:0007242--- GO:0000118:histone deacetylase complex;GO:0005634:nucleus; --- >prot|ENSP00000261203|cod|ENST00000261203|gene|ENSG00000111052|ann|Lin-7 homolog A (Lin-7A)(hLin-7)(Mammalian lin-seven protein 1)(MALS-1)(Vertebrate lin-7 homolog 1)(Veli-1 protein)(Tax interaction protein 33)(TIP-33) [Source:UniProtKB/Swiss-Prot;Acc:O14910] 233 1 QQQQLLIQQQQQQQQQQTQQ 20 80 10 0.5 210 229 90 DSVKLVVRYTPKVLEEMEARFEKLRTARRR NHMS GO:0005515:protein binding; GO:0006461:protein complex assembly;GO:0006887:exocytosis;GO:0007269:neurotransmitter secretion;GO:0015031:protein transport;GO:0048489:synaptic vesicle transport; GO:0005886:plasma membrane;GO:0005923:tight junction;GO:0016323:basolateral plasma membrane;GO:0019717:synaptosome;GO:0030054:cell junction;GO:0045202:synapse;GO:0045211:postsynaptic membrane; --- >prot|ENSP00000377721|cod|ENST00000394166|gene|ENSG00000185551|ann|COUP transcription factor 2 (COUP-TF II)(COUP-TF2)(Nuclear receptor subfamily 2 group F member 2)(Apolipoprotein AI regulatory protein 1)(ARP-1) [Source:UniProtKB/Swiss-Prot;Acc:P24468] 414 1 QQQQQ 5 100 5 1 71 75 17 QTPGQGGPASTPAQTAAGGQGGPGGPGSDK HIECVVCGDKSSGKHYGQFTCEGCKSFFKR GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0003706:ligand-regulated transcription factor activity;GO:0003707:steroid hormone receptor activity;GO:0003714:transcription corepressor activity;GO:0008270:zinc ion binding;GO:0043565:sequence-specific DNA binding;GO:0046872:metal ion binding;GO:0003677:DNA binding;GO:0004879:ligand-dependent nuclear receptor activity;GO:0005496:steroid binding;GO:0004887:thyroid hormone receptor activity; GO:0006350:transcription;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0006629:lipid metabolic process;GO:0007165:signal transduction;GO:0006355:regulation of transcription, DNA-dependent; GO:0005634:nucleus; --- >prot|ENSP00000283147|cod|ENST00000283147|gene|ENSG00000153162|ann|Bone morphogenetic protein 6 Precursor (BMP-6) [Source:UniProtKB/Swiss-Prot;Acc:P22004] 513 1 QQEEQQQQQQ 10 80 6 0.6 109 118 21 MQKEILSVLGLPHRPRPLHGLQQPQPPALR LPRGEPPPGRLKSAPLFMLDLYNALSADND GO:0005125:cytokine activity;GO:0005515:protein binding;GO:0008083:growth factor activity; GO:0006954:inflammatory response;GO:0006955:immune response;GO:0007275:multicellular organismal development;GO:0030501:positive regulation of bone mineralization;GO:0030509:BMP signaling pathway;GO:0032349:positive regulation of aldosterone biosynthetic process;GO:0040007:growth;GO:0045669:positive regulation of osteoblast differentiation;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0051216:cartilage development;GO:0030154:cell differentiation;GO:0001649:osteoblast differentiation; GO:0005576:extracellular region;GO:0005615:extracellular space; --- >prot|ENSP00000352567|cod|ENST00000359564|gene|ENSG00000111817|ann|Dermatan-sulfate epimerase Precursor (DS epimerase)(EC 5.1.3.19)(Chondroitin-glucuronate 5-epimerase)(Squamous cell carcinoma antigen recognized by T-cells 2)(SART-2) [Source:UniProtKB/Swiss-Prot;Acc:Q9UL01] 958 1 QQQQQQ 6 100 6 1 798 803 83 ASFRKTAERLLRFSDKRQTEEAIDRIFAIS SKSKKNRRAGKRYKFVDAVPDIFAQIEVNE GO:0016853:isomerase activity;GO:0047757:chondroitin-glucuronate 5-epimerase activity; GO:0030208:dermatan sulfate biosynthetic process; GO:0016020:membrane;GO:0016021:integral to membrane;GO:0005783:endoplasmic reticulum;GO:0005794:Golgi apparatus; --- >prot|ENSP00000384823|cod|ENST00000403359|gene|ENSG00000138081|ann|F-box only protein 11 (Vitiligo-associated protein 1)(VIT-1) [Source:UniProtKB/Swiss-Prot;Acc:Q86XK2] 927 2 QQQQQQPPQQ 10 80 6 0.6 21 30 2 MNSVRAANRRPRRVSRPRPVQQQQQQPPQQ PPPQPPQQQPPQQQPPPPPQQQQQQQPPPP GO:0008270:zinc ion binding;GO:0004842:ubiquitin-protein ligase activity; GO:0007605:sensory perception of sound; GO:0005622:intracellular; --- >prot|ENSP00000384823|cod|ENST00000403359|gene|ENSG00000138081|ann|F-box only protein 11 (Vitiligo-associated protein 1)(VIT-1) [Source:UniProtKB/Swiss-Prot;Acc:Q86XK2] 927 2 QQQQQQQ 7 100 7 1 50 56 5 VQQQQQQPPQQPPPQPPQQQPPQQQPPPPP PPPPPPPPPPLPQERNNVGERDDDVPADMV GO:0008270:zinc ion binding;GO:0004842:ubiquitin-protein ligase activity; GO:0007605:sensory perception of sound; GO:0005622:intracellular; --- >prot|ENSP00000305861|cod|ENST00000302798|gene|ENSG00000157654|ann|Paralemmin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q8IXS6] 1090 1 QKQLQQQQQQ 10 80 6 0.6 512 521 46 EEQLDEEHLESHKKYKERKERRAQQEQLLL PPSQLCTAPASSHERASMIDKAKEDIVTEQ GO:0019899:enzyme binding; --- --- --- >prot|ENSP00000349748|cod|ENST00000357214|gene|ENSG00000116560|ann|Splicing factor, proline- and glutamine-rich (Polypyrimidine tract-binding protein-associated-splicing factor)(PTB-associated-splicing factor)(PSF)(DNA-binding p52/p100 complex, 100 kDa subunit)(100 kDa DNA-pairing protein)(hPOMp100) [Source:UniProtKB/Swiss-Prot;Acc:P23246] 707 1 QQQQQ 5 100 5 1 67 71 9 GMGLNQNRGPMGPGPGQSGPKPPIPPPPPH PPPQQPPPQQPPPHQPPPHPQPHQQQQPPP GO:0000166:nucleotide binding;GO:0003677:DNA binding;GO:0003723:RNA binding;GO:0005515:protein binding;GO:0003676:nucleic acid binding;GO:0005199:structural constituent of cell wall; GO:0006281:DNA repair;GO:0006310:DNA recombination;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0006397:mRNA processing;GO:0006974:response to DNA damage stimulus;GO:0008380:RNA splicing;GO:0007186:G-protein coupled receptor protein signaling pathway; GO:0016021:integral to membrane;GO:0005634:nucleus;GO:0016363:nuclear matrix; --- >prot|ENSP00000225388|cod|ENST00000225388|gene|ENSG00000108256|ann|Nuclear fragile X mental retardation-interacting protein 2 (FMRP-interacting protein 2)(82 kDa FMRP-interacting protein)(82-FIP)(Cell proliferation-inducing gene 1 protein) [Source:UniProtKB/Swiss-Prot;Acc:Q7Z417] 695 1 QQQQQQ 6 100 6 1 24 29 3 MEEKPGQPQPQHHHSHHHPHHHPQQQQQQP PHHHHHYYFYNHSHNHHHHHHHQQPHQYLQ GO:0003723:RNA binding;GO:0005515:protein binding; --- GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0042788:polysomal ribosome; --- >prot|ENSP00000259318|cod|ENST00000259318|gene|ENSG00000241978|ann|Paralemmin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q8IXS6] 859 1 QKQLQQQQQQ 10 80 6 0.6 281 290 32 EEQLDEEHLESHKKYKERKERRAQQEQLLL PPSQLCTAPASSHERASMIDKAKEDIVTEQ --- GO:0008360:regulation of cell shape; GO:0016020:membrane; --- >prot|ENSP00000262435|cod|ENST00000262435|gene|ENSG00000108854|ann|E3 ubiquitin-protein ligase SMURF2 (hSMURF2)(EC 6.3.2.-)(SMAD ubiquitination regulatory factor 2)(SMAD-specific E3 ubiquitin-protein ligase 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9HAU4] 748 1 QQQQQ 5 100 5 1 347 351 46 DHNNRTTQFTDPRLSANLHLVLNRQNQLKD VVSLCPDDTECLTVPRYKRDLVQKLKILRQ GO:0004842:ubiquitin-protein ligase activity;GO:0016874:ligase activity;GO:0016881:acid-amino acid ligase activity;GO:0042802:identical protein binding;GO:0046332:SMAD binding;GO:0005515:protein binding; GO:0006464:protein modification process;GO:0016481:negative regulation of transcription;GO:0017015:regulation of transforming growth factor beta receptor signaling pathway;GO:0030509:BMP signaling pathway;GO:0030579:ubiquitin-dependent SMAD protein catabolic process; GO:0005886:plasma membrane;GO:0000151:ubiquitin ligase complex;GO:0005622:intracellular;GO:0005634:nucleus;GO:0005737:cytoplasm; --- >prot|ENSP00000356868|cod|ENST00000367893|gene|ENSG00000162761|ann|LIM homeobox transcription factor 1-alpha (LIM/homeobox protein LMX1A)(LIM/homeobox protein 1.1)(LMX-1.1) [Source:UniProtKB/Swiss-Prot;Acc:Q8TE12] 382 1 QQQQQQDQQNTQ 12 75 6 0.5 257 268 67 TLAAETGLSVRVVQVWFQNQRAKMKKLARR RLSSAQTNGGGSAGMEGIMNPYTALPTPQQ GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0008270:zinc ion binding;GO:0043565:sequence-specific DNA binding;GO:0046872:metal ion binding;GO:0030528:transcription regulator activity; GO:0006355:regulation of transcription, DNA-dependent;GO:0007275:multicellular organismal development; GO:0005634:nucleus; --- >prot|ENSP00000254616|cod|ENST00000254616|gene|ENSG00000132286|ann|Mitochondrial import inner membrane translocase subunit Tim9 B (TIMM10B)(Tim10b)(Fracture callus protein 1)(FxC1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5J6] 103 1 QQQQQQQ 7 100 7 1 4 10 3 MERQQQQQQQLRNLRDFLLVYNRMTELCFQ LRNLRDFLLVYNRMTELCFQRCVPSLHHRA GO:0008270:zinc ion binding;GO:0046872:metal ion binding; GO:0006626:protein targeting to mitochondrion;GO:0007160:cell-matrix adhesion;GO:0015031:protein transport;GO:0045039:protein import into mitochondrial inner membrane;GO:0065002:intracellular protein transmembrane transport; GO:0016020:membrane;GO:0005739:mitochondrion;GO:0005743:mitochondrial inner membrane;GO:0042719:mitochondrial intermembrane space protein transporter complex; --- >prot|ENSP00000251636|cod|ENST00000251636|gene|ENSG00000067248|ann|ATP-dependent RNA helicase DHX29 (EC 3.6.1.-)(DEAH box protein 29)(Nucleic acid helicase DDXx) [Source:UniProtKB/Swiss-Prot;Acc:Q7Z478] 1369 1 QQQQQQQQ 8 100 8 1 501 508 36 DAEKKREELNKMETNKPRDLFIAKLLNKLK HSENKRENSEDPEESWENLVSDEDFSALSL GO:0000166:nucleotide binding;GO:0003676:nucleic acid binding;GO:0003743:translation initiation factor activity;GO:0004386:helicase activity;GO:0005524:ATP binding;GO:0008026:ATP-dependent helicase activity;GO:0016787:hydrolase activity; GO:0006412:translation; GO:0005737:cytoplasm; --- >prot|ENSP00000360491|cod|ENST00000371436|gene|ENSG00000124813|ann|Runt-related transcription factor 2 (Core-binding factor subunit alpha-1)(CBF-alpha-1)(Acute myeloid leukemia 3 protein)(Oncogene AML-3)(Polyomavirus enhancer-binding protein 2 alpha A subunit)(PEBP2-alpha A)(PEA2-alpha A)(SL3-3 enhancer factor 1 alpha A subunit)(SL3/AKV core-binding factor alpha A subunit)(Osteoblast-specific transcription factor 2)(OSF-2) [Source:UniProtKB/Swiss-Prot;Acc:Q13950] 485 1 QQQQQQQQQQQQQQQQQQQQQQQ 23 100 23 1 35 57 7 VDPSTSRRFSPPSSSLQPGKMSDVSPVVAA EAAAAAAAAAAAAAAAAAVPRLRPPHDNRT GO:0003677:DNA binding;GO:0005524:ATP binding;GO:0050825:ice binding;GO:0003700:sequence-specific DNA binding transcription factor activity; GO:0006355:regulation of transcription, DNA-dependent;GO:0042309:homoiothermy;GO:0050826:response to freezing;GO:0045449:regulation of transcription; GO:0005634:nucleus; 119600: CLEIDOCRANIAL DYSPLASIA; >prot|ENSP00000334414|cod|ENST00000334944|gene|ENSG00000168066|ann|Splicing factor 1 (Zinc finger protein 162)(Transcription factor ZFM1)(Zinc finger gene in MEN1 locus)(Mammalian branch point-binding protein mBBP)(BBP) [Source:UniProtKB/Swiss-Prot;Acc:Q15637] 638 1 QQQQQQ 6 100 6 1 501 506 78 PPPPMGMMPPPPPPPSGQPPPPPSGPLPPW PPPPPPPSSSMASSTPLPWQQNTTTTTTSA GO:0003702:RNA polymerase II transcription factor activity;GO:0003714:transcription corepressor activity;GO:0003723:RNA binding;GO:0005515:protein binding;GO:0008270:zinc ion binding;GO:0046872:metal ion binding;GO:0003676:nucleic acid binding;GO:0005249:voltage-gated potassium channel activity; GO:0000245:spliceosome assembly;GO:0000389:nuclear mRNA 3'-splice site recognition;GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0008380:RNA splicing;GO:0006813:potassium ion transport; GO:0016021:integral to membrane;GO:0005840:ribosome;GO:0005634:nucleus;GO:0005681:spliceosomal complex; --- >prot|ENSP00000264883|cod|ENST00000264883|gene|ENSG00000138750|ann|Nucleoporin p54 (54 kDa nucleoporin) [Source:UniProtKB/Swiss-Prot;Acc:Q7Z3B4] 507 1 QQQQQ 5 100 5 1 93 97 18 FGTGFGTTTGTSTGLGTGLGTGLGFGGFNT TTLGGLFSQPTQAPTQSNQLINTASALSAP GO:0005487:nucleocytoplasmic transporter activity;GO:0005515:protein binding; GO:0006605:protein targeting;GO:0006913:nucleocytoplasmic transport;GO:0015031:protein transport;GO:0051028:mRNA transport;GO:0065002:intracellular protein transmembrane transport; GO:0016020:membrane;GO:0005634:nucleus;GO:0005643:nuclear pore;GO:0005737:cytoplasm;GO:0005654:nucleoplasm;GO:0031965:nuclear membrane; --- >prot|ENSP00000304689|cod|ENST00000303596|gene|ENSG00000168286|ann|THAP domain-containing protein 11 [Source:UniProtKB/Swiss-Prot;Acc:Q96EK4] 314 1 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 29 100 29 1 104 132 33 VRVPTIFPLRGVNERKVARRPAGAAAARRR SSPSASTAQTAQLQPNLVSASAAVLLTLQA GO:0003677:DNA binding;GO:0008270:zinc ion binding;GO:0042802:identical protein binding;GO:0046872:metal ion binding;GO:0050825:ice binding;GO:0003676:nucleic acid binding; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0042309:homoiothermy;GO:0050826:response to freezing; GO:0005634:nucleus;GO:0005737:cytoplasm; --- >prot|ENSP00000334879|cod|ENST00000334306|gene|ENSG00000186212|ann|Ankyrin repeat domain-containing protein 56 [Source:UniProtKB/Swiss-Prot;Acc:A6NEL2] 793 1 QQQQQ 5 100 5 1 300 304 37 ASPPALLPGPAPRGDRPELLTPSSLHYSTL RTREWVARHPQVPEARDQGPIRAWSVLPDN GO:0005215:transporter activity; GO:0006810:transport; GO:0016020:membrane; --- >prot|ENSP00000375941|cod|ENST00000392091|gene|ENSG00000112592|ann|TATA-box-binding protein (TATA-box factor)(TATA-binding factor)(TATA sequence-binding protein)(Transcription initiation factor TFIID TBP subunit) [Source:UniProtKB/Swiss-Prot;Acc:P20226] 316 1 QQRQQQQQQQQQQQQQQQ 18 94.4444444444444 15 0.833333333333333 55 72 17 IPIFSPMMPYGTGLTPQPIQNTNSLSILEE AVAAAAVQQSTSQQATQGTSGQAPQLFHSQ GO:0003677:DNA binding;GO:0003702:RNA polymerase II transcription factor activity; GO:0006355:regulation of transcription, DNA-dependent;GO:0006367:transcription initiation from RNA polymerase II promoter; GO:0005634:nucleus;GO:0005669:transcription factor TFIID complex; --- >prot|ENSP00000198939|cod|ENST00000198939|gene|ENSG00000085872|ann|Calcium homeostasis endoplasmic reticulum protein (SR-related CTD associated factor 6)(ERPROT 213-21) [Source:UniProtKB/Swiss-Prot;Acc:Q8IWX8] 916 1 QQQQQQQQQQQQLQMPQ 17 82.3529411764706 12 0.705882352941177 330 346 36 SSVVQPVQLAFQQQIQTLKTQHEEFVTSLA MEAEVKATPPPPAPPPAPAPAPAIPPTTQP GO:0003674:molecular_function;GO:0003723:RNA binding;GO:0003676:nucleic acid binding;GO:0003677:DNA binding;GO:0004879:ligand-dependent nuclear receptor activity; GO:0006396:RNA processing;GO:0007399:nervous system development;GO:0008150:biological_process;GO:0006355:regulation of transcription, DNA-dependent; GO:0005622:intracellular;GO:0005783:endoplasmic reticulum;GO:0005575:cellular_component;GO:0005634:nucleus;GO:0005737:cytoplasm; --- >prot|ENSP00000327563|cod|ENST00000331217|gene|ENSG00000184384|ann|Mastermind-like protein 2 (Mam-2) [Source:UniProtKB/Swiss-Prot;Acc:Q8IZL2] 985 1 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQ 90 78.8888888888889 34 0.377777777777778 417 506 42 PLFHFNSDQANQQMPSVLPSQNKPSLLHYT PLLRSPLPLQQKLLLQQMQNQPIAGMGYQV GO:0003713:transcription coactivator activity; GO:0006350:transcription;GO:0006355:regulation of transcription, DNA-dependent;GO:0007219:Notch signaling pathway;GO:0045944:positive regulation of transcription from RNA polymerase II promoter; GO:0005634:nucleus;GO:0016607:nuclear speck; --- >prot|ENSP00000340917|cod|ENST00000342943|gene|ENSG00000143502|ann|Sushi domain-containing protein 4 Precursor [Source:UniProtKB/Swiss-Prot;Acc:Q5VX71] 106 1 QQQQQQQPQSPQ 12 75 7 0.583333333333333 16 27 15 MYHGMNPSNGDGFLEQQQQQQQPQSPQRLL RLLAVILWFQLALCFGPAQLTGVHLTRDLL --- --- GO:0016020:membrane;GO:0016021:integral to membrane; --- >prot|ENSP00000384606|cod|ENST00000405995|gene|ENSG00000130723|ann|Protein BAT2-like (HLA-B-associated transcript 2-like) [Source:UniProtKB/Swiss-Prot;Acc:Q5JSZ5] 1535 1 QRQQQQQQQEQ 11 81.8181818181818 7 0.636363636363636 629 639 40 AQSNSSEEEAREAGSPAQEFKYQKSLPPRF LYKMQHWQPVYPPPSHPQRTFYPHHPQMLG --- --- --- --- >prot|ENSP00000357251|cod|ENST00000368268|gene|ENSG00000214338|ann|Uncharacterized protein C6orf174 Precursor [Source:UniProtKB/Swiss-Prot;Acc:Q5TF21] 947 1 QQQLQQQQQQ 10 90 6 0.6 72 81 7 PARPRDSSLRQTIAATRSPVGAGTKLNSVR GNKTGSRTGPPASIRGGGGGAEKATPLAPK GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0043565:sequence-specific DNA binding; GO:0007186:G-protein coupled receptor protein signaling pathway;GO:0006355:regulation of transcription, DNA-dependent; GO:0016020:membrane;GO:0016021:integral to membrane; --- >prot|ENSP00000356422|cod|ENST00000367452|gene|ENSG00000116750|ann|Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5)(EC 3.4.19.12)(Ubiquitin thioesterase L5)(Ubiquitin C-terminal hydrolase UCH37) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5K5] 165 1 QRQPQQQQQ 9 77.7777777777778 5 0.555555555555556 106 114 64 YLAADPLDPQRRQEKSCAALGNDKRRQPDG PHCRRGFQAPALPNPLRVLQGLGRVSMSLG GO:0004221:ubiquitin thiolesterase activity;GO:0005515:protein binding;GO:0008233:peptidase activity;GO:0008234:cysteine-type peptidase activity; GO:0006511:ubiquitin-dependent protein catabolic process; GO:0005622:intracellular;GO:0005829:cytosol;GO:0043234:protein complex; --- >prot|ENSP00000321976|cod|ENST00000317951|gene|ENSG00000179846|ann|NTPase KAP family P-loop domain-containing protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q17RQ9] 619 1 QQQQQQ 6 100 6 1 424 429 68 ERDCLYEYVPDNVVSMRRIVNTVPITVRLL GDFGGPTPRQAVAWVVLANQWPCRLSWALQ --- --- GO:0016020:membrane;GO:0016021:integral to membrane; --- >prot|ENSP00000205061|cod|ENST00000205061|gene|ENSG00000090863|ann|Golgi apparatus protein 1 Precursor (Golgi sialoglycoprotein MG-160)(E-selectin ligand 1)(ESL-1)(Cysteine-rich fibroblast growth factor receptor)(CFR-1) [Source:UniProtKB/Swiss-Prot;Acc:Q92896] 1203 1 QLQQQQQQQQQQQQPQPPQ 19 78.9473684210526 12 0.631578947368421 71 89 5 GPGANFVSFVGQAGGGGPAGQQLPQLPQSS PPFPAGGPPARRGGAGAGGGWKLAEEESCR GO:0005102:receptor binding; --- GO:0000139:Golgi membrane;GO:0016020:membrane;GO:0016021:integral to membrane;GO:0005794:Golgi apparatus; --- >prot|ENSP00000276185|cod|ENST00000276185|gene|ENSG00000147234|ann|FERM and PDZ domain-containing protein 3 [Source:UniProtKB/Swiss-Prot;Acc:Q5JV73] 1810 1 QQQQQQQQQQQQQQQQQQQQQQQQQQQ 27 100 27 1 1750 1776 96 QELLAKVEEVVRNYTFLLRAAEESTARNLN VAAAAGAATEHPPGSPTSATVMSTFTHSLK GO:0005515:protein binding; GO:0007165:signal transduction; GO:0005739:mitochondrion;GO:0005856:cytoskeleton; ---